Abstract: The present application relates to a digested DDIT4L product as a diagnostic marker for Alzheimer's disease, and use thereof in diagnosing Alzheimer's disease. In particular, the present application relates to use of a substance for detecting a digested intron retention (DIR) product encoding DNA-damage-inducible transcript 4 like (DDIT4L) in a sample of a subject in preparing a product for diagnosing Alzheimer's disease or a mild cognitive disorder and/or assessing (e.g., grading or staging) cognitive disorder progression, a related product thereof, and a method for screening a medicament using the DIR product.

Abstract: An all-optical neural network that utilizes light beams and optical components to implement layers of the neural network is disclosed herein. The all-optical neural network includes an input layer, zero or more hidden layers, and an output layer. Each layer of the neural network is configured to simulate linear and nonlinear operations of a conventional artificial neural network neuron on an optical signal. In an embodiment, the optical linear operation is performed by a spatial light modulator and an optical lens. The optical lens performs a Fourier transformation on the set of light beams and sums light beams with similar propagation orientations. The optical nonlinear operation is implemented utilizing a nonlinear optical medium having an electromagnetically induced transparency characteristic whose transmission of a probe beam of light is controlled by the intermediate output of a coupling beam of light from the optical linear operation.

Abstract: A volume measurement method includes: receiving multiple pulse signals when a device under test (DUT) starts passing through a sensing gate; recording multiple X-axis values corresponding to multiple positions of the DUT in response to each pulse signal, and reading the multiple sensing data to calculate a Y-axis value and a Z-axis value corresponding to each X-axis value, wherein the multiple sensing data is obtained by sensing the DUT through the sensing gate; recording a maximum X-axis value corresponding to a final position of the DUT in response to a final pulse signal when the DUT finishes passing through the sensing gate; setting the maximum of the multiple Y-axis values corresponding to the multiple X-axis values as a maximum Y-axis value, and setting the maximum of the multiple Z-axis values corresponding to the multiple X-axis values as a maximum Z-axis value; and calculating a volume of the DUT based on the maximum X-axis value, the maximum Y-axis value and the maximum Z-axis value.

Abstract: A method and device for issuing an identity certificate to a blockchain node in a blockchain network includes issuing a first identity certificate to a first terminal. a second identity certificate issuance request that is from the first terminal and that is made by using the first identity certificate is received and a second identity certificate is issued to the first terminal, which forwards the second identity certificate to a second terminal. A third identity certificate issuance request that is from the second terminal and that is made by using the second identity certificate is received and a third identity certificate is issued to the second terminal, which forwards the third identity certificate to a third terminal.

Abstract: A capacitive coupling package structure includes a first package member, a second package member, a first conductive component, a second conductive component, a first chip, and a second chip. The first package member has two first sides and two second sides that are opposite and connected to the two first sides. The first package member is covered by the second package member. The first conductive component and the second conductive component are disposed in the first package member. Portions of the first conductive component and the second conductive component extend through the two first sides to the outside of the second package member. Other portions of the first conductive component and the second conductive component are flush with the two second sides. The first chip and the second chip establish a capacitive coupling relationship through the first conductive component and the second conductive component.

Abstract: Various embodiments for deduplication of APIs using similarity measures and artificial intelligence are described herein. An embodiment operates by receiving a request to compare a first computing program to a second computing program, wherein each computing program includes an address, one or more tables accessed by a respective computing program, one or more input parameters, and one or more output parameters. Similarity measures are calculated between the addresses, tables, input parameters, and output parameters of the two computing programs. The similarity measures are provided to a trained artificial intelligence (AI) model, which generates a similarity determination. Performed an action based on the similarity determination.

Abstract: Disclosed herein are system, method, and computer program product embodiments for hybrid-type authorization. An embodiment operates by parsing a policy expression into an abstract syntax tree (AST) and receiving, from a local server, user attribute data of a user. The embodiment further operates by traversing the AST to evaluate the user attribute data and determining whether a result of the traversing is indeterminate. In addition the embodiment operates by sending, to a remote server, a request for additional user attribute data in response to determining that the result is indeterminate, and receiving, from the remote server, the additional user attribute data. Then the embodiment operates by re-traversing the AST to evaluate the user attribute data and the additional user attribute data, authorizing the user based on at least one of the traversing or re-traversing, and outputting an authorization result.

Abstract: An electronic device includes a housing mechanism defining an accommodating chamber, a circuit board assembly accommodated in the accommodating chamber, and an anti-disassembly mechanism. The circuit board assembly includes a substrate and a controller connected to the substrate, and the substrate includes a magnetic attraction area. The anti-disassembly mechanism includes a light sensor configured to detect a light intensity in the accommodating chamber, an electromagnetic element opposite to the magnetic attraction area, and an elastic element resisting between the electromagnetic element and the substrate. When the light intensity signal is less than or equal to the light intensity threshold, the controller controls the electromagnetic element to be powered on to generate magnetic attraction to the magnetic attraction area, so that the electromagnetic element is attracted to the magnetic attraction area.

Abstract: A partition-based method to implement idempotence in an event-driven architecture is provided, which acts to reduce the pressure of database reading and writing, thus improving the performance of event handling. In order to improve parallelism, a consumer cluster (a cluster of multiple consumers that can share the responsibility of processing events) is established such that the events are distributed among different partitions within the cluster. Each partition contains a different consumer worker (with its own cache). An event dispatch module is then used to dispatch events among the consumer workers in a way that keeps the load balanced. In an example embodiment, this is performed by generating a partition identification for an event based on a hash of the context identification of the session established between the user and the application when the event was generated, followed by a modulo operation based on the number of consumer workers in the cluster.

Abstract: This application provides a method for detecting margins of a data signal. A receive end of a data signal may adjust a voltage of a reference power source; adjust, based on a plurality of reference moments included in a reference moment set, a moment of an edge of a data strobe signal transmitted by a transmit end of the data signal; and during the adjustment, for each reference voltage and each reference moment, determine whether a bit error exists in data obtained by decoding the data signal when the voltage of the reference power source is the reference voltage and the moment of the edge of the data strobe signal is the reference moment, to obtain a timing margin of the data signal at each reference voltage and a voltage margin of the data signal at each reference moment.

Abstract: Embodiments herein relate to a temperature-sensing circuit for a semiconductor device. The circuit has a remote temperature-sensing element (RTSE) including a metal thermistor formed in a metal layer on the front side or backside of a substrate. The metal thermistor may be serpentine or spiral shaped. The RTSE communicates with a separate sense circuit at another location such as on the substrate. The RTSE can further include a thin film resistor (TFR) in an adjacent dielectric layer of the stack or within the sense circuit. The RTSE is driven alternately at opposing ends to cancel out the effects of power supply variations. An output voltage which represents a sensed temperature is obtained from a point between the metal thermistor and the TFR for processing by an analog-to-digital converter.

Abstract: A low power hybrid reverse (LPHR) bandgap reference (BGR) and digital temperature sensor (DTS) or a digital thermometer, which utilizes subthreshold metal oxide semiconductor (MOS) transistors.

Abstract: The present invention continuously generates a signal at an acceptable frequency without utilizing the PLL to modify the operation of the VCO. When the VCO is initialized properly to output a signal at a specific frequency, the VCO operates on its own to continuously output signals, and the VCO state is modified at regular intervals. Thus, when the interval is short enough and when the VCO is modified to the initial state every time, the VCO state will not deviate significantly from the initial state during these intervals. Thus, the VCO continuously generate signals with frequencies acceptably closed to the specific frequency. That is to say, the invention utilizes the injection lock to modify the operation of the VCO. To compare with the convention skills utilizing the PLL which has to feed back the signal generated by the VCO to the PLL for modifying the VCO state dynamically, the utilization of the injection lock simplifies the hardware and streamlines the process.

Abstract: The present disclosure relates to semiconductor structures and, more particularly, to electrostatic discharge (ESD) devices and methods of manufacture. The structure (ESD device) includes: a bipolar transistor comprising a collector region, an emitter region and a base region; and a lateral ballasting resistance comprising semiconductor material adjacent to the collector region.

Abstract: Methods, systems, and computer-readable storage media for receiving a key and a value of a data object, determining a first identifier and a second identifier based on the key, defining an entry object including the first identifier, the second identifier, and the value, and storing the entry object in a hashmap by: determining a first value of a first index based on the first identifier, determining a second value of a second index to provide a first value and second value pair that defines a first location within the hashmap storing the first identifier, determining a third value of a third index for the first value and second value pair, where the first value, the second value, and the third value define a second location within the hashmap storing the second identifier, and storing the value at a third location within the hashmap.

Abstract: The present disclosure provides a TCR-T cell for tumor-killing, wherein the TCR-T cell is a T cell carrying a TCR that recognizes a tumor antigen, and the TCR in the TCR-T cell is derived from any one or more of the following T cells: 1) a CD4 T cell expressing one or more of TNFRSF18, CXCL13, TNFRSF4, TNFSF8, ENTPD1, ACP5, LAYN, TNFRSF9, CTLA4, CD200 and TIGIT genes in the tumor; and 2) a CD8 T cell expressing one or more of TNFRSF18, CXCL13, CXCR6, GALNT2, ENTPD1, ACP5, HAVCR2, LAYN, TNFRSF9, CTLA4 and CD109 genes in the tumor. The TCR-T cell according to the present disclosure can be effectively applied to the treatment of a tumor, especially in an immunotherapy.