Patents by Inventor Yong Ji

Yong Ji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200377550
    Abstract: Provided are a peptide with a cytoprotective effect against environmental pollutants and a use thereof. The peptide consisting of an amino acid sequence of SEQ ID NO: 1, 2, or 3 directly binds to 2,3,7,8-tetrachlorodibenzo-p-dioxin (hereinafter, referred to as TCDD), known as being the most toxic among the class of dioxins, to prevent dermal penetration and the activation mechanism of AhR by TCDD and polycyclic aromatic hydrocarbons contained in fine dust. Such a direct cytoprotective effect against environmental pollutants is distinguished from preexisting methods that are configured to indirectly block opportunities to contact these materials or to reduce toxicity through barrier reinforcement.
    Type: Application
    Filed: February 14, 2018
    Publication date: December 3, 2020
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung-ji LEE
  • Publication number: 20200331967
    Abstract: The peptide of the present invention performs a function, which is the same as or similar to that of natural interleukin (IL)-3, and has superior skin permeability due to the small size thereof. In addition, the peptide of the present invention suppresses the activation of NF-?B and nuclear transition by inhibiting the receptor activator of nuclear factor kappa-B ligand (RANKL)-RANK signaling pathway, and suppresses the expression of a RANKL or an inflammatory cytokine-induced tartrate-resistant acid phosphatase (TRAP), cathepsin K, or TNF receptor type 1 or type 2, thereby inhibiting osteoclast differentiation depending on the treatment concentration. Moreover, the peptide of the present invention can contribute to osteoblast differentiation by promoting the expression of osteoblast differentiation markers such as osteocalcin (OCN), osteoprotegerin (OPG), bone sialoprotein (BSP), or osteopontin (OPN).
    Type: Application
    Filed: April 21, 2020
    Publication date: October 22, 2020
    Inventors: Yong Ji CHUNG, Eun Mi Kim, Eung Ji Lee, Tae-Hoon Lee, A-Reum Han
  • Publication number: 20200330546
    Abstract: The present invention relates to a hangover alleviating composition containing a conjugate of sesamol and a peptide as an active ingredient. Specifically, the conjugate of sesamol and a peptide according to the present invention significantly increases the activity of alcohol dehydrogenase (ADH) or aldehyde dehydrogenase (ALDH) involved in the alcohol metabolising process, quickly breaks down the concentration of alcohol in the body, and improves alcohol-induced motor impairment, thus having the advantage of being able to be usefully used as an active ingredient in a hangover alleviating composition.
    Type: Application
    Filed: October 16, 2018
    Publication date: October 22, 2020
    Applicant: CAREGEN CO., LTD.
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung Ji LEE
  • Publication number: 20200289526
    Abstract: The present invention relates to a composition for preventing hair loss and, more specifically, to a compound having a structure in which finasteride and a peptide are linked through a covalent bond and a pharmaceutical composition or a cosmetic composition for preventing hair loss or promoting hair growth comprising the same. The compound of the present invention having a structure in which finasteride and a peptide are linked through a covalent bond is excellent in physiological activities such as hair loss improvement, hair growth promotion, cell growth promotion, etc., is excellent in stability in water and skin permeation, and thus can be effectively used as a composition for preventing hair loss and promoting hair growth.
    Type: Application
    Filed: May 20, 2016
    Publication date: September 17, 2020
    Inventors: Yong Ji CHUNG, Eun Mi KIM
  • Publication number: 20200277332
    Abstract: The present invention relates to a novel peptide having an angiogenesis inhibitory activity and a use of the peptide, related to the treatment or prevention of excessive angiogenesis-related diseases. Particularly, a novel peptide according to the present invention binds, in competition with vascular endothelial growth factors (VEGF), to VEGF receptors and can significantly inhibit the proliferation, migration and differentiation of vascular endothelial cells, thereby being effectively usable as an active ingredient of a composition or a health functional food for preventing or treating diseases, such as macular degeneration, a tumor, arthritis or psoriasis, caused by excessive angiogenesis.
    Type: Application
    Filed: March 14, 2018
    Publication date: September 3, 2020
    Applicant: CAREGEN CO., LTD.
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung Ji LEE
  • Patent number: 10738081
    Abstract: A peptide and a peptide complex of the present invention exhibit an anti-obesity effect by inhibiting fat accumulation and decomposing already accumulated fat, and exhibit an excellent effect with respect to diabetes by effectively reducing blood sugar. The peptide and the peptide complex of the present invention decrease the expression of PPAR?, ACC, and aP2, which are adipogenic markers, increase the expression of pHSL, AMPK-?1, CGI-58, and ATGL, which are lipolytic factors, and reduce the size of fat cells and blood cholesterol values. The peptide and the peptide complex of the present invention, which have excellent activity and safety, can be advantageously applied to drugs and quasi-drugs.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: August 11, 2020
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim
  • Publication number: 20200246473
    Abstract: The present invention relates to a compound having a structure in which isotretinoin is linked to a peptide via a covalent bond and an antibiotic, anti-inflammatory, or anti-oxidative pharmaceutical or cosmetic composition comprising the same. A compound having a structure in which isotretinoin is linked to a peptide via a covalent bond according to the present invention exhibits excellent physiological activity such as antibiotic, anti-inflammatory, or anti-oxidative actions, as well as having outstanding properties, such as solubility in water, etc., and thus can find useful applications in various fields including medicines, cosmetics, etc.
    Type: Application
    Filed: May 11, 2018
    Publication date: August 6, 2020
    Applicant: CAREGEN CO., LTD.
    Inventors: Yong Ji CHUNG, Eun Mi KIM
  • Patent number: 10723777
    Abstract: The present disclosure relates to peptides exhibiting an anti-obesity effect by inhibiting fat accumulation and decomposing already accumulated fats as well as an outstanding anti-diabetes effect by effectively lowering blood sugar levels. The peptides that downregulate the expression of the adipogenic markers PPAR?, ACC and/or aP2, upregulate the expression of the lipolytic factors pHSL, AMPK-?1, CGI-58 and/or ATGL, and reduce sizes of adipocyte and levels of cholesterol in blood are described. The excellent activity and stability of the peptides described herein provides advantages in applications such as drugs and quasi-drug products.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: July 28, 2020
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim
  • Patent number: 10695279
    Abstract: The present invention provides a peptide having skin-whitening activity. The peptide of the present invention exhibits an excellent skin whitening effect by inhibiting melanogenesis, inhibiting the activity of tyrosinase, inhibiting the expression of melanosis-involved factors, and inhibiting melanosome transfer. The peptide of the present invention has excellent skin permeability due to the small size thereof. Excellent activity and stability of the foregoing peptide of the present invention can be very favorably applied to cosmetics.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: June 30, 2020
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim, Eung-Ji Lee, Jan Di Kim
  • Publication number: 20200197285
    Abstract: The present disclosure relates to a peptide consisting of an amino acid sequence of SEQ ID NO: 1, 2, 3, or 4, a pharmaceutical composition for preventing or treating skin disease including the peptide, a cosmetic composition for skin condition improvement including the peptide, a food composition for skin condition improvement including the peptide, a method of preventing or treating skin disease using the peptide, and a use of the peptide in preventing or treating skin disease or improving skin condition.
    Type: Application
    Filed: July 3, 2018
    Publication date: June 25, 2020
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung Ji LEE
  • Patent number: 10682027
    Abstract: A heated seat having a thermally conductive metal seat, a protective coating disposed on a top surface of the metal seat, and a thermally conductive water pipe in the thermally conductive metal seat. Hot water can be routed through the water pipe to heat the seat. This arrangement improves safety and enables the heat from the hot water to be rapidly conducted through the seat, thereby improving the comfort in use.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: June 16, 2020
    Assignee: SHANGHAI KOHLER ELECTRONICS, LTD.
    Inventor: Yong Ji
  • Patent number: 10669312
    Abstract: The peptide of the present invention performs a function, which is the same as or similar to that of natural interleukin (IL)-3, and has superior skin permeability due to the small size thereof. In addition, the peptide of the present invention suppresses the activation of NF-?B and nuclear transition by inhibiting the receptor activator of nuclear factor kappa-B ligand (RANKL)-RANK signaling pathway, and suppresses the expression of a RANKL or an inflammatory cytokine-induced tartrate-resistant acid phosphatase (TRAP), cathepsin K, or TNF receptor type 1 or type 2, thereby inhibiting osteoclast differentiation depending on the treatment concentration. Moreover, the peptide of the present invention can contribute to osteoblast differentiation by promoting the expression of osteoblast differentiation markers such as osteocalcin (OCN), osteoprotegerin (OPG), bone sialoprotein (BSP), or osteopontin (OPN).
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: June 2, 2020
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong-Ji Chung, Eun-Mi Kim, Eung-Ji Lee, Tae-Hoon Lee, A-Reum Han
  • Publication number: 20200148721
    Abstract: The present invention provides a peptide exhibiting melanogenesis promoting activity. A peptide according to the present invention increases the activity and expression of tyrosinase and the expression of factors involved in melanogenesis, thereby exhibiting an outstanding effect on melanogenesis. The peptide of the present invention can be used for the prevention, alleviation, and treatment of hypomelanosis. The outstanding activity and stability stated above allow the peptide of the present invention to be very favorably applied to medicines, quasi-medicines, and cosmetics.
    Type: Application
    Filed: February 21, 2018
    Publication date: May 14, 2020
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung-Ji LEE
  • Patent number: 10626145
    Abstract: A peptide and a peptide complex of the present invention exhibit an anti-obesity effect by inhibiting fat accumulation and decomposing already accumulated fat, and exhibit an excellent effect with respect to diabetes by effectively reducing blood sugar. The peptide and the peptide complex of the present invention decrease the expression of PPAR?, ACC, and aP2, which are adipogenic markers, increase the expression of pHSL, AMPK-?1, CGI-58, and ATGL, which are lipolytic factors, and reduce the size of fat cells and blood cholesterol values. The peptide and the peptide complex of the present invention, which have excellent activity and safety, can be advantageously applied to drugs and quasi-drugs.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: April 21, 2020
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim
  • Patent number: 10579556
    Abstract: A method, computer program product, and system includes a processing circuit(s) allocating a page of system memory address space to a device. The allocating includes the processing circuits(s) obtaining base address registers of the device in a bus and determining a portion of the page of the system memory address space to allocate to the base address registers. The processing circuits(s) sorts the base address registers, in a descending order, according to their alignments and adds sizes of the sorted base address registers to determine the portion of the page. The processing circuit(s) determines a remainder of the page: a difference between a size of the page and the portion of the page. The processing circuit(s) requests a virtual resource of a size equal to the remainder and allocates the page to the sorted base address registers and to the virtual resource.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: March 3, 2020
    Assignee: International Business Machines Corporation
    Inventors: Bo Qun Bq Feng, Zhong Li, Xian Dong Meng, Yong Ji Jx Xie
  • Patent number: 10580755
    Abstract: A fan-out wafer level multilayer wiring package structure, wherein the package structure comprises a plurality of semiconductor chips, a multilayer interposer, a vertical interconnection interposer, molding materials and a redistribution layer; the back surface of the semiconductor chip is bonded to the back surface of the multilayer wiring interposer with the bonding material, and is placed on the same horizontal plane as the vertical interconnection interposer and packaged as a whole with the molding material, the redistribution layer is provided on the surface of the structure; the semiconductor chip, the multilayer interposer, the conductive material of the vertical interconnection interproser and the solder ball are connected by the conductive metal layer of the redistribution layer to achieve the signal interconnection between the semiconductor chip and the multilayer interposer and the I/O signal transfer of the semiconductor chip.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: March 3, 2020
    Assignee: The 58th Research Institute of China Electronics Technology Group Corporation
    Inventors: Yong Ji, Rongzhen Zhang, Chongchong Mao
  • Patent number: 10568828
    Abstract: The present invention provides a peptide which shows a hair growth-promoting activity. The peptide of the present invention promotes the growth of follicular cells and increases the expression of a hair growth-related growth factor and hair growth-related factors, thereby showing an excellent effect in hair growth. The peptide of the present invention can be used for preventing and alleviating hair loss, promoting hair growth, and improving hair growth. In addition, the superior activity and stability of the peptide of the present invention allows the peptide to be very favorably applied to quasi drugs and cosmetics.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: February 25, 2020
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim, Eung-Ji Lee, Min Woong Kim
  • Publication number: 20200048323
    Abstract: The peptide of the present invention exhibits an anti-obesity effect by inhibiting fat accumulation and decomposing already accumulated fats as well as an outstanding anti-diabetes effect by effectively lowering blood sugar levels. The peptide of the present invention downregulates the expression of the adipogenic markers PPAR?, ACC and/or aP2, upregulates the expression of the lipolytic factors pHSL, AMPK-?1. CGI-58 and/or ATGL, and reduces sizes of adipocyte and levels of cholesterol in blood. The excellent activity and stability of the peptide of the present invention may be very advantageously applied to drugs and quasi-drug products.
    Type: Application
    Filed: March 29, 2017
    Publication date: February 13, 2020
    Applicant: CAREGEN CO., LTD.
    Inventors: Yong Ji CHUNG, Eun Mi KIM
  • Patent number: 10547619
    Abstract: An USB device includes: a wireless communication unit; a storage unit configured for storing a driving program, a driving application, a driving command, and/or data received from an external information device and/or a server therein; and a control unit configured for controlling the wireless communication unit, the storage unit, wherein the control unit includes: a data processor configured for controlling a data processing operation using the driving program, the driving application or the driving command; and a transmission controller configured for: receiving data from the information device under control of the data processor; and selectively allowing or disallowing data transmission from the data processor to the information device.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: January 28, 2020
    Inventors: Young Hoon Park, Dae Yong Ji
  • Publication number: 20200014689
    Abstract: An USB device includes: a wireless communication unit; a storage unit configured for storing a driving program, a driving application, a driving command, and/or data received from an external information device and/or a server therein; and a control unit configured for controlling the wireless communication unit, the storage unit, wherein the control unit includes: a data processor configured for controlling a data processing operation using the driving program, the driving application or the driving command; and a transmission controller configured for: receiving data from the information device under control of the data processor; and selectively allowing or disallowing data transmission from the data processor to the information device.
    Type: Application
    Filed: July 8, 2019
    Publication date: January 9, 2020
    Inventors: Young Hoon PARK, Dae Yong JI