Abstract: A liquid transfer device includes a monolithic trifurcated connector body defining a barrel at a first end thereof, a single IV spike at a second end thereof and a vial adapter lumen at a third end thereof. An IV port is connected to the barrel. The single IV spike has a first IV spike lumen fluidly connected at a proximal end thereof with only the vial adapter lumen via the trifurcated connector body and a second IV spike lumen fluidly connected at a proximal end thereof with only the IV port via the trifurcated connector body, thereby separating fluid communication between the vial adapter and the single IV spike from fluid communication between the IV port and the single IV spike.

Abstract: The present invention relates to rigid structures and composite materials thereof for providing radiation attenuation/shielding. Some embodiments pertain to a radiation shielding apparatus including: a plurality of positionable radiation-shielding stacks of tiles. The stacks are subsequently and adjacently arranged in a contiguous configuration. A tile positioning mechanism allows movement of tiles within a stack between a stacked (retracted) position and an extended position. In the extended position, the tiles of each of the plurality of radiation shielding stacks at least partially overlap tiles of subsequent and adjacent tile stack at corresponding opposing side-margins thereof.

Abstract: A system for inserting a pharmaceutical cartridge into a delivery device is described. The cartridge can be inserted in an arbitrary orientation and the system reorients the cartridge to a locked orientation. For example, a driver applies a torque to the cartridge to cause the reorienting. The torque rotates the cartridge around an axis thereof until the cartridge reaches the locked orientation. When the cartridge reaches the locked orientation, an interference element on the cartridge interlocks with a complementary interference element on the delivery device to lock the cartridge in the locked orientation. Once the cartridge is locked in the second orientation, the torque causes discharge the pharmaceutical.

Abstract: A method of planning the correction of spinal deformations of a subject, by performing segmentation on a three dimensional image of the subject's spine in its erect neutral position, such that the positions and orientations of the vertebrae in a region of interest are characterized. Parameters relating to the alignment and position of the vertebrae are derived from the segmentation, followed by determining whether the parameters fall within an acceptable range desired for the spine of the subject. If not within the acceptable range, an alignment optimization is performed on the vertebrae to bring the parameters within the acceptable range, to reduce the spinal deformations of the subject's spine. The alignment optimization is performed by taking into consideration limitations arising from the dynamic range of motion of the vertebrae as determined by analyzing images of the subject's spine, while the subject is in positions of maximum bending.

Abstract: An injector includes a housing and an activation button assembly movably mounted thereto and translatable from an unactuated position to an actuated position. A cartridge door is configured to receive therein a cartridge containing a substance to be dispensed, and is movably mounted to the injector housing between open and closed positions. A deflectable interference member is mounted within the injector housing and, in a resting position, blocks movement of the activation button assembly from the unactuated to the actuated position thereof. The activation button assembly is configured to activate the injector when in the actuated position, and is movable from the unactuated position to the actuated position solely upon deflection of the interference element out of the resting position thereof. The cartridge door, when in the closed position thereof and having the cartridge received therein, deflects the interference element out of the resting position thereof.

Abstract: An injector includes a housing, a needle hub movably mounted within the housing and an injection needle supported by the hub. The hub and the needle are axially translatable between retracted and injection positions. A needle shield, having an aperture, is movably connected to the housing between first and second positions. The needle extends through the needle shield aperture in the injection position of the needle and the first position of the needle shield, and the needle is blocked from extending through the needle shield aperture in the second position of the needle shield. When the needle shield is in the second position and the hub and the needle are in the injection position, the needle shield covers the tip of the needle and subsequent movement of the needle shield toward the first position axially translates the hub and the needle back toward the retracted position.

Abstract: A system is disclosed for inserting a pharmaceutical cartridge into a delivery device. Optionally the cartridge is inserted in an arbitrary orientation. Optionally, the system reorients the cartridge to a locked orientation. For example, a driver applies a torque to the cartridge to cause the reorienting. For example, said torque rotates the cartridge around an axis thereof until the cartridge reaches the locked orientation. Optionally, when the cartridge reaches the locked orientation an interference element on the cartridge interlocks with a complementary interference element on the delivery device to lock the cartridge in the locked orientation. Optionally when the cartridge is locked in the second orientation, the torque causes discharge the pharmaceutical.

Abstract: A radiation shield cover for covering a radiation shield of an X-ray system, the cover comprising cover sides; a cover bottom at the bottom of the cover sides configured to prevent contact of the radiation shield with a patient; a connection mechanism for connecting the cover to a radiation detector and/or a radiation source, and/or the radiation shield of the X-ray system; and a deployment mechanism configured to retract and/or extend the shield cover when the radiation shield retracts and/or extends, or thereafter.

Abstract: An injector includes an injection needle and an activation button assembly operatively connected to the injection needle. The activation button assembly is translatable from an unactuated position to an actuated position, the actuated position being visually different than the unactuated position. A position of the activation button assembly between the unactuated position thereof and the actuated position thereof defines a threshold point, and movement of the activation button assembly beyond the threshold point secures the activation button assembly in the actuated position, and drives the injection needle from a retracted position thereof to an injection position thereof.

Abstract: A liquid transfer device includes a barrel to fluidly connect to an infusion set, a vial adapter in communication with a vial adapter lumen and having a vial spike, and an intravenous (IV) spike to be sealingly inserted into an intravenous administration port of a container of an infusion liquid. The vial spike punctures a stopper of a vial containing a medicament. The IV spike has a first IV spike lumen fluidly connected to the vial adapter lumen and a second IV spike lumen fluidly connected to the infusion set. The liquid transfer device defines a first fluid path through the vial adapter lumen and the first IV spike lumen to introduce medicament from the vial to the container. The liquid transfer device also defines a second fluid path through the second IV spike lumen to pass the medicated infusion liquid from the container to the infusion set.

Abstract: A drug delivery device includes a compartment sized to receive a cartridge. The compartment includes a cartridge bay that opens so that a cartridge may be inserted into the cartridge bay and that closes when the cartridge is received by the compartment. The drug delivery device also includes a housing including an expanding assembly. The expanding assembly includes a driver supported from a distal end by a linear stabilizer that includes a bearing configured to push against the housing. The driver is rotated by a motor. The expanding assembly also includes two mid screws threadedly connected to the driver, a plunger driver threadedly connected to the two mid screws, and an anti-rotational guide that prevents rotation of the plunger driver.

Abstract: An alignment assembly for a cartridge interface of a drug delivery device is disclosed. The assembly optionally includes a coupling for opening fluid communication between the cartridge and the delivery device. For example, the coupling optionally includes a cannula insertable through a septum of the cartridge. The assembly may include a guide for positioning the cartridge and/or an access channel thereof within a first precision of a loaded position. The assembly optionally includes a cartridge engagement fitting (for example a gripping expander sleeve collar) attached to the coupling. Optionally when the cartridge is engaged to the fitting, the coupling is retained in connection with the access channel to within a second precision. The second precision is optionally higher than the first precision. In some embodiments one or more compliant supports movably retain the fitting oriented to engage the cartridge when the access channel is in the loaded position.

Abstract: A liquid transfer device includes a monolithic trifurcated connector body defining a barrel at a first end thereof, a single IV spike at a second end thereof and a vial adapter lumen at a third end thereof. An IV port is connected to the barrel. The single IV spike has a first IV spike lumen fluidly connected at a proximal end thereof with only the vial adapter lumen via the trifurcated connector body and a second IV spike lumen fluidly connected at a proximal end thereof with only the IV port via the trifurcated connector body, thereby separating fluid communication between the vial adapter and the single IV spike from fluid communication between the IV port and the single IV spike.

Abstract: A robotic surgical system is provided. An illustrative robotic surgical system includes a base having a known position relative to an operating table; an end effector configured to hold and align a surgical tool for performing a procedure on a subject on said operating table; at least one robotic arm connecting said base with said end effector; and a target attached to the end effector, wherein an image of the target attached to the end effector is used to determine a pose of the end effector.

Abstract: A method and assembly are disclosed for interfacing between a drug cartridge and a drug delivery device. Optionally, the drug delivery device includes a compartment that retains the cartridge during drug delivery and/or a stopper pushing assembly mounted to the device behind (proximal to) the compartment. In some embodiments, the cartridge may be inserted laterally into the compartment in front of the pushing assembly. For example, the delivery device may include a moving cartridge bay. The cartridge is optionally inserted into the bay and/or the bay and cartridge optionally move into the cartridge compartment. Alternatively or additionally, the cartridge compartment may have a proximal opening into which the cartridge is inserted and/or the pushing assembly may be moved into position after insertion of the cartridge. In some embodiments the cartridge may have a distal seal that is broken by a longitudinal movement.

Abstract: A measurement system is presented configured for integration with a processing equipment for applying optical measurements to a structure.

Abstract: An electronic injector including a needle insertion assembly configured to move a needle in an insertion direction from a first needle position where the needle is above the surface of a patient's skin to a second needle position where the needle pierces the patient's skin. The injector further includes a member mechanically coupled to the needle and configured to move when the needle. The injector further includes an optical detector having a generally planar detection surface and configured to detect movement of the member based on a change in a transverse projection of the member onto the detection surface and output a signal based on the change in the transverse projection. Additional, a processor is configured to determine the position of the needle based on the output signal, and the transverse projection of the member changes when the needle moves.

Abstract: In some embodiments a system and method are described for safeguarding a hazard. The hazard, for example a needle point, may be moved between a protected retracted position, an active extended position and/or an intermediate position. Optionally in the retracted position, the hazard may be protected inside a housing. Optionally in the extended position, the hazard may be exposed. Optionally, in the intermediate position the hazard may be partially protected and/or concealed, for example by a shield and/or in an indentation. In some embodiments, compromising a shield causes the hazard to be retracted to the retracted position.