Abstract: From a set of point data, a set of scattered rays is constructed. From the set of scattered rays, a set of ray slopes is computed. The set of ray slopes is mapped to a corresponding set of trigonometric functions. Using an optimization method, a parameter of the set of trigonometric functions is selected. Using an inverse of the set trigonometric functions, a vehicle mass corresponding to the set of point data is computed. Based on the vehicle mass, a threshold braking distance of a collision avoidance system of the vehicle is adjusted, the threshold braking distance comprising a distance from an object predicted to collide with the vehicle. By braking the vehicle at least the threshold braking distance from the object, a predicted collision between the vehicle and the object is avoided.

Abstract: A 4D quantitative and intelligent diagnosis method for spatio-temporal evolution of oil-gas reservoir damage types and extent includes: determining a characteristic parameter characterizing reservoir damage by each of a plurality of factors based on a spatio-temporal evolution simulation equation of reservoir damage by each of the plurality of factors; and determining an effective characteristic parameter characterizing the damage extent of the reservoir based on the characteristic parameter characterizing reservoir damage by each of the plurality of factors. The method quantitatively simulate the characteristic parameters of reservoir damage caused by the various factors and a total characteristic parameter of the reservoir damage.

Abstract: The present invention relates to processes for the synthetic preparation of c-Met inhibitors of Formula I, or pharmaceutically acceptable salts thereof. The present invention further relates to processes for the synthetic preparation of the c-Met inhibitor, Compound 1, or a pharmaceutically acceptable salt thereof. The present invention also relates to processes for the synthetic preparation of Compound 1.hemifumarate. The invention further relates to large scale processes for the synthetic preparation of the c-Met inhibitor, Compound 1 and Compound 1.hemifumarate.

Abstract: The disclosure provides a method for preparing a hollow fiber membrane by melt spinning-stretching and selective swelling, including: preparing a nascent hollow fiber by melt spinning in an inert gas protective atmosphere by using an amphiphilic block copolymer as a film forming material, and stretching the nascent hollow fiber in the cooling process, a stretch rate being controlled at 200-540 mm/min, and a stretch ratio being controlled at 150-600%; immersing the obtained hollow fiber in a swelling solvent, and treating the hollow fiber in a water bath at 65° C. for 1 h; and then transferring the hollow fiber into a long-chain alkane solvent, treating the hollow fiber at the same temperature for 1-12 h, and after the completion of the treatment, immediately taking out the hollow fiber and drying the hollow fiber to obtain the hollow fiber membrane with a bicontinuous porous structure.

Abstract: A method of optimizing network processing in a system comprising a physical host and a set of physical network interface controllers (PNICs) is provided. The physical host includes a forwarding element. The method includes determining that a set of conditions is satisfied to bypass the forwarding element for exchanging packets between a particular data compute node (DCN) and a particular PNIC. The set of conditions includes the particular DCN being the only DCN connected to the forwarding element and the particular PNIC being the only PNIC connected to the forwarding element. The method exchanges packets between the particular DCN and the particular PNIC bypassing the forwarding element. The method determines that at least one condition in said set of conditions is not satisfied. The method utilizes the forwarding element to exchange packets between the particular DCN and the particular PNIC.

Abstract: Disclosed herein are compounds of Formula I?. Compounds of Formula I? inhibit, regulate and/or modulate kinase receptor, particularly Axl and Mer signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.

Abstract: Methods and systems for diagnosing a condition of a central nervous system are provided. A method includes providing a DBSI-MRI data set obtained from the central nervous system of the subject, and transforming the DBSI-MRI data set to obtain at least one DBSI biomarker value. The method further includes comparing each DBSI biomarker value to at least one corresponding threshold value from a diagnostic database to obtain a relation between each DBSI biomarker value and the at least one corresponding threshold value, and diagnosing the condition according to at least one diagnostic rule, wherein each diagnostic rule defines a candidate condition in terms of the relations between the at least one DBSI biomarker value and the at least one corresponding threshold value.

Abstract: Mechanisms are provided for generating an augmented reality representation of a real-world environment. An augmented reality (AR) system receives a captured digital image of the real-world environment and generates an initial estimate of a candidate point specifying an estimated location of an annotation point of a virtual object model within the captured digital image of the real-world environment. An accuracy of the initial estimate is calculated based on a function of characteristics of the annotation point and a function of characteristics of the candidate point and, in response to the evaluation of accuracy indicating that the initial estimate is not accurate, an annotation point location refinement operation is performed to generate a refined candidate point for aligning the annotation point with the captured digital image of the real-world environment. An AR representation of the real-world environment is generated based on the refined candidate point.

Abstract: The disclosure provides an approach for performance management. Embodiments include receiving, at a port of a router, a transport control protocol (TCP) or user datagram protocol (UDP) packet generated by a performance component of the router. Embodiments include identifying, by the router, a rule related to the TCP or UDP packet. Embodiments include forwarding, by the router, the packet to an interface of a kernel based on the rule. Embodiments include receiving, by the performance component, in response to the TCP or UDP packet, an additional packet from the interface of the kernel. Embodiments include determining, by the performance component, a performance metric based on the TCP or UDP packet and the additional packet.

Abstract: The disclosure provides an approach for routing traffic in a network. Embodiments include receiving, by a service router of an edge services gateway (ESG), a packet comprising a virtual network identifier (VNI) and a virtual local area network (VLAN) identifier. Embodiments include sending, by the service router, the packet to a virtual switch of the ESG based on the VNI of the packet. Embodiments include determining, by the virtual switch, a virtual routing and forwarding (VRF) router of the ESG for the packet based on the VLAN identifier. Embodiments include forwarding, by the virtual switch, the packet to the VRF router.

Abstract: The present disclosure provides compositions of anti-ceramide antibodies and antigen-binding fragments thereof. The disclosure further provides methods of preventing or inhibiting cell death in a subject in need thereof comprising administering the anti-ceramide antibodies or antigen-binding fragments to a subject. The subject in need thereof may suffer from an autoimmune disease, GI syndrome, or GvHD.

Abstract: This invention describes the preparation and its application of a cyanide bridged metal organic compound with intramolecular magnetic transition. The general structural formula of the compound is [(L2)(L1)M1(NC)M2(L3)m(CN)M1(L1)(L2)](PF6)6, n=2, 3, or 4. Damagnetic cyanidometal-bridge polynuclear compound [(L2)(L1)M1(NC)M(L)m(CN)M1(L1)(L2)](PF6)2 is synthesized by compound M(L1)(L2)X (X=Cl, Br or I) with redox activity is selected as the terminal group fragment, and M(L)2(CN)2 is selected as the central bridging ligand, using solution. Carry out electrochemical research on compound [(L2)(L1)M1(NC)M(L)m(CN)M1(L1)(L2)](PF6)2, select the appropriate oxidant, and obtain the one-electron oxidation product [(L2)(L1)M1(NC) M(L)m(CN)M1(L1)(L2)](PF6)3 and two-electron oxidation product [(L2)(L1)M1(NC)M(L)m(CN)M1(L1)(L2)](PF6)4. The cyanide-bridged metal organic compound is a cyanide bridged polynuclear compound that bridges by two diamagnetic metal fragments through a cyano group on a paramagnetic ion.

Abstract: Some embodiments provide a method for updating a core allocation among processes of a gateway datapath executing on a gateway computing device having multiple cores. The gateway datapath processes include a first set of data message processing processes to which a first set of the cores are allocated and a second set of processes to which a second set of the cores are allocated in a first core allocation. Based on data regarding usage of the cores, the method determines a second core allocation that allocates a third set of the cores to the first set of processes and a fourth set of the cores to the second set of processes. The method updates a load balancing operation to load balance received data messages over the third set of cores rather than the first set of cores. The method reallocates the cores from the first allocation to the second allocation.

Abstract: A communication method includes receiving an association request message, where the association request message includes information about a security algorithm supported by a second node, determining a target security algorithm of a signaling plane and a target MAC length of the signaling plane according to a first algorithm selection policy, where the target security algorithm of the signaling plane belongs to a set of security algorithms indicated by the information about the security algorithm supported by the second node, and generating a first MAC by using the target security algorithm of the signaling plane, where a length of the first MAC is the target MAC length of the signaling plane.

Abstract: A method, computer program product, and computer system for finding outliers in multidimensional time series samples. Each time series sample is divided into at least 2 sub samples having equal time duration. At least one prediction model is pre-trained using the sub samples and a prediction result for each sub sample for each prediction model is obtained by executing the pre-trained prediction models with the time series samples as input. A Shapely value corresponding to each prediction result is sub samples for each prediction model to generate multiple clusters of Shapely values for each prediction model. Highest ranking Shapely value outliers are determined from analysis of the multiple clusters. Highest ranking outlier sub samples corresponding to the highest ranking Shapely value outliers are identified.

Abstract: Disclosed is a benzopyrazole compound. Specifically disclosed are a compound as shown in formula (I) and a pharmaceutically acceptable salt thereof.

Abstract: The disclosure provides for a systems and methods for monitoring uterine contractions of a uterus of a mammal by reconstructing three-dimensional images of uterine surface electrical activity based on a noninvasively obtained body-uterus geometry and a plurality of body surface electrical potential maps.

Abstract: A nanobody and its application based on SARS-CoV-2 S protein S1 subunit are provided, and the present disclosure relates to biomedical technology. The present disclosure chooses the Spike RBD of SARS-CoV-2 as a target, and screens the nanobody targeting SARS-CoV-2 by using a nanobody library. After an ELISA test, the Spike RBD target of SARS-CoV-2 can be specifically identification while a SPIKE S1+S2 ECD target is identification, and a binding signal is relatively strong. The corresponding nanobody sequence is constructed into a prokaryotic expression vector for expression and purification to express the target nanobody successfully. After purification, the purity is greater than 90%. The ELISA test of VHH nanobody showed that the purified nanobody has higher affinity to the two targets.

Abstract: Gypsum panels and methods of making the same are provided. A method of making a gypsum panel includes forming a first gypsum slurry by combining stucco, water, a siliconate, and a phosphate salt or polymer, and setting the first gypsum slurry to form at least part of a core of the gypsum panel, wherein the gypsum panel displays a 2-hour water absorption test weight increase of at least 10 weight percent less than an otherwise identical comparative panel containing no phosphate salt or polymer in its core.

Abstract: The invention provides a process for preparing a cell-binding agent chemically coupled to a drug. The process comprises covalently attaching a linker to a cell-binding agent, a purification step, conjugating a drug to the cell-binding agent and a subsequent purification step.