Patents by Inventor Yong-Jin Wu

Yong-Jin Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C-4 substituted macrolide antibiotics
    Patent number: 6300316
    Abstract: This invention relates to compounds of the formula and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are potent antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1.
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: October 9, 2001
    Assignee: Pfizer Inc
    Inventors: Katherine E. Brighty, Takushi Kaneko, Robert G. Linde, II, Hiroko Masamune, Paul R. McGuirk, Wei-Guo Su, Yong-Jin Wu, Bingwei V. Yang
  • Tricyclic erythromycin derivatives
    Patent number: 6291656
    Abstract: The invention relates to compounds of the formula I and to pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I, methods of using said compounds of formula I in the treatment of infections, and methods of preparing said compounds of formula I.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: September 18, 2001
    Assignee: Pfizer Inc.
    Inventor: Yong-Jin Wu
  • 9a,11b-dehydro derivatives of 9-oxime-3-keto-6-O- methylerythromycin
    Publication number: 20010016574
    Abstract: The invention relates to compounds of the formula 1
    Type: Application
    Filed: February 27, 2001
    Publication date: August 23, 2001
    Inventor: Yong-Jin Wu
  • Erythromycin derivatives
    Patent number: 6262030
    Abstract: The invention relates to the compounds of the formula 1 and to pharmaceutically acceptable salts thereof, wherein R1, R2, R3, X and Y are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1, methods of using said compounds of formula 1 in the treatment of infections, and methods of preparing said the compounds of formula 1.
    Type: Grant
    Filed: November 2, 1999
    Date of Patent: July 17, 2001
    Assignee: Pfizer Inc.
    Inventors: Yong-Jin Wu, Wei-Guo Su
  • Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-&agr;-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin
    Patent number: 6258785
    Abstract: The invention relates to crystalline 9-E-(O-methyl)oxime of 11,12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-&agr;-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)-1H-imidazol-1-yl)propyl)hydrazono))-3-oxoerythromycin wherein said crystalline compound is as the free base of said compound, the hemihydrate of said compound or the mesylate (methanesufonic acid) salt of said compound. The invention also relates to pharmaceutical compositions containing the foregoing crystalline compound and to methods of treating bacterial and protozoa infections by administering said crystalline compound.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: July 10, 2001
    Assignee: Pfizer Inc.
    Inventors: Wei-Guo Su, Takushi Kaneko, Yong-Jin Wu, Daniel J. Durkin, Kathleen T. Smyth
  • Tricyclic 3-keto derivatives of 6-O-methylerthromycin
    Patent number: 6248719
    Abstract: The present invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts thereof, wherein R1-R7 are as defined herein. The compounds of formula 1 are useful as antibiotic agents. The invention further relates to pharmaceutical compositions and methods of treating bacterial infection using such compounds, and to methods of making the compounds of formula 1.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: June 19, 2001
    Assignee: Pfizer Inc
    Inventor: Yong-Jin Wu
  • Erythromycin derivatives
    Patent number: 6162794
    Abstract: The invention relates to compounds of the formula: ##STR1## and to pharmaceutically acceptable salts thereof, wherein R and Z are as defined herein.The invention also relates to pharmaceutical compositions containing the compounds of formula I, methods of using said compounds of formula I in the treatment of infections and methods of preparing said compounds of formula I.
    Type: Grant
    Filed: July 20, 1999
    Date of Patent: December 19, 2000
    Assignee: Pfizer Inc.
    Inventor: Yong-Jin Wu
  • 9-amino-3-keto erythromycin derivatives
    Patent number: 6159945
    Abstract: The invention relates to compounds of the formula I ##STR1## and to pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and X are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I, methods of using said compounds of formula I in the treatment of infections, and methods of preparing said compounds of formula I.
    Type: Grant
    Filed: October 6, 1999
    Date of Patent: December 12, 2000
    Assignee: Pfizer Inc.
    Inventor: Yong-Jin Wu