Abstract: The present invention provides a peptide having anti-inflammatory activity, composed of an amino acid sequence of a sequence listing of SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3. The peptide inhibits the expression of inflammatory cytokines and inhibits the proliferation of inflammatory cells, so as to resultantly exhibit anti-inflammatory activity, thereby being useful in the prevention or treatment of inflammatory diseases.

Abstract: Provided is a peptide, which has an anti-inflammatory activity and an activity for promoting osteogenic differentiation, formed from the amino acid sequence selected from the group comprising the amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 2, and SEQ ID NO: 3. And provided is a peptide, which has a hair growth promoting activity, formed from the amino acid sequence selected from the group comprising the amino acid sequences of SEQ ID NO: 1 and SEQ ID NO: 2. A peptide formed from the amino acid sequence of SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3, according to the present invention, consequently shows an anti-inflammatory activity by inhibiting an inflammatory cytokine expression and proliferation of inflammatory cells, and consequently promotes osteogenic differentiation by increasing phosphorylation of PI3K, Smad1, Smad5 and Smad8, which contribute to osteogenesis, and by increasing ALP, OPG and BSP expressions.

Abstract: The present invention provides: a peptide which shows a hair growth-promoting activity and/or a melanin generation-promoting activity; a composition for preventing and/or alleviating hair loss, comprising the peptide as an effective ingredient; a composition for promoting hair growth, comprising the peptide as an effective ingredient; a use of the peptide for preventing and/or alleviating hair loss; a use of the peptide for promoting hair growth; a pharmaceutical composition for preventing and/or treating hypomelanosis, comprising the peptide as an effective ingredient; a cosmetic composition for preventing and/or treating hypomelanosis, comprising the peptide as an effective ingredient; and a use of the peptide for preventing and/or treating hypomelanosis.

Abstract: A method, computer program product, and system includes a processing circuit(s) allocating a page of system memory address space to a device. The allocating includes the processing circuits(s) obtaining base address registers of the device in a bus and determining a portion of the page of the system memory address space to allocate to the base address registers. The processing circuits(s) sorts the base address registers, in a descending order, according to their alignments and adds sizes of the sorted base address registers to determine the portion of the page. The processing circuit(s) determines a remainder of the page: a difference between a size of the page and the portion of the page. The processing circuit(s) requests a virtual resource of a size equal to the remainder and allocates the page to the sorted base address registers and to the virtual resource.

Abstract: A fan-out wafer level multilayer wiring package structure, wherein the package structure comprises a plurality of semiconductor chips, a multilayer interposer, a vertical interconnection interposer, molding materials and a redistribution layer; the back surface of the semiconductor chip is bonded to the back surface of the multilayer wiring interposer with the bonding material, and is placed on the same horizontal plane as the vertical interconnection interposer and packaged as a whole with the molding material, the redistribution layer is provided on the surface of the structure; the semiconductor chip, the multilayer interposer, the conductive material of the vertical interconnection interproser and the solder ball are connected by the conductive metal layer of the redistribution layer to achieve the signal interconnection between the semiconductor chip and the multilayer interposer and the I/O signal transfer of the semiconductor chip.

Abstract: The present invention provides a peptide which shows a hair growth-promoting activity. The peptide of the present invention promotes the growth of follicular cells and increases the expression of a hair growth-related growth factor and hair growth-related factors, thereby showing an excellent effect in hair growth. The peptide of the present invention can be used for preventing and alleviating hair loss, promoting hair growth, and improving hair growth. In addition, the superior activity and stability of the peptide of the present invention allows the peptide to be very favorably applied to quasi drugs and cosmetics.

Abstract: The present invention provides a peptide having activity to improve skin condition. The peptide of the present invention exhibits a very excellent effect in improving skin condition by inhibiting MMP2 activity. A composition containing the peptide of the present invention exhibits excellent biological activities, such as inhibiting collagen decomposition and melanosome migration, and thus can be used in wrinkle reduction, skin regeneration, skin elasticity improvement, anti-skin aging, wound regeneration, acne reduction, skin regeneration or skin whitening. The composition containing the peptide of the present invention can be used as a pharmaceutical composition for preventing or treating MMP activity-related diseases and inflammation diseases.

Abstract: A method of bonding a flexible part including inclined leads is provided, and more particularly, a method of bonding a flexible part including inclined leads, in which parts are aligned to bond the parts is provided. According to the method of bonding the flexible part including inclined leads, an electronic part may be easily bonded to a part having an inclined surface.

Abstract: A backflow prevention device including a tank inside of and moveable relative to a housing. A cap coupled to the housing and including inlet and outlet chambers fluidly connected through an inlet, the outlet chamber communicating with the tank. A shell is connected to the cap and includes a shell inlet chamber, which communicates with a first outlet hole of the inlet chamber, and a second outlet hole, which communicates with the tank. An inlet sealing member opens/closes the inlet to fluidly connect/disconnect the inlet chamber and the outlet chamber; and an outlet hole sealing member is moveable with the tank to open/close the second outlet hole. Closing the second outlet hole prevents water from flowing through the second outlet hole and switches the inlet from open to closed. Opening the second outlet hole allows water to flow through the second outlet hole and switches the inlet to open.

Abstract: An apparatus for bonding a flexible part including inclined leads is provided, more particularly, an apparatus for bonding a flexible part including inclined leads, which aligns parts to bond the parts is provided. According to the apparatus for bonding a flexible part including inclined leads, an electronic part may be easily bonded to a part having an inclined surface.

Abstract: A backflow prevention device including a tank having a holding chamber and first and second inlets connected with the holding chamber; a control valve having an intake chamber and first and second discharge chambers connected with the first and second inlets, respectively, the intake chamber connected with the first discharge chamber through a valve inlet; a valve sealing element for opening and closing the valve inlet, the second discharge chamber connected with the intake chamber through a hole of the valve sealing element; a float in the holding chamber; a slide bar in the holding chamber, contacting the float, and moveable toward the second inlet under the action of the float; and a slide bar sealing element for controlling opening and closing of the second inlet. When the second inlet is closed, the valve inlet is closed; and when the second inlet is open, the valve inlet is opened.

Abstract: A peptide formed from the amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 2 shows a melanogenesis increment activity and an adipogenesis inhibitory activity. The peptide, by increasing phosphorylation of MITF, which is a transcription factor for increasing a tyrosinase expression, and CREB for increasing an MITF expression, consequently increases a tyrosinase expression and ultimately increases melanin synthesis. The peptide, by reducing the amount of fat accumulated inside a cell and reducing expressions of perilipin and PPAR?, which contribute to adipogenic mechanism, ultimately inhibits adipogenesis. A composition for remedying or treating melanin hypopigmentation, a composition comprising the peptide, and a pharmaceutical composition for treating or preventing obesity, are provided.

Abstract: A peptide having skin-whitening activity is described. The peptide exhibits an excellent skin whitening effect by inhibiting melanogenesis, inhibiting the activity of tyrosinase, inhibiting the expression of melanosis-involved factors, and inhibiting melanosome transfer. The peptide has excellent skin permeability due to the small size thereof. Excellent activity and stability of the foregoing peptide can be very favorably applied to cosmetics.

Abstract: A peptide having activity to improve skin condition is described. The peptide exhibits a very excellent effect in improving skin condition by inhibiting MMP2 activity. A composition containing the peptide exhibits excellent biological activities, such as inhibiting collagen decomposition and melanosome migration, and thus can be used in wrinkle reduction, skin regeneration, skin elasticity improvement, anti-skin aging, wound regeneration, acne reduction, skin regeneration or skin whitening. The composition containing the peptide can be used as a pharmaceutical composition for preventing or treating MMP activity-related diseases and inflammation diseases.

Abstract: A peptide which is formed from an amino acid sequence selected from the group comprising amino acid sequences of SEQ ID NO: 1 to SEQ ID NO: 3, according to the present invention, has osteoclast differentiation and activation inhibition and is highly effective for preventing or treating bone diseases related to the destruction of the bone. A peptide, according to the present invention, reduces expression of cathepsin K and TRAP related to osteoclast differentiation, inhibits nuclear translocation of NF-kB, and ultimately inhibits osteoclast differentiation. Provided is a composition, for preventing or treating bone diseases, comprising the peptide.

Abstract: The peptide of the present invention performs a function, which is the same as or similar to that of natural interleukin (IL)-3, and has superior skin permeability due to the small size thereof. In addition, the peptide of the present invention suppresses the activation of NF-?B and nuclear transition by inhibiting the receptor activator of nuclear factor kappa-B ligand (RANKL)-RANK signaling pathway, and suppresses the expression of a RANKL or an inflammatory cytokine-induced tartrate-resistant acid phosphatase (TRAP), cathepsin K, or TNF receptor type 1 or type 2, thereby inhibiting osteoclast differentiation depending on the treatment concentration. Moreover, the peptide of the present invention can contribute to osteoblast differentiation by promoting the expression of osteoblast differentiation markers such as osteocalcin (OCN), osteoprotegerin (OPG), bone sialoprotein (BSP), or osteopontin (OPN).

Abstract: A peptide comprising an amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 2, according to the present invention, shows proliferation and differentiation promotion of osteoblast and proliferation and activation promotion of periodontal ligament fibroblast. A peptide, according to the present invention, increases BMP signaling such as SMAD1/5/8 phosphorylation and increases the growth of osteoblast and the expression of a differentiation marker such as COL1A1, BSP and ALP, thereby ultimately showing osteoblast activation. A peptide, according to the present invention, promotes the growth of periodontal ligament fibroblast by means of PI3K and Akt phosphorylation and increases the expression of an activation marker such as COL1A1 and DSPP, thereby ultimately showing periodontal tissue regeneration activation. Provided are a composition for preventing or treating bone diseases and a composition for preventing or treating periodontal diseases, the compositions comprising the aforementioned peptide.

Abstract: A heated seat having a thermally conductive metal seat, a protective coating disposed on a top surface of the metal seat, and a thermally conductive water pipe in the thermally conductive metal seat. Hot water can be routed through the water pipe to heat the seat. This arrangement improves safety and enables the heat from the hot water to be rapidly conducted through the seat, thereby improving the comfort in use.

Abstract: A peptide and a peptide complex of the present invention exhibit an anti-obesity effect by inhibiting fat accumulation and decomposing already accumulated fat, and exhibit an excellent effect with respect to diabetes by effectively reducing blood sugar. The peptide and the peptide complex of the present invention decrease the expression of PPAR?, ACC, and aP2, which are adipogenic markers, increase the expression of pHSL, AMPK-?1, CGI-58, and ATGL, which are lipolytic factors, and reduce the size of fat cells and blood cholesterol values. The peptide and the peptide complex of the present invention, which have excellent activity and safety, can be advantageously applied to drugs and quasi-drugs.

Abstract: The peptide of the present invention performs a function, which is the same as or similar to that of natural interleukin (IL)-3, and has superior skin permeability due to the small size thereof. In addition, the peptide of the present invention suppresses the activation of NF-?B and nuclear transition by inhibiting the receptor activator of nuclear factor kappa-B ligand (RANKL)-RANK signaling pathway, and suppresses the expression of a RANKL or an inflammatory cytokine-induced tartrate-resistant acid phosphatase (TRAP), cathepsin K, or TNF receptor type 1 or type 2, thereby inhibiting osteoclast differentiation depending on the treatment concentration. Moreover, the peptide of the present invention can contribute to osteoblast differentiation by promoting the expression of osteoblast differentiation markers such as osteocalcin (CON), osteoprotegerin (OPG), bone sialoprotein (BSP), or osteopontin (OPN).