Abstract: The present invention provides a method of constituting a tissue construct in vitro using a tissue without depending on scaffold materials. A method of integrating a biological tissue with a vascular system in vitro, comprising coculturing a biological tissue with vascular cells and mesenchymal cells. A biological tissue which has been integrated with a vascular system by the above-described method. A method of preparing a tissue or an organ, comprising transplanting the biological tissue described above into a non-human animal and differentiating the biological tissue into a tissue or an organ in which vascular networks have been constructed. A method of regeneration or function recovery of a tissue or an organ, comprising transplanting the biological tissue described above into a human or a non-human animal and differentiating the biological tissue into a tissue or an organ in which vascular networks have been constructed.

Abstract: The present invention provides a method of constituting a tissue construct in vitro using a tissue without depending on scaffold materials. A method of integrating a biological tissue with a vascular system in vitro, comprising coculturing a biological tissue with vascular cells and mesenchymal cells. A biological tissue which has been integrated with a vascular system by the above-described method. A method of preparing a tissue or an organ, comprising transplanting the biological tissue described above into a non-human animal and differentiating the biological tissue into a tissue or an organ in which vascular networks have been constructed. A method of regeneration or function recovery of a tissue or an organ, comprising transplanting the biological tissue described above into a human or a non-human animal and differentiating the biological tissue into a tissue or an organ in which vascular networks have been constructed.

Abstract: A buckle which includes a socket and a plug. The socket includes: a cylindrical main body; a hollow part formed within the main body; a pair of left and right openings continuous to the hollow part and penetrating through wall parts of the main body; and a pair of left and right first latch surfaces defined on opening-side wall surfaces of the wall parts of the main body and inclined in a direction intersecting with an insertion direction of the plug. The plug includes: a base; arms; and a pair of left and right second latch surfaces protruding outward from outer sides of the arms and inclined in the direction intersecting with the insertion direction of the plug.

Abstract: The present invention provides a method of constituting a tissue construct in vitro using a tissue without depending on scaffold materials. A method of integrating a biological tissue with a vascular system in vitro, comprising coculturing a biological tissue with vascular cells and mesenchymal cells. A biological tissue which has been integrated with a vascular system by the above-described method. A method of preparing a tissue or an organ, comprising transplanting the biological tissue described above into a non-human animal and differentiating the biological tissue into a tissue or an organ in which vascular networks have been constructed. A method of regeneration or function recovery of a tissue or an organ, comprising transplanting the biological tissue described above into a human or a non-human animal and differentiating the biological tissue into a tissue or an organ in which vascular networks have been constructed.

Abstract: A string stopper temporarily fixing a string with enhanced firmness while having improved handleability is provided. A string stopper includes a body accommodating plural string ends, the body including a substantially cylindrical socket and a plug insertable in the socket, the socket including a string opening, a plug opening, an accommodating portion accommodating a predetermined length of the string ends, and plural securing portions securing the string ends in the accommodating portion, the plug including a base closing the plug opening, a leg integrally extending from the base and insertable in the accommodating portion and a temporarily fixing portion temporarily fixing the string ends and including first projection and second projection laterally projecting from the leg. The first projection includes two or more first projections arranged along the extending direction of the leg. The second projection faces a space between the first projections.

Abstract: A buckle which includes a socket and a plug. The socket includes: a cylindrical main body; a hollow part formed within the main body; a pair of left and right openings continuous to the hollow part and penetrating through wall parts of the main body; and a pair of left and right first latch surfaces defined on opening-side wall surfaces of the wall parts of the main body and inclined in a direction intersecting with an insertion direction of the plug. The plug includes: a base; arms; and a pair of left and right second latch surfaces protruding outward from outer sides of the arms and inclined in the direction intersecting with the insertion direction of the plug.

Abstract: There is provided a lockable buckle including a male member, a female member and a key member. A front surface portion of the female member is formed with a key member insertion hole communicating with an accommodation space. When the key member inserted into the accommodation space through the key member insertion hole is operated, the key member elastically deform engaging portions of the male member to release engagement between the engaging portions and engaged portion of the female member.

Abstract: There is provided a lockable buckle including a male member, a female member and a key member. A front surface portion of the female member is formed with a key member insertion hole communicating with an accommodation space. When the key member inserted into the accommodation space through the key member insertion hole is operated, the key member elastically deform engaging portions of the male member to release engagement between the engaging portions and engaged portion of the female member.

Abstract: A string stopper temporarily fixing a string with enhanced firmness while having improved handleability is provided. A string stopper includes a body accommodating plural string ends, the body including a substantially cylindrical socket and a plug insertable in the socket, the socket including a string opening, a plug opening, an accommodating portion accommodating a predetermined length of the string ends, and plural securing portions securing the string ends in the accommodating portion, the plug including a base closing the plug opening, a leg integrally extending from the base and insertable in the accommodating portion, and a temporarily fixing portion temporarily fixing the string ends and including first projection and second projection laterally projecting from the leg. The first projection includes two or more first projections arranged along the extending direction of the leg. The second projection faces a space between the first projections.

Abstract: A substantially cylindrical socket (10) and a plug (20) to be inserted into the socket (10) are provided. The socket includes a string opening (11), a plug opening (12), an accommodation section (13) in communication with the string opening and the plug opening, a plurality of holding sections (14) for holding string ends (1A) accommodated in the accommodation section, and a widening section (17). The plug (20) is provided with a plurality of pressing legs (24) capable of being widened toward the respective holding sections. The widening section abuts to the pressing legs when the plug is almost fully inserted into the socket (i.e. when at least substantially more than half of the plug is inserted) to press the string ends to the holding sections.

Abstract: A cord stopper (1) of the present invention includes a socket (2) and a plug (3). The plug (3) includes a pair of arms (32) and a catching section (35) arranged on facing surfaces of the pair of arms (32) to catch a cord. The catching section (35) includes a holding section (36) arranged on one of the pair of arms (32) and a pressing projection (37) arranged on the other one of the arms (32). The holding section (36) and the pressing projection (37) are arranged so as to face each other.

Abstract: Provided are a main body (10) having a first cord insertion hole (11); an operating body (20) including an accommodated portion (20A) that can be accommodated in the main body (10) and a second cord insertion hole (21) that is provided to the accommodated portion (20A) and can communicate with the first cord insertion hole (11); and an elastic body (30) biasing the operating body (20) in a direction in which the first cord insertion hole (11) is displaced from the second cord insertion hole (21) and in a direction in which the operating body (20) is protruding from the main body (10), the elastic body (30) connecting the main body (10) and the operating body (20). An elastically deformable portion (26) is provided to at least one of the accommodated portion (20A) and the main body (10). The elastically deformable portion (26) is connected to the elastic body (30) and is elastically deformed at the same time when the elastic body (30) is elastically deformed.

Abstract: A substantially cylindrical socket (10) and a plug (20) to be inserted into the socket (10) are provided. The socket includes a string opening (11), a plug opening (12), an accommodation section (13) in communication with the string opening and the plug opening, a plurality of holding sections (14) for holding string ends (1A) accommodated in the accommodation section, and a widening section (17). The plug (20) is provided with a plurality of pressing legs (24) capable of being widened toward the respective holding sections. The widening section abuts to the pressing legs when the plug is almost fully inserted into the socket (i.e. when at least substantially more than half of the plug is inserted) to press the string ends to the holding sections.

Abstract: A cord stopper (1) of the present invention includes a socket (2) and a plug (3). The plug (3) includes a pair of arms (32) and a catching section (35) arranged on facing surfaces of the pair of arms (32) to catch a cord. The catching section (35) includes a holding section (36) arranged on one of the pair of arms (32) and a pressing projection (37) arranged on the other one of the arms (32). The holding section (36) and the pressing projection (37) are arranged so as to face each other.

Abstract: An abrasive substrate is removably provided between a head portion and an abrasive member in a carry type abrasive machine. The abrasive substrate is constituted by a single synthetic resin molded member formed of the same material, and a hardness in a peripheral portion is set to be lower than that in a central portion excluding the peripheral edge portion. A difference in the hardness between the central portion and the peripheral portion is regulated by a concavo-convex surface formed on a surface at the fixing side to the head portion of the carry type abrasive machine. It is desirable that the concavo-convex surface should be constituted by a plurality of rib-shaped projections formed on the same plane. The abrasive substrate of the carry type abrasive machine can be manufactured inexpensively and can carry out a reliable and stable abrasion work.

Abstract: A first base material having a number of male engaging elements (112) formed of synthetic resin on a surface thereof and a second base material (121) are jointed and secured each other through a column-like joint portion (131). There is provided a male fixing member for sheets, which facilitates attachment operation to clothes or suspension cloths, has a durability, never loses appearance when it is mounted on clothes and allows even an infant to engage or disengage the male fixing members easily by an engagement/disengagement function of a surface fastener.

Abstract: An opening (21) for strap through which an end portion (12) of a strap (11) is inserted, an accommodation portion (23) that accommodates the end portion (12) of the strap (11) inserted through the opening (21) for strap by a predetermined length, and a pair of holding portions (40) that sandwiches and holds the strap (11) that has been accommodated in the accommodation portion (23) are formed. The pair of holding portions (40) has a substantially V-shape in which the distance between one end sides thereof is shorter than that between the other end sides thereof, and arranged in an inclined manner relative to the insertion axis (13) such that one end sides are situated nearer to the opening (21) for strap than the other end sides.