Abstract: A corona discharge device including a corona electrode provided with multiple sharpened tip portions in a row includes a cleaning member which cleans the tip portions of the corona electrode while reciprocating along a predetermined movement direction set in advance with the tip portions biting into the cleaning member. A cleaning position at a surface of the cleaning member is different in a direction intersecting a longitudinal direction of the corona electrode between when the cleaning member moves toward one side in the movement direction and when the cleaning member moves toward another side in the movement direction.

Abstract: To provide an autoserum-containing bone marrow cell culture system, whereby bone marrow cells, which are collected from a subject without using an anticoagulant, are subjected to an anticoagulation treatment using a medium in a liquid-tight state, cultured and then further cultured using the serum of said subject which is prepared in a liquid-tight state; an autoserum-containing bone marrow cell culture method; and a method for producing a medicinal composition which comprises, as the active ingredient, autoserum-containing cultured bone marrow cells. [Solution] An autoserum-containing bone marrow cell culture system for culturing bone marrow cells, which are collected from a subject without using an anticoagulant, using the serum of said subject, said system comprising a bone marrow cell suspension-storing device, a collected blood-storing device, an autoserum-acquiring device, and a bone marrow cell-culturing device.

Abstract: A culture system has a culture bag for suspending and culturing pluripotent stem cells in a culture medium; a waste liquid container for storing used culture medium that is connected to the culture bag; a fresh medium container for storing a fresh culture medium that is connected to the culture bag; three-way stopcocks for switching flow channels from the culture bag to the waste liquid container or the fresh culture medium container, etc.; a trap portion for trapping the pluripotent stem cells in the culture medium in the flow toward the waste liquid container side; and a filter portion for subculturing that is formed in fourth and fifth flow channels in parallel to a first flow channel. The first flow channel connects the trap part to the culture bag, and has a mesh by which a cell mass of the pluripotent stem cells can be divided. A pump is used to pump the liquid in the individual flow channels.

Abstract: To provide an autoserum-containing bone marrow cell culture system, whereby bone marrow cells, which are collected from a subject without using an anticoagulant, are subjected to an anticoagulation treatment using a medium in a liquid-tight state, cultured and then further cultured using the serum of said subject which is prepared in a liquid-tight state; an autoserum-containing bone marrow cell culture method; and a method for producing a medicinal composition which comprises, as the active ingredient, autoserum-containing cultured bone marrow cells. [Solution] An autoserum-containing bone marrow cell culture system for culturing bone marrow cells, which are collected from a subject without using an anticoagulant, using the serum of said subject, said system comprising a bone marrow cell suspension-storing device, a collected blood-storing device, an autoserum-acquiring device, and a bone marrow cell-culturing device.

Abstract: A process unit includes a photoreceptor drum, a frame and seal members. The photoreceptor drum has drum flanges protruded outwardly from both end surfaces of a substrate. The frame supports the photoreceptor drum rotatably. The seal members are provided between both end surfaces of the photoreceptor drum and the frame, and support the drum flanges. Each of the seal members includes an elastic member and a hard member. The elastic member and the hard member are adhered and laminated with each other in an axial direction of the photoreceptor drum. Furthermore, the hard member is arranged so as to be brought into contact with the photoreceptor drum.

Abstract: An object of the present invention is to provide a method for preserving pancreatic islet, a container for preserving pancreatic islet and a kit for transplanting pancreatic islet in order to effectively preserve the pancreatic islet. The present invention presents; a method for preserving a liquid including pancreatic islet in a container for preserving pancreatic islet, wherein at least a part of the container wall face consists of a film having an oxygen permeation coefficient of 2500 cm3/m2·day·atm or greater; a method for preserving a liquid including pancreatic islet in a container for preserving pancreatic islet, wherein at least a part of the container wall face consists of a film having a carbon dioxide permeation coefficient of 1000 to 20000 cm3/m2·day·atm; and a container for preserving pancreatic islet for use in the above-described method, and a kit for transplanting pancreatic islet comprising the container for preserving pancreatic islet.

Abstract: Provided is a means suitable for mass culture of adherent cells and which allows easy and safe collection of the cultured adherent cells. A cell culture kit has a culture bag having flexibility, such a level of hydrophilicity that the culture of adherent cells can be achieved, and permeability into a bag shape and which is filled with a culture medium; a dissociation solution bag filled with a dissociation solution containing a metal chelating agent or ornithine or a derivative thereof, and a solution sending circuit or a derivative thereof, and a solution sending circuit which connects the culture bag and the dissociation solution bag to each other and can send the dissociation solution from the dissociation solution bag to the culture bag.

Abstract: A culture system has a culture bag for suspending and culturing pluripotent stem cells in a culture medium; a waste liquid container for storing used culture medium that is connected to the culture bag; a fresh medium container for storing a fresh culture medium that is connected to the culture bag; three-way stopcocks for switching flow channels from the culture bag to the waste liquid container or the fresh culture medium container, etc.; a trap portion for trapping the pluripotent stem cells in the culture medium in the flow toward the waste liquid container side; and a filter portion for subculturing that is formed in fourth and fifth flow channels in parallel to a first flow channel. The first flow channel connects the trap part to the culture bag, and has a mesh by which a cell mass of the pluripotent stem cells can be divided. A pump is used to pump the liquid in the individual flow channels.

Abstract: Provided is a means suitable for mass culture of adherent cells and which allows easy and safe collection of the cultured adherent cells. A cell culture kit has a culture bag having flexibility, such a level of hydrophilicity that the culture of adherent cells can be achieved, and permeability into a bag shape and which is filled with a culture medium; a dissociation solution bag filled with a dissociation solution containing a metal chelating agent or ornithine or a derivative thereof, and a solution sending circuit or a derivative thereof, and a solution sending circuit which connects the culture bag and the dissociation solution bag to each other and can send the dissociation solution from the dissociation solution bag to the culture bag.

Abstract: To provide an autoserum-containing bone marrow cell culture system, whereby bone marrow cells, which are collected from a subject without using an anticoagulant, are subjected to an anticoagulation treatment using a medium in a liquid-tight state, cultured and then further cultured using the serum of said subject which is prepared in a liquid-tight state; an autoserum-containing bone marrow cell culture method; and a method for producing a medicinal composition which comprises, as the active ingredient, autoserum-containing cultured bone marrow cells. [Solution] An autoserum-containing bone marrow cell culture system for culturing bone marrow cells, which are collected from a subject without using an anticoagulant, using the serum of said subject, said system comprising a bone marrow cell suspension-storing device, a collected blood-storing device, an autoserum-acquiring device, and a bone marrow cell-culturing device.

Abstract: A package for a cryopreservation container including at least an adhesive fluoropolymer film. The package for a cryopreservation container makes it possible to store blood, rare cells and vital tissues in a very low temperature environment without any damage to the container. Further, the sealing strength resulting from heat sealing after placing a cryopreservation container in the packages is very good. Therefore, liquid nitrogen can be inhibited from entering the inside and thus contamination with bacteria, viruses or the like contained in liquid nitrogen can be avoided and the package can be prevented from being broken by expansion of intruder liquid nitrogen on the occasion of thawing. Also disclosed is a method for packaging a cryopreservation container and a method of producing a package for a cryopreservation container.

Abstract: A toner feed unit includes: a first feed portion having a first feed pipe for forming a first toner feed passage having a rectangular section and a first shutter member constructed so as to be rotatable about an axis perpendicular to the feed direction of the first toner feed passage and open and close the toner output end of the first toner feed passage; and a second feed portion having a second feed pipe for forming a second toner feed passage having a rectangular section and a second shutter member constructed so as to be rotatable about an axis perpendicular to the feed direction of the second toner feed passage and open and close the toner input end of the second toner feed passage.

Abstract: A toner cartridge has a toner storage chamber, a discharge outlet, a conveying screw, and a blocking wall. The discharge outlet serves to send out toner stored in the toner storage chamber, and the conveying screw serves to convey the toner stored in the toner storage chamber. Further, before the toner cartridge mounted into an image forming apparatus, the blocking wall is located in a space between a toner area, which is an area in the toner storage chamber where the toner exists, and the discharge outlet, thereby putting the space in a blocked state. The toner cartridge further includes a driving mechanism for, when the toner cartridge has been mounted into the image forming apparatus, driving the conveying screw by power transmitted from the image forming apparatus, so as to cancel the blocked state.

Abstract: A package for a cryopreservation container including at least an adhesive fluoropolymer film. The package for a cryopreservation container makes it possible to store blood, rare cells and vital tissues in a very low temperature environment without any damage to the container. Further, the sealing strength resulting from heat sealing after placing a cryopreservation container in the packages is very good. Therefore, liquid nitrogen can be inhibited from entering the inside and thus contamination with bacteria, viruses or the like contained in liquid nitrogen can be avoided and the package can be prevented from being broken by expansion of intruder liquid nitrogen on the occasion of thawing. Also disclosed is a method for packaging a cryopreservation container and a method of producing a package for a cryopreservation container.

Abstract: A toner feed unit includes: a first feed portion having a first feed pipe for forming a first toner feed passage having a rectangular section and a first shutter member constructed so as to be rotatable about an axis perpendicular to the feed direction of the first toner feed passage and open and close the toner output end of the first toner feed passage; and a second feed portion having a second feed pipe for forming a second toner feed passage having a rectangular section and a second shutter member constructed so as to be rotatable about an axis perpendicular to the feed direction of the second toner feed passage and open and close the toner input end of the second toner feed passage.

Abstract: Under a state where the zipper 22 of a culture bag is opened, an operator depresses the opening button 43 of an arm 40 with one finger. Consequently, a force for oscillating the arm 40 to separate a retaining portion 49 upward from the culture surface 32 around a pin 42 acts against the urging force of a leaf spring 50. Consequently, the tip 52a of an extended portion 52 ascends to a predetermined position while resisting against the urging force of the leaf spring 50. Since the lower surface 20a of the culture bag 20 is retained by a base 31 and the upper surface 20b is raised upward by the tip 52a of an extended portion 52, opening 24 of the culture bag 20 is widened. Since the width of the base 31 is larger than that of the arm 40, upper space of the culture surface 32 is not occupied by the arm 40 and a sufficiently wide work space is provided in the culture bag 20.

Abstract: An image forming apparatus includes a photoreceptor drum, a charger, an exposure device, a developing device, a toner cartridge for supplying toner to the developing device, a transfer device and a fusing device. The toner cartridge includes a toner container, a toner discharge port, a toner agitator, a toner discharger having a toner conveyor, a toner discharger partition that separates the toner container into compartments on the toner agitator side and on the toner discharger side. The toner conveyor is constructed such that its screw pitch becomes greater as it becomes more distant from the toner discharge port along the axial direction of the rotational axis of the toner discharger.

Abstract: A toner cartridge has a toner storage chamber, a discharge outlet, a conveying screw, and a blocking wall. The discharge outlet serves to send out toner stored in the toner storage chamber, and the conveying screw serves to convey the toner stored in the toner storage chamber. Further, before the toner cartridge mounted into an image forming apparatus, the blocking wall is located in a space between a toner area, which is an area in the toner storage chamber where the toner exists, and the discharge outlet, thereby putting the space in a blocked state. The toner cartridge further includes a driving mechanism for, when the toner cartridge has been mounted into the image forming apparatus, driving the conveying screw by power transmitted from the image forming apparatus, so as to cancel the blocked state.

Abstract: It is demanded that packages for cryopreservation containers which can prevent the conventional cryopreservation containers stored at very low temperatures, namely ?80 to ?196° C., from being damaged and are excellent in heat sealability be developed. The present invention provides a package for a cryopreservation container comprising at least an adhesive fluoropolymer film. The package for a cryopreservation container according to the invention makes it possible to store blood, rare cells and vital tissues in a very low temperature environment without any damage to the container. Further, the sealing strength resulting from heat sealing after placing a cryopreservation container in the packages is very good and, therefore, liquid nitrogen can be inhibited from entering the inside and thus contamination with bacteria, viruses or the like contained in liquid nitrogen can be avoided and the package can be prevented from being broken by expansion of intruder liquid nitrogen on the occasion of thawing.

Abstract: The present invention relates to a cord blood correcting device characterized by including: a branch indwelling needle having an outer cylinder needle provided on a distal end side, an inner needle drawing tube portion provided on a proximal end side, an inner needle provided inside the inner needle drawing tube portion, and a liquid outflow tube portion which branches off from the inner needle drawing tube portion; a cord tissue holder having a base portion and a holding portion for holding the cord tissue; and connecting means for interconnecting the branch indwelling needle and the cord tissue holder, and in that the connecting means has a structure for changing an angle between a puncture direction from the proximal end side to the distal end side of the branch indwelling needle and a holding direction from the base portion to the holding portion of the cord tissue holder.