Abstract: The invention is directed to the provision of a method for generating a model for a preoperative simulation, wherein the method includes: a first step of constructing volume data for necessary organs by acquiring geometrical information from a medical image; a second step of manipulating the volume data to reposition and reorient an operator-designated organ to achieve a position and orientation appropriate for a surgical operation; a third step of generating a blood-vessel model, depicting a blood vessel to be joined to the designated organ, so as to match the position and orientation of the designated organ; a fourth step of generating volume data by forming a fat model of prescribed thickness around a prescribed organ contained in the earlier constructed volume data, after the blood-vessel model has been joined to the designated organ; a fifth step of thereafter meshing the organ represented by the generated volume data; a sixth step of manipulating a template model of a prescribed shape by using a templat

Abstract: A titanium dioxide composite is provided that can be stably dispersed in an aqueous solvent and easily administered into a living body, such as human, and allows elimination of the drug efficacy of a pharmaceutical compound supported thereon by light irradiation and a dispersion thereof. A composite is used in which a pharmaceutical compound is bound to titanium dioxide having photocatalytic activity through a hydrophilic polymer. The composite is stable in an aqueous solvent and easily administered into a living body, and adverse drug reactions of the pharmaceutical compound can be reduced by administering the composite into the body and irradiating the composite with a light to photoexcite the titanium dioxide to decompose the pharmaceutical compound in a region where the drug efficacy of the pharmaceutical composition is not required.

Abstract: Remedies/preventives for hormone-independent cancer, hormone-independent cancer cell proliferation inhibitors, apoptosis inducers for cancer cells, etc. each containing a compound having an angiotensin II antagonism, its prodrug or a salt thereof. Thus, excellent anticancer agents are provided.

Abstract: Disclosed is a titanium dioxide composite material which can be dispersed in an aqueous solvent stably and can be administered to a living body in a simple manner and in which the pharmacological effect of a therapeutic compound carried on the composite material can be eliminated by irradiation with light. Also disclosed is a dispersion product of the composite material. The composite material comprises titanium dioxide which has a photocatalytic activity and a therapeutic compound attached to the titanium dioxide through a hydrophilic polymer. The composite material is stable in an aqueous solvent and can be administered to a living body in a simple manner.

Abstract: A chromatic dispersion compensator of present invention includes a high-refractive-index VIPA plate, a three-dimensional mirror, and a control unit. The high-refractive-index VIPA plate is made of a material such as silicon having a refractive index higher than that of optical glass and is able to output incident lights toward different directions according to wavelength. The three-dimensional mirror reflects the light of each wavelength emitted from the high-refractive-index VIPA plate, at a predetermined position and returns the light to the VIPA plate. The control unit controls a temperature of the high-refractive-index VIPA plate at a constant level while controlling the position of the three-dimensional mirror corresponding to a chromatic dispersion compensation amount. Thereby, larger chromatic dispersion can be compensated while a decrease in transmission bandwidth is suppressed.

Abstract: A housing 20 is equipped for supporting, from a side, a platform of a wavelength selection device comprising an input/output port 10, a collimator 11, an expanding optical system 12, a spectroscopic element, a collecting optical system 14 and a micro electro mechanical system (MEMS) mirror array 15. Because the above noted optical member is supported from the side only, influences of a thermal expansion is limited to the height direction of the optical member and the optical axis direction. By these aspects, the influence of thermal expansion is limited to a two-dimensional from a common three-dimensional, thereby enabling a design of a countermeasure to an influence of a thermal expansion. Also, the support from the side does not create a dead space thereby making the wavelength selection device compact.

Abstract: A wavelength selective optical switch of the present invention separates a WDM light emitted from an input port of an input and output optical system, according to wavelengths, by a diffraction grating, and thereafter, condenses the lights of respective wavelengths on MEMS mirrors respectively corresponding to the respective wavelengths, in a mirror array, to reflect them by a condenser optical system, to thereby switch optical paths for the respective lights. The condenser optical system is configured by combining a plurality of lenses whose focal distances are different from each other, and positions in an optical axis direction of the lenses are adjustable by a slide mechanism. Thus, despite an error in the focal distances of the condenser lenses, in a mounting angle of a spectral element or the like, a beam pitch at the condensing positions of the lights of respective wavelengths can be coincident with a mirror pitch in the mirror array.

Abstract: In a chromatic dispersion and dispersion slope compensating apparatus according to the present invention, a WDM light which has been angularly dispersed to a first direction by a VIPA plate, is angularly dispersed to a second direction vertical to the first direction by a diffraction grating, and optical signals of respective wavelengths output from the diffraction grating are reflected by any one of a plurality of three-dimensional mirrors having reflective surfaces of curved shapes different from each other, to be returned to the VIPA plate. Thus, with a simple control mechanism in which the plurality of three-dimensional mirrors are moved to only the second direction, an apparatus capable of variably compensating for the chromatic dispersion and the dispersion slope independent of each other can be provided.

Abstract: A treatment and/or preventive agent for prostatic hypertrophy includes a compound having an antagonistic effect to an angiotensin II receptor, or a pharmaceutically acceptable salt or a prodrug thereof, as an active ingredient, wherein said compound having an antagonistic effect to an angiotensin II receptor is one or more compounds selected from the group consisting of losartan, potassium losartan, candesartan, candesartan cilexetil, balsartan, eprosartan, zolasartan, telmisartan, irbesartan, tasosartan, olmesartan medoxomil, and olmesartan.

Abstract: A housing 20 is equipped for supporting, from a side, a platform of a wavelength selection device comprising an input/output port 10, a collimator 11, an expanding optical system 12, a spectroscopic element, a collecting optical system 14 and a micro electro mechanical system (MEMS) mirror array 15. Because the above noted optical member is supported from the side only, influences of a thermal expansion is limited to the height direction of the optical member and the optical axis direction. By these aspects, the influence of thermal expansion is limited to a two-dimensional from a common three-dimensional, thereby enabling a design of a countermeasure to an influence of a thermal expansion. Also, the support from the side does not create a dead space thereby making the wavelength selection device compact.

Abstract: A wavelength selective optical switch of the present invention separates a WDM light emitted from an input port of an input and output optical system, according to wavelengths, by a diffraction grating, and thereafter, condenses the lights of respective wavelengths on MEMS mirrors respectively corresponding to the respective wavelengths, in a mirror array, to reflect them by a condenser optical system, to thereby switch optical paths for the respective lights. The condenser optical system is configured by combining a plurality of lenses whose focal distances are different from each other, and positions in an optical axis direction of the lenses are adjustable by a slide mechanism. Thus, despite an error in the focal distances of the condenser lenses, in a mounting angle of a spectral element or the like, a beam pitch at the condensing positions of the lights of respective wavelengths can be coincident with a mirror pitch in the mirror array.

Abstract: In a chromatic dispersion and dispersion slope compensating apparatus according to the present invention, a WDM light which has been angularly dispersed to a first direction by a VIPA plate, is angularly dispersed to a second direction vertical to the first direction by a diffraction grating, and optical signals of respective wavelengths output from the diffraction grating are reflected by any one of a plurality of three-dimensional mirrors having reflective surfaces of curved shapes different from each other, to be returned to the VIPA plate. Thus, with a simple control mechanism in which the plurality of three-dimensional mirrors are moved to only the second direction, an apparatus capable of variably compensating for the chromatic dispersion and the dispersion slope independent of each other can be provided.

Abstract: A chromatic dispersion compensator of present invention includes a high-refractive-index VIPA plate, a three-dimensional mirror, and a control unit. The high-refractive-index VIPA plate is made of a material such as silicon having a refractive index higher than that of optical glass and is able to output incident lights toward different directions according to wavelength. The three-dimensional mirror reflects the light of each wavelength emitted from the high-refractive-index VIPA plate, at a predetermined position and returns the light to the VIPA plate. The control unit controls a temperature of the high-refractive-index VIPA plate at a constant level while controlling the position of the three-dimensional mirror corresponding to a chromatic dispersion compensation amount. Thereby, larger chromatic dispersion can be compensated while a decrease in transmission bandwidth is suppressed.

Abstract: Remedies/preventives for hormone-independent cancer, hormone-independent cancer cell proliferation inhibitors, apoptosis inducers for cancer cells, etc. each containing a compound having an angiotensin II antagonism, its prodrug or a salt thereof. Thus, excellent anticancer agents are provided.

Abstract: A tube for medical care comprises a tube body comprising an elastomer and a photocatalyst layer containing titanium oxide and having a great number of microcracks is formed on the surface of the tube body. The tube retains elasticity, and also can secure the close contact of the elastomer surface with the photocatalyst layer and thus has a titanium oxide photocatalyst layer fixed firmly to the tube surface, due to the stress relaxation by the great number of microcracks. The tube exhibits excellent antibacterial activity due to the photocatalyst layer. The tube exhibits more excellent antibacterial activity, when another antibacterial substance is carried on the photocatalyst layer.

Abstract: An acousto-optic variable-wavelength TE/TM mode converter is configured by comprising an optical waveguide, a coupled acoustic waveguide composed of two acoustic waveguides, comb electrodes arranged at the acoustic waveguides, and surface acoustic wave absorbers arranged at the acoustic waveguide. If high-frequency electric signals having different frequencies are applied to the electrodes, surface acoustic waves W11 and W12 occur on the surface of the piezoelectric substrate, meander and propagate in the substrate, and are finally absorbed by the absorbers. The intensity distributions of the surface acoustic waves W11 and W12 are distributions where the intensity is high in a middle portion of the optical guide, and low at both ends of the optical waveguide. The peak positions of the intensities are different, and the bases of the distributions partially overlap between the two absorbers.

Abstract: The present invention relates to an optical circuit having a plurality of optical elements formed therein, and in particular, an optical circuit provided with optical waveguides that guide subsidiary light from an optical element. The optical circuit according to the invention is provided in a substrate 11 having a plurality of optical elements formed therein, with the first optical waveguide 13 that guides light to be outputted from at least one of a plurality of optical elements 12, and a second optical waveguide 14 that guides light emitted and leaking from the first optical waveguide 13.

Abstract: An acousto-optic variable-wavelength TE/TM mode converter is configured by comprising an optical waveguide, a coupled acoustic waveguide composed of two acoustic waveguides, comb electrodes arranged at the acoustic waveguides, and surface acoustic wave absorbers arranged at the acoustic waveguide. If high-frequency electric signals having different frequencies are applied to the electrodes, surface acoustic waves W11 and W12 occur on the surface of the piezoelectric substrate, meander and propagate in the substrate, and are finally absorbed by the absorbers. The intensity distributions of the surface acoustic waves W11 and W12 are distributions where the intensity is high in a middle portion of the optical guide, and low at both ends of the optical waveguide. The peak positions of the intensities are different, and the bases of the distributions partially overlap between the two absorbers.

Abstract: A multiaxial optical coupler for use in a device using an LiNbO3 substrate, which is reliable over a wide temperature range and capable of reducing coupling loss. A capillary has a plurality of linear through holes formed therethrough in a manner each inclined with respect to the central axis of the capillary such that the extension line of the central axis of the linear through hole extends through the center of a lens. A plurality of optical fibers are inserted into the linear through holes, respectively. This construction enables the optical axis of an optical beam emitted from each of the optical fibers within the capillary to pass through the center of the lens and reach the end face of a corresponding one of the optical waveguides. Similarly, the construction enables the optical axis of an optical beam emitted from the end face of each of the optical waveguides on the substrate to pass through the center of the lens and reach a corresponding one of the optical fibers within the capillary.

Abstract: An object of the invention is to provide a polarization scrambler wherein the polarization of linearly polarized signal light can be rotated to facilitate obtaining a minimum degree of polarization, and wherein scrambling operation is possible even if signal light of optional polarization states is input. Accordingly with the polarization scrambler, a polarization rotation section is provided on an input side on a chip on which is formed an optical waveguide, and a polarization scrambling section is provided on an output side. With the polarization rotation section, the polarization of linearly polarized signal light which is transmitted by the optical waveguide is rotated by means of an acousto-optic effect due to an elastic surface wave generated by an electrode, so as to become 45.degree. with respect to a vertical direction of the optical waveguide.