Abstract: The present invention provides a percutaneously administrable preparation comprising either an aqueous base comprising 1-menthol, a lower alcohol and an acidic buffer or water, or an oily base comprising 1-menthol, a lower alcohol and isopropyl myristate, and a cerebral function activator, for example, 2-(3-isoxazolyl)-3,6,7,9-tetrahydroimidazo[4,5-d]pyrano[4,3-b]pyridine, pharmaceutically acceptable salt or hydrate thereof.

Abstract: The present invention provides an oil preparation comprising a high lipophilic medicament such as a compound of the formula (I): 1

Abstract: After molding is started, a large reaction force is obtained by compressing the air within a lower chamber by a piston while maintained in a sealing state. At an intermediate time of the molding, a small reaction force is obtained by communicating the upper and lower chambers with each other by a switching portion of a spool. At a final time of the molding, a large reaction force is again obtained by interrupting a flow path between the upper and lower chambers. The die cushion ability can be mechanically switched in association with the stroke of the piston, the die cushion device can be set such that no time lag is easily caused at a switching time, and the die cushion ability can be instantly switched.

Abstract: A press machine having side frames which are effectively reinforced so as to appreciably reduce the noise generated during operation of the machine and improve the working accuracy of the machine without installing any special device on the outside thereof, significantly increasing the weight of the entire press machine, or obstructing a space between the side frames of the press machine. The side frames of the press machine are C-shaped in side view and are reinforced by at least one reinforcing member fixedly secured to each of the side frames at at least one predetermined place. The reinforcing members function to suppress the deformation of the opening of the C-shaped side frames to reduce noise and improve accuracy. The reinforcing members convert the vibrational energy of the side frames into heat energy which is then absorbed into the side frames.

Abstract: A press machine having side frames which are effectively reinforced so as to appreciably reduce the noise generated during operation of the machine and improve the working accuracy of the machine without installing any special device on the outside thereof or significantly increasing the weight of the entire press machine. The side frames of the press machine which are C-shaped in side view, are reinforced by at least one reinforcing member fixedly secured to each of the side frames at at least one predetermined place. The reinforcing members function to suppress the deformation of the opening of the C-shaped side frames to reduce noise and improve accuracy.

Abstract: A pouring plug adapted to be attached to a container which comprises a pourer (2) attached to a pouring port of the container, a breading blade (4) inserted in the cylindrical section of said pourer (2) and provided with a blade section confronting a film at the lower edge thereof, and a cap, (3) attached rotatably covering said cylindrical section, provided with a pipe member which is inserted in the breaking blade (3), to define opposing surfaces between the pipe member and the breaking blade, (4) one of which is equipped with a guiding section which inclines with a rising gradient in the opening rotational direction ofthe cap (3) and extends from the upper edge side to the lower edge side of the pipe member, and the other of said opposing surfaces being provided with members which are slidably in contact with said guiding inclined section, whereby the breaking blade (4) is adapted to descend upon opening rotation of the cap (3) and wherein each of said guiding inclined sections comprises up to a semicircle