Patents by Inventor Yonghua Dong
Yonghua Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250058144Abstract: Disclosed are a negative-pressure drug loading apparatus and a negative-pressure drug loading method. When the apparatus is in use, drug particles to be loaded are placed into the particle storage tube, and a proper amount of drug solution is introduced. The particle storage tube is placed in the body, and the sealing space is sealed. A vacuum pump is used to execute a negative pressure operation in the body until the inside of the particle storage tube is pumped into a vacuum. An air valve of the vacuum pump is opened, such that the drug solution comes into the said particles under the action of pressure. After the pressure is stable, the particle storage tube is let stand for a period of time such that the drug solution stably stays in the said particles.Type: ApplicationFiled: September 2, 2024Publication date: February 20, 2025Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTDInventors: Guoxiang SUN, Yonghua DONG, Liangliang ZHAO, Lei JIN
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Publication number: 20240366300Abstract: The present invention provides a catheter apparatus with a carrier comprising right-handed wire helixes and left-handed wire helixes that are plainly or bi-axially woven into a tubular structure. A therapeutic assembly wraps around one of the wire helixes to stabilize an associated interstice of the tubular structure. The regular shape of the carrier may be quickly recovered after the carrier is seriously bent or distorted in an intravascular treatment.Type: ApplicationFiled: July 17, 2024Publication date: November 7, 2024Applicant: Shanghai Golden Leaf Medtech Co., Ltd.Inventors: Yonghua Dong, Meijun Shen, Liang Ji
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Patent number: 12064167Abstract: The present invention provides a method of treating or alleviating erectile dysfunction in a patient. Multiple electrodes are placed within a segment of the internal iliac artery of the patient and against blood vessel wall of the internal iliac artery. Radiofrequency energy is released through at least one of the multiple electrodes to nearby tissues, so as to increase the temperature of the nearby tissues and induce a thermal alteration of the nearby tissues.Type: GrantFiled: September 17, 2019Date of Patent: August 20, 2024Assignee: Shanghai Golden Leaf Medtech Co., Ltd.Inventors: Gaojun Teng, Yonghua Dong, Huaqing Yin, Qi Zhang, Meijun Shen, Jiulin Guo
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Publication number: 20240269381Abstract: Disclosed is a chain composition preparation apparatus, comprising a filling part, an injection part, a first connecting tube, a second connecting tube, a distribution valve and an outlet fluid tube. The filling part is in communication with the injection part via the first connecting tube, the distribution valve is in communication with the first connecting tube via the second connecting tube, and the outlet fluid tube is connected to the distribution valve; the distribution valve is also used to connect to an external gas supply part and a liquid supply part. The filling part is used to suck gas and liquid to sequentially enter the second connecting tube, to form a drug in an alternating gas-liquid dosage form. Thus, integration of drug configuration and drug injection can be achieved, so that convenience and efficiency of drug injection is improved.Type: ApplicationFiled: April 22, 2024Publication date: August 15, 2024Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTDInventors: Guoxiang SUN, Yonghua DONG
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Publication number: 20240246276Abstract: A sealing apparatus (10, 10?), comprising a sealing base plate (1, 1?), pressing parts (2, 2?), and a sealing turntable (3, 3?), wherein a plurality of pressing parts are enclosed at one end to form a shrink hole (101, 101?), and the sealing turntable drives the plurality of pressing parts to move synchronously so as to continuously shrink or expand the shrink hole. A sealing and cutting device, comprising the sealing apparatus (10, 10?), a cutting apparatus (20, 20?) and a conveying apparatus (70, 70?), wherein the conveying apparatus is arranged at a first end of the sealing apparatus so as to convey a material (60) along a set direction, and the cutting apparatus is arranged at a second end of the sealing apparatus for use in cutting the material.Type: ApplicationFiled: January 26, 2024Publication date: July 25, 2024Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTDInventors: Guoxiang SUN, Yonghua DONG
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Publication number: 20240173270Abstract: Disclosed are a pharmaceutical composition containing ethanol and a use thereof. The pharmaceutical composition can be used in vivo for animals, and is prepared from the following raw material: ethanol having a concentration no lower than 50% and a liquid ethanol thickener. The pharmaceutical composition containing ethanol provided in the present invention has high developability and sufficient fluidity without toxic side effect on normal tissues. The present invention does not solidify in blood and can break endothelial cells or mucous membrane superficial tissues so as to allow for permanent embolization.Type: ApplicationFiled: September 4, 2023Publication date: May 30, 2024Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTDInventors: Yonghua DONG, Yuan HE, Liangliang ZHAO, Miaoxia LI
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Publication number: 20240138791Abstract: The present invention provides a train-like pharmaceutical composition (configuration, or dosage form) comprising segments linearly arranged in series like cars of a train. When the pharmaceutical composition is administrated into a patient's body, some of the segments are “visible” to an instrument, but others are not. However, “invisible” segments can be estimated, deduced, calculated, or inferred from “visible” segments. The “invisible” segments can be used for neutralizing intratumoral lactic acidosis combined with glucose deprivation to control tumor, among other applications.Type: ApplicationFiled: December 15, 2023Publication date: May 2, 2024Applicant: Medessence Lifesciences (Suzhou), Inc.Inventors: Yonghua Dong, Rui Dong
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Publication number: 20240115134Abstract: The present invention provides medical imaging apparatus comprising a primary module for imaging a patient and a supplemental module. A controlling circuitry activates the supplemental module shortly before, during, or shortly after an imaging process using the primary module. Information, data or images of the patient acquired with the supplemental module is registered to the primary image. The invention can aid a radiologist to avoid confusion, mismatching, and other errors when he is reading the primary image; and can help a doctor to establish a correlation between conditions revealed by the primary image, and cutaneous conditions and anatomical change revealed by the supplemental module.Type: ApplicationFiled: December 17, 2023Publication date: April 11, 2024Inventor: Yonghua Dong
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Publication number: 20240115844Abstract: A particle storage tube (100) used for implanting microparticles into a body in cooperation with a puncture needle (500), and comprising an accommodation portion (1) and a drug delivery portion (2). The accommodation portion (1) is an elongated hollow tube having a channel (10) used to accommodate microparticles (4). One end of the accommodation portion (1) is connected to the drug delivery portion (2), and the other end of the accommodation portion (1) is an open part (11) used to discharge the microparticles out of the particle storage tube (100). The inner diameter of the channel (10) is 1.0-1.8 times the inner diameter of a lumen (502) of the puncture needle (500). An inner chamber (20) of the drug delivery portion (2) is in communication with the channel (10), and is used for delivering liquid medicine (200) to the channel (10).Type: ApplicationFiled: December 17, 2023Publication date: April 11, 2024Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTDInventors: Shaoge GU, Yonghua DONG, Lei JIN, Liangliang ZHAO, Guoxiang SUN
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Patent number: 11883092Abstract: The present invention provides a catheter apparatus with a carrier comprising right-handed wire helixes and left-handed wire helixes that are plainly or bi-axially woven into a tubular structure. A therapeutic assembly wraps around one of the wire helixes to stabilize an associated interstice of the tubular structure. The regular shape of the carrier may be quickly recovered after the carrier is seriously bent or distorted in an intravascular treatment.Type: GrantFiled: December 12, 2018Date of Patent: January 30, 2024Assignee: Shanghai Golden Leaf Medtech Co., Ltd.Inventors: Yonghua Dong, Meijun Shen, Liang Ji
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Publication number: 20230310827Abstract: A gas-liquid delivery connector, a gas-liquid delivery connector pair, and a gas-liquid delivery device. The gas-liquid delivery connector comprises: a male connector (1) for connecting a catheter, wherein the male connector (1) is provided with a first connecting channel (11) in the axial direction thereof; and a female connector (2) for connecting a microcatheter, wherein the female connector (2) is provided with a second connecting channel (21) in the axial direction thereof. The female connector (2) is connected to the male connector (1) such that the second connecting channel (21) is in butt joint with and in communication with the first connecting channel (11), and the inner diameter of the second connecting channel (21) is the same as the inner diameter of the first connecting channel (11).Type: ApplicationFiled: January 10, 2023Publication date: October 5, 2023Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTDInventor: Yonghua DONG
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Publication number: 20230277461Abstract: Disclosed are oxygen-containing particles, a manufacturing method therefor, and a use thereof. The oxygen-containing particles comprise a carrier that is safe for the human body and has a large number of micropores or pores distributed on the surface. The oxygen-containing particles further comprise a peroxide crystal attached to the surface of the micropores or pores of the carrier. The oxygen-containing particles in the present invention have the advantage of having microparticles in addition to a slow and controllable release of oxygen. The oxygen-containing particles can achieve local or systemic oxygen supply during embolization, implantation, perfusion and other operations. Furthermore, the oxygen-containing particles can also be used alone to supply oxygen for patients with pulmonary dysfunction.Type: ApplicationFiled: February 24, 2023Publication date: September 7, 2023Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTDInventors: Yonghua DONG, Yuan HE
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Publication number: 20230166124Abstract: The present invention discloses an intracavitary radiotherapy apparatus, which is used for carrying radioactive particles or particle strips, comprising: a body that is formed by winding metal wires, and is a wire mesh having a hollow cavity penetrating through same in the forward and backward directions; and a radioactive particle groove that is provided on the outer surface of the body, is a cylindrical wire mesh having a hollow cavity penetrating through same in the forward and backward directions, and is used for accommodating the radioactive particles or particle strips. The radioactive particle groove comprises a plurality of groove bodies arranged in parallel, and the spacing between two adjacent groove bodies is less than the length of the radioactive particles or particle strips.Type: ApplicationFiled: January 30, 2023Publication date: June 1, 2023Applicant: NANJING RONGSHENG MEDICAL TECHNOLOGY CO., LTD.Inventors: Yonghua DONG, Gaojun TENG, Jiansong JI, Huaqing YIN, Haidong ZHU, Jinhe GUO
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Publication number: 20230129393Abstract: A corrugated radiofrequency ablation catheter having wall-attaching adjustment wires (6, 6A, 6B, 6A?, and 6B?), provided with a strip-shaped connecting catheter, an electrode frame provided at the front end of the connecting catheter, and a control handle (20) provided at the rear end of the connecting catheter. The electrode frame is a corrugated electrode frame consisting of one or more corrugations, where one or more electrodes (2) respectively are distributed on the corrugations. The rear sections of the wall-attaching adjustment wires (6, 6A, 6B, 6A?, and 6B?) are slidably provided within one lumen of the connecting catheter and are connected at the rear extremities (60) onto a control element (22) provided on the control handle (20) or connected onto a control element (22) provided outside of the control handle (20).Type: ApplicationFiled: December 28, 2022Publication date: April 27, 2023Applicant: Shanghai Golden Leaf Med Tec Co., Ltd.Inventors: Yonghua DONG, Meijun SHEN
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Publication number: 20230089830Abstract: Disclosed are a pharmaceutical preparation with a tracing function, and a delivery system therefor. The pharmaceutical preparation comprises a first drug and a second drug in a liquid or gaseous state, wherein the first drug and the second drug are each divided into multiple sections, which are arranged in series at intervals in a conduit. One of the first drug and the second drug is a tracer drug that can be developed in a medical imaging device in the human body. The first drug and the second drug are immiscible and satisfy compatibility requirements. The pharmaceutical preparation can comprise an aerobic contrast agent, an aerobic embolic agent and an aerobic perfusion agent. Same can be applied to a variety of contrast techniques by means of a one-step simple operation, saving the dosage of a drug while maintaining a high concentration of the drug.Type: ApplicationFiled: October 24, 2022Publication date: March 23, 2023Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTDInventor: Yonghua DONG
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Publication number: 20230028772Abstract: A microparticle for drug loading, a drug loading microparticle, a particle containing tube, and an implantation system for the microparticle. The microparticle for drug loading includes a housing (31) and a drug loading part (34) located inside the housing and is used for being implanted into body tissues by means of a puncture needle (5); the housing (31) is provided with at least one micro-hole (33) running through the wall thickness of the housing (31); and the drug loading part (34) is located inside the housing (31) and is used for loading drugs. The microparticle for drug loading/drug loading microparticle can achieve different types of drug loading and different release speeds, can be directly implanted into tissues, and have the technical advantages of both microspheres and radioactive particles.Type: ApplicationFiled: September 20, 2022Publication date: January 26, 2023Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTDInventors: Yonghua DONG, Yuan HE
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Patent number: 11457977Abstract: The present invention provides a method for treating diabetes, a diabetes-associated condition or disorder, or symptoms thereof suffered by a subject such as a mammal (e.g. a human patient or a pet), comprising (1) placing multiple electrodes within at least one renal artery of the subject and against blood vessel wall of the at least one renal artery; (2) adhering a surface electrode on an external surface such as skin of the subject; and (3) releasing a therapeutically effective amount of radiofrequency energy through at least one of the multiple electrodes to nearby tissues, so as to increase the temperature of the nearby tissues and induce a thermal alteration of the nearby tissues.Type: GrantFiled: February 8, 2019Date of Patent: October 4, 2022Assignee: Shanghai Golden Leaf Medtech Co., Ltd.Inventors: Gaojun Teng, Yonghua Dong, Huaqing Yin
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Patent number: 11259868Abstract: A corrugated radiofrequency ablation catheter and an apparatus thereof. The radiofrequency ablation catheter is provided with a strip-shaped connecting catheter (10). An electrode frame is provided at the front extremity of the connecting catheter (10). A control handle (20) is provided at the rear extremity of the connecting catheter (10). The electrode frame is a corrugated electrode frame consisting of one or more corrugations. One or more electrodes (2) respectively are distributed on the corrugations. Slidable, supporting, wall-attaching adjustment wires (6) are provided within one lumen of the connecting catheter (10) and the electrode frame. The supporting, wall-attaching adjustment wires (6) are divided into a flexible segment (61) away from the control handle and a rigid segment (62) in proximity to the control handle.Type: GrantFiled: May 10, 2016Date of Patent: March 1, 2022Assignee: SHANGHAI GOLDEN LEAF MED TEC CO., LTD.Inventors: Yonghua Dong, Meijun Shen
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Patent number: 10850096Abstract: The present invention provides a method of relieving or alleviating abdominal cancer pain or improving pain VAS score in a cancer patient Multiple electrodes are placed within a segment of the abdominal aorta of the patient and against blood vessel wall of the abdominal aorta. Radiofrequency energy is released through at least one of the multiple electrodes to nearby tissues, so as to increase the temperature of the nearby tissues and induce a thermal alteration of the nearby tissues.Type: GrantFiled: December 31, 2018Date of Patent: December 1, 2020Assignee: Shanghai Golden Leaf Medtech Co., Ltd.Inventors: Gaojun Teng, Yonghua Dong, Huaqing Yin, Jiulin Guo
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Publication number: 20200281551Abstract: The present invention provides a train-like pharmaceutical composition (configuration, or dosage form) comprising segments linearly arranged in series like cars of a train. When the pharmaceutical composition is administrated into a patient's body, some of the segments are “visible” to an instrument, but others are not. However, “invisible” segments can be estimated, deduced, calculated, or inferred from “visible” segments. The “invisible” segments can be used for neutralizing intratumoral lactic acidosis combined with glucose deprivation to control tumor, among other applications.Type: ApplicationFiled: May 23, 2020Publication date: September 10, 2020Applicant: Medessence Lifesciences (Suzhou), Inc.Inventors: Yonghua Dong, Rui Dong