Abstract: The present disclosure reports a C-C chemokine type 2 receptor (CCR2) targeting mediated nanoimmunotherapy to treat cancer, such as pancreatic ductal adenocarcinoma (PDAC). Also disclosed herein is the use of a biodegradable copper nanocluster (CuNC) for enhanced loading of chemotherapeutic drug, such as Gemcitabine (Gem).

Abstract: A loudspeaker device includes a speaker component, a first microphone element, and a second microphone element. The speaker component includes an earphone core and a core housing. The first microphone element is disposed on a first branch circuit board of a circuit board. The second microphone element is disposed on a second branch circuit board of the circuit board. The circuit board is configured to electrically connect to an audio signal wire, a first auxiliary signal wire, and a second auxiliary signal wire of an external control circuit. The audio signal wire, the first auxiliary signal wire, and the second auxiliary signal wire are electrically and respectively connected to the earphone core, the first microphone element, and the second microphone element through the circuit board. A board surface of the second branch circuit board is tilt with respect to a board surface of the first branch circuit board.

Abstract: The present disclosure relates to a speaker device including a circuit housing, an ear hook, a rear hook, and a speaker assembly. The speaker assembly may include a headphone core and a housing for accommodating the headphone core, the housing may include a housing panel facing a human body and a housing back opposite to the housing panel, and the headphone core may cause the housing panel and the housing back to vibrate. An absolute value of a difference between a first phase of a vibration of the housing panel and a second phase of a vibration of the housing back may be less than 60 degrees when a frequency of each of the vibration of the housing panel and the vibration of the housing back is between 2000 Hz and 3000 Hz.

Abstract: A material testing machine, including a machine body, a first fixing element, a second fixing element and a detection assembly; the first and the second fixing elements are mounted to the machine body, the first fixing element is configured to mount a first testing element, and the second fixing element is configured to mount a second testing element; in a first state, the first and the second testing elements are in sliding contact; in a second state, the first fixing element drives the first testing element to collide with the second testing element; the detection assembly is configured to detect a target parameter, and in the first state, the target parameter includes a friction force and/or, a friction sound between the first and the second testing elements; and in the second state, the target parameter includes a collision force received by the first or the second testing element.

Abstract: A method for managing power during communication with an implantable medical device, including establishing a communications link, utilizing a power corresponding to a session start power, to initiate a current session between an implantable medical device (IMD) and external device. A telemetry break condition of the communications link is monitored during the current session. The power utilized by the IMD is adjusted between low and high power levels, during the current session based on the telemetry break condition. The number of sessions is counted, including the current session and one or more prior sessions, in which the IMD utilized the higher power level, and a level for the session start power to be utilized to initiate a next session following the current session is adaptively learned based on the counting of the number of sessions.

Abstract: The embodiments of present disclosure disclose a loudspeaker. The loudspeaker may include an ear hook including a first plug end and a second plug end. The ear hook may be surrounded by a protection sleeve, and the protection sleeve may be made of an elastic waterproof material. The loudspeaker may include an earphone core housing configured to accommodate the earphone core, and the earphone core housing may be fixed to the first plug end through plugging, and may be elastically abutted against the protection sleeve elastically. The loudspeaker may include a circuit housing configured to accommodate a control circuit or a battery. The circuit housing may be fixed to the second plug end through plugging.

Abstract: This application provides techniques of generating non-fungible token props to be displayed in live rooms. The techniques comprise determining a virtual prop associated with one of a plurality of live rooms in which an online streamer performs livestreaming; determining a set of material components of the virtual prop; generating a set of visual materials based on configuring a plurality of visual materials for each of the set of material components; and generating a set of non-fungible token props corresponding to the virtual prop based on a plurality of sets of visual materials corresponding to the set of material components, wherein an identifier is assigned to each of the set of non-fungible token props for identification.

Abstract: A speaker device is provided. The speaker device may include a circuit housing, an ear hook, a rear hook, and a speaker assembly. The circuit housing may be configured to accommodate a control circuit or a battery. The ear hook may be connected to one end of the circuit housing and at least a part of the ear hook being covered by a first housing sheath. The rear hook may be connected to the other end of the circuit housing and at least a part of the rear hook being covered by a second housing sheath. The first housing sheath and the second housing sheath may cover at least a part of a periphery of the circuit housing from two ends of the circuit housing, respectively. The speaker assembly may include an earphone core and a core housing for accommodating the earphone core.

Abstract: The present disclosure relates to a speaker device. The speaker device may include a core housing, a circuit housing, an ear hook, and a housing sheath. The core housing may be configured to accommodate an earphone core. The circuit housing may be configured to accommodate a control circuit or a battery. The control circuit or the battery may be configured to drive the earphone core to vibrate to produce sound. The ear hook may be configured to connect the core housing and the circuit housing. The housing sheath may at least partially cover the circuit housing and the ear hook. The housing sheath may include waterproof material. The waterproof performance of the speaker device may be improved through sealed connections among various components of the speaker device in the present disclosure.

Abstract: The present disclosure discloses a loudspeaker apparatus. The loudspeaker apparatus may include a circuit housing accommodating a control circuit or a battery; an ear hook and a rear hook connected to both ends of the circuit housing, respectively. The ear hook may be at least partially covered by a first protective housing. The rear hook may be at least partially covered by a second protective housing. The first protective housing and the second protective housing at least partially cover a periphery of the circuit housing from both ends of the circuit housing in a sleeve manner, respectively. The loudspeaker apparatus may further include a speaker connected to one end of the ear hook, the speaker including an earphone core and an earphone core housing for accommodating the earphone core. The earphone core housing may include a housing panel facing the human body and a housing back opposite to the housing panel.

Abstract: A multi-directional radiation leaky coaxial cable is disclosed, including an inner conductor, an insulating layer, an outer conductor and a sheath which are sequentially and coaxially nested from inside to outside. The outer conductor is provided with at least two rows of slotted hole groups, the at least two rows of slotted hole groups are distributed at different angles in a circumferential direction of the outer conductor, each row of slotted hole group includes a plurality of slotted hole arrays which are periodically arranged along an axial direction of the outer conductor, each slotted hole array includes a plurality of slotted holes, pitches of the slotted hole groups are the same, and a periodic arrangement difference of two adjacent rows of slotted hole groups in the circumferential direction is half a pitch, so that a phase difference of respective excitation electric fields is 180°.

Abstract: An autonomous driving system includes a plurality of sensor combinations and a plurality of edge nodes, each of the plurality of sensor combinations includes at least one sensor; the plurality of edge nodes are in a one-to-one correspondence with the plurality of sensor combinations; and a first edge node in the plurality of edge nodes is configured to determine first perception information of a vehicle based on data collected by a first sensor combination corresponding to the first edge node. A central node is connected to the plurality of edge nodes. The central node is configured to delegate a first state decision function to the first edge node so that the first edge node determines that the vehicle enters a first state or determines a first driving policy of the vehicle in the first state by executing the first state decision function.

Abstract: The present disclosure discloses a loudspeaker apparatus. The loudspeaker apparatus may include a support connection member configured to contact with a user's head. The loudspeaker apparatus may include at least one loudspeaker assembly. The loudspeaker assembly may include an earphone core and a core housing configured to accommodate the earphone core. The core housing may be fixedly connected to the support connection member. At least one button module may be arranged on the core housing. The interior of the core housing may further include at least two microphones, and the at least two microphones may be arranged at a position different from a user's mouth. The loudspeaker apparatus may further include a control circuit or a battery accommodated in the support connection member. The control circuit or the battery may drive the earphone core to vibrate to generate sound.

Abstract: A recombinant antibacterial peptide TrSub, preparation method and application for the recombinant antibacterial peptide TrSub is disclosed, and belongs to the field of genetic engineering and biotechnology. The amino acid sequence of the recombinant antimicrobial peptide TrSub is shown in SEQ ID No. 1. The nucleotide sequence encoding the amino acid shown in SEQ ID NO.1 is shown in SEQ ID NO.2. The disclosure also provides a method for preparaing the recombinant antimicrobial peptide TrSub, wherein the recombinant antimicrobial peptide TrSub has an inhibitory effect on Escherichia coli, Salmonella, Staphylococcus aureus and Clostridium perfringens. The disclosure has good thermal stability, acid resistance, pepsin resistance and low hemolytic activity, and is beneficial to the application of the disclosure in the preparation of fee and feed additive.

Abstract: A prosthetic tissue valve and a method of treating the prosthetic tissue valve are provided. The method includes: decreasing a temperature of a chamber carrying the prosthetic tissue valve from a first preset temperature to a second preset temperature in a first cooling rate; decreasing the temperature of the chamber carrying the prosthetic tissue valve from the second preset temperature to a third preset temperature in a second cooling rate; and performing a drying process to the prosthetic tissue valve. The second preset temperature is a critical crystallization temperature and is greater than a crystallization temperature of the prosthetic tissue valve. The third preset temperature is lower than the crystallization temperature of the prosthetic tissue valve, and the second cooling rate is greater than the first cooling rate.

Abstract: A glove magnetic attraction kit device is provided and includes glove bodies, and magnetic attraction devices arranged on wrist parts of the glove bodies respectively. Each of the magnetic attraction devices includes a base, a blind hole is arranged in a middle of the base, and a hollow convex plate used to place a magnetic attraction body is arranged on the base. A side part of the convex plate is provided with an opening used for taking out the magnetic attraction body. The glove magnetic attraction kit device has advantages of strong practicability, reasonable structure, low cost, simple use, safety and reliability.

Abstract: A method, system and external instrument are provided. The method initiates a communication link between an external instrument (EI) and an implantable medical device (IMD), established a first connection interval for conveying data packets between the EI and IMD and monitors a connection criteria that includes at least one of a data throughput requirement. A battery indicator or link condition of the communications link is between the IMD and EI. The method further changes from the first connection interval to a second connection interval based on the connection criteria.

Abstract: The present disclosure relates to a speaker device. The speaker device may include a core housing, a circuit housing, an ear hook, and a housing sheath. The core housing may be configured to accommodate an earphone core. The circuit housing may be configured to accommodate a control circuit or a battery. The control circuit or the battery may be configured to drive the earphone core to vibrate to produce sound. The ear hook may be configured to connect the core housing with the circuit housing. The housing sheath may at least partially cover the circuit housing and the ear hook. The housing sheath may include waterproof material. The waterproof effect of a speaker device may be improved through sealed connections between various components of the speaker device in this the present disclosure.

Abstract: Embodiments of this application disclose a communication method and system applied to an MTN or an SPN. An MTN communication system includes a third communication apparatus connected to the first communication apparatus and the second communication apparatus by using a first MTN path and a second MTN path respectively. If the second MTN path is available, the third communication apparatus transmits data stream corresponding to a first client by using the second MTN path. If the second MTN path is unavailable, the third communication apparatus transmits the data stream corresponding to the first client by using the first MTN path, to ensure normal transmission of the data stream. In addition, the third communication apparatus may further implement load sharing.

Abstract: The present disclosure relates to a loudspeaker. The loudspeaker may include a loudspeaker mechanism, a fixing mechanism, and a connector. The loudspeaker mechanism may be configured to generate a vibration signal and transmit the vibration signal to the human body. The fixing mechanism may be configured to support and maintain the position of the loudspeaker mechanism. The connector may be configured to connect the loudspeaker mechanism with the fixing mechanism. The loudspeaker mechanism may at least include a first fixed position and a second fixed position. The first fixed position may be a fixed position of the loudspeaker when the loudspeaker is in a non-working state. The second fixed position may be a fixed position of the loudspeaker when the loudspeaker is in a working state. The connector may be configured to switch the loudspeaker mechanism between the first fixed position and the second fixed position.