Abstract: A sample processing device comprising a sample holding part, a reagent holding part, a reaction part, a flow path for connecting the sample holding part, reagent holding part, and reaction part, a plurality of cylinders, and a plurality of plungers respectively disposed in the plurality of cylinders so as to be capable of reciprocal motion, wherein fluid can circulate among the plurality of cylinders via the flow path and the cylinders are sealed by the plungers. This configuration makes it possible to maintain a sealed state such that an external substance does not enter into the sample processing device during sample processing and to easily carry out quantitative flow manipulation, and the like, of the sample.

Abstract: Provided are a bubble eliminating structure and a bubble eliminating method which eliminate bubbles in a liquid by agitating the liquid, and an agitating method using the same. A first groove 114, which is an upstream bubble eliminating groove, and a second groove 131, which is a downstream bubble eliminating groove, are branched from a mixing well 13. After starting suction of the liquid from mixing well 13 into the first groove 114, suction of the liquid from the mixing well 13 into the second groove 131 is started, and after completion of discharge of the liquid from the first groove 114 into the mixing well 13, discharge of the liquid from the second groove 131 into the mixing well 13 is completed. This operation is repeated to eliminate bubbles.

Abstract: A liquid chromatograph has a long-life flow passage switching valve with reduced abrasion caused by sliding of flow passage end portions of a stator and flow passage end portions of a rotor seal. The flow passage switching valve includes: a stator; and a rotor seal connected with a rotor configured to rotate and slide on a circumference with respect to the stator. The stator has stator flow passages that open to the rotor seal. The rotor seal has a rotor seal flow passage for coupling two or more of the stator flow passages. A flow passage end portion that is positioned at a tip end in a sliding direction of the rotor seal flow passage is positioned in a direction opposite to the sliding direction of the stator flow passage end portion to be connected to the rotor seal flow passage, at least at the start of sliding.

Abstract: To introduce a reagent with a small amount of residual liquid and enable a fluidic manipulation by deformation of an elastic film, a sealed type of sample processing device is configured with a reagent storage including a joint portion which joins an upper film and a lower film at a periphery of a storage space which stores a reagent between both films, an analysis chip including a lower surface fluid channel through which a liquid flows on a lower surface side and an upper surface fluid channel through which the liquid flows on an upper surface side, and an elastic film which seals the lower surface side of the analysis chip. A portion of the lower film is joined to the upper surface side of the analysis chip, a removed portion, in which the lower film is partially removed, is in an upper part of the upper surface fluid channel.

Abstract: Provided is a specimen-processing device configured so that a flow operation can be performed by deforming an elastic membrane. The present invention has an analysis chip that is a processing unit having a first flow path through which a liquid flows on a lower-surface side, a drive unit that controls air, a membrane that is an elastic membrane disposed between the processing unit and the drive unit, and an air pressure control unit that switches the elastic membrane between adhering to the processing-unit side and adhering to the drive-unit side. The processing unit has formed therein a circulation groove that is a second flow path through which air flows, the circulation groove being formed on the opposite side from the side where the drive unit is disposed, and an adhesion film that is a hermetic sealing film, the adhesion film being provided above the second flow path of the processing unit.

Abstract: A temperature control device has a temperature control target for holding, in the inside thereof, a DNA-containing solution, the temperature of which is to be adjusted with a single temperature control unit, a first heat transfer unit which is in contact with the temperature control unit and transfers heat between the temperature control unit and a temperature control target. A second heat transfer unit is in contact with the first heat transfer unit and the temperature control target and transfers heat between the first heat transfer unit and the temperature control target or is in contact with the temperature control unit and the temperature control target and transfers heat between the temperature control unit and the temperature control target, and in that the temperature control target is sandwiched by the first heat transfer unit and the second heat transfer unit, and the second heat transfer unit is pressed.

Abstract: A blood collecting device collects blood in a short time after puncture without scattering the blood into the open air other than a container for collecting the blood. One of representative blood collecting devices has a container unit that includes a screw portion, a holder that holds the container unit serving as a system whose one end is closed, a puncture unit that can be attached to the container or the holder, a through-hole of the puncture unit, and a puncture unit protection member that protects the puncture unit and the container unit.

Abstract: This sample processing device comprises: an analysis chip having a flow path on a lower surface side; a drive unit having a plurality of recesses on an upper surface side; an elastic film positioned between the analysis chip and the drive unit; and an air pressure control unit that switches whether the elastic film is adhered to the analysis chip side or adhered to the drive unit side. The analysis chip includes a quantitative flow path for quantifying liquid, and at least four branch flow paths branched from the quantitative flow path. The drive unit includes recesses below each of the ends of the four branch flow paths not on the quantitative flow path side, and each of the recesses communicates with the air pressure control unit.

Abstract: Provided are a bubble eliminating structure and a bubble eliminating method which eliminate bubbles in a liquid by agitating the liquid, and an agitating method using the same. A first groove 114, which is an upstream bubble eliminating groove, and a second groove 131, which is a downstream bubble eliminating groove, are branched from a mixing well 13. After starting suction of the liquid from mixing well 13 into the first groove 114, suction of the liquid from the mixing well 13 into the second groove 131 is started, and after completion of discharge of the liquid from the first groove 114 into the mixing well 13, discharge of the liquid from the second groove 131 into the mixing well 13 is completed. This operation is repeated to eliminate bubbles.

Abstract: The present invention provides a pretreatment device for a sample for analysis that makes it possible to send a sample liquid to an arbitrary treatment module connected to a sample liquid conveyance flow route, and an analysis system using the same. A pretreatment device for a sample for analysis according to the present invention is at least provided with a plurality of sample liquid treatment modules for introducing a sample liquid or carrying out prescribed pretreatment on the sample liquid, a first flow path for conveying the sample liquid or the pretreated sample liquid between the plurality of sample liquid treatment modules, and a conveyance direction switching part for switching the conveyance direction of the sample liquid or the pretreated sample liquid in the first flow path.

Abstract: Provided are: a flow path switching valve that reduces the pressure load in a contact surface outer peripheral section of the flow path switching valve and inhibits friction between constituent components; and a liquid chromatographic device using the flow path switching valve. The flow path switching valve is provided with a stator having a plurality of through holes and a seal having conduction grooves for causing the through holes to conduct. The seal has a first portion present vertically beneath a region comprising at least a surface of contact with the stator, and a second portion having lower rigidity than the first portion, on the outside of the first portion. Due to this configuration, it is possible to reduce the pressure load when a flow path of a liquid is switched under high-pressure conditions, and inhibit the phenomenon of friction itself.

Abstract: A blood collecting device collects blood in a short time after puncture without scattering the blood into the open air other than a container for collecting the blood. One of representative blood collecting devices has a container unit that includes a screw portion, a holder that holds the container unit serving as a system whose one end is closed, a puncture unit that can be attached to the container or the holder, a through-hole of the puncture unit, and a puncture unit protection member that protects the puncture unit and the container unit.

Abstract: A chemical analysis apparatus includes a liquid delivery device and a liquid discharge unit discharging delivered liquids, the liquid delivery device including: a first liquid delivery unit delivering a first liquid containing an analysis object; a second liquid delivery unit delivering a second liquid not containing an analysis object; a measurement unit measuring physical properties of the delivered first liquid; first and second liquid pools containing the delivered first liquid and second liquid; and a plurality of passive valves. The apparatus further includes: a first flow passage connecting the first liquid delivery unit and the liquid delivery device; a second flow passage connecting the measurement unit and the second liquid pool; a third flow passage connecting the second liquid delivery unit and the liquid discharge unit; a first air hole provided in the first liquid pool; and a second air hole provided in the second liquid pool.

Abstract: The present invention is such a plug application and removal device that mist which is generated upon plug removal of a sample container or a reagent container is not peripherally scattered, or is such a sample processing device that mist which is generated upon dispensing of a sample or a reagent into a container is not mixed to another container. A plug application and removal device has a container holding mechanism that holds a container housing liquid inside and applied with a plug, and has a plug application and removal mechanism that removes or applies the plug from/to the container. The plug application and removal device has: a control mechanism for controlling movement of liquid or mist spilled out of the container upon a process of removal or application of the plug by the plug application and removal mechanism.

Abstract: Provided are: a flow path switching valve that reduces the pressure load in a contact surface outer peripheral section of the flow path switching valve and inhibits friction between constituent components; and a liquid chromatographic device using the flow path switching valve. The flow path switching valve is provided with a stator having a plurality of through holes and a seal having conduction grooves for causing the through holes to conduct. The seal has a first portion present vertically beneath a region comprising at least a surface of contact with the stator, and a second portion having lower rigidity than the first portion, on the outside of the first portion. Due to this configuration, it is possible to reduce the pressure load when a flow path of a liquid is switched under high-pressure conditions, and inhibit the phenomenon of friction itself.

Abstract: In some examples, a liquid feeding device includes a main flow passage in which a fluid may be fed between an upstream side and a downstream side. A first flow passage may branch from the main flow passage, and may include a narrow flow passage at a terminal end portion, having a smaller cross-sectional area than the first flow passage. A liquid feeding mechanism may feed the fluid to the main flow passage and the first flow passage. The narrow flow passage may suppress the fluid from leaking from first flow passage. Thus, the liquid feeding device may quantitatively determine a first volume of the fluid by filling the first flow passage with the fluid, and subsequently feeding the quantitatively determined fluid back to the main flow passage.

Abstract: The present invention provides a pretreatment device for a sample for analysis that makes it possible to send a sample liquid to an arbitrary treatment module connected to a sample liquid conveyance flow route, and an analysis system using the same. A pretreatment device for a sample for analysis according to the present invention is at least provided with a plurality of sample liquid treatment modules for introducing a sample liquid or carrying out prescribed pretreatment on the sample liquid, a first flow path for conveying the sample liquid or the pretreated sample liquid between the plurality of sample liquid treatment modules, and a conveyance direction switching part for switching the conveyance direction of the sample liquid or the pretreated sample liquid in the first flow path.

Abstract: A reagent holding container is provided that is capable of storing a reagent in a stable state over a long period of time and simply delivering a held reagent. A reagent holding container having a flexible material and a perforable material, wherein a plunger functions both to deform the flexible material of the reagent holding container and perforate the perforable material of the reagent holding container.

Abstract: A chemical analysis apparatus includes a liquid delivery device and a liquid discharge unit discharging the delivered first liquid and second liquid, the liquid delivery device including: a first liquid delivery unit delivering a first liquid containing an analysis object; a second liquid delivery unit delivering a second liquid not containing an analysis object; a measurement unit measuring physical properties of the delivered first liquid; a liquid pool containing the delivered first and second liquid; and a plurality of passive valves. The liquid pool includes first and second liquid pools. The apparatus further includes: a first flow passage connecting the first liquid delivery unit and the liquid delivery device; a second flow passage connecting the measurement unit and the second liquid pool; a third flow passage connecting the second liquid, delivery unit and the liquid discharge unit; a first air hole provided in the first liquid pool; and a second air hole provided in the second liquid pool.

Abstract: The liquid feeding device includes a branched portion at which a fluid is branched into a main flow passage that feeds the fluid from an upstream side to a downstream side and a first flow passage being branched from the main flow passage; a narrow flow passage being provided at a terminal end portion, and has a smaller cross-sectional area than the first flow passage; and a liquid feeding mechanism which feeds the fluid to the main flow passage and the first flow passage, wherein the narrow flow passage suppresses the fluid, being fed from the main flow passage side to the first flow passage using the mechanism in the branched portion, from leaking from first flow passage, quantitatively determines fluid as a first volume by filling the first flow passage, which has the first volume, with the fluid, and feeds the quantitatively determined fluid to the main flow passage.