Abstract: The present disclosure provides an earphone including a sound production component, an ear hook, and a microphone assembly. The microphone assembly includes a first microphone and a second microphone. The sound production component or ear hook includes a first sound hole and a second sound hole corresponding to the first microphone and second microphone, respectively. An extension line of a line connecting a projection of the first sound hole on a sagittal plane of the user and a projection of the second sound hole on the sagittal plane has an intersection point with a projection of an antihelix, a ratio of a first distance between the projection of the first sound hole on the sagittal plane and the projection of the second acoustic hole on the sagittal plane to a second distance between the projection of the second acoustic hole on the sagittal plane and the intersection point is 1.8-4.4.

Abstract: The present disclosure relates to a speaker device. The speaker device may include a speaker assembly and a supporting connector. The speaker assembly may include a speaker module and a button module. The supporting connector may be configured to contact with the human head and provide a vibration fulcrum for a vibration of the speaker assembly. A distance between a center of the button module and the vibration fulcrum may be not greater than a distance between a center of the speaker module and the vibration fulcrum.

Abstract: A speaker comprises a housing, a transducer residing inside the housing, and at least one sound guiding hole located on the housing. The transducer generates vibrations. The vibrations produce a sound wave inside the housing and cause a leaked sound wave spreading outside the housing from a portion of the housing. The at least one sound guiding hole guides the sound wave inside the housing through the at least one sound guiding hole to an outside of the housing. The guided sound wave interferes with the leaked sound wave in a target region. The interference at a specific frequency relates to a distance between the at least one sound guiding hole and the portion of the housing.

Abstract: A speaker comprises a housing, a transducer residing inside the housing, and at least one sound guiding hole located on the housing. The transducer generates vibrations. The vibrations produce a sound wave inside the housing and cause a leaked sound wave spreading outside the housing from a portion of the housing. The at least one sound guiding hole guides the sound wave inside the housing through the at least one sound guiding hole to an outside of the housing. The guided sound wave interferes with the leaked sound wave in a target region. The interference at a specific frequency relates to a distance between the at least one sound guiding hole and the portion of the housing.

Abstract: A speaker comprises a housing, a transducer residing inside the housing, and at least one sound guiding hole located on the housing. The transducer generates vibrations. The vibrations produce a sound wave inside the housing and cause a leaked sound wave spreading outside the housing from a portion of the housing. The at least one sound guiding hole guides the sound wave inside the housing through the at least one sound guiding hole to an outside of the housing. The guided sound wave interferes with the leaked sound wave in a target region. The interference at a specific frequency relates to a distance between the at least one sound guiding hole and the portion of the housing.

Abstract: A speaker comprises a housing, a transducer residing inside the housing, and at least one sound guiding hole located on the housing. The transducer generates vibrations. The vibrations produce a sound wave inside the housing and cause a leaked sound wave spreading outside the housing from a portion of the housing. The at least one sound guiding hole guides the sound wave inside the housing through the at least one sound guiding hole to an outside of the housing. The guided sound wave interferes with the leaked sound wave in a target region. The interference at a specific frequency relates to a distance between the at least one sound guiding hole and the portion of the housing.

Abstract: Provided herein are methods and cell-free systems for production of a recombinant antibody in which the antibody is directed against a target protein that is natively expressed as an intracellular protein. Also provided herein are modified cell-free systems for use in such methods in which the modified system is engineered to express a variant target protein that has a mutant epitope of the target epitope of an antibody.

Abstract: A method and device for managing establishment of a communications link between an external instrument (EI) and an implantable medical device (IMD) are provided. The method stores, in a memory in at least one of the IMD or the EI, a base scanning schedule that defines a pattern for scanning windows over a scanning state. The method enters the scanning state during which a receiver scans for advertisement notices during the scanning windows. At least a portion of the scanning windows are grouped in a first segment of the scanning state. The method stores, in the memory, a scan reset pattern for restarting the scanning state. Further, the method automatically restarts the scanning state based on the scan reset pattern to form a pseudo-scanning schedule that differs from the base scanning schedule and establishes a communication session between the IMD and the EI.

Abstract: The present disclosure relates to an open earphone. The open earphone may include a sound production device and an ear hook including a first part and a second part connected in sequence. The first part may be hooked and arranged between an auricle and a head of a user. The second part may extend to a front lateral surface of the auricle and may be connected to the sound production device. The sound production device may be worn at a position that is near an ear canal without blocking an earhole of the user. The sound production device may be at least partially inserted into an auricular concha cavity of the user. An overlap ratio of a projection area of the sound production device on a sagittal plane to a projection area of the auricular concha cavity on the sagittal plane may be not less than 44.01%.

Abstract: A speaker comprises a housing, a transducer residing inside the housing, and at least one sound guiding hole located on the housing. The transducer generates vibrations. The vibrations produce a sound wave inside the housing and cause a leaked sound wave spreading outside the housing from a portion of the housing. The at least one sound guiding hole guides the sound wave inside the housing through the at least one sound guiding hole to an outside of the housing. The guided sound wave interferes with the leaked sound wave in a target region. The interference at a specific frequency relates to a distance between the at least one sound guiding hole and the portion of the housing.

Abstract: The present disclosure relates to the technical field of a rehabilitation protective gear, in particular to a telescopic adjusting structure of a support arm and a knee brace. The telescopic adjusting structure of the support arm comprises an adjusting arm and a support arm guard movably connected along the length direction, and further comprises a telescopic adjusting mechanism. The telescopic adjusting mechanism comprises a pushing component, which is movably provided on the support arm guard; a locking component, one end of which is connected with the pushing component, and the other end of which is clamped with the adjusting arm, wherein when the pushing component moves, the locking component is disengaged from or locked with the adjusting arm. The telescopic adjusting mechanism is provided, so that the extension length matching between the adjusting arm and the support arm guard is adjusted.

Abstract: A port mode adaptation method includes a network device determining a status of a port on the network device. The method includes the network device setting a mode of the port to an Ethernet interface mode if the status of the port satisfies a first condition. In this way, when the network device identifies the mode of the port on the network device as the FlexE interface mode, and there is no link at the FlexE shim of the port, the network device may determine that a mode used by a port interconnected with the port is not a FlexE interface mode. In this case, the network device may adaptively set the mode of the port to the Ethernet interface mode, to ensure that the port on the network device can use a same mode as another port interconnected with the port.

Abstract: A cleaning device for a floor mopping machine comprises a bucket body for containing water, wherein a water removal member and a water feeding mechanism for conveying water from the bucket body to a wiping object of a floor mopping machine are arranged in the bucket body. During cleaning, the water feeding mechanism runs to convey water to the wiping object; and when water is removed, the water feeding mechanism stops running, and the wiping object of the floor mopping machine is wiped with the water removal member. Power of the water feeding mechanism is used for water feeding, and a wiping head is automatically cleaned, and can be wiped dry without any other operation after being cleaned; and the cleaning device is simple in structure, portable to use, less prone to damage and can be freely switched between a cleaning mode and a wipe-drying mode.

Abstract: The present disclosure provides eyeglasses including: an eyeglass rim; an eyeglass temple, the eyeglass temple comprising a control circuit or a battery; a rotating shaft, the rotating shaft being configured to connect the eyeglass rim and the eyeglass temple, so that the eyeglass rim and the eyeglass temple are relatively rotated around the rotating shaft, and the rotating shaft being disposed with a rotating shaft wiring channel along an axial direction; a connection wire, the connection wire passing through the rotating shaft wiring channel and extending to the eyeglass rim and the eyeglass temple, respectively; and a loud speaking component, the loud speaking component comprising an earphone core, the loud speaking component being connected to the eyeglass temple, the control circuit or battery in the eyeglass temple driving the earphone core to vibrate to generate a sound through the connection wire, and the sound comprising at least two formants.

Abstract: A video processing method includes: obtaining a first video frame and a second video frame in a target video, the first video frame being a previous frame of the second video frame; inputting the first video frame and the second video frame to a target neural network, and obtaining a target intermediate video frame output by the target neural network, the target neural network being trained based on an optical flow distillation constraint and a feature consistency constraint; and interpolating the target intermediate video frame between the first video frame and the second video frame.

Abstract: A method, system and external instrument are provided. The method initiates a communication link between an external instrument (EI) and an implantable medical device (IMD), established a first connection interval for conveying data packets between the EI and IMD and monitors a connection criteria that includes at least one of a data throughput requirement. A battery indicator or link condition of the communications link is between the IMD and EI. The method further changes from the first connection interval to a second connection interval based on the connection criteria.

Abstract: A loudspeaker device includes a speaker component, a first microphone element, and a second microphone element. The speaker component includes an earphone core and a core housing. The first microphone element is disposed on a first branch circuit board of a circuit board. The second microphone element is disposed on a second branch circuit board of the circuit board. The circuit board is configured to electrically connect to an audio signal wire, a first auxiliary signal wire, and a second auxiliary signal wire of an external control circuit. The audio signal wire, the first auxiliary signal wire, and the second auxiliary signal wire are electrically and respectively connected to the earphone core, the first microphone element, and the second microphone element through the circuit board. A board surface of the second branch circuit board is tilt with respect to a board surface of the first branch circuit board.

Abstract: The present disclosure reports a C-C chemokine type 2 receptor (CCR2) targeting mediated nanoimmunotherapy to treat cancer, such as pancreatic ductal adenocarcinoma (PDAC). Also disclosed herein is the use of a biodegradable copper nanocluster (CuNC) for enhanced loading of chemotherapeutic drug, such as Gemcitabine (Gem).

Abstract: The present disclosure relates to a speaker device including a circuit housing, an ear hook, a rear hook, and a speaker assembly. The speaker assembly may include a headphone core and a housing for accommodating the headphone core, the housing may include a housing panel facing a human body and a housing back opposite to the housing panel, and the headphone core may cause the housing panel and the housing back to vibrate. An absolute value of a difference between a first phase of a vibration of the housing panel and a second phase of a vibration of the housing back may be less than 60 degrees when a frequency of each of the vibration of the housing panel and the vibration of the housing back is between 2000 Hz and 3000 Hz.

Abstract: A material testing machine, including a machine body, a first fixing element, a second fixing element and a detection assembly; the first and the second fixing elements are mounted to the machine body, the first fixing element is configured to mount a first testing element, and the second fixing element is configured to mount a second testing element; in a first state, the first and the second testing elements are in sliding contact; in a second state, the first fixing element drives the first testing element to collide with the second testing element; the detection assembly is configured to detect a target parameter, and in the first state, the target parameter includes a friction force and/or, a friction sound between the first and the second testing elements; and in the second state, the target parameter includes a collision force received by the first or the second testing element.