Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

Abstract: The present invention provides the compound, 3-[(1S,2S)-1-[5-[(4S)-2,2-Dimethyloxan-4-yl]-2-[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-4-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carbonyl]indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one, or a pharmaceutically acceptable salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound.

Abstract: A vehicle-body front structure includes a partition wall portion which demarcates a vehicle cabin inside space, a motor arrangement portion which is formed by causing a part of the partition wall portion to bulge to an inside of a vehicle cabin and in which at least a part of a traveling motor is capable of being arranged, and a reinforcement member which extends from an upper portion of the motor arrangement portion to vehicle rear and is inclined to be positioned lower toward the vehicle rear. A rear portion of the reinforcement member is mounted on a floor panel and a lid body of a battery unit.

Abstract: A vehicle-body front structure includes a partition wall portion which demarcates a space inside a vehicle cabin, a motor arrangement portion which is formed by causing a part of the partition wall portion to bulge to an inside of the vehicle cabin and in which at least a part of a traveling motor is capable of being arranged, a reinforcement member which is inclined to be positioned lower toward vehicle rear, and a floor reinforcement which extends in a vehicle front-rear direction. A closed cross-section is configured with the motor arrangement portion, the reinforcement member, and the floor reinforcement.

Abstract: A vehicle-front body structure includes a partition wall portion which demarcates a vehicle cabin inside space, a motor arrangement portion which is formed by causing a part of the partition wall portion to bulge to an inside of a vehicle cabin and in which at least a part of a traveling motor is capable of being arranged, a cross member which is fixed to a floor panel on a vehicle rear side of the motor arrangement portion and extends in a vehicle width direction, and a reinforcement member which couples the motor arrangement portion and the cross member together.

Abstract: A vehicle-body front structure includes a partition wall portion which is provided to extend in a vehicle width direction in a vehicle front portion, a motor arrangement portion which is formed by causing a part of the partition wall portion to bulge to an inside of a vehicle cabin and in which at least a part of a traveling motor is capable of being arranged, and a reinforcement member which extends from the motor arrangement portion to vehicle rear. A rear portion of the reinforcement member is mounted on a inside-unit member which is provided in the battery unit.

Abstract: There are provided first and second loop-shaped structure sections which are provided to extend continuously along respective lower wall parts, respective right-and-left both side wall parts, and respective upper wall parts of a vehicle body so as to have a loop shape in a vehicle elevational view, respectively. The first and second loop-shaped structure sections are respectively positioned on an forward side and on a rearward side, in a vehicle longitudinal direction, of a damper support section. Each of these sections is formed by a closed-cross section portion where a closed-cross section is partitioned by plural members and/or a thick plate portion having a thicker plate thickness than a vehicle-body panel.

Abstract: The present invention provides compounds represented by formula (1) below and pharmacologically acceptable salts thereof: wherein R1, R2, R3, and R4 are as defined in the claims.

Abstract: A vehicle rear body structure improves rigidity of a portion around a wheel house while suppressing an increase in body weight (number of components) as much as possible. While a wheel house inner is provided with a second inner side reinforcement extending in a vertical direction, in a wheel house outer, a bulged section, which is formed to be bulged to a cabin outer side, includes a wheel arch-shaped section formed in an arch shape to cover a rear wheel from above when seen in a vehicle side view. The wheel house outer is formed with an upward extending ridgeline section that extends upward above the wheel arch-shaped section along a bulged shape of the bulged section to the cabin outer side and at least a portion of which overlaps the second inner side reinforcement when seen in the vehicle side view.

Abstract: A vehicle side body structure can secure a vibration-damping property of a body regardless of design specification by including a rear wheel house including a wheel house outer and a wheel house inner; a side sill extending forward from a front end of the wheel house outer; and an outer reinforcement extending in a vertical direction along a door opening edge from an intermediate portion in a front-rear direction of the wheel house outer. The wheel house outer includes: an outer overhang overhanging outward; and an outer flange extending upward from an inner end of the outer overhang. A reinforcing member is provided to cooperate with the outer overhang and the outer flange so as to define a closed cross section in a substantially triangular shape. The reinforcing member couples a rear end of the side sill and a lower end of the outer reinforcement.

Abstract: To provide a vehicle side body structure capable of securing vibration suppression performance while suppressing an increase in body weight by a connecting member that connects an outer reinforcement and an inner reinforcement. The present invention includes: a rear wheel house configured to include a wheel house outer and a wheel house inner; an outer reinforcement cooperating with the wheel house outer to define a first closed cross section that extends in a vertical direction and is provided along a part of a rear door opening edge; and an inner reinforcement cooperating with the wheel house inner to define a second closed cross section that extends in the vertical direction. A connecting member is provided to fix a striker to the outer reinforcement and connect a front flange of the outer reinforcement and each of a front wall and a front flange of the inner reinforcement.

Abstract: The vehicle body structure including an inner rein coupled to a first portion of a vibration source in a vehicle and a component constituting a vehicle body; an outer rein coupled to the component and a second portion different from the first portion of the vibration source; and a damping structure arranged between the inner rein and the outer rein and configured to dampen vibrations transmitted along the inner rein and the outer rein, wherein the inner rein includes a portion that interrupts transmission of the vibration transmitted along the inner rein, and is connected to the second reinforcing member via the damping structure.

Abstract: The present invention provides compounds represented by formula (1) below and pharmacologically acceptable salts thereof: wherein R1, R2, R3, and R4 are as defined in the claims.

Abstract: The present invention provides the compound, 3-[(1S,2S)-1-[5-[(4S)-2,2-Dimethyloxan-4-yl]-2-(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-4-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carbonyl]indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one, or a pharmaceutically acceptable salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound.

Abstract: An upper vehicle-body structure for a vehicle includes a roof rail serving as a side part of a roof of the vehicle having an internal space defined therein that extends in a generally vehicle front-rear direction, a first pillar extending downward from the roof rail, a second pillar extending downward from the roof rail at a rearward position relative to the first pillar, a roof reinforcement extending from the roof rail toward a vehicle-width-direction inner side at a rearward position relative to the first pillar, and a filler in the internal space. The filler is in contact with an inner surface of the roof rail defining the internal space and suppresses changes in shape of the roof rail. The filler is in a region extending forward and rearward relative to a front edge of a connection portion of the roof rail with the roof reinforcement.

Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

Abstract: A vehicle rear body structure improves rigidity of a portion around a wheel house while suppressing an increase in body weight (number of components) as much as possible. While a wheel house inner is provided with a second inner side reinforcement extending in a vertical direction, in a wheel house outer, a bulged section, which is formed to be bulged to a cabin outer side, includes a wheel arch-shaped section formed in an arch shape to cover a rear wheel from above when seen in a vehicle side view. The wheel house outer is formed with an upward extending ridgeline section that extends upward above the wheel arch-shaped section along a bulged shape of the bulged section to the cabin outer side and at least a portion of which overlaps the second inner side reinforcement when seen in the vehicle side view.

Abstract: A vehicle side body structure can secure a vibration-damping property of a body regardless of design specification by including a rear wheel house including a wheel house outer and a wheel house inner; a side sill extending forward from a front end of the wheel house outer; and an outer reinforcement extending in a vertical direction along a door opening edge from an intermediate portion in a front-rear direction of the wheel house outer. The wheel house outer includes: an outer overhang overhanging outward; and an outer flange extending upward from an inner end of the outer overhang. A reinforcing member is provided to cooperate with the outer overhang and the outer flange so as to define a closed cross section in a substantially triangular shape. The reinforcing member couples a rear end of the side sill and a lower end of the outer reinforcement.

Abstract: To provide a vehicle side body structure capable of securing vibration suppression performance while suppressing an increase in body weight by a connecting member that connects an outer reinforcement and an inner reinforcement. The present invention includes: a rear wheel house configured to include a wheel house outer and a wheel house inner; an outer reinforcement cooperating with the wheel house outer to define a first closed cross section that extends in a vertical direction and is provided along a part of a rear door opening edge; and an inner reinforcement cooperating with the wheel house inner to define a second closed cross section that extends in the vertical direction. A connecting member is provided to fix a striker to the outer reinforcement and connect a front flange of the outer reinforcement and each of a front wall and a front flange of the inner reinforcement.

Abstract: There are provided first and second loop-shaped structure sections which are provided to extend continuously along respective lower wall parts, respective right-and-left both side wall parts, and respective upper wall parts of a vehicle body so as to have a loop shape in a vehicle elevational view, respectively. The first and second loop-shaped structure sections are respectively positioned on an forward side and on a rearward side, in a vehicle longitudinal direction, of a damper support section. Each of these sections is formed by a closed-cross section portion where a closed-cross section is partitioned by plural members and/or a thick plate portion having a thicker plate thickness than a vehicle-body panel.