Patents by Inventor Youssef Biadillah

Youssef Biadillah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11207176
    Abstract: Some embodiments of the present disclosure provide a stent-valve for transcatheter implantation to replace a cardiac valve. In some embodiments, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation. In some embodiments, the stent-valve comprises a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprising material that swells in response to contact with blood or components thereof.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: December 28, 2021
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Publication number: 20210322159
    Abstract: Some embodiments of the present disclosure provide a stent-valve for transcatheter implantation to replace a cardiac valve. In some embodiments, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation. In some embodiments, the stent-valve comprises a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprising material that swells in response to contact with blood or components thereof.
    Type: Application
    Filed: May 18, 2021
    Publication date: October 21, 2021
    Applicant: BOSTON SCIENTIFIC LIMITED
    Inventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Publication number: 20210290379
    Abstract: Various embodiments of a seal for a stent-valve, and methods of production, are described. In some embodiments, the seal or a skirt comprises a fabric wall portion and a polymeric material fused to the fabric wall portion, the polymeric material having a melting temperature that is lower than that of the fabric wall portion. The fibres of the fabric may remain unmelted at the interface with the polymeric material, the polymeric material being attached to material to the fibres of the fabric wall portion by fusion. The polymeric material may provide a welded joint to another fabric wall portion and/or may reinforce the fabric and/or may occlude pores of the fabric.
    Type: Application
    Filed: June 8, 2021
    Publication date: September 23, 2021
    Applicant: Boston Scientific Limited
    Inventors: Lionel Flaction, Stephane Delaloye, Youssef Biadillah, Arnaud Humair
  • Patent number: 11045312
    Abstract: Various embodiments of a seal for a stent-valve, and methods of production, are described. In some embodiments, the seal or a skirt comprises a fabric wall portion and a polymeric material fused to the fabric wall portion, the polymeric material having a melting temperature that is lower than that of the fabric wall portion. The fibres of the fabric may remain unmelted at the interface with the polymeric material, the polymeric material being attached to material to the fibres of the fabric wall portion by fusion. The polymeric material may provide a welded joint to another fabric wall portion and/or may reinforce the fabric and/or may occlude pores of the fabric.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: June 29, 2021
    Assignee: Boston Scientific Limited
    Inventors: Lionel Flaction, St├ęphane Delaloye, Youssef Biadillah, Arnaud Humair
  • Patent number: 11002646
    Abstract: The disclosure relates to devices, solutions and methods for collecting and processing samples of bodily fluids containing cells (as well as embodiments for the collection, and processing and/or analysis of other fluids including toxic and/or hazardous substances/fluids). In addition, the disclosure relates generally to function genomic studies and to the isolation and preservation of cells from saliva and other bodily fluids (e.g., urine), for cellular analysis. With respect to devices for collection of bodily fluids, some embodiments include two mating bodies, a cap and a tube (for example), where, in some embodiments, the cap includes a closed interior space for holding a sample preservative solution and mates with the tube to constitute the (closed) sample collection device. Upon mating, the preservation solution flows into the closed interior space to preserve cells in the bodily fluid. The tube is configured to receive a donor sample of bodily fluid (e.g.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: May 11, 2021
    Assignee: DNA GENOTEK, INC.
    Inventors: Youssef Biadillah, Stephen D. Andrews
  • Publication number: 20210068949
    Abstract: A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.
    Type: Application
    Filed: November 17, 2020
    Publication date: March 11, 2021
    Applicant: Symetis SA
    Inventors: Youssef Biadillah, Stephane Delaloye, Fabien Lombardi, Jean-Luc Hefti
  • Publication number: 20210038210
    Abstract: Applicator for depositing a layer of adhesive or sealant composition on a target site of a biological and/or prosthetic tissue, the applicator including a body having an application face intended to be positioned facing the biological and/or prosthetic tissue, and having a first outlet opening provided in the application face, the first outlet opening being shaped as a slot for allowing the adhesive or sealant composition to flow out of the applicator and to form the layer of adhesive or sealant composition, a second inlet opening provided in the application face, adjacent the first outlet opening, for allowing pollutants or undesirable elements to be removed from the target site while depositing the layer of adhesive or sealant composition, wherein the first outlet opening has a first section and the second inlet opening has a second section, the second section being greater than the first section.
    Type: Application
    Filed: April 24, 2019
    Publication date: February 11, 2021
    Applicant: Tissium
    Inventors: Julien Lamazouade, Miguel Lopes, Simon Menand, Youssef Biadillah, Maria Pereira
  • Patent number: 10898321
    Abstract: A stent-valve for transcatheter implantation to replace a cardiac valve, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation, the stent-valve comprising a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprises material that swells in response to contact with blood. In some embodiments, the seal comprises a flap or pocket that is distensible in response to backpressure and/or paravalve back-flow of blood.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: January 26, 2021
    Assignee: Symetis SA
    Inventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Publication number: 20200398267
    Abstract: Some embodiments are directed to a bodily fluid sample collection device for the collection of naturally expressed bodily fluids and include a cap engageable with a tube to close a mouth of the tube. The cap includes a chamber for containing a reagent. The tube defines at least partly a sample collection space for receiving the naturally expressed bodily fluid. The cap comprises first and second cap portions relatively movable with respect to each other. The first and second cap portions are configured such that, responsive to engagement of the cap on the tube, one of the cap portions is caused to move integrally relative to the other cap portion to open the chamber and permit fluid communication between the chamber and the sample collection space. The reagent in the chamber is thereby permitted to mix with the bodily fluid in the sample collection space. A method of organizing and processing samples is also described.
    Type: Application
    Filed: January 21, 2020
    Publication date: December 24, 2020
    Applicant: AboGen, Inc.
    Inventors: Youssef BIADILLAH, Stephen ANDREWS, Bryce G. RUTTER, Melvin J. LEEDLE, Jonathan SUNDY, Benjamin Cooper PRIESS, Chris BRIDEN
  • Patent number: 10869760
    Abstract: A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: December 22, 2020
    Assignee: Symetis SA
    Inventors: Youssef Biadillah, Stephane Delaloye, Fabien Lombardi, Jean-Luc Hefti
  • Publication number: 20200284704
    Abstract: The disclosure relates to devices, solutions and methods for collecting and processing samples of bodily fluids containing cells (as well as embodiments for the collection, and processing and/or analysis of other fluids including toxic and/or hazardous substances/fluids). In addition, the disclosure relates generally to function genomic studies and to the isolation and preservation of cells from saliva and other bodily fluids (e.g., urine), for cellular analysis. With respect to devices for collection of bodily fluids, some embodiments include two mating bodies, a cap and a tube (for example), where, in some embodiments, the cap includes a closed interior space for holding a sample preservative solution and mates with the tube to constitute the (closed) sample collection device. Upon mating, the preservation solution flows into the closed interior space to preserve cells in the bodily fluid. The tube is configured to receive a donor sample of bodily fluid (e.g.
    Type: Application
    Filed: May 20, 2020
    Publication date: September 10, 2020
    Inventors: Youssef BIADILLAH, Stephen D. ANDREWS
  • Publication number: 20200205971
    Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.
    Type: Application
    Filed: February 26, 2020
    Publication date: July 2, 2020
    Applicant: Symetis SA
    Inventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stephane Delaloye
  • Patent number: 10695175
    Abstract: A guide catheter is described for introduction into a patient's vasculature, to provide a substantially continuous guide lumen within the vasculature to the ascending aorta, through which one or more other functional catheters may be introduced and removed during the procedure. The guide catheter includes an aligner at its distal region for aligning the position and/or inclination of the distal region of the guide catheter with respect to the ascending aorta. The aligner includes an embolic protection filter. The guide catheter is made of material collapsible/distensible in cross section to adopt a small shape when no catheter is present inside, and to distend to a large shape to accommodate passage of functional catheter therethrough. The cross-section shape collapses/distends by folding/unfolding of material without elastic stretching of the material.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: June 30, 2020
    Assignee: Boston Scientific Limited
    Inventors: Stephane Delaloye, Jean-Luc Hefti, Youssef Biadillah
  • Patent number: 10682228
    Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: June 16, 2020
    Assignee: Symetis SA
    Inventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stephane Delaloye
  • Publication number: 20200138570
    Abstract: The invention relates to a heart implant, particularly being configured to reduce or eliminate a heart valve insufficiency after implantation into the heart, comprising a closure element (1) being configured to be positioned within the heart valve annulus, particularly being configured to close or at least to reduce a remaining gap between closing valve leaflets, an anchoring element (2) being attached to the closure element (1) for fixing the implant in the heart, preferably for non-invasive fixing by surface contact between the exterior surface of the anchoring element (2) and an interior surface of a heart lumen, preferably the atrium, wherein the closure element (1) and the anchoring element (2) are connected with a means (1a, 2a) for changing the relative position of the closure element (1) and the anchoring element (2) to each other. The invention furthermore relates to a method of treating a heart valve insufficiency.
    Type: Application
    Filed: January 9, 2020
    Publication date: May 7, 2020
    Applicant: coramaze technologies GmbH
    Inventors: Youssef BIADILLAH, Laura FIGULLA, Stefan Daniel MENZL, Thomas GERHARDT, Niklas Maximilian NATHE, Raz BAR-ON, Leah KIDNEY, Mario HEINTZE
  • Publication number: 20200069422
    Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, and associated methods and systems for their delivery via minimally-invasive surgery.
    Type: Application
    Filed: July 2, 2019
    Publication date: March 5, 2020
    Applicant: Symetis SA
    Inventors: JACQUES ESSINGER, STEPHANE DELALOYE, JEAN-LUC HEFTI, YOUSSEF BIADILLAH, LUC MANTANUS, IKER MALLABIABARRENA, REYNALD PASSERINI, MICHAEL PARIS, FABIEN LOMBARDI
  • Patent number: 10576468
    Abstract: Some embodiments are directed to a bodily fluid sample collection device for the collection of naturally expressed bodily fluids and include a cap engageable with a tube to close a mouth of the tube. The cap includes a chamber for containing a reagent. The tube defines at least partly a sample collection space for receiving the naturally expressed bodily fluid. The cap comprises first and second cap portions relatively movable with respect to each other. The first and second cap portions are configured such that, responsive to engagement of the cap on the tube, one of the cap portions is caused to move integrally relative to the other cap portion to open the chamber and permit fluid communication between the chamber and the sample collection space. The reagent in the chamber is thereby permitted to mix with the bodily fluid in the sample collection space. A method of organizing and processing samples is also described.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: March 3, 2020
    Assignee: ABOGEN, INC.
    Inventors: Youssef Biadillah, Stephen Andrews, Bryce G. Rutter, Melvin J. Leedle, Jonathan Sundy, Benjamin Cooper Priess, Chris Briden
  • Patent number: 10531953
    Abstract: A delivery apparatus for delivering a stent-valve for implantation within the body, the delivery apparatus configured for introduction into the body through an arterial introducer of a type having a stem insertable into the body and a mouth section that remains outside the body, the mouth section including a haemostasis valve, and wherein the delivery apparatus comprises: a first constraining sheath at a stent-valve accommodation region of the apparatus at a distal end of the apparatus, and configured for constraining at least a portion of a stent-valve at the accommodation region in a radially collapsed configuration; a delivery introducer captive on the delivery apparatus, and slidable between a first position surrounding at least a portion of the stent-valve accommodation region, and a second position in which the delivery introducer slides proximally of the stent-valve accommodation region; wherein the delivery introducer is insertable at least partly into the mouth of a said arterial introducer, the deli
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: January 14, 2020
    Assignee: SYMETIS SA
    Inventors: Fabien Lombardi, Jacques Essinger, St├ęphane Delaloye, Jean-Luc Hefti, Luc Mantanus, Youssef Biadillah, Pierre Simonin
  • Publication number: 20190336278
    Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, and associated methods and systems for their delivery via minimally-invasive surgery.
    Type: Application
    Filed: July 15, 2019
    Publication date: November 7, 2019
    Applicant: Symetis SA
    Inventors: JACQUES ESSINGER, YOUSSEF BIADILLAH, STEPHANE DELALOYE, JEAN-LUC HEFTI, LUC MANTANUS, REYNALD PASSERINI
  • Publication number: 20190314151
    Abstract: A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.
    Type: Application
    Filed: February 11, 2019
    Publication date: October 17, 2019
    Applicant: Symetis SA
    Inventors: Youssef Biadillah, Stephane Delaloye, Fabien Lombardi, Jean-Luc Hefti