Abstract: The present disclosure provides, for example, a compound represented by the general formula below or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of the compound or salt: wherein X1, X2, X3 and X4 are each independently —CR2? or N?, R2 is, for example, a halogen atom, R1 is, for example, —S(?O)2—NH—R8, R8 is, for example, a C1-6 alkyl group, R3 is, for example, a hydrogen atom, R5 is, for example, a halogen atom, R6 is, for example, a hydrogen atom, and R4 is, for example, a cyclopropyl group. The compounds, salts or solvates provided by the present disclosure exhibit high RAF/MEK complex-stabilizing activity and can be used for the treatment or prevention of cell proliferative disorders, particularly cancers.

Abstract: A wiper arm includes a spring for applying a biasing force to the rotation of an arm main body with respect to an arm head and enables the thickness of the wiper arm to be thinner while ensuring the suitable biasing force. The wiper arm also includes a coil spring and a spring plate. The arm main body includes a hinge block rotatably connected to the arm head through a hinge pin and a shaft section extending from the hinge block. The spring plate includes a front end wall including an insertion hole into which the shaft section is inserted and leg sections rotatably attached to the arm head through a roller pin. The coil spring is disposed to be coaxial with the shaft section and is held to be sandwiched between the front end surface of the hinge block and the front end wall of the spring plate.

Abstract: A method for disassembling a tower-type wind power generation facility eliminates scaffolding to be set up on the periphery of a tower body. An inner tower of a tower crane is built in an inner hollow of a tower body to install a crane apparatus at an upper end part, a nacelle and a wind power generator at an upper end part of the tower body are disassembled, the resulting disassembled objects are lowered through the outside of the tower body using the crane apparatus of the tower crane in the tower body, a working stage is provided on the inner tower after the wind power generator is disassembled, the tower body is disassembled via this stage provided on the inner tower, and the disassembled objects are lowered through the outside of the tower body using the crane apparatus of the tower crane.

Abstract: To provide a method of toppling a tower structure more safely, simply and quickly than in the conventional manner.

Abstract: There is provided a wiper arm which includes biasing means for applying a suitable biasing force to the rotation of an arm main body with respect to an arm head and enables the thickness of the wiper arm to be thinner while ensuring the suitable biasing force. A wiper arm 1 includes an arm head 2, an arm main body 3, a coil spring 4, and a spring plate 5. The arm main body 3 includes a hinge block 21 rotatably connected to the arm head 2 through a hinge pin 15 and a shaft section 22 extending from the hinge block 21. The spring plate 5 includes a front end wall 31 including an insertion hole 33 into which the shaft section 22 is inserted and leg sections 32A, 32B which are rotatably attached to the arm head 2 through a roller pin 18. The coil spring 4 is disposed to be coaxial with the shaft section 22 and is held to be sandwiched between the front end surface 21c of the hinge block 21 and the front end wall 31 of the spring plate 5.

Abstract: There is provided a wiper assembly that includes a wiper blade and a wiper arm, and a connecting member for a wiper assembly, the wiper assembly and the connecting member being configured so that the appearance of the wiper assembly can be improved, and the work of connecting the wiper blade and the wiper arm can be facilitated. In a wiper assembly 1, a clip housing 28 is included in a blade housing section 27 of a wiper arm 2, and a wiper blade 3 and the wiper arm 2 are joined in a state where a clip member 4 is housed within the clip housing 28. Retention sections 29 are provided at lower edges 26A of side walls 26 on both sides of the wiper arm 2, and the clip member 4 is retained by fitting the retention sections 29 into cutout parts 44 of the clip member 4.

Abstract: There is provided a wiper assembly that includes a wiper arm configured to retain a wiper blade in a state where at least a part of the wiper blade is housed within a blade housing section, the wiper assembly being configured so that a reduction in weight and a lowering of the manufacturing cost can be achieved. In a wiper assembly 1 configured to retain a wiper blade 3 by a wiper arm 2, by housing a support section 32 of the wiper blade 3 in a blade housing section 27 provided in an arm main body 23 of the wiper arm 2, the arm main body 23 is formed of metal, while the support section 32 is formed of resin. A plurality of projections 37 are provided on side surfaces 34 of the support section 32, and these projections 37 are made to come into contact with inward-facing surfaces 26B of side walls 26 of the arm main body 23.

Abstract: A demolishing method utilizes an aggregate stack demolishing scaffold apparatus mounted to an upper part of an aggregate stack including four smoke funnels arranged adjacent to each other. An uneven scaffold including one plate-shaped upper scaffold portion is placed on an upper end of each smoke funnel. A lower scaffold portion is coupled to the upper scaffold portion and located in lower positions in the smoke funnels with the upper scaffold portion being placed on the upper ends of the smoke funnels. A chain block suspends and supports the uneven scaffold from and on an inner wall of each smoke funnel, and adjusts a suspending height. With this configuration, the upper scaffold portion is located on the upper ends of the smoke funnels, and thus there is no possibility of contact between the scaffolds in the smoke funnels causing a worker to lose his balance, thereby improving safety.

Abstract: There is provided an aggregate stack demolishing scaffold apparatus capable of easily demolishing even an aggregate stack with safety at low cost, and a demolishing method using the apparatus. An aggregate stack demolishing scaffold apparatus 10 to be mounted to an upper part of an aggregate stack 130 including four smoke funnels 132 arranged adjacent to each other includes: an uneven scaffold including a one plate-shaped upper scaffold portion 14 that can be placed on an upper end of each smoke funnel 132, and lower scaffold portions 18 coupled to the upper scaffold portion 14 and located in lower positions in the smoke funnels 132 with the upper scaffold portion 14 being placed on the upper ends of the smoke funnels 132; and a chain block 28 capable of suspending and supporting the uneven scaffold from and on an inner wall of each smoke funnel 132, and adjusting a suspending height.

Abstract: A high-pressure washing liquid ejecting washing apparatus comprises a bar-shaped holder; and a plurality of high-pressure washing liquid ejecting nozzles arranged at constant intervals along a longitudinal direction of the bar-shaped holder, the holder being supported at both sides in a longitudinal direction thereof such that the holder is rotatable around its longitudinal axis, the holder being reciprocatingly rotated around the longitudinal axis within a predetermined rotational angle and the ejecting nozzles ejecting a high-pressure washing liquid to a washed surface of an object in a single straight-line shape to wash the object while the object is conveyed at a constant speed with respect to the holder, wherein the holder has a length which is not less than a length across the object and is disposed such that the holder is orthogonal to a direction in which the object is conveyed or is tilted with respect to the direction in which the object is conveyed, when viewed from a normal line direction of the w

Abstract: A high-pressure washing liquid ejecting washing apparatus comprises a bar-shaped holder; and a plurality of high-pressure washing liquid ejecting nozzles arranged at constant intervals along a longitudinal direction of the bar-shaped holder, the holder being supported at both sides in a longitudinal direction thereof such that the holder is rotatable around its longitudinal axis, the holder being reciprocatingly rotated around the longitudinal axis within a predetermined rotational angle and the ejecting nozzles ejecting a high-pressure washing liquid to a washed surface of an object in a single straight-line shape to wash the object while the object is conveyed at a constant speed with respect to the holder, wherein the holder has a length which is not less than a length across the object and is disposed such that the holder is orthogonal to a direction in which the object is conveyed or is tilted with respect to the direction in which the object is conveyed, when viewed from a normal line direction of the w

Abstract: A plate material vertical processing line that is capable of subjecting large-sized and thinned glass plates to scribing, venting, etc without degrading their quality, comprises a plurality of processing devices each having a modular structure; wherein each of the processing devices includes a platform; a belt conveyor that is mounted on the platform and is configured to convey a glass plate placed in a substantially upright position while supporting a lower end of the glass plate; and a fluid guide that is mounted on the platform and is configured to apply a fluid pressure to a surface of the glass plate to support the glass plate in the substantially upright position and in a non-contact state; and wherein the processing devices include a combination of at least two processing devices selected from a scribing device, a venting device, a chamfering device, a cleaning agent washing device, a water washing device, a high-pressure water spray device, and a glass plate turn device.

Abstract: A plate material vertical processing line that is capable of subjecting large-sized and thinned glass plates to scribing, venting, etc without degrading their quality, comprises a plurality of processing devices each having a modular structure; wherein each of the processing devices includes a platform; a belt conveyor that is mounted on the platform and is configured to convey a glass plate placed in a substantially upright position while supporting a lower end of the glass plate; and a fluid guide that is mounted on the platform and is configured to apply a fluid pressure to a surface of the glass plate to support the glass plate in the substantially upright position and in a non-contact state; and wherein the processing devices include a combination of at least two processing devices selected from a scribing device, a venting device, a chamfering device, a cleaning agent washing device, a water washing device, a high-pressure water spray device, and a glass plate turn device.

Abstract: A computer software program to design an optimum oligo-nucleic acid base sequence candidate from nucleic acid base sequences being analyzed using a computer, the program comprising: a first command to receive the specification of respective tolerated ranges of double-chain bond temperature, base sequence length and GC content, and to store the information on the priority order of respective items in the memory; a second command, while extending the partial sequence in the aforementioned nucleic acid base sequences being analyzed, to determine whether or not a sequence in each length falls within respective tolerated ranges based on the priority items received by the aforementioned first command, and if it does fall within the ranges, to output the partial sequence in the applicable length as an oligo-nucleic acid base sequence candidate; and a third command to display, based on the aforementioned priority order, the oligo-nucleic acid sequence candidate outputted by the aforementioned second command along wit

Abstract: There is provided a planetary reduction gear 10 between a gas turbine 1 and a generator 5. The planetary reduction gear includes elastic deformation unit 12 on an output side, and for the elastic deformation unit, a strain energy within an elastic limit is set to be larger than a fluctuation torque energy of the generator of a momentary voltage drop time. The elastic deformation unit 12 includes an elastic member which elastically connects an output shaft 10a of the planetary reduction gear to an outer ring 10b. Thereby, when an excessive torque is generated in the generator by a momentary voltage drop, service interruption, and the like for a short time, it is possible to maintain the operation of a power generation facility, and secure a power supply of an important load, and an installation length is shortened and the facility can be downsized.

Abstract: There is provided a planetary reduction gear 10 between a gas turbine 1 and a generator 5. The planetary reduction gear includes elastic deformation means 12 on an output side, and for the elastic deformation means, a strain energy within an elastic limit is set to be larger than a fluctuation torque energy of the generator of a momentary voltage drop time. The elastic deformation means 12 includes an elastic member which elastically connects an output shaft 10a of the planetary reduction gear to an outer ring 10b. Thereby, when an excessive torque is generated in the generator by a momentary voltage drop, service interruption, and the like for a short time, it is possible to maintain the operation of a power generation facility, and secure a power supply of an important load, and an installation length is shortened and the facility can be downsized.

Abstract: A computer software program to design an optimum oligo-nucleic acid base sequence candidate from nucleic acid base sequences being analyzed using a computer, the program comprising: a first command to receive the specification of respective tolerated ranges of double-chain bond temperature, base sequence length and GC content, and to store the information on the priority order of respective items in the memory; a second command, while extending the partial sequence in the aforementioned nucleic acid base sequences being analyzed, to determine whether or not a sequence in each length falls within respective tolerated ranges based on the priority items received by the aforementioned first command, and if it does fall within the ranges, to output the partial sequence in the applicable length as an oligo-nucleic acid base sequence candidate; and a third command to display, based on the aforementioned priority order, the oligo-nucleic acid sequence candidate outputted by the aforementioned second command along wit

Abstract: A computer software program and a method are provided to design an optimum oligo-nucleic acid sequence candidate from a nucleic acid base sequence. The program comprises a first command for receiving and storing a specified tolerance of double-chain bond temperature; a second command for computing the double-chain bond temperature of a partial sequence at each length, as extending the length; and a third command for determining whether or not the double-chain bond temperature computed by the second command falls within the tolerance specified by the first command, and in case it falls within the range, for outputting the partial sequence with the length as an oligo-nucleic acid sequence candidate. Based on the inputted tolerance of double-chain bond temperature, oligo-nucleic acid sequences with various lengths that meet the double-chain bond temperature condition can be obtained. An oligo-nucleic acid array mounted with the designed oligo-nucleic acid sequences is also provided.

Abstract: A clothes drier according to the present invention can minimize failures in a sensor and can satisfactorily detect drying processing irrespective of the environment. In the clothes drier, an atmospheric temperature sensor 44L for detecting the substrate temperature required to determine the termination of the drying processing is disposed outside a circulating duct 18 and is mounted on a control substrate 42 having a thermal capacity on which a microcomputer for controlling operations performed by the clothes drier is mounted. Since the sensor 44L is provided outside the circulating duct 18, the sensor 44L is less affected by dust and water, as compared with a case where it is provided inside the circulating duct 18.

Abstract: A zone-forming apparatus adapted to direct a jet-stream in a radial direction by a guide member, the jet-stream being emitted from jet-stream generator which is arranged above the apparatus, and an air curtain thus formed is utilized to define a working space.