Abstract: Marinopyrrole derivatives and methods for their synthesis and use are described herein. Novel cyclic and symmetric marinopyrroles with triazole substituents having antibacterial activity against resistant bacterial strains, such as MRSA are introduced. Also provided are methods of using the compounds for treating or preventing cancer and/or microbial infections.

Abstract: Embodiments of the present disclosure relate to non-sequential document comparison. A first plurality of segments in a first document and a second plurality of segments in a second document are obtained. In response to a first segment from the first plurality of segments being associated with a second segment from the second plurality of segments, a third segment from the first plurality of segments is associated with a fourth segment from the second plurality of segments.

Abstract: The disclosed flow cytometer includes a wavelength division multiplexer (WDM). The WDM includes an extended light source providing light that forms an object, a collimating optical element that captures light from the extended light source and projects a magnified image of the object as a first light beam, and a first focusing optical element configured to focus the first light beam to a size smaller than the object of the extended light source to a first semiconductor detector. The disclosed flow cytometer further includes a composite microscope objective to direct light emitted by a particle in a flow channel in a viewing zone of the composite microscope to the extended light source, a fluidic system and a peristaltic pump configured to supply liquid sheath and liquid sample to the flow channel, and a laser diode system to illuminate the particle in the flow channel.

Abstract: The disclosed flow cytometer includes a wavelength division multiplexer (WDM). The WDM includes an extended light source providing light that forms an object, a collimating optical element that captures light from the extended light source and projects a magnified image of the object as a first light beam, and a first focusing optical element configured to focus the first light beam to a size smaller than the object of the extended light source to a first semiconductor detector. The disclosed flow cytometer further includes a composite microscope objective to direct light emitted by a particle in a flow channel in a viewing zone of the composite microscope to the extended light source, a fluidic system and a peristaltic pump configured to supply liquid sheath and liquid sample to the flow channel, and a laser diode system to illuminate the particle in the flow channel.

Abstract: The present invention relates to the petroleum drilling fluid field, and discloses a modified silicon dioxide nano-particle comprising a modifying polymer chain composed of structural units provided by one or more of monomers represented by the following formula (1) and one or more of monomers represented by the following formula (2). The present invention provides a method for preparing modified silicon dioxide nano-particles and a drilling fluid suitable for shale gas wells containing the modified silicon dioxide nano-particles as a plugging agent. When the modified silicon dioxide nano-particles provided in the present invention are used as a plugging agent in a drilling fluid, they will not agglomerate into large-size particles, and can achieve a good plugging effect.

Abstract: The disclosed flow cytometer includes a wavelength division multiplexer (WDM). The WDM includes an extended light source providing light that forms an object, a collimating optical element that captures light from the extended light source and projects a magnified image of the object as a first light beam, and a first focusing optical element configured to focus the first light beam to a size smaller than the object of the extended light source to a first semiconductor detector. The disclosed flow cytometer further includes a composite microscope objective to direct light emitted by a particle in a flow channel in a viewing zone of the composite microscope to the extended light source, a fluidic system and a peristaltic pump configured to supply liquid sheath and liquid sample to the flow channel, and a laser diode system to illuminate the particle in the flow channel.

Abstract: The present invention provides a fault prediction and condition-based repair method of an urban rail train bogie. An optimum service life distribution model of a framework, a spring device, a connecting device, a wheel set and axle box, a driving mechanism, and a basic brake device of a bogie is determined by adopting a method based on survival analysis; a reliability characteristic function of each subsystem is obtained; then, a failure rate of each subsystem of the bogie is calculated by adopting a neural network model optimized by an evolutionary algorithm; and finally, proportional risk modelling is conducted by taking the failure rate and safe operation days of each subsystem of the bogie as concomitant variables; and on the basis of cost optimization, thresholds and control limits for condition-based repair of a bogie system are obtained.

Abstract: Symmetrical marinopyrrole derivatives are disclosed herein, as is a synthetic route for producing these compounds. Also disclosed are methods of using symmetrical marinopyrrole derivatives to treat bacterial pathogens, like MRSE, MSSA and MRSA.

Abstract: A system and method for providing directional information to a user using existing infrastructure elements (150) is disclosed. The method comprising determining a route of infrastructure elements (150) between a current location and a remote location, wherein the current location is associated a first element in the route and the last element in the route being closest to the remote location, wherein each of the elements in the route are identified by at least one of: a physical identification and a data identification, and providing a visual indication, progressively, to each of the infrastructure elements in the route at a predetermined time and for a determined period, wherein the progressive display of the visual indication provides for direction control information.

Abstract: The invention discloses a complex network-based high speed train system safety evaluation method. The method includes steps as follows: (1) constructing a network model of a physical structure of a high speed train system, and constructing a functional attribute degree of a node based on the network model; (2) extracting a functional attribute degree, a failure rate and mean time between failures of a component as an input quantity, conducting an SVM training using LIBSVM software; (3) conducting a weighted kNN-SVM judgment: an unclassifiable sample point is judged so as to obtain a safety level of the high speed train system. For a high speed train system having a complicated physical structure and operation conditions, the method can evaluate the degree of influences on system safety when a state of a component in the system changes. The experimental result shows that the algorithm has high accuracy and good practicality.

Abstract: In an approach for visual liveness detection, a video-audio signal related to a speaker speaking a text is obtained. The video-audio signal is split into a video signal which records images of the speaker and an audio signal which records a speech spoken by the speaker. Then a first sequence indicating visual mouth openness is obtained from the video signal, and a second sequence indicating acoustic mouth openness is obtained based on the text and the audio signal. Synchrony between the first and second sequences is measured, and the liveness of the speaker is determined based on the synchrony.

Abstract: A method and system for achieving emotional text to speech. The method includes: receiving text data; generating emotion tag for the text data by a rhythm piece; and achieving TTS to the text data corresponding to the emotion tag, where the emotion tags are expressed as a set of emotion vectors; where each emotion vector includes a plurality of emotion scores given based on a plurality of emotion categories. A system for the same includes: a text data receiving module; an emotion tag generating module; and a TTS module for achieving TTS, wherein the emotion tag is expressed as a set of emotion vectors; and wherein emotion vector includes a plurality of emotion scores given based on a plurality of emotion categories.

Abstract: A control system is provided for performing staging control of a multi-stage combustor of a gas turbine engine. The fuel is fed to the combustor by a fuel supply system comprising: a plurality of fuel manifolds distributing fuel to respective stages of the combustor, a fuel metering valve operable to control the rate at which fuel passes to the fuel manifolds, and an actuating arrangement which splits the fuel flow from the fuel metering valve between the fuel manifolds. The control system includes a fuel pressure sensor arrangement which senses the fuel pressure at entry to the actuating arrangement, and/or in one or more of the fuel manifolds. The control system further includes a controller which repeatedly: calculates a fuel split between the fuel manifolds based on the sensed fuel pressure(s), and issues a command signal to the actuating arrangement to implement the calculated fuel pressure-based fuel split.

Abstract: Marinopyrrole derivatives and methods for their synthesis and use are described herein. Novel cyclic and symmetric marinopyrroles with triazole substituents having antibacterial activity against resistant bacterial strains, such as MRSA are introduced. Also provided are methods of using the compounds for treating or preventing cancer and/or microbial infections.

Abstract: A method and system for achieving emotional text to speech. The method includes: receiving text data; generating emotion tag for the text data by a rhythm piece; and achieving TTS to the text data corresponding to the emotion tag, where the emotion tags are expressed as a set of emotion vectors; where each emotion vector includes a plurality of emotion scores given based on a plurality of emotion categories. A system for the same includes: a text data receiving module; an emotion tag generating module; and a TTS module for achieving TTS, wherein the emotion tag is expressed as a set of emotion vectors; and wherein emotion vector includes a plurality of emotion scores given based on a plurality of emotion categories.

Abstract: In an approach for visual liveness detection, a video-audio signal related to a speaker speaking a text is obtained. The video-audio signal is split into a video signal which records images of the speaker and an audio signal which records a speech spoken by the speaker. Then a first sequence indicating visual mouth openness is obtained from the video signal, and a second sequence indicating acoustic mouth openness is obtained based on the text and the audio signal. Synchrony between the first and second sequences is measured, and the liveness of the speaker is determined based on the synchrony.

Abstract: The disclosed flow cytometer includes a wavelength division multiplexer (WDM). The WDM includes an extended light source providing light that forms an object, a collimating optical element that captures light from the extended light source and projects a magnified image of the object as a first light beam, and a first focusing optical element configured to focus the first light beam to a size smaller than the object of the extended light source to a first semiconductor detector. The disclosed flow cytometer further includes a composite microscope objective to direct light emitted by a particle in a flow channel in a viewing zone of the composite microscope to the extended light source, a fluidic system and a peristaltic pump configured to supply liquid sheath and liquid sample to the flow channel, and a laser diode system to illuminate the particle in the flow channel.

Abstract: The invention discloses a complex network-based high speed train system safety evaluation method. The method includes steps as follows: (1) constructing a network model of a physical structure of a high speed train system, and constructing a functional attribute degree of a node based on the network model; (2) extracting a functional attribute degree, a failure rate and mean time between failures of a component as an input quantity, conducting an SVM training using LIBSVM software; (3) conducting a weighted kNN-SVM judgment: an unclassifiable sample point is judged so as to obtain a safety level of the high speed train system. For a high speed train system having a complicated physical structure and operation conditions, the method can evaluate the degree of influences on system safety when a state of a component in the system changes. The experimental result shows that the algorithm has high accuracy and good practicality.

Abstract: The present invention relates to voice processing and provides a method and system for correcting a text. The method comprising: determining a target text unit to be corrected in a text; receiving a reference voice segment input by the user for the target text unit; determining a reference text unit whose pronunciation is similar to a word in the target text unit based on the reference voice segment; and correcting the word in the target text unit in the text by the reference text unit. The present invention enables the user to easily correct errors in the text vocally.

Abstract: The present invention provides systems and methods for analyzing the excitation spectra of fluorescent particles in a flowing stream. The system uses a white light laser and color separation optics to provide a spatially-distributed, continuous color-spectrum excitation light system that is used to illuminate a region of a flowing stream. A particle that passes through the detection region traverses the full dispersed spectrum of excitation light, and the fluorescence emissions from the particle are continuously measured as it passes through the detection region. The measured fluorescence emissions at each wavelength of excitation light, which changes through full spectrum of the excitation light as the particle passes through the detection region, provides the excitation spectrum of the particle.