Patents by Inventor Yong-Jin Wu

Yong-Jin Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-aryl thiazole derivatives as KCNQ modulators
    Publication number: 20040147401
    Abstract: Novel 2-arylthiazole derivatives of Formula I are described which are openers of KCNQ potassium channels and are useful in the treatment of disorders that are responsive to the opening of the KCNQ potassium channels, including pain and migraine.
    Type: Application
    Filed: December 9, 2003
    Publication date: July 29, 2004
    Inventors: Kenneth M. Boy, Yong-Jin Wu, Jason M. Guernon
  • Aminoalkyl thiazole derivatives as KCNQ modulators
    Publication number: 20040138268
    Abstract: Novel aminoalkylthiazole derivatives of Formula I are described which are openers of KCNQ potassium channels and are useful in the treatment of disorders responsive to the opening of the KCNQ potassium channels, including pain and migraine.
    Type: Application
    Filed: December 9, 2003
    Publication date: July 15, 2004
    Inventors: Kenneth M. Boy, Yong-Jin Wu
  • 1-aryl-2-hydroxyethyl amides as potassium channel openers
    Publication number: 20040122007
    Abstract: The present invention provides novel aryl hydroxyethyl amides and related derivatives having the general Formula I 1
    Type: Application
    Filed: November 21, 2003
    Publication date: June 24, 2004
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Huan He, Alexandre L'Heureux
  • 3-(Pyridinyl-piperazin-1-yl)-phenylethyl amides as potassium channel openers
    Publication number: 20040110765
    Abstract: The present invention provides piperazinyl phenylethyl amides and related derivatives having the general Formula I 1
    Type: Application
    Filed: November 21, 2003
    Publication date: June 10, 2004
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Jie Chen
  • Arylcyclopropylcarboxylic amides as potassium channel openers
    Publication number: 20040110754
    Abstract: The present invention provides novel arylcyclopropylcarboxylic amides and related derivatives having the general Formula I 1
    Type: Application
    Filed: November 21, 2003
    Publication date: June 10, 2004
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Alexandre L'Heureux
  • 3-Heterocyclic benzylamide derivatives as potassium channel openers
    Publication number: 20040106621
    Abstract: The present invention provides novel 3-heterocyclic benzylamides and related derivatives having the general Formula I 1
    Type: Application
    Filed: November 21, 2003
    Publication date: June 3, 2004
    Inventors: Yong-Jin Wu, Alexandre L'Heureux, Huan He
  • Pyridinyl, pyrimidinyl and pyrazinyl amides as potassium channel openers
    Publication number: 20040102449
    Abstract: The present invention provides novel heterocyclic amides and related derivatives having the general Formula I 1
    Type: Application
    Filed: November 21, 2003
    Publication date: May 27, 2004
    Inventors: Yong-Jin Wu, Li-Qiang Sun, Jie Chen, Huan He
  • Novel erythromycin derivatives
    Publication number: 20040067897
    Abstract: The invention relates to novel erythromycin derivatives, particularly ones with novel C-13 R13 substitutents, and to pharmaceutically acceptable salts thereof. The compounds of this invention are useful as antibacterial agents and antiprotozoa agents and for other applications (e.g., anticancer, atherosclerosis, gastric motility reduction, etc.) in mammals, including man, as well as in fish and. The invention also relates to pharmaceutical compositions containing such compounds and to methods of treating bacterial protozoa infections by administering such compounds. The invention also relates to methods of preparing such compounds and to intermediates useful in such preparation.
    Type: Application
    Filed: April 8, 2003
    Publication date: April 8, 2004
    Applicant: Pfizer Inc.
    Inventor: Yong-Jin Wu
  • Pyridopyrimidine derivatives as 5-HT6 antagonists
    Publication number: 20040019064
    Abstract: Novel pyridopyrimidine derivatives which have a binding affinity for the human 5-HT6 receptor and, therefore, are useful in treating disorders responsive to antagonism of the 5-HT6 receptor such as psychosis, schizophrenia, manic depression, depression, neurological disorder, memory disorder, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease and Huntington's chorea.
    Type: Application
    Filed: July 15, 2003
    Publication date: January 29, 2004
    Inventors: Yong-Jin Wu, Shuanghua Hu, Paul M. Scola, Yazhong Huang, Katharine A. Grant-Young
  • Carbamate and carbazate ketolide antibiotics
    Patent number: 6664238
    Abstract: This invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts and solvates thereof wherein X1, X2, R2, R15, R16 and R6 are as defined herein. The compounds of formula 1 are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: December 16, 2003
    Assignee: Pfizer Inc.
    Inventors: Wei-Guo Su, Takushi Kaneko, Yong-Jin Wu
  • 13-Methyl erythromycin derivatives
    Publication number: 20030229031
    Abstract: The invention relates to compounds of the formula 1
    Type: Application
    Filed: May 19, 2003
    Publication date: December 11, 2003
    Applicant: Pfizer Inc.
    Inventors: Yong-Jin Wu, Wei-Guo Su, Takushi Kaneko, Hamish McArthur
  • Cinnamide derivatives as KCNQ potassium channel modulators
    Publication number: 20030166650
    Abstract: There is provided novel cinnamide derivatives of Formula I 1
    Type: Application
    Filed: May 31, 2002
    Publication date: September 4, 2003
    Inventors: Yong-Jin Wu, Li-Quang Sun, Jie Chen, Huan He, Alexandre L'Heureux, Pierre Dextraze, Jean-Paul Daris, Gene G. Kinney, Steven I. Dworetzky, Piyasena Hewawasam
  • 13-Methyl erythromycin derivatives
    Publication number: 20030100518
    Abstract: The invention relates to compounds of the formula 1
    Type: Application
    Filed: May 24, 2000
    Publication date: May 29, 2003
    Inventors: Yong-Jin Wu, Wei-Guo Su, Takushi Kaneko, Hamish Mcarthur
  • Erythromycin a derivatives
    Publication number: 20030100742
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: November 20, 2002
    Publication date: May 29, 2003
    Applicant: Pfizer Inc.
    Inventors: Takushi Kaneko, William Thomas McMillen, Yong-Jin Wu
  • Erythromycin derivatives
    Patent number: 6498146
    Abstract: The invention relates to compounds of the formula 1, 2, and 3 and to pharmaceutically acceptable salts and prodrugs thereof, wherein the groups are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I, methods of using said compounds of formula 1, 2, and 3 the treatment of infections, and methods of preparing said compounds of formula 1, 2, and 3.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: December 24, 2002
    Assignee: Pfizer Inc
    Inventor: Yong-Jin Wu
  • 9a, 11b-dehydro derivatives of 9-oxime-3-keto-6-O- methylerythromycin
    Patent number: 6482801
    Abstract: The invention relates to compounds of the formula and to pharmaceutically acceptable salts thereof, wherein R1 and R2 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1, methods of using said compounds of formula 1 in the treatment of infections, and methods of preparing said compounds of formula 1.
    Type: Grant
    Filed: February 27, 2001
    Date of Patent: November 19, 2002
    Assignee: Pfizer Inc.
    Inventor: Yong-Jin Wu
  • 9-oxime erythromycin derivatives
    Publication number: 20020151507
    Abstract: The invention relates to compounds of formula (I), and to pharmaceutically acceptable salts thereof, wherein R1, R2, R6 and X are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula (I), methods of using said compounds of formula (I) in the treatment of bacterial and protozoa infections, and methods of preparing said compounds of formula (I).
    Type: Application
    Filed: March 26, 2002
    Publication date: October 17, 2002
    Inventor: Yong-Jin Wu
  • Carbamate and carbazate ketolide antibiotics
    Patent number: 6420343
    Abstract: This invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof wherein X1, X2, R2 and R6 are as defined herein. The compounds of formula 1 are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1.
    Type: Grant
    Filed: September 20, 1999
    Date of Patent: July 16, 2002
    Assignee: Pfizer Inc
    Inventors: Wei-Guo Su, Takushi Kaneko, Yong-Jin Wu
  • Tricyclic erythromycin derivatives
    Publication number: 20020077302
    Abstract: The invention relates to compounds of the formula 1 1
    Type: Application
    Filed: April 24, 2000
    Publication date: June 20, 2002
    Inventor: Yong-Jin Wu
  • 9-amino-3-oxo erythromycin derivatives
    Publication number: 20020061857
    Abstract: The invention relates to compounds of the formula 1
    Type: Application
    Filed: April 24, 2000
    Publication date: May 23, 2002
    Inventor: Yong-Jin Wu