Abstract: A microneedle including a projection having a through hole formed in the projection in a direction that the projection extends, and a tubular member having an end surface configured to support the projection when the end surface is pressed against a skin and a fluid is supplied through the through hole of the projection to the skin. The projection has a length H along the direction that the projection extends and the supporting surface has an area S such that a ratio of S/H is in a range of from 2.1 to 10.5.

Abstract: An injection device including a microneedle structure including a substrate having a first surface and a second surface opposite to the first surface, and a protrusion protruding from the first surface in a direction opposite to the second surface, the protrusion having a through hole which penetrates from a tip of the protrusion to the second surface in the direction of the protrusion such that a liquid flows through the through hole, and one or more check valves positioned to stop the liquid flowing from the second surface.

Abstract: A puncture injection instrument including a hollow needle body including a substrate having a first surface and a second surface opposite to the first surface, the hollow needle body having one or more projections which are formed on the first surface and each have a through hole penetrating from a distal end of the projection to the second surface of the substrate, and one or more probes positioned outside a region where the one or more projections are formed. The one or more probes include an ultrasound probe or an optical coherence tomography probe.

Abstract: An injection instrument including a hollow needle body including a substrate having a first surface and a second surface opposite to the first surface, the hollow needle body having at least one projection which is formed on the first surface and has a through hole penetrating from a distal end of the projection to the second surface of the substrate, a deforming member positioned outside a region where the at least one projection is formed, the deforming member being deformable to bulge in a bulging direction along a projecting direction of the projection beyond a plane flush with the first surface, and a pressure channel through which a fluid is supplied such that a fluid pressure is applied to the deforming member. The deforming member is deformable in the bulging direction in response to the fluid pressure.

Abstract: An operation tool for a fluid injector includes a selective movement mechanism which moves the fluid injector between a first protruding position and a second protruding position in a housing of an outer cylinder. When the fluid injector is at the first protruding position, microneedles of a multi-microneedle device are protruded out to a first distance from the first open end. When the fluid injector is at the second protruding position to discharge a fluid via the microneedles, the microneedles are protruded out to a second distance from the first open end, which is shorter than the first distance. The selective movement mechanism includes a rotational-linear movement conversion mechanism which moves the fluid injector between the first and second protruding positions along a longitudinal center line of the outer cylinder based on a direction and an amount of rotation of the outer cylinder relative to the fluid injector.

Abstract: A method of manufacturing a microneedle including forming a plurality of first linear grooves on a substrate in parallel to one another along a first direction using grinding and forming a plurality of second linear grooves on the substrate in parallel to one another in a second direction intersecting the first direction using grinding. At least one of the forming of a plurality of first linear grooves and the forming of a plurality of second linear grooves includes forming first stage grooves using a first dicing blade; and processing the first stage grooves by tracing the first stage grooves using a second dicing blade having a side surface different from that of the first dicing blade to thereby form second stage grooves.

Abstract: Disclosed is a nanocarbon material-composite substrate including a substrate, a three-dimensional structural pattern formed on the substrate, and a nanocarbon material formed on a surface of the substrate, wherein the nanocarbon material is disposed at least on side surfaces of the three-dimensional structural pattern.

Abstract: An array 1 with microprotrusions comprises a base 2 and tapered microprotrusions 3 each disposed on the base 2 and tapering down toward the tip from the bottom. Letting a distance from the tip to the bottom on an arbitrary side of each microprotrusion 3 as a and letting the length of a second line segment prepared by projecting a first line segment representing the distance a onto the base 2 as b, a relationship of 1.0<(a/b)?7.5 holds.

Abstract: A method of manufacturing a microneedle including the steps of forming a plurality of first linear grooves on a substrate in parallel to one another along a first direction using grinding, and forming a plurality of second linear grooves on the substrate in parallel to one another in a second direction intersecting the first direction using grinding.

Abstract: Disclosed is a nanocarbon material-composite substrate including a substrate, a three-dimensional structural pattern formed on the substrate, and a nanocarbon material formed on a surface of the substrate, wherein the nanocarbon material is disposed at least on side surfaces of the three-dimensional structural pattern.

Abstract: A method of manufacturing a microneedle including the steps of forming a plurality of first linear grooves on a substrate in parallel to one another along a first direction using grinding, and forming a plurality of second linear grooves on the substrate in parallel to one another in a second direction intersecting the first direction using grinding.

Abstract: A method of manufacturing a microneedle including the steps of forming a plurality of first linear grooves on a substrate in parallel to one another along a first direction using grinding, and forming a plurality of second linear grooves on the substrate in parallel to one another in a second direction intersecting the first direction using grinding.

Abstract: A method of manufacturing a microneedle including the steps of forming a plurality of first linear grooves on a substrate in parallel to one another along a first direction using grinding, and forming a plurality of second linear grooves on the substrate in parallel to one another in a second direction intersecting the first direction using grinding.

Abstract: A left-turn driving support system for supporting a driver of a vehicle waiting to make a left turn at an intersection where vehicles travel on the right side of a road. The system includes a light-reflecting material which reflects light from blinking signals of a turn signal of a second oncoming vehicle following a forefront oncoming vehicle, which are about to enter the intersection. The light-reflecting material is installed continuously along the centerline of the road and is sufficient long to detect a left-turn signal of the second oncoming vehicle.

Abstract: This invention relates to a removable grade hot melt pressure sensitive adhesive comprising from about 5% to about 30% by weight of the adhesive of a block copolymer having styrene endblocks and ethylene/butylene or ethylene/propylene midblocks and having a coupling efficiency of less than about 65% and a melt index of greater than about 20 grams/10 minutes; from about 10% to about 50% by weight of the adhesive of at least one block copolymer having styrene endblocks and a coupling efficiency from about 65% to about 100%; from about 20% to about 60% by weight of the adhesive of a tackifying resin and from about 10% to about 40% by weight of the adhesive of a liquid plasticizing oil.

Abstract: A left-turn driving support device at an intersection is characterized in that a luminescent material emitting light upon sensing blinking of the turn signal of a second oncoming vehicle following a forefront oncoming vehicle arriving at the intersection, is installed in a position from which the driver of a vehicle waiting to make a left turn is able to visually check the luminescent material.

Abstract: A device and method for producing single crystals by the Czohralski method can control the temperature distribution and thermal history of single crystals to improve the production efficiency and quality of single crystals. The device includes a cylinder coaxially surrounding a single crystal pulling rod, having an upper end airtightly connected to the ceiling of a pulling chamber and a lower end close to the surface of a melt in a crucible. A heat insulating element is attached to the lower end of the cylinder, and is surrounded by a surface of the crystal, the inside wall of the crucible and the surface of the melt. The heat insulating element is sized to occupy 30-95% by volume of the space above the melt, and the space has a height corresponding to the radius of the crystal.

Abstract: In a hydraulic brake for a transmission, an assist piston, a reaction piston and a main piston are accommodated on a cylinder. The assist piston has a first acting portion in abutment against the main piston, and the main piston has a second acting portion facing one end of stacked frictional engaging elements. The assist piston and the main piston are moved rightwardly by a hydraulic pressure supplied to a first oil chamber and a second oil chamber to bring the frictional engaging elements into engagement with one another. The first and second acting portions are superposed as viewed axially, thereby preventing a jarring of the assist piston and the main piston. In one embodiment, each of the pistons is formed from a pressed article, whereby the machining cost can be reduced and, moreover, oil passages connecting the first and second oil chambers can be provided in a simple manner.

Abstract: Frictional engagement elements of a first hydraulic clutch and frictional engagement elements of a second hydraulic clutch are supported on a common clutch drum on opposite sides of a snap ring. Openings are defined respectively in the clutch drum and an urging member which is formed integrally with a clutch piston of the second hydraulic clutch for urging the frictional engagement elements toward the snap ring. An urging member for urging the frictional engage elements toward the snap ring is connected to a clutch piston of the first hydraulic clutch and extends through the openings to the outside of the clutch drum. Thus, the pair of hydraulic clutches disposed in a tandem fashion can be operated stably without interference from each other.

Abstract: A support shaft is fixed to a casing of a transmission. A main shaft is relatively rotatably fitted to an inner periphery of the support shaft with a needle bearing interposed therebetween, and a clutch hub is relatively rotatably fitted to an outer periphery of the support shaft. An annular groove is defined around the outer periphery of the support shaft and divided into an oil discharge groove and an oil supply groove by a pair of weirs. An oil supplied from an oil passage is supplied to a canceller oil chamber through the oil supply groove and oil holes in the clutch hub. The oil in the canceller oil chamber is discharged through the oil holes, the oil discharge groove, oil passages in the support shaft, the needle bearing and oil passages in the main shaft.