Patents by Inventor Yong-Kang Zhang

Yong-Kang Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrolytically-resistant boron-containing therapeutics and methods of use
    Patent number: 7465836
    Abstract: Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
    Type: Grant
    Filed: June 15, 2004
    Date of Patent: December 16, 2008
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Ving Lee, Jacob J. Plattner, Stephen J. Benkovic, Stephen J. Baker, Kirk R. Maples, Carolyn Bellinger-Kawahara, Tsutomu Akama, Yong-Kang Zhang, Rajeshwar Singh, Vittorio A. Sauro
  • ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE
    Publication number: 20080293675
    Abstract: The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
    Type: Application
    Filed: January 9, 2008
    Publication date: November 27, 2008
    Applicant: ANACOR PHARMACEUTCALS INC.
    Inventors: Ving Lee, Stephen Benkovic, Stephen Baker, Kirk Maples, Tsutomu Akama, Yong-Kang Zhang, Rajeshwar Singh, Vittorio Sauro, Chetan Pandit, Zhuoyi Su, Zhixiang Yang
  • Antibiotics containing borinic acid complexes and methods of use
    Patent number: 7390806
    Abstract: The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
    Type: Grant
    Filed: June 14, 2004
    Date of Patent: June 24, 2008
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Ving Lee, Stephen J. Benkovic, Stephen J. Baker, Kirk R. Maples, Tsutomu Akama, Yong-Kang Zhang, Rajeshwar Singh, Vittorio A. Sauro, Chetan Pandit, Zhuoyi Su, Zhixiang Yang
  • BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20070293457
    Abstract: Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.
    Type: Application
    Filed: February 16, 2007
    Publication date: December 20, 2007
    Inventors: Stephen Baker, Virginia Sanders, Tsutomu Akama, Carolyn Bellinger-Kawahara, Yvonne Freund, Kirk Maples, Jacob Plattner, Yong-Kang Zhang, Huchen Zhou, Vincent Hernandez
  • Hydrolytically-Resistant Boron-Containing Therapeutics And Methods Of Use
    Publication number: 20070265226
    Abstract: Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
    Type: Application
    Filed: May 2, 2007
    Publication date: November 15, 2007
    Applicant: Anacor Pharmaceuticals
    Inventors: Ving Lee, Jacob Plattner, Stephen Benkovic, Stephen Baker, Kirk Maples, Carolyn Bellinger-Kawahara, Tsutomu Akama, Yong-Kang Zhang, Rajeshwar Singh, Vittorio Sauro
  • Boron-containing small molecules
    Publication number: 20070155699
    Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
    Type: Application
    Filed: August 16, 2006
    Publication date: July 5, 2007
    Applicant: Anacor Pharmaceuticals
    Inventors: Stephen Baker, Tsutomu Akama, Michael Alley, Steven Benkovic, Michael DiPierro, Vincent Hernandez, Karin Hold, Isaac Kennedy, Igor Likhotvorik, Weimin Mao, Kirk Maples, Jacob Plattner, Fernando Rock, Virginia Sanders, Aaron Stemphoski, George Yiannikouros, Siead Zegar, Yong-Kang Zhang, Huchen Zhou
  • Boron-containing small molecules
    Publication number: 20060234981
    Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
    Type: Application
    Filed: February 16, 2006
    Publication date: October 19, 2006
    Applicant: Anacor Pharmaceuticals
    Inventors: Stephen Baker, Tsutomu Akama, Carolyn Bellinger-Kawahara, Vincent Hernandez, Karin Hold, James Leyden, Kirk Maples, Jacob Plattner, Virginia Sanders, Yong-Kang Zhang
  • Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods
    Publication number: 20060178356
    Abstract: Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
    Type: Application
    Filed: March 22, 2006
    Publication date: August 10, 2006
    Inventors: Bing Wang, Yong-Kang Zhang, Jian Chen, Wei Zhang, Jiangao Song, Ughetta Balzo, Lesley Brown, Sekhar Boddupalli, Steven Bobzin, Sylvain Gilat, Guy Miller
  • Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods
    Publication number: 20050142155
    Abstract: Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
    Type: Application
    Filed: February 10, 2005
    Publication date: June 30, 2005
    Inventors: Bing Wang, Yong-Kang Zhang, Jian Chen, Wei Zhang, Jiangao Song, Ughetta Del Balzo, Lesley Brown, Sekhar Boddupalli, Steven Bobzin, Sylvain Gilat, Guy Miller
  • Alpha-aryl-N-alkylnitrones and pharmaceutical compositions containing the same
    Publication number: 20050124691
    Abstract: Disclosed are novel ?-aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.
    Type: Application
    Filed: March 5, 2004
    Publication date: June 9, 2005
    Inventors: Judith Kelleher, Kirk Maples, Alina Dykman, Yong-Kang Zhang, Allan Wilcox, Julian Levell
  • Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods
    Publication number: 20050113416
    Abstract: Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
    Type: Application
    Filed: December 16, 2004
    Publication date: May 26, 2005
    Inventors: Bing Wang, Yong-Kang Zhang, Jian Chen, Wei Zhang, Jiangao Song, Ughetta Del Balzo, Lesley Brown, Sekhar Boddupalli, Steven Bobzin, Sylvain Gilat, Guy Miller
  • Antibiotics containing borinic acid complexes and methods of use
    Publication number: 20050070503
    Abstract: The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
    Type: Application
    Filed: June 14, 2004
    Publication date: March 31, 2005
    Inventors: Ving Lee, Stephen Benkovic, Stephen Baker, Kirk Maples, Tsutomu Akama, Yong-Kang Zhang, Rajeshwar Singh, Vittorio Sauro, Chetan Pandit, Zhuoyi Su, Zhixiang Yang
  • Hydrolytically-resistant boron-containing therapeutics and methods of use
    Publication number: 20050054644
    Abstract: Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
    Type: Application
    Filed: June 15, 2004
    Publication date: March 10, 2005
    Inventors: Ving Lee, Jacob Plattner, Stephen Benkovic, Stephen Baker, Kirk Maples, Carolyn Bellinger-Kawahara, Tsutomu Akama, Yong-Kang Zhang, Rajeshwar Singh, Vittorio Sauro
  • Alpha-aryl-N-alkylnitrones and pharmaceutical compositions containing the same
    Publication number: 20030087957
    Abstract: Disclosed are novel &agr;-aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.
    Type: Application
    Filed: February 11, 2002
    Publication date: May 8, 2003
    Inventors: Judith A. Kelleher, Kirk R. Maples, Alina Dykman, Yong-Kang Zhang, Allan L. Wilcox, Julian Levell
  • Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods
    Publication number: 20030073712
    Abstract: Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
    Type: Application
    Filed: July 23, 2002
    Publication date: April 17, 2003
    Inventors: Bing Wang, Yong-Kang Zhang, Jian Chen, Wei Zhang, Jiangao Song, Ughetta Del Balzo, Lesley Brown, Sekhar Boddupalli, Steven Bobzin, Sylvain Gilat, Guy Miller
  • Alpha-(4-Ethoxyphenyl)-N-tert-butylnitrone, pharmaceutical compositions and their medical use
    Patent number: 6441032
    Abstract: Disclosed are novel &agr;-aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.
    Type: Grant
    Filed: August 9, 2000
    Date of Patent: August 27, 2002
    Assignee: Centaur Pharmaceuticals, Inc.
    Inventors: Judith A. Kelleher, Kirk R. Maples, Alina Dykman, Yong-Kang Zhang, Allan L. Wilcox, Julian Levell
  • &agr;-aryl-N-alkylnitrones and pharmaceutical compositions containing the same
    Patent number: 6433008
    Abstract: Disclosed are novel aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.
    Type: Grant
    Filed: July 18, 2000
    Date of Patent: August 13, 2002
    Assignee: Centaur Pharmaceuticals, Inc.
    Inventors: Judith A. Kelleher, Kirk R. Maples, Alina Dykman, Yong-Kang Zhang, Allan L. Wilcox, Julian Levell
  • Furan nitrone compounds
    Patent number: 6376540
    Abstract: Disclosed are furan nitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compounds are useful as analytical reagents for detecting free radicals and as therapeutics for treating a wide variety of medical dysfunctions and diseases.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: April 23, 2002
    Assignee: Centaur Pharmaceuticals, Inc.
    Inventors: Judith A. Kelleher, Kirk R. Maples, Lowell David Waterbury, Allan L. Wilcox, Hong Xu, Yong-Kang Zhang
  • Methods for preventing and treating autoimmune and inflammatory disease using thioether furan nitrone compounds
    Patent number: 6310092
    Abstract: Disclosed are methods for preventing the onset of autoimmune or inflammatory diseases in mammals using a pharmaceutical composition containing a pharmaceutically acceptable carrier and an effective amount of a thioether furan nitrone compound.
    Type: Grant
    Filed: February 17, 2000
    Date of Patent: October 30, 2001
    Assignee: Centaur Pharmaceuticals, Inc.
    Inventors: Judith A. Kelleher, Kirk R. Maples, Yong-Kang Zhang
  • Methods for preventing and treating autoimmune and inflammatory diseases using thioether furan nitrone compounds
    Patent number: 6127408
    Abstract: Disclosed are methods for preventing and/or treating autoimmune and inflammatory diseases in mammals using a pharmaceutical composition containing a pharmaceutically acceptable carrier and an effective amount of a thiether furan nitrone compound.
    Type: Grant
    Filed: September 29, 1999
    Date of Patent: October 3, 2000
    Assignee: Centaur Pharmaceuticals, Inc.
    Inventors: Judith A. Kelleher, Kirk R. Maples, Yong-Kang Zhang