Patents by Inventor Yong Tu

Yong Tu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for synthesis of 2-methyl-2-hydroxyheptane and 2-methyl 2-alkoxyheptanes
    Patent number: 11926577
    Abstract: The present disclosure pertains to a new synthetic method for the preparation of 2-methyl-2-hydroxyheptane and 2-methyl-2-alkoxyheptanes, which are valuable commodities for use in flavors, fragrances and various personal care products, such as cosmetics.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: March 12, 2024
    Assignee: P2 SCIENCE, INC.
    Inventors: Patrick Foley, Yonghua Yang, Yong Tu
  • SYNTHETIC METHODS FOR MAKING CARBOXYLIC ACIDS, ESTERS AND LACTONES
    Publication number: 20230202996
    Abstract: The present disclosure pertains to a new synthetic method for the preparation of 3,6-dimethylhexahydrobenzofuran-2-one, a derivative of mint lactone, and an important organoleptic compound which finds use in the flavor and fragrance industries. Applicants' novel synthetic route is also applicable to other alkene compounds.
    Type: Application
    Filed: December 22, 2022
    Publication date: June 29, 2023
    Inventors: Yong TU, Yonghua YANG, Patrick FOLEY, Ted ANASTASIOU, Tania SALAM, Alex MATTESON, Vivek BULBULE
  • NEW METHOD FOR SYNTHESIS OF 2-METHYL-2-HYDROXYHEPTANE AND 2-METHYL 2-ALKOXYHEPTANES
    Publication number: 20230065920
    Abstract: The present disclosure pertains to a new synthetic method for the preparation of 2-methyl-2-hydroxyheptane and 2-methyl-2-alkoxyheptanes, which are valuable commodities for use in flavors, fragrances and various personal care products, such as cosmetics.
    Type: Application
    Filed: October 8, 2021
    Publication date: March 2, 2023
    Inventors: Patrick FOLEY, Yonghua YANG, Yong TU
  • Hepatitis C virus inhibitors
    Patent number: 10617675
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: April 14, 2020
    Assignee: Bristol-Myers Squibb Company
    Inventors: David B. Frennesson, Piyasena Hewawasam, Omar D. Lopez, Van N. Nguyen, Mark G. Saulnier, Yong Tu, Alan Xiangdong Wang, Gan Wang, Ningning Xu, Roshan Yadavrao Nimje, Hasibur Rahaman, Samayamunthula Venkata Satya Arun Kumar Gupta, Nicholas A. Meanwell, Makonen Belema
  • Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
    Patent number: 10351546
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: July 16, 2019
    Assignee: ViiV HEALTHCARE UK (NO. 5) LIMITED
    Inventors: Kyle J. Eastman, John F. Kadow, B. Narasimhulu Naidu, Kyle E. Parcella, Manoj Patel, Prasanna Sivaprakasam, Yong Tu
  • Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
    Patent number: 10106504
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: October 23, 2018
    Assignee: ViiV HEALTHCARE UK (NO.5) LIMITED
    Inventors: John F. Kadow, B. Narasimhulu Naidu, Yong Tu
  • PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20180230124
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV.
    Type: Application
    Filed: August 10, 2016
    Publication date: August 16, 2018
    Inventors: Kyle J. EASTMAN, John F. KADOW, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Manoj PATEL, Prasanna SIVAPRAKASAM, Yong TU
  • PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20180222864
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Application
    Filed: August 18, 2016
    Publication date: August 9, 2018
    Inventors: John F. KADOW, B. Narasimhulu NAIDU, Yong TU
  • HEPATITIS C VIRUS INHIBITORS
    Publication number: 20180221342
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Application
    Filed: July 27, 2016
    Publication date: August 9, 2018
    Inventors: David B. Frennesson, Piyasena Hewawasam, Omar D. Lopez, Van N. Nguyen, Mark G. Saulnier, Yong Tu, Alan Xiangdong Wang, Gan Wang, Ningning Xu, Roshan Yadavrao Nimje, Hasibur Rahaman, Samayamunthula Venkata Satya Arun Kumar Gupta, Nicholas A. Meanwell, Makonen Belema
  • PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20180147196
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Application
    Filed: July 7, 2016
    Publication date: May 31, 2018
    Inventors: Kyle J. EASTMAN, John F. KADOW, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Manoj PATEL, Yong TU
  • Blade device for a mixing propeller and the application thereof
    Patent number: 9776148
    Abstract: A blade device for a mixing propeller has a rocking shaft and a plurality of blade units. The blade unit is made of a flexible material and is installed on the rocking shaft via a fixing groove. The blade unit includes a horizontal propelling flexible blade and a vertical uplifting flexible blade. The fixing groove has a horizontal section and a vertical section. One end of the horizontal propelling flexible blade is inserted in the vertical section of the fixing groove while the other end of which is kept free so that it can swing back and forth. One end of the vertical uplifting flexible blade is inserted in the horizontal section of the fixing groove while the other end of which is kept free so that it can swing back and forth.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: October 3, 2017
    Assignee: JIANGSU PROVINCIAL ACADEMY OF ENVIRONMENTAL SCIENCE
    Inventors: Ming Xu, Weijing Liu, Yong Tu, Haisuo Wu
  • Hepatitis C virus inhibitors
    Patent number: 9770439
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: September 26, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Piyasena Hewawasam, Omar D. Lopez, Yong Tu, Alan Xiangdong Wang, Ningning Xu, John F. Kadow, Nicholas A. Meanwell, Samayamunthula Venkata Satya Arun Kumar Gupta, Indasi J. Gopi Kumar, Suresh Kumar Ponugupati, Makonen Belema
  • Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus
    Patent number: 9717712
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: August 1, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Alan Xiangdong Wang, Omar D. Lopez, Yong Tu, Makonen Belema
  • HEPATITIS C VIRUS INHIBITORS
    Publication number: 20160199355
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Application
    Filed: March 11, 2016
    Publication date: July 14, 2016
    Inventors: PIYASENA HEWAWASAM, JOHN F. KADOW, OMAR D. LOPEZ, NICHOLAS A. MEANWELL, YONG TU, ALAN XIANGDONG WANG, NINGNING XU, SAMAYAMUNTHULA VENKATA SATYA ARUN KUMAR GUPTA, POTHUKANURI SRINIVASU, INDASI GOPI KUMAR, PONUGUPATI SURESH KUMAR, MAKONEN BELEMA, ROBERT A. FRIDELL, MIN GAO, JULIE A. LEMM, DONALD R. O'BOYLE, II, JIN-HUA SUN, CHUNFU WANG, YING-KAI WANG
  • Combinations Comprising Tricyclohexadecahexaene Derivatives for Use in the Treatment of Hepatitis C Virus
    Publication number: 20160166547
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Application
    Filed: July 15, 2014
    Publication date: June 16, 2016
    Inventors: Alan Xiangdong Wang, Omar D. Lopez, Yong Tu, Makonen Belema
  • Combinations of Hepatitis C Virus Inhibitors
    Publication number: 20160158200
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Application
    Filed: July 9, 2013
    Publication date: June 9, 2016
    Inventors: Piyasena Hewawasam, Omar D. Lopez, Yong Tu, Alan Xiangdong Wang, Ningning Xu, John F. Kadow, Nicholas A. Meanwell, Samayamunthula Venkata Satya Arun Kumar Gupta, Indasi J. Gopi Kumar, Suresh Kumar Punugupati, Makonen Belema
  • Hepatitis C virus inhibitors
    Patent number: 9326973
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: May 3, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Piyasena Hewawasam, John F. Kadow, Omar D. Lopez, Nicholas A. Meanwell, Yong Tu, Alan Xiangdong Wang, Ningning Xu, Samayamunthula Venkata Satya Arun Kumar Gupta, Pothukanuri Srinivasu, Indasi Gopi Kumar, Ponugupati Suresh Kumar, Makonen Belema, Robert A. Fridell, Min Gao, Julie A. Lemm, Donald R. O'Boyle, II, Jin-Hua Sun, Chunfu Wang, Ying-Kai Wang
  • Blade Device for the Mixing Propeller and the Application Thereof
    Publication number: 20160067658
    Abstract: The present invention discloses a blade device for the mixing propeller comprises a rocking shaft and a plurality of blade units; the said blade unit is made of flexible material and is installed on the rocking shaft via the fixing groove; the said blade unit consists of a horizontal propelling flexible blade and a vertical uplifting flexible blade whereas the said fixing groove consists of a horizontal section and a vertical section; one end of the said horizontal propelling flexible blade is inserted in the vertical section of the fixing groove while the other end of which is kept free so that it can swing back and forth; one end of the said vertical uplifting flexible blade is inserted in the horizontal section of the fixing groove while the other end of which is kept free so that it can swing back and forth.
    Type: Application
    Filed: January 26, 2015
    Publication date: March 10, 2016
    Inventors: Ming XU, Weijing LIU, Yong TU, Haisuo WU
  • Hepatitis C Virus Inhibitors
    Publication number: 20150297568
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Application
    Filed: June 29, 2015
    Publication date: October 22, 2015
    Inventors: Piyasena Hewawasam, Omar D. Lopez, Yong Tu, Alan Xiangdong Wang, Ningning Xu, John F. Kadow, Nicholas A. Meanwell, Samayamunthula Venkata Satya Arun Kumar Gupta, Indasi J. Gopi Kumar, Suresh Kumar Ponugupati, Makonen Belema
  • Hepatitis C Virus Inhibitors
    Publication number: 20150023913
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Application
    Filed: July 2, 2013
    Publication date: January 22, 2015
    Inventors: Piyasena Hewawasam, Omar D. Lopez, Yong Tu, Alan Xiangdong Wang, Ningning Xu, John F. Kadow, Nicholas A. Meanwell, Samayamuthula Venkata Satya Arun Kumar Gupta, Indasi J. Gopi Kumar, Suresh Kumar Ponugupati, Makonen Belema