Patents by Inventor Yong Tu

Yong Tu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis C Virus Inhibitors
    Publication number: 20150023913
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
    Type: Application
    Filed: July 2, 2013
    Publication date: January 22, 2015
    Inventors: Piyasena Hewawasam, Omar D. Lopez, Yong Tu, Alan Xiangdong Wang, Ningning Xu, John F. Kadow, Nicholas A. Meanwell, Samayamuthula Venkata Satya Arun Kumar Gupta, Indasi J. Gopi Kumar, Suresh Kumar Ponugupati, Makonen Belema
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20120115847
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: January 19, 2012
    Publication date: May 10, 2012
    Inventors: Piyasena Hewawasam, Yong Tu, John A. Bender, Zhong Yang
  • Compounds for the treatment of Hepatitis C
    Patent number: 8129367
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: November 18, 2008
    Date of Patent: March 6, 2012
    Assignee: Bristol-Myers Squibb Company
    Inventors: Piyasena Hewawasam, Yong Tu, John A. Bender, Zhong Yang
  • Compounds for the treatment of Hepatitis C
    Patent number: 7547690
    Abstract: The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: June 16, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert G. Gentles, Xiaofan Zheng, Min Ding, Yong Tu, Ying Han, Piyasena Hewawasam, John F. Kadow, John A. Bender, Kap-Sun Yeung, Katharine A. Grant-Young, Thomas W. Hudyma
  • Compounds for the treatment of hepatitis C
    Patent number: 7541353
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: June 2, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert G. Gentles, Xiaofan Zheng, Min Ding, Yong Tu, Ying Han, Piyasena Hewawasam, John F. Kadow, John A. Bender, Kap-Sun Yeung, Katharine A. Grant-Young, Thomas W. Hudyma
  • Compounds for the treatment of Hepatitis C
    Patent number: 7538102
    Abstract: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: May 26, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kap-Sun Yeung, John A. Bender, Robert G. Gentles, Zhong Yang, Min Ding, Yong Tu, Piyasena Hewawasam, Ying Han, John F. Kadow
  • Compounds for the treatment of hepatitis C
    Patent number: 7538103
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: May 26, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Piyasena Hewawasam, Yong Tu
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20090130057
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: November 18, 2008
    Publication date: May 21, 2009
    Inventors: Piyasena Hewawasam, Yong Tu, John A. Bender, Zhong Yang
  • Compounds for the treatment of hepatitis C
    Patent number: 7521444
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: April 21, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: John A. Bender, Robert G. Gentles, Ying Han, Yong Tu, Zhong Yang, Kap-Sun Yeung, Katharine A. Grant-Young
  • Indolobenzazepine HCV NS5B inhibitors
    Patent number: 7473688
    Abstract: The invention encompasses compounds and salts of Formulas I, II, III, and IV as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: January 6, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Carl P. Bergstrom, John A. Bender, Robert G. Gentles, Piyasena Hewawasam, Thomas W. Hudyma, John F. Kadow, Scott W. Martin, Alicia Regueiro-Ren, Kap-Sun Yeung, Yong Tu, Katharine A. Grant-Young, Xiaofan Zheng
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20080226590
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: March 11, 2008
    Publication date: September 18, 2008
    Inventors: John A. Bender, Robert G. Gentles, Ying Han, Yong Tu, Zhong Yang, Kap-Sun Yeung, Katharine A. Grant-Young
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20080226591
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: March 11, 2008
    Publication date: September 18, 2008
    Inventors: Robert G. Gentles, Xiaofan Zheng, Min Ding, Yong Tu, Ying Han, Piyasena Hewawasam, John F. Kadow, John A. Bender, Kap-Sun Yeung, Katharine A. Grant-Young, Thomas W. Hudyma
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20080226592
    Abstract: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: March 11, 2008
    Publication date: September 18, 2008
    Inventors: Kap-Sun Yeung, John A. Bender, Robert G. Gentles, Zhong Yang, Min Ding, Yong Tu, Piyasena Hewawasam, Ying Han, John F. Kadow
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20080226593
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: March 11, 2008
    Publication date: September 18, 2008
    Inventors: Piyasena Hewawasam, Yong Tu
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20080227769
    Abstract: The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: February 28, 2008
    Publication date: September 18, 2008
    Inventors: Robert G. Gentles, Xiaofan Zheng, Min Ding, Yong Tu, Ying Han, Piyasena Hewawasam, John F. Kadow, John A. Bender, Kap-Sun Yeung, Katharine A. Grant-Young, Thomas W. Hudyma
  • Hepatitis C virus inhibitors
    Patent number: 7309708
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R?, B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: December 18, 2007
    Assignee: Birstol-Myers Squibb Company
    Inventors: Yong Tu, Paul Michael Scola, Andrew Charles Good, Jeffrey Allen Campbell
  • Indolobenzazepine HCV NS5B inhibitors
    Publication number: 20070078122
    Abstract: The invention encompasses compounds and salts of Formulas I, II, III, and IV as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: September 6, 2006
    Publication date: April 5, 2007
    Inventors: Carl Bergstrom, John Bender, Robert Gentles, Piyasena Hewawasam, Thomas Hudyma, John Kadow, Scott Martin, Alicia Regueiro-Ren, Kap-Sun Yeung, Yong Tu, Katharine Grant-Young, Xiaofan Zheng
  • Hepatitis C virus inhibitors
    Publication number: 20050143316
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R?, B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: November 18, 2004
    Publication date: June 30, 2005
    Inventors: Yong Tu, Paul Scola, Andrew Good, Jeffrey Campbell
  • Substituted cycloalkyl P1? hepatitis C virus inhibitors
    Patent number: 6878722
    Abstract: The present invention relates to tripeptide compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. In particular, the present invention provides novel tripeptide analogs, pharmaceutical compositions containing such analogs and methods for using these analogs in the treatment of HCV infection.
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: April 12, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jeffrey Allen Campbell, Stanley D'Andrea, Andrew Good, Jianqing Li, Fiona Mcphee, Amy Ripka, Paul Michael Scola, Yong Tu
  • Substituted cycloalkyl P1' hepatitis C virus inhibitors
    Publication number: 20040077551
    Abstract: The present invention relates to tripeptide compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. In particular, the present invention provides novel tripeptide analogs, pharmaceutical compositions containing such analogs and methods for using these analogs in the treatment of HCV infection.
    Type: Application
    Filed: May 20, 2003
    Publication date: April 22, 2004
    Inventors: Jeffrey Allen Campbell, Stanley D'Andrea, Andrew Good, Jianqing Li, Fiona Mcphee, Amy Ripka, Paul Michael Scola, Yong Tu