Abstract: A sweeping assembly for a cleaning device, includes: a brush holder defining an accommodating cavity therein; a main brushroll accommodated in the accommodating cavity of the brush holder, the main brushroll including a cleaning part located at a middle portion of the main brushroll and a connecting part located at an end of the main brushroll, the connecting part being connected to the brush holder or a driver of the cleaning device; and an anti-winding structure arranged at the brush holder, and including a first end connected to the brush holder, and a second end abutting against the brushroll.

Abstract: A preparation method for a decellularized matrix biomaterial, which combines specific pretreatment, degreasing, disinfection, decellularization, ?-Gal antigen removal and sterilization, and reserves the integrity of bioactive components and structures in a material to the maximum extent while effectively removing an antigenic substance of an animal tissue, so that a decellularized matrix biomaterial having low immunogenicity and high biological activity is obtained. In addition, the decellularized matrix biomaterial prepared by the method effectively reduces immunogen components, has good biocompatibility and biological safety, is beneficial to cell adhesion, aggregation and proliferation on the surface, and can be used as a high-activity biological matrix material to be applied to skin soft tissue defect, gingival recession and periodontal soft tissue repair.

Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.

Abstract: A method for enhancing compressive strength of a lead smelting water-quenched slag-based cementitious material by mechanical activation is provided, belonging to the technical field of solid waste resource treatment. The method includes following steps: grinding and activating water-quenched slag from lead smelting, then mixing with calcium-based solid waste, magnesium-based solid waste, magnesium oxide, portland cement and water, and performing a steam curing and a curing at normal temperature on cementitious material slurry obtained to obtain the lead smelting water-quenched slag-based cementitious material.

Abstract: An apriori guidance network for multitask medical image synthesis is provided. The apriori guidance network includes a generator and a discriminator, wherein the generator includes an apriori guidance module configured to convert an input feature map into a target modal image pointing to a target domain according to an apriori feature, and the apriori feature is a deep feature of the target modal image. The generator is configured to generate a corresponding target domain image by taking the apriori feature of the target modal image and source modal image data as an input. The discriminator is configured to discriminate an authenticity of the target domain image outputted by the generator.

Abstract: A protective dressing includes an outer dressing and an adhesive layer. The outer dressing includes an opening and a cavity sized to receive a phase-change material (PCM) insert inserted through the opening. The adhesive layer is configured to adhere to a patient's skin surrounding an anatomic site. When adhered to the patient's skin, the PCM insert modifies the patient's skin at the anatomic site. The PCM insert may be removed and replaced with another PCM insert. For example, a warm PCM insert may be replaced with a refrigerated PCM insert. The opening of the outer dressing may be self-sealing. The opening of the outer dressing may be sealed with an upper layer dressing coupled to the PCM cooling insert.

Abstract: The invention provides a nucleic acid testing cassette, including a substrate, a liquid storage component, a solid-reagent storage component, and an amplification reaction region, wherein the substrate is connected to the amplification reaction region; the liquid storage component and the solid-reagent storage component are disposed on the substrate, respectively; the liquid storage component is communicated with the solid-reagent storage component through a micro flow channel; and the solid-reagent storage component is communicated with the amplification reaction region through a micro flow channel.

Abstract: A liposome comprising bilayer and inner water phase is disclosed. Said inner water phase may contain sulfobutyl ether cyclodextrin and an active compound.

Abstract: The present invention relates to a method for preparing a wood modifier and a method for wood modification, and in particular, to a method for preparing a room temperature cured multifunctional wood modifier and a method for wood modification to solve the problems of high construction temperature, high toxicity, poor leaching-resistance and single function of existing wood modifiers. The method includes: step 1: weighing a hydrophobic polymer resin, an additive, a curing agent and a solvent, mixing and then stirring at room temperature to obtain a functional reagent A; step 2: weighing nanoparticles, a surface modifier and toluene, mixing and then stirring, cleaning with acetone, centrifuging, and drying to obtain a functional reagent B; step 3: adding a functional reagent C into the functional reagent A, evenly stirring, adding the functional reagent B, and performing ultrasonic processing to obtain the multifunctional wood modifier.

Abstract: The present invention discloses a steam disperser and a steamer having the same, comprising a steamer grid bottom plate and a steamer grid tube vertically connected with the steamer grid bottom plate. The steamer grid tube is positioned in the middle position of the steamer grid bottom plate; and a plurality of through vent holes are formed on the tube wall of the steamer grid tube and the steamer grid bottom plate. The present invention is provided with the steamer grid tube with a plurality of vent holes in the middle position of an original one-piece gas steamer grid. During use, steam and heat can be evenly distributed around food from bottom to top through the steamer grid tube to allow all the food on the steamer grid bottom plate to be evenly heated and cooked.

Abstract: The present invention relates to a method for preparing a wood modifier and a method for wood modification, and in particular, to a method for preparing a room temperature cured multifunctional wood modifier and a method for wood modification to solve the problems of high construction temperature, high toxicity, poor leaching-resistance and single function of existing wood modifiers. The method includes: step 1: weighing a hydrophobic polymer resin, an additive, a curing agent and a solvent, mixing and then stirring at room temperature to obtain a functional reagent A; step 2: weighing nanoparticles, a surface modifier and toluene, mixing and then stirring, cleaning with acetone, centrifuging, and drying to obtain a functional reagent B; step 3: adding a functional reagent C into the functional reagent A, evenly stirring, adding the functional reagent B, and performing ultrasonic processing to obtain the multifunctional wood modifier.

Abstract: Purified therapeutic nanoparticles are provided herein. Such nanoparticles comprise an active pharmaceutical ingredient and human serum albumin, wherein the weight ratio of human serum albumin to the active ingredient in the therapeutic nanoparticles is from 0.01:1 to 1:1, and wherein the nanoparticles are substantially free of free human serum albumin that is not incorporated in the nanoparticles. The present disclosure also provides pharmaceutical compositions that comprise the purified therapeutic nanoparticles and are also substantially free of free human serum albumin. Methods for preparing and using the purified therapeutic nanoparticles and compositions thereof are also provided.

Abstract: Purified therapeutic nanoparticles are provided herein. Such nanoparticles comprise an active pharmaceutical ingredient and human serum albumin, wherein the weight ratio of human serum albumin to the active ingredient in the therapeutic nanoparticles is from 0.01:1 to 1:1, and wherein the nanoparticles are substantially free of free human serum albumin that is not incorporated in the nanoparticles. The present disclosure also provides pharmaceutical compositions that comprise the purified therapeutic nanoparticles and are also substantially free of free human serum albumin. Methods for preparing and using the purified therapeutic nanoparticles and compositions thereof are also provided.

Abstract: A limiting plate control mechanism and a scooter luggage being capable to use this limiting device mechanism are provided. This limiting control device includes the first shell, second shell, sliding pressing block, first slider, second slider, first elastic element and the second elastic element. The first shell and second shell consists of the cavity shell. The sliding pressing block, first slider, second slider, first elastic element and second elastic element are all located in the cavity shell. This limiting plate control device has a simple structure and friendly operation, which brings convenience to the user. This scooter luggage has a simple structure, and is easy to operate and fold. A kind of button shell and a scooter luggage being capable to apply this button shell are provided. This button shell includes a spilt frame which is provided with the first baffle and second baffle. The first baffle is provided with a limiting bump, and the second baffle is provided with a limiting groove.

Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

Abstract: A protective dressing includes an outer dressing and an adhesive layer. The outer dressing includes an opening and a cavity sized to receive a phase-change material (PCM) insert inserted through the opening. The adhesive layer is configured to adhere to a patient's skin surrounding an anatomic site. When adhered to the patient's skin, the PCM insert modifies the patient's skin at the anatomic site. The PCM insert may be removed and replaced with another PCM insert. For example, a warm PCM insert may be replaced with a refrigerated PCM insert. The opening of the outer dressing may be self-sealing. The opening of the outer dressing may be sealed with an upper layer dressing coupled to the PCM cooling insert.

Abstract: A limiting plate control device is for a scooter luggage. The device includes first and second shells that form a cavity shell, and a sliding pressing block, first and second sliders, and first and second elastic elements that are all located within the cavity shell. The device comprises an extrusion mechanism configured to allow the first slider protrusion to retract into the cavity shell by pushing the pressing block and to allow the second slider protrusion to retract by further pushing the pressing block. The device has a simple structure and is easy to operate. Moreover, a button shell for a scooter luggage is provided. The button shell has a spilt frame which includes a first baffle with a limiting bump and a second baffle with a limiting groove. The button shell has a simple structure and is easy to assemble and operate.

Abstract: Purified therapeutic nanoparticles are provided herein. Such nanoparticles comprise an active pharmaceutical ingredient and human serum albumin, wherein the weight ratio of human serum albumin to the active ingredient in the therapeutic nanoparticles is from 0.01:1 to 1:1, and wherein the nanoparticles are substantially free of free human serum albumin that is not incorporated in the nanoparticles. The present disclosure also provides pharmaceutical compositions that comprise the purified therapeutic nanoparticles and are also substantially free of free human serum albumin. Methods for preparing and using the purified therapeutic nanoparticles and compositions thereof are also provided.

Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.