Abstract: This disclosure provides methods for treating a condition or disease associated with weight gain that include coadministration of an apelin receptor agonist and a GLP-1 receptor agonist. Methods for increasing total weight loss in the subject relative to weight loss that would be caused by administration of a pre-determined amount of a GLP-1 receptor agonist alone are also provided. In some embodiments, the method is for preserving, or maintaining muscle mass, muscle function, and/or muscle strength in a subject undergoing weight loss therapy.

Abstract: Disclosed is a charging barrel of an infrared dehumidification, crystallization and drying all-in-one machine and a drying machine. The cross section of the charging barrel is in the shape of a polygon, and the side number of the polygon is larger than the side number of a pentagon; an opening is formed in one end, as a feeding end, of the charging barrel; each plate surface forming the polygonal charging barrel comprises a middle plate part, as well as a first closing-up plate part and a second closing-up plate part which are arranged at the two ends of the middle plate part; the first closing-up plate part and the second closing-up plate part form obtuse angles with the middle plate part and are closed up towards the middle; a discharge hole is formed in the side wall of the charging barrel.

Abstract: This disclosure discloses a wireless earphone control method and an electronic device, applied to a wireless earphone which includes: a transceiver, amplifier, control switch and antenna, where a first end of the amplifier is electrically connected to the transceiver, a second end thereof is electrically connected to the antenna, a bypass branch provided with the control switch is disposed between the first end and the second end. The method includes: obtaining a target parameter which includes a signal quality parameter of a target signal on the transceiver; if the signal quality parameter is greater than a signal parameter threshold and a gain of the amplifier is greater than 0, reducing the gain of the amplifier; if the signal quality parameter is greater than the signal parameter threshold and the gain of the amplifier is equal to or less than 0, controlling the control switch to be in a conducted state.

Abstract: In a data processing method, a query distance range is determined based on current position information of a character controlled by a user in a virtual scene. Data for a plurality of non-player characters (NPCs) from a database is determined based on NPCs to be placed in the query distance range. The data includes a plurality of attributes respectively corresponding to each of the plurality of the NPCs. Weights are determined for each of the plurality of NPCs. A first number of NPCs is generated based on a descending order of the weights for each of the plurality of NPCs. The first number of NPCs is a subset of the plurality of NPCs. The generated first number of NPCs are transmitted to a client controlling the player-controlled character to cause the client to display, in the query distance range, virtual images corresponding to the first number of NPCs.

Abstract: Charging and power supply optimization method and apparatus for a charging management system are provided. The method includes: obtaining information about power supply, transformation and distribution of a charging station, capability information of a charging facility, output information of a charging terminal, and charging demand information of an electric vehicle, determining a charging capability, power supply capability and an actual charging capacity of a charging facility system at the charging station, obtaining a model output result based on a pre-trained deep learning time series prediction algorithm model, generating a charging power allocation instruction in combination with an actual charging capacity of a charging facility system at the charging station, and a charging demand of a to-be-charged electric vehicle, and distributing electric energy to each charging facility.

Abstract: Provided is a fused tri-cyclic compound as PDE3/PDE4 dual inhibitor, and a use thereof in the preparation of drugs for PDE3/PDE4 associated diseases, particularly in medicinal functions such as chronic obstructive pulmonary disease (COPD). Provided are specifically a compound of formula (I) and a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of PI3K-? enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with PI3K-? signaling with the compounds and compositions of the disclosure.

Abstract: The present application relates to the technical field of pharmaceutical chemistry, and particularly relates to compounds with ALK inhibitory activity and preparation method and use thereof. The compounds with ALK inhibitory activity provided by the present application are ALK inhibitors for treating diseases responsive to the inhibition of ALK kinase, can be used for treating ALK-positive diseases, such as tumors and cancers, and have broad application prospects.

Abstract: A display panel includes a substrate, a plurality of data lines, at least one circle of barrier wall structure, and a connector. The substrate includes a display area, and a peripheral area which surrounds the display area and includes a fan-out area. The plurality of data lines are located on one side of the substrate and in the display area, extending from the display area to the fan-out area. The at least one circle of barrier wall structure surrounds the display area, and at least a part of the at least one circle of barrier wall structure is located in the fan-out area. The connector is located between the plurality of data lines and the barrier wall structure, and one end, away from the substrate, of the connector extends into the barrier wall structure to fasten the barrier wall structure.

Abstract: A gear-hydraulic-rhombic pyramid integrated multi-mode hybrid transmission device includes an input assembly, a hydraulic transmission mechanism, a front planetary gear mechanism, a rhombic pyramid-type continuously variable transmission mechanism, a rear planetary gear mechanism, an output assembly, a clutch assembly, and a brake assembly. The clutch assembly connects an output end of the input assembly to an input end of the hydraulic transmission mechanism and an input end of the front planetary gear mechanism. The clutch assembly connects an output end of the hydraulic transmission mechanism to the front planetary gear mechanism and the rear planetary gear mechanism. The clutch assembly connects the front planetary gear mechanism, the rhombic pyramid-type continuously variable transmission mechanism, the rear planetary gear mechanism, and the output assembly in sequence. The clutch assembly and the brake assembly provide a continuous transmission ratio between the input assembly and the output assembly.

Abstract: A Lactobacillus paracasei and uses thereof. The Lactobacillus paracasei has a deposit number of CGMCC No. 14813. The Lactobacillus paracasei can be used for increasing the amount of an organic acid in a raw material. The Lactobacillus paracasei can be used for fermenting the raw material, where the raw material can be selected from at least one of fruits, which can increase the content of the organic acid in a fermented product.

Abstract: The present disclosure belongs to the technical field of membrane separation, and discloses a preparation method of a Ti3C2Tx MXene quantum dot (MQD)-modified polyamide (PA) reverse osmosis (RO) membrane. The preparation method includes the following steps: subjecting a Ti3C2Tx MXene material to liquid nitrogen intercalation and interlayer expansion to obtain a Ti3C2Tx MQD nanomaterial; preparing an aqueous phase solution with the Ti3C2Tx MQD nanomaterial and an organic phase solution; soaking an ultrafiltration (UF) base membrane in the aqueous phase solution , and removing the aqueous phase solution on a surface of the UF base membrane through blow-drying; soaking the second UF base membrane in the organic phase solution to allow interfacial polymerization to form an active layer; and allowing a composite membrane obtained after the interfacial polymerization to stand, followed by a heat treatment to further promote the interfacial polymerization.

Abstract: A code execution method and a data processing device and system are provided. The method includes storing, through a data processing device, multiple executable files corresponding to multiple functions and multiple call information obtained by parsing a target model through a compile into a main memory and running, through the data processing device, the target model. The running, through the data processing device, the target model includes the following: loading an executable file from the main memory into an application code area of a local memory based on a running sequence of a plurality of functions and loading corresponding call information into a stack area of the local memory; and running the executable file in the application code area based on the call information in the stack area and transferring a running result from the local memory to the main memory after the running is completed.

Abstract: A registration system for robot-oriented augmented reality teaching system, comprising: a physical robot unit, a registration unit, a virtual robot generation unit and a computer; the physical robot unit comprising a physical robot, a physical robot controller and a robot point-to-point intermittent movement control program; the physical robot provided thereon with a physical robot base coordinate system; the physical robot controller connected with the physical robot and the computer respectively; the robot point-to-point intermittent movement control program installed in the computer; the registration unit comprising a registration marker, a camera and a conversion calculation unit; the registration marker arranged on the physical robot body; the camera fixed in a physical environment except the physical robot; the camera connected with the computer, and the conversion calculation unit arranged in the computer; the virtual robot generation unit arranged in the computer and used for generating a virtual robo

Abstract: The present invention discloses a compound fluorine-free foam extinguishing agent and a preparation method therefor, comprising components of the following parts by weight: 6-8 parts of alkyl glycoside, 10-14 parts of polysiloxane quaternary ammonium salt, 0.5-1 part of silicon dioxide and 60-65 parts of water. The compound fluorine-free foam extinguishing agent prepared by the present invention has a high stability, a high expansion, an obvious fire extinguishing effect and a higher environment-friendliness. The polysiloxane quaternary ammonium salt contains hydrophobic polysiloxane long chains, has a high temperature resistance, and collaborates with the alkyl glycoside to be adsorbed on the surface of silicon dioxide particles, which improves the stability of the silicon dioxide in a solution and reduces the surface tension of the solution.

Abstract: The disclosure provides a parking space detection method and device, a vehicle, and a storage medium.

Abstract: An object management method includes: obtaining position information of a first object added in a scene; determining, from an object management tree corresponding to the scene, a first node according to the position information of the first object; dividing, in response to that a quantity of objects contained in the area corresponding to the first node is greater than an upper limit after the first object is added to the area corresponding to the first node, the area corresponding to the first node into n sub-areas according to position information of objects contained in the area corresponding to the first node; and configuring, in the object management tree, n nodes in one-to-one correspondence with the n sub-areas.

Abstract: Implementations of the present disclosure provide a service processing method, device, and system associated with unified resource locator (URL)-based two-dimensional (code). In an implementation, a URL is received from a first service institution. The URL is obtained by a mobile device from scanning a 2D code provided by a service provider and sent to the first service institution. The URL is then parsed to identify one or more data elements including a service network identifier, a service institution identifier, and a payload including a service object identifier. The one or more data elements is sent to the second service institution based on the service institution identifier. Service information associated with the service object is received from the second service institution based on the service object identifier, and the service information is sent to the first service institution for presenting on the mobile device.

Abstract: The present invention relates to a robot teaching system based on image segmentation and surface electromyography and robot teaching method thereof, comprising a RGB-D camera, a surface electromyography sensor, a robot and a computer, wherein the RGB-D camera collects video information of robot teaching scenes and sends to the computer; the surface electromyography sensor acquires surface electromyography signals and inertial acceleration signals of the robot teacher, and sends to the computer; the computer recognizes a articulated arm and a human joint, detects a contact position between the articulated arm and the human joint, and further calculates strength and direction of forces rendered from a human contact position after the human joint contacts the articulated arm, and sends a signal controlling the contacted articulated arm to move along with such a strength and direction of forces and robot teaching is done.

Abstract: A registration system for robot-oriented augmented reality teaching system, comprising: a physical robot unit, a registration unit, a virtual robot generation unit and a computer; the physical robot unit comprising a physical robot, a physical robot controller and a robot point-to-point intermittent movement control program; the physical robot provided thereon with a physical robot base coordinate system; the physical robot controller connected with the physical robot and the computer respectively; the robot point-to-point intermittent movement control program installed in the computer; the registration unit comprising a registration marker, a camera and a conversion calculation unit; the registration marker arranged on the physical robot body; the camera fixed in a physical environment except the physical robot; the camera connected with the computer, and the conversion calculation unit arranged in the computer; the virtual robot generation unit arranged in the computer and used for generating a virtual robo