Abstract: An open-ear Bluetooth® earphone includes an earphone body and a support frame. The support frame is configured to be plugged into a cavum concha of a wearer. The earphone body is provided with an audio source, and the support frame is installed on the earphone body and corresponds to the audio source. When in use, the support frame is configured to be firmly plugged into the cavum concha of the wearer to allow the earphone body to be worn on the ear of the wearer. The audio source corresponds to the ear canal of the wearer through the support frame, so that the sound emitted from the audio source is transmitted into the ear canal through the support frame. The audio source is directly opposite of the ear canal through the support frame to shorten the distance between the audio source and the ear canal.

Abstract: The present disclosure provides use of Clostridium ghonii combined with a tumor angiogenesis inhibitor in preparing a pharmaceutical product for treating a tumor. The present disclosure further provides a drug for treating a tumor, where the drug includes active ingredients of Clostridium ghonii and a tumor angiogenesis inhibitor.

Abstract: A media management system including an application layer, a system layer, and a solid state drive (SSD) storage layer. The application layer includes a media data analytics application configured to assign a classification code to a data file. The system layer is in communication with the application layer. The system layer includes a file system configured to issue a write command to a SSD controller. The write command includes the classification code of the data file. The SSD storage layer includes the SSD controller and erasable blocks. The SSD controller is configured to write the data file to one of the erasable blocks based on the classification code of the data file in the write command. In an embodiment, the SSD controller is configured to write the data file to one of the erasable blocks storing other data files also having the classification code.

Abstract: A slurrying device includes a slurrying tank and a rotor stirrer. The rotor stirrer includes a stirring drum, a transmission gear arranged at an end face of the stirring drum configured to face the slurrying tank, and a rotor stirring rod configured to extend from the stirring drum and into the slurrying tank to stir a slurrying liquid in the slurrying tank. The rotor stirring rod is meshed with the transmission gear and configured to revolve along a planar trajectory of the transmission gear while simultaneously rotating. The rotor stirrer further includes a driving device provided at the stirring drum and configured to drive the rotor stirring rod to rotate via the transmission gear.

Abstract: A continuously variable transmission with both equal-difference output and equal-ratio output includes an input mechanism, a hydraulic transmission mechanism, a planetary-gear-set convergence mechanism, an equal-difference output mechanism, an equal-ratio output mechanism, a clutch assembly, and a brake. The clutch assembly connects an output end of the input mechanism to an input end of the hydraulic transmission mechanism and the planetary-gear-set convergence mechanism and connects an output end of the hydraulic transmission mechanism to the planetary-gear-set convergence mechanism. The clutch assembly connects the planetary-gear-set convergence mechanism to the equal-difference output mechanism and the equal-ratio output mechanism. The clutch assembly connects the equal-ratio output mechanism to the equal-difference output mechanism.

Abstract: Some embodiments provide a method for forwarding data messages at multiple edge gateways of a logical network that process data messages between the logical network and an external network. At a first edge gateway, the method receives a data message, having an external address as a destination address, from the logical network. Based on the destination address, the method applies a default route to the data message that routes the data message to a second edge gateway and specifies a first output interface of the first edge gateway for the data message. After routing the data message, the method applies a stored NAT entry that (i) modifies a source address of the data message to be a public NAT address associated with the first edge gateway and (ii) redirects the modified data message to a second output interface of the first edge gateway instead of the first output interface.

Abstract: A system for proctoring online exams includes a client-side computing system and a visual analytics system. The client-side computing system includes a camera configured to obtain video data corresponding to a user while taking an exam and one or more input devices configured to obtain interaction data, wherein the interaction data includes mouse movements of the user while taking the exam. The visual analytics system is configured to obtain the video data and the interaction data from the client-side computing system, analyze the exam data to detect abnormal behavior by the user based at least in part on mouse movement data, and generate one or more visualizations of the analyzed exam data to be used in determining whether or not the user has cheated during the exam.

Abstract: Some embodiments provide a method for forwarding data messages at multiple edge nodes of a logical network that process data messages between a logical network and an external network. At a particular one of the edge nodes, the method receives a data message sent from a source machine in the logical network. The method performs network address translation to translate a source network address of the data message corresponding to the source machine into an anycast network address that is shared among the edge nodes. The method sends the data message with the anycast network address as a source network address to the external network. Each edge node receives data messages from source machines in the logical network and translates the source addresses of the data messages into the same anycast public network address prior to sending the data messages to the external network.

Abstract: A continuously variable transmission with both equal-difference output and equal-ratio output includes an input mechanism, a hydraulic transmission mechanism, a planetary-gear-set convergence mechanism, an equal-difference output mechanism, an equal-ratio output mechanism, a clutch assembly, and a brake. The clutch assembly connects an output end of the input mechanism to an input end of the hydraulic transmission mechanism and the planetary-gear-set convergence mechanism and connects an output end of the hydraulic transmission mechanism to the planetary-gear-set convergence mechanism. The clutch assembly connects the planetary-gear-set convergence mechanism to the equal-difference output mechanism and the equal-ratio output mechanism. The clutch assembly connects the equal-ratio output mechanism to the equal-difference output mechanism.

Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.

Abstract: Disclosed in the present disclosure is a method for extracting and separating various components from flaxseed meal based on a subcritical composite solvent, including the following steps: adding an extraction agent to flaxseed meal for subcritical extraction to obtain a crude flax lignan extract and crude flaxseed oil in one step, where the extraction agent includes n-butane and anhydrous ethanol at a volume ratio of 1:1; adding n-hexane to the crude flaxseed oil for fractional extraction, and conducting rotary evaporation to obtain flaxseed oil; and subjecting the flaxseed meal used to hot water extraction to obtain flaxseed gum. In the present disclosure, the subcritical composite solvent used in an extraction process can replace a large number of organic reagents used in a traditional extraction process, and has the characteristics of good solvent effect, environmental friendliness, recyclability, and low burden on the environment.

Abstract: The present invention belongs to the field of medicinal chemistry and relates to a class of substituted tricyclic compounds as PRMT5 inhibitors and the use thereof. Specifically, the present invention provides a compound represented by formula (A) or an isomer, pharmaceutically acceptable salt, solvate, crystal or prodrug thereof, a preparation method therefor, a pharmaceutical composition containing the compounds, and the use of the compounds or the composition for treating a disease mediated by PRMT5. The compounds of the present invention show significant inhibitory activity on PRMT5.

Abstract: Some embodiments of the invention provide a method for transmitting data messages via secure tunnels in a network. The method is performed at a gateway device. The method determines that a data message received at the gateway device should be sent via a secure interface of the gateway device. The method matches the data message to a firewall rule that maps to a particular secure tunnel used by the secure interface, with multiple different firewall rules mapping to multiple different secure tunnels used by the secure interface. The method encapsulates the data message with a header that comprises an indicator value specifying the particular secure tunnel and forwards the encapsulated data message to a destination interface.

Abstract: A method for recognizing an identity and a gesture based on radar signals includes: reading a radar echo signal reflected by various gestures of a tester and received by a radar sensor; frequency-mixing the radar echo signal with a radar transmission signal; after filtering and centralizing a frequency-mixed signal, training and obtaining a neural network capable of identity verification and a neural network capable of gesture recognition; in a real-time detection process, verifying an identity of a user; and if the identity is verified, determining that a gesture of the user is valid; verifying the gesture of the user and executing a corresponding operation according to correspondence between the gesture of the user and an operation. It can be determined by the method whether the gesture belongs to the corresponding user and whether the operation corresponding to the gesture is performed according to the determined result.

Abstract: A system and method deliver fluidized powder based on flue gas carrying waste slag and instant cooling steel slag. A first flue gas pipeline receives pressurized CO2-rich flue gas and in fluid communication with a fluidization air pipeline, a pressurization air pipeline and a supplementary air pipeline respectively and through them enters an upper discharge bin; a second flue gas pipeline receives the pressurized CO2-rich flue gas and in fluid communication with a gas-gas mixer, a dense phase discharge guide pipe first end extends into the upper discharge bin and receives high-pressure dense phase gas-powder flow of CO2-rich flue gas, and a dense phase discharge guide pipe second end is connected to the gas-gas mixer; a variable-pitch twin screw sealed conveyor discharge end extends into an upper discharge bin internal space, and is provided with an upwardly inclined gas-blocking segment.

Abstract: A pixel processing circuit, a reading method thereof and an image sensor are provided. The pixel processing circuit includes a pixel array comprising a plurality of pixel units arranged in a Bayer array, an Analog-to-Digital Converter (ADC) module comprising a plurality of analog-to-digital converters and a plurality of switch selection modules. The analog-to-digital converters are respectively located on the opposite first side and second side of the pixel array. The switch selection modules are set between the pixel array and the analog-to-digital converters to switch the connectivity between the pixel units and the analog-to-digital converters on the opposite sides of the pixel array so that signals of green pixel units are read by first analog-to-digital converters located at the first side of the pixel array, and signals of remaining color pixel units are read by second analog-to-digital converters that are located at the second side of the pixel array.

Abstract: Provided is a carbon dioxide fluidity control device comprising, a sample preparation tank, a high-pressure stirring unit, a reciprocating plunger pump and a booster pump, wherein the stirring unit comprises one or more high-pressure stirring tanks, each provided with an atomizing spray probe and a piston, wherein a discharge port of the sample preparation tank is connected to the atomizing spray probe via a plunger pump, which is connected to the piston to push the piston to reciprocate; the booster pump is connected to the high-pressure stirring tanks to provide supercritical carbon dioxide to the high-pressure stirring tank; and a discharge port of the high-pressure stirring tanks is connected to an oilfield well group. Provided is a carbon dioxide fluidity control method using the device, comprising mixing surfactants and nanoparticles with heated carbon dioxide, and injecting a microemulsion of supercritical carbon dioxide and nano-silicon dioxide into an oilfield well group.

Abstract: Example methods for a network device to perform address resolution handling. The method may comprise: in response to a first distributed router (DR) port of a first DR instance detecting an address resolution request from a second DR port of a second DR instance, generating a modified address resolution request that is addressed from a first address associated with the first DR port instead of a second address associated with the second DR port. The modified address resolution request may be broadcasted within a logical network that is connected to the first DR instance through network extension. The method may also comprise: in response to detecting an address resolution response that includes protocol-to-hardware address mapping information associated with an endpoint located on the logical network, generating and sending a modified address resolution response towards the second DR port of the second DR instance.