Abstract: A water outlet device includes a water outlet body and a movable shaft, the water outlet body is provided with a water inflow path, a water outflow path and a mounting channel; the mounting channel extends along a first direction with one end of the mounting channel communicating with the water inflow path, the other end of the mounting channel closed, and a side wall of the mounting channel provided with a first water passing hole communicated with the water outflow path; the movable shaft is slidably arranged in the mounting channel and is driven to slide relative to the water outlet body, and is provided with a water passing channel along the first direction; a side wall of the water passing channel is provided with a second water passing hole being opposite or staggered from the first water passing hole when the movable shaft slides.

Abstract: A peptide compound targeting a PD-1 receptor includes: a compound 1, a compound 2, a compound 3, a compound 4 and a compound 5; wherein the compounds 1-5 comprise amino acid sequences identical to SEQ ID NO: 1-5, respectively. A method for preparing the peptide compound targeting the PD-1 receptor includes steps of: using a solid-phase synthesis method for coupling amino acids of the compounds 1-5 to a solid-phase resin sequentially according to peptide sequences, and obtaining a target compound after cleavage by a cutting reagent, freeze-drying, and preparative purification. A method for preparing analgesic drugs includes using the peptide compound targeting the PD-1 receptor. The compounds 1-5 are capable of binding to PD-1, and have significant inhibitory effects on inflammatory pain and visceral pain under intrathecal administration; they are simple to synthesize, easy to be purified, and conducive to large-scale synthesis.

Abstract: Embodiments of the present disclosure are directed towards hybrid foam formulations that include: an isocyanate-reactive composition, and a high-functionality crosslinker; an azo type radical initiator; and an isocyanate.

Abstract: A rotary tillage, sowing, ditching and pressing compound operation machine includes a fertilization and sowing device, an intermediate rotary tillage and ditching device, a frame, a liftable ditcher, and a multi-stage press wheel device. The multi-stage press wheel device includes a front press wheel and a rear press wheel. The front press wheel includes a front press roller shaft, front press rollers, and connecting rods. The rear press wheel includes a connecting plate, a rear press roller shaft, and a rear press roller. A first end of the connecting plate is connected to the rear press roller shaft by a support, and the connecting plate is connected to the frame in a manner of a sliding pair. The rear press roller is mounted on the rear press roller shaft in a manner of a revolving pair, and the rear press roller is located behind the liftable ditcher.

Abstract: Provided is a rotary tillage, sowing, ditching and pressing compound operation machine, including a fertilization and sowing device (2), an intermediate rotary tillage and ditching device (4), a frame (1), a liftable ditcher (3), and a multi-stage press wheel device (5). The multi-stage press wheel device (5) includes a front press wheel (51) and a rear press wheel (52). The front press wheel (51) includes a front press roller shaft (511), front press rollers (512), and connecting rods (514). The rear press wheel (52) includes a connecting plate (521), a rear press roller shaft (523), and a rear press roller (524). A first end of the connecting plate (521) is connected to the rear press roller shaft (523) by a support, and the connecting plate (521) is connected to the frame (1) in a manner of a sliding pair. The rear press roller (524) is mounted on the rear press roller shaft (523) in a manner of a revolving pair, and the rear press roller (524) is located behind the liftable ditcher (3).

Abstract: The present invention relates to the field of nucleic acid sequencing. Specifically, provided in the present invention is a nucleotide analogue for sequencing. The nucleotide analogue carries a linker on the base or the ribose ring 3?-OH, and can be used for NGS sequencing. The present invention further relates to a kit containing the nucleotide analogue, and a sequencing method based on the nucleotide analogue.

Abstract: A modified nucleoside or nucleotide, the 3?-OH of the modified nucleoside or nucleotide being reversibly blocked; meanwhile, the present invention also relates to a kit comprising the nucleoside or nucleotide, and a sequencing method based on the nucleoside or nucleotide.

Abstract: The present invention relates to a composite film that is capable of converting mechanical energy to electrical energy. The film comprises a substrate and piezoelectric nanoparticles that are configured to form a plurality of pores. The present film is flexible and highly porous, providing high permittivity and beneficial porosity-mediated mechanical properties. When used in a piezoelectric nanogenerator (PNG), the film provides enlarged bulk film strain and reduced film impedance, resulting in a high efficiency PNG with increased output voltage and current as compared to known PNGs. A method of synthesizing the film is also described. The provided method is simple and cost-effective.

Abstract: The present disclosure provides a semiconductor structure and a forming method thereof. The semiconductor structure includes: a substrate, including a first side and a second side opposite to each other; a dielectric layer, provided at the first side of the substrate; a first through silicon via (TSV) structure, extending from a top surface of the dielectric layer to the first side of the substrate; and a second TSV structure, extending from the second side of the substrate to the first side of the substrate, coming into contact with the first TSV structure at the first side of the substrate, and having a preset opening width.

Abstract: Disclosed are inhibitors of mevalonate pathway as an efficient vaccine adjuvant and use thereof. In particular, the inhibitor is an acetoacetyl-CoA transferase inhibitor, a HMG-CoA synthase inhibitor, a HMG-CoA reductase inhibitor, a mevalonate kinase inhibitor, a phosphomevalonate kinase inhibitor, a mevalonate-5-pyrophosphate decarboxylase inhibitor, an isopentenyl pyrophosphate isomerase inhibitor, a farnesyl pyrophosphate synthase inhibitor, a geranylgeranyl pyrophosphate synthase inhibitor or a geranylgeranyl transferase (I, II) inhibitor. Also disclosed is an immunogenic composition comprising inhibitors of mevalonate pathway as an adjutant.

Abstract: A display device, including an irregularly-shaped display area disposed with a plurality of irregularly-shaped display pixels and at least one attachment device; and a pixel display area disposed adjacent to the irregularly-shaped display area; wherein each of the irregularly-shaped display pixels comprises an irregularly-shaped gate disposed below a driving thin-film transistor, and the irregularly-shaped gate changes a light-emitting brightness of the irregularly-shaped display pixel according to an adjustment voltage signal to balance light-emission uniformity of the irregularly-shaped display area and the pixel display area.

Abstract: A display panel and a method of manufacturing the same are disclosed. The display panel comprises a bending area for bending of the display panel, and the bending area includes a plurality of film layers which include a substrate, a first elastic layer disposed on the substrate, and a metal layer disposed on the first elastic layer. The metal layer includes a plurality of metal portions, and the metal portion includes at least one portion having an arch shape. A first elastic layer includes at least one curved surface on a side of the first elastic layer close to the metal layer, and each of the curved surfaces matches a shape of a side of the corresponding metal portion close to the first elastic layer.

Abstract: Disclosed are inhibitors of mevalonate pathway as an efficient vaccine adjuvant and use thereof. In particular, the inhibitor is an acetoacetyl-CoA transferase inhibitor, a HMG-CoA synthase inhibitor, a HMG-CoA reductase inhibitor, a mevalonate kinase inhibitor, a phosphomevalonate kinase inhibitor, a mevalonate-5-pyrophosphate decarboxylase inhibitor, an isopentenyl pyrophosphate isomerase inhibitor, a farnesyl pyrophosphate synthase inhibitor, a geranylgeranyl pyrophosphate synthase inhibitor or a geranylgeranyl transferase (I, II) inhibitor. Also disclosed is an immunogenic composition comprising inhibitors of mevalonate pathway as an adjuvant.

Abstract: An organic light-emitting diode (OLED) display panel and a mask are disclosed. The OLED display panel includes a first film layer, and a second film layer disposed on the first film layer and made of an organic material. The second film layer includes an edge slope corner formed at an acute angle less than a predetermined value. Since the edge slope corner of the second film layer is formed at the acute angle less than a predetermined value, a technical problem existing in conventional OLED display panels that edge slope corners of organic layers are formed at approximately a right angle can be mitigated.

Abstract: Embodiments are directed to a flexible high voltage thin film transistor (f-HVTFT) with a center-symmetric circular configuration. The f-HVTFT includes a ring-shaped oxide semiconductor channel, a ring-shaped gate, a ring-shaped source, and a circular drain. The source and gate each have multiple connections to respective electrode pads, enabling stable and identical electrical characteristics and blocking voltage while the f-HVTFT is subject to bending from random directions. The f-HVTFT enables a high blocking voltage over 100 V, on-current over 100 ?A, and low off-current of 0.1 pA, which makes it suitable for power management of self-powered wearable electronic systems.

Abstract: Embodiments of the present disclosure are directed towards hybrid foam formulations that include: an isocyanate-reactive composition, and a high-functionality crosslinker; an azo type radical initiator; and an isocyanate.

Abstract: A display device, including an irregularly-shaped display area disposed with a plurality of irregularly-shaped display pixels and at least one attachment device; and a pixel display area disposed adjacent to the irregularly-shaped display area; wherein each of the irregularly-shaped display pixels comprises an irregularly-shaped gate disposed below a driving thin-film transistor, and the irregularly-shaped gate changes a light-emitting brightness of the irregularly-shaped display pixel according to an adjustment voltage signal to balance light-emission uniformity of the irregularly-shaped display area and the pixel display area.

Abstract: An organic light-emitting diode (OLED) display panel and a mask are disclosed. The OLED display panel includes a first film layer, and a second film layer disposed on the first film layer and made of an organic material. The second film layer includes an edge slope corner formed at an acute angle less than a predetermined value. Since the edge slope corner of the second film layer is formed at the acute angle less than a predetermined value, a technical problem existing in conventional OLED display panels that edge slope corners of organic layers are formed at approximately a right angle can be mitigated.

Abstract: A method for treatment of a liver disease, the method including administering kinsenoside to a patient in need thereof.