Abstract: The present invention discloses a method for preparing sucralose-6-acetate in a biphasic liquid-liquid system. The method comprises slowly dropwise adding an inert non-polar solvent containing a chlorinating agent to an N,N-dimethyl formamide (DMF) solution of sucrose-6-acetate; then reacting the biphasic liquid-liquid mixture at a certain temperature for 9-20 hours; cooling the system to room temperature after stopping heating, and settling the solution to form layers, an upper layer being an inert non-polar solvent layer, and a lower layer being a DMF solution layer containing the product; hydrolyzing, neutralizing, and filtering the lower layer to obtain a filtrate, and then concentrating the filtrate to obtain a concentrate; dissolving the concentrate in water, and obtaining the product by extraction using ethyl acetate and crystallization, the inert non-polar solvent being an alkane solvent containing 8-18 carbon atoms that is not mutually soluble with DMF.

Abstract: A method and system for reducing Nyquist ghost artifact is provide. The method may include: obtaining a plurality of measured data sets; determining, based on the plurality of measured data sets, in a data space, a plurality of convolution kernels, each convolution kernel relating to all of the plurality of measured data sets; generating, based on the plurality of convolution kernels and the plurality of measured data sets, in the data space, a plurality of synthetic data sets; generating, based on the plurality of synthetic data sets and the plurality of measured data sets, in the data space, a plurality of combined data sets, each combined data set relating to one of the plurality of synthetic data sets and a corresponding measured data set of the plurality of measured data sets; and reconstructing, based on the plurality of combined data sets, an image.

Abstract: A method and system for image reconstruction are provided. Multiple coil images may be obtained. A first reconstructed image based on the multiple coil images may be reconstructed based on a first reconstruction algorithm. A second reconstructed image based on the multiple coil images may be reconstructed based on a second reconstruction algorithm. Correction information about the first reconstructed image may be generated based on the first reconstructed image and the second reconstructed image. A third reconstructed image may be generated based on the first reconstructed image and the correction information about the first reconstructed image.

Abstract: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.

Abstract: The disclosure relates to a system and method for image reconstruction. The method may include the steps of: obtaining raw data corresponding to radiation rays within a volume, determining a radiation ray passing a plurality of voxels, grouping the voxels into a plurality of subsets such that at least some subset of voxels are sequentially loaded into a memory, and performing a calculation relating to the sequentially loaded voxels. The radiation ray may be determined based on the raw data. The calculation may be performed by a plurality of processing threads in a parallel hardware architecture. A processing thread may correspond to a subset of voxels.

Abstract: A method and system for image reconstruction are provided. Multiple coil images may be obtained. A first reconstructed image based on the multiple coil images may be reconstructed based on a first reconstruction algorithm. A second reconstructed image based on the multiple coil images may be reconstructed based on a second reconstruction algorithm. Correction information about the first reconstructed image may be generated based on the first reconstructed image and the second reconstructed image. A third reconstructed image may be generated based on the first reconstructed image and the correction information about the first reconstructed image.

Abstract: Systems and methods for estimating complex transmit field B1+ a transmit coil of a magnetic resonance imaging (MRI) system in both k-space and image domains are described herein. Estimating complex RF field B1+ in the k-space domain includes acquiring complex data in a k-space domain, estimating a complex B1+ map in the k-space domain of a transmit coil and storing the complex B1+ map. The complex B1+ map can be estimated based on the complex images. Estimating complex transmit field B1+ in the image domain includes acquiring at least two complex images in a k-space domain, transforming the complex images into an image domain, estimating a complex B1+ map in the image domain of a transmit coil, and storing the complex B1+ map.

Abstract: The disclosure relates to a system and method for correcting inhomogeneity in an MRI image. The method may include the steps of: acquiring a first set of k-space data, acquiring a second set of k-space data, generating the convolution kernel of the first set of k-space data based on the first set of k-space data and the second set of k-space data, performing inverse Fourier transform on the convolution kernel of the first set of k-space data to obtain an inversely transformed convolution kernel of the first set of k-space data, and generating a corrector based on the inversely transformed convolution kernel of the first set of k-space data. The method may be implemented on a machine including at least one processor and storage.

Abstract: The disclosure relates to a system and method for generating or using a synthesizing filter in image reconstruction. The method may include: acquiring a calibration data set including a plurality of data points, determining a first calibration region in the calibration data set, the first calibration region including a matrix having a plurality of data points, the plurality of data points includes a first data point at the center of the first calibration region, constructing a first relationship between the first data point and the data points in the first calibration region, and generating a synthesizing filter based on the first relationship. The first data point is at the center of the first calibration region. The method may be implemented on at least one machine each of which has at least one processor and storage. The generated synthesizing filter may be stored in the storage in electronic form as a data file.

Abstract: A method for improving the signal-to-noise ratio (SNR) of TGRAPPA. The SNR of the ACS lines is proportional to the condition number of the GRAPPA kernel encoding equations. Therefore, the GRAPPA kernel estimated from higher SNR ACS lines amplifies the random noise in GRAPPA reconstruction. In TGRAPPA reconstruction of dynamic image series, a widely used method to acquire ACS lines is to average-all-frame (AAF). The present disclosure utilizes a tile-all-frame (TAF) as ACS lines to improve the SNR of the reconstructed images.

Abstract: A system and method for magnetic resonance imaging is provided. The method includes acquiring a first set of MR signals and a second set of MR signals by applying a pulse sequence on a subject. The method also includes obtaining a first data line by filling the first set of MR signals into k-space along a first trajectory, and obtaining a second data line by filling the second set of MR signals into k-space along a second trajectory. The method also includes determining a candidate k-space shift based on the first data line and the second data line, and determining a candidate gradient delay based on the candidate k-space shift obtained in each of a plurality of iterations. The method also includes reconstructing an image of the subject based on the candidate gradient delay obtained in the last iteration.

Abstract: The disclosure relates to a system and method for image reconstruction. The method may include the steps of: obtaining raw data corresponding to radiation rays within a volume, determining a radiation ray passing a plurality of voxels, grouping the voxels into a plurality of subsets such that at least some subset of voxels are sequentially loaded into a memory, and performing a calculation relating to the sequentially loaded voxels. The radiation ray may be determined based on the raw data. The calculation may be performed by a plurality of processing threads in a parallel hardware architecture. A processing thread may correspond to a subset of voxels.

Abstract: The present disclosure discloses a method, an apparatus and a system for device identification. A specific implementation of the method comprises: receiving a device identification request sent from a terminal device, the device identification request comprising a current user identifier of a current user of the terminal device; acquiring a public key in a preset asymmetric key pair to serve as a first public key; sending the first public key and a randomly-generated first random number to the terminal device; receiving device characteristic information sent from the terminal device, the device characteristic information being generated by the terminal device based on the current user identifier, the first public key, the first random number and a device identifier of the terminal device; and identifying the terminal device based on the current user identifier, the first random number and the device characteristic information.

Abstract: A method and system for image reconstruction are provided. Multiple coil images may be obtained. A first reconstructed image based on the multiple coil images may be reconstructed based on a first reconstruction algorithm. A second reconstructed image based on the multiple coil images may be reconstructed based on a second reconstruction algorithm. Correction information about the first reconstructed image may be generated based on the first reconstructed image and the second reconstructed image. A third reconstructed image may be generated based on the first reconstructed image and the correction information about the first reconstructed image.

Abstract: A pseudo-random, incoherent sampling technique, called Variable density Incoherent Spatiotemporal Acquisition (VISTA) is disclosed, which is based on minimal Riesz energy problem. Compared with other pseudorandom methods (e.g., PDS), VISTA has the unique ability to incorporate a variety of problem-specific constraints. In this study, VISTA was applied to real-time CMR, where it not only provided an incoherent sampling with variable density but also ensured a constant temporal resolution and a fully sampled time-averaged data.

Abstract: A method for switching an audio output device includes after a predetermined event is captured on the information output interface, detecting whether a voice interface object representing a voice message is currently displayed on the information output interface. The method further includes detecting whether an external audio output device is currently connected to the mobile electronic apparatus. If it is detected that a voice interface object is currently displayed, and it is not detected that an external audio output device is connected to the mobile electronic apparatus, displaying an interface switching object on the information output interface, to correspondingly switch an audio output device of the mobile electronic apparatus according to an input operation of a user.

Abstract: An optically diffusive plastic can comprise 40 to 94.9 mass % of a polymer resin matrix; 5 to 50 mass % of a glass filler; and 0.1 to 10 mass % of a light diffusing component; wherein the difference between refractive index of the polymer resin matrix and refractive index of the glass filler is less than or equal to 0.02; wherein a 1 millimeter (mm) thick sample of the optically diffusive plastic comprises a DLD value of greater than or equal to 1 degree (°) as measured by goniophotometry; wherein the 1 mm thick sample comprises a total transmittance of greater than or equal to 40% for incident light having a wavelength of 360 nanometers (nm) to 750 nm in air; and wherein a 3.2 mm thick sample of the optically diffusive plastic comprises a flexural modulus, measured at 23° C., of greater than or equal to 2,500 Megapascal (MPa).

Abstract: A system and method for image reconstruction are provided. A first region of an object may be determined. The first region may correspond to a first voxel. A second region of the object may be determined. The second region may correspond to a second voxel. Scan data of the object may be acquired. A first regional image may be reoncstrcted based on the scan data. The reconstruction of the first regional image may include a forward projection on the first voxel and the second voxel and a back projection on the first voxel.

Abstract: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.

Abstract: The embodiments herein relate to methods and apparatus for electroplating one or more materials onto a substrate. Typically, the embodiments herein utilize a channeled plate positioned near the substrate, creating a cross flow manifold between the channeled plate and substrate, and on the sides by a flow confinement ring. A seal may be provided between the bottom surface of a substrate holder and the top surface of an element below the substrate holder (e.g., the flow confinement ring). During plating, the apparatus may switch between a sealed state and an unsealed state, for example by lowering and lifting the substrate and substrate holder as appropriate to engage and disengage the seal. A higher level of applied current or applied voltage may be provided to the substrate when the apparatus is in the sealed state compared to the unsealed state.