Abstract: The present application discloses variants of Pertuzumab. In particular, it discloses: an unpaired cysteine variant comprising Cys23/Cys88 unpaired cysteines in one or both variable light domains of Pertuzumab, an afucosylated variant of Pertuzumab, a low-molecular-weight-species (LMWS) of Pertuzumab, and a high-molecular-weight-species (HMWS) or Pertuzumab. The application further discloses the isolated variants, compositions, pharmaceutical compositions, and articles of manufacture comprising the variants, as well as methods of making and characterizing the variants and compositions thereof.

Abstract: The present application discloses variants of Pertuzumab. In particular, it discloses: an unpaired cysteine variant comprising Cys23/Cys88 unpaired cysteines in one or both variable light domains of Pertuzumab, an afucosylated variant of Pertuzumab, a low-molecular-weight-species (LMWS) of Pertuzumab, and a high-molecular-weight-species (HMWS) or Pertuzumab. The application further discloses the isolated variants, compositions, pharmaceutical compositions, and articles of manufacture comprising the variants, as well as methods of making and characterizing the variants and compositions thereof.

Abstract: The present application discloses variants of Pertuzumab. In particular, it discloses: an unpaired cysteine variant comprising Cys23/Cys88 unpaired cysteines in one or both variable light domains of Pertuzumab, an afucosylated variant of Pertuzumab, a low-molecular-weight-species (LMWS) of Pertuzumab, and a high-molecular-weight-species (HMWS) or Pertuzumab. The application further discloses the isolated variants, compositions, pharmaceutical compositions, and articles of manufacture comprising the variants, as well as methods of making and characterizing the variants and compositions thereof.

Abstract: A loudspeaker diaphragm, comprising a dome portion located at central position and a suspension ring portion located at edge position; the dome portion and/or the suspension ring portion comprise silk fabric and thermoplastic polyurethane combined with the silk fabric; and the silk fabric is coated with thermosetting adhesive. The method for manufacturing the loudspeaker diaphragm comprises following steps: a. coating the silk fabric with a thermosetting adhesive under a high temperature, and drying the silk fabric; b. hot pressing and combining the silk fabric and thermoplastic polyurethane to form a membrane; c. pressing the membrane to form the dome portion and/or the suspension ring portion. The dome portion, or both the dome portion and the suspension ring portion of the loudspeaker diaphragm comprise silk fabric coated with a thermosetting adhesive and thermoplastic polyurethane.

Abstract: The present application discloses variants of Pertuzumab. In particular, it discloses: an unpaired cysteine variant comprising Cys23/Cys88 unpaired cysteines in one or both variable light domains of Pertuzumab, an afucosylated variant of Pertuzumab, a low-molecular-weight-species (LMWS) of Pertuzumab, and a high-molecular-weight-species (HMWS) or Pertuzumab. The application further discloses the isolated variants, compositions, pharmaceutical compositions, and articles of manufacture comprising the variants, as well as methods of making and characterizing the variants and compositions thereof.

Abstract: A loudspeaker diaphragm, comprising a dome portion located at central position and a suspension ring portion located at edge position; the dome portion and/or the suspension ring portion comprise silk fabric and thermoplastic polyurethane combined with the silk fabric; and the silk fabric is coated with thermosetting adhesive. The method for manufacturing the loudspeaker diaphragm comprises following steps: a. coating the silk fabric with a thermosetting adhesive under a high temperature, and drying the silk fabric; b. hot pressing and combining the silk fabric and thermoplastic polyurethane to form a membrane; c. pressing the membrane to form the dome portion and/or the suspension ring portion. The dome portion, or both the dome portion and the suspension ring portion of the loudspeaker diaphragm comprise silk fabric coated with a thermosetting adhesive and thermoplastic polyurethane.

Abstract: Cylindrical screens and screen assemblies for use with perforated base pipe or casing for sand control in wellbores have generally longitudinally extending slots punched in the screen. The outer surface of the screen material is deformed below the inner surface causing apertures to form along the longitudinal edges of the slot. The slots are generally longitudinally aligned with the longitudinal axis of the cylindrical screens whether butt-welded or spiral-rolled and welded by determining the angle at which the slots need to be punched to result in such alignment. End caps which connect between the screen and the casing extend over the ends of the cylindrical screen and are welded thereto to minimize sand entry. At least one of the end caps may include an expansion joint to permit relative expansion and contraction between the screen and the casing particularly when used in thermal recovery operations.

Abstract: The present application discloses variants of Pertuzumab. In particular, it discloses: an unpaired cysteine variant comprising Cys23/Cys88 unpaired cysteines in one or both variable light domains of Pertuzumab, an afucosylated variant of Pertuzumab, a low-molecular-weight-species (LMWS) of Pertuzumab, and a high-molecular-weight-species (HMWS) or Pertuzumab. The application further discloses the isolated variants, compositions, pharmaceutical compositions, and articles of manufacture comprising the variants, as well as methods of making and characterizing the variants and compositions thereof.

Abstract: Described is a technology in which a low resolution image is processed into a high-resolution image, including by a two interpolation passes. In the first pass, missing in-block pixels, which are the pixels within a block formed by four neighboring original pixels, are given values by gradient diffusion based upon interpolation of the surrounding original pixels. In the second interpolation pass, missing on-block pixels, which are the pixels on a block edge formed by two adjacent original pixels, are given values by gradient diffusion based upon interpolation of the values of those adjacent original pixels and the previously interpolated values of their adjacent in-block pixels. Also described is a difference projection process that varies the values of the interpolated pixels according to a computed difference projection.

Abstract: Images are upsampled using a knowledge base derived from a plurality of high-quality training images. The knowledge base is used to refine a high-frequency component including high-frequency aspects of a high-resolution, low-frequency image, interpolated from a low-resolution full-frequency image, into a high-frequency component. An enhancement step is performed without using a knowledge base to construct a high-compatibility component from the low-resolution, full-frequency image. The low-resolution, full-frequency image is combined with the coarse high-frequency component to yield an enhanced high-frequency component. A second knowledge base step is performed to construct an improved high-frequency component from the enhanced high-frequency component. The improved high-frequency component is blended with a high-resolution, low-frequency image to yield a high-resolution image.

Abstract: This invention discloses the new uses of Lophatherum Total Flavones in medical, pharmaceutical, and healthcare fields. Lophatherum Total Flavones have effects of anti-bacteria, inhibiting bacteria, anti-inflammation, anti-prostatic hyperplasia, anti-platelet aggregation, anti-tumor, and promotion of immunity, etc., with safety and without toxicity, suitable for chronic oral administration, and especially suitable for prevention and treatment of senile chronic degenerative diseases; Lophatherum Total Flavones may be used in fields of pharmaceutical and foods, as a natural drug for prevention and treatment of prostatitis, prostatic hyperplasia, and prostate cancer, or as a dietary supplement.

Abstract: Described is a technology in which a low resolution image is processed into a high-resolution image, including by a two interpolation passes. In the first pass, missing in-block pixels, which are the pixels within a block formed by four neighboring original pixels, are given values by gradient diffusion based upon interpolation of the surrounding original pixels. In the second interpolation pass, missing on-block pixels, which are the pixels on a block edge formed by two adjacent original pixels, are given values by gradient diffusion based upon interpolation of the values of those adjacent original pixels and the previously interpolated values of their adjacent in-block pixels. Also described is a difference projection process that varies the values of the interpolated pixels according to a computed difference projection.

Abstract: Images are upsampled using a knowledge base derived from a plurality of high-quality training images. The knowledge base is used to refine a high-frequency component including high-frequency aspects of a high-resolution, low-frequency image, interpolated from a low-resolution full-frequency image, into a high-frequency component. An enhancement step is performed without using a knowledge base to construct a high-compatibility component from the low-resolution, full-frequency image. The low-resolution, full-frequency image is combined with the coarse high-frequency component to yield an enhanced high-frequency component. A second knowledge base step is performed to construct an improved high-frequency component from the enhanced high-frequency component. The improved high-frequency component is blended with a high-resolution, low-frequency image to yield a high-resolution image.