Patents by Inventor Yu-Hsiang Chang

Yu-Hsiang Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10538739
    Abstract: The invention provides a chimeric receptor comprising NKG2D, DAP10 and CD3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of NK cells. The invention also encompansses methods for use of NKG2D-DAP10-CD3 zeta polypeptides, vectors and cells in methods for treating cancer and other proliferative disorders, as well as infectious diseases.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: January 21, 2020
    Assignees: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Dario Campana, Yu-Hsiang Chang
  • Patent number: 10541689
    Abstract: A clock generation circuit arranged in a first system is disclosed. The clock generation circuit includes: a first dual-mode PLL, arranged for generating a first output clock in an integer-N mode or a fractional-N mode selectively, the first output clock being generated based on a first reference clock; and a second dual-mode PLL, arranged for generating a second output clock in an integer-N mode or a fractional-N mode selectively, the second output clock being generated based on the first output clock or a second reference clock selectively. Associated circuitries are also disclosed.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: January 21, 2020
    Assignee: M31 TECHNOLOGY CORPORATION
    Inventors: Yu Hsiang Chang, Ching-Hsiang Chang
  • Publication number: 20200014389
    Abstract: A clock generation circuit arranged in a first system is disclosed. The clock generation circuit includes: a first dual-mode PLL, arranged for generating a first output clock in an integer-N mode or a fractional-N mode selectively, the first output clock being generated based on a first reference clock; and a second dual-mode PLL, arranged for generating a second output clock in an integer-N mode or a fractional-N mode selectively, the second output clock being generated based on the first output clock or a second reference clock selectively. Associated circuitries are also disclosed.
    Type: Application
    Filed: July 6, 2018
    Publication date: January 9, 2020
    Inventors: YU HSIANG CHANG, CHING-HSIANG CHANG
  • Publication number: 20180288725
    Abstract: A method for constructing a database of Wi-Fi beacon locations is provided. The method includes: storing raw observation data for Wi-Fi beacons in the database of Wi-Fi beacon locations; (b) generating observation data records for the Wi-Fi beacons according to the raw observation data, and computing a rough location estimate for each Wi-Fi beacon according to the observation data records; (c) finding outliers of each Wi-Fi beacon from the rough location estimate and the observation data records; (d) excluding the outliers from the observation data records, and computing final location estimates for the Wi-Fi beacons according to the observation data records which do not include the outliers; (e) computing inferred-location estimates for the Wi-Fi beacons which do not have a location fix according to the final location estimates; and (f) storing the inferred-location estimates in the beacon location database.
    Type: Application
    Filed: March 28, 2017
    Publication date: October 4, 2018
    Inventors: Yi-Lin Chen, Yu-Hsiang Chang
  • Publication number: 20180135013
    Abstract: The invention provides a chimeric receptor comprising NKG2D, DAP10 and CD3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of NK cells. The invention also encompasses methods for use of NKG2D-DAP10-CD3 zeta polypeptides, vectors and cells in methods for treating cancer and other proliferative disorders, as well as infectious diseases.
    Type: Application
    Filed: December 28, 2017
    Publication date: May 17, 2018
    Applicants: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Dario Campana, Yu-Hsiang Chang
  • Publication number: 20180135014
    Abstract: The invention provides a chimeric receptor comprising NKG2D, DAP10 and CD3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of NK cells. The invention also encompasses methods for use of NKG2D-DAP10-CD3 zeta polypeptides, vectors and cells in methods for treating cancer and other proliferative disorders, as well as infectious diseases.
    Type: Application
    Filed: December 28, 2017
    Publication date: May 17, 2018
    Applicants: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Dario Campana, Yu-Hsiang Chang
  • Publication number: 20180135016
    Abstract: The invention provides a chimeric receptor comprising NKG2D, DAP10 and CD3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of NK cells. The invention also encompasses methods for use of NKG2D-DAP10-CD3 zeta polypeptides, vectors and cells in methods for treating cancer and other proliferative disorders, as well as infectious diseases.
    Type: Application
    Filed: December 28, 2017
    Publication date: May 17, 2018
    Applicants: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Dario Campana, Yu-Hsiang Chang
  • Publication number: 20180135015
    Abstract: The invention provides a chimeric receptor comprising NKG2D, DAP10 and CD3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of NK cells. The invention also encompasses methods for use of NKG2D-DAP10-CD3 zeta polypeptides, vectors and cells in methods for treating cancer and other proliferative disorders, as well as infectious diseases.
    Type: Application
    Filed: December 28, 2017
    Publication date: May 17, 2018
    Applicants: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC, NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Dario Campana, Yu-Hsiang Chang
  • Publication number: 20170107491
    Abstract: The invention provides a chimeric receptor comprising NKG2D, DAP10 and CD3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of NK cells. The invention also encompansses methods for use of NKG2D-DAP10-CD3 zeta polypeptides, vectors and cells in methods for treating cancer and other proliferative disorders, as well as infectious diseases.
    Type: Application
    Filed: October 28, 2016
    Publication date: April 20, 2017
    Applicants: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Dario Campana, Yu-Hsiang Chang
  • Patent number: 9511092
    Abstract: The invention provides a chimeric receptor comprising NKG2D, DAP10 and CD3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of NK cells. The invention also encompasses methods for the use of NKG2D-DAP10-CD3 zeta polypeptides, vectors and cells in methods for treating cancer and other proliferative disorders, as well as infectious diseases.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: December 6, 2016
    Assignees: St. Jude Children's Research Hospital, Inc., National University of Singapore
    Inventors: Dario Campana, Yu-Hsiang Chang
  • Patent number: 9478851
    Abstract: An antenna structure comprising a substrate and an antenna is provided. The substrate comprises an upper surface and an under surface. The antenna comprises a first metal pattern and a second metal pattern. The first metal pattern is disposed on the upper surface. The first metal pattern comprises a feeding portion and a transmission line connected to the feeding portion. The second metal pattern is disposed on the under surface, and comprises a first parasitic grounding arm, a second parasitic grounding arm, a connecting arm, a grounding plane and a grounding strip. The connecting arm has a parasitic slot, and connects the first parasitic grounding arm and the second parasitic grounding arm. The grounding strip connects the connecting arm and the grounding plane.
    Type: Grant
    Filed: December 24, 2013
    Date of Patent: October 25, 2016
    Assignee: ARCADYAN TECHNOLOGY CORPORATION
    Inventors: Shin-Lung Kuo, Yi-Cheng Lin, Keng-Chih Lin, Yu-Hsiang Chang, Shih-Chieh Cheng
  • Patent number: 9391239
    Abstract: A light emitting diode includes a semiconductor stacked structure, a substrate, a first electrode, a second electrode and a third electrode. The semiconductor stacked structure includes a first semiconductor layer, a second semiconductor layer and a light emitting layer. The first semiconductor layer has a first surface and a second surface opposite to each other and has a first region and a second region. The second semiconductor layer is disposed on the second surface. The light emitting layer is disposed between the first semiconductor layer and the second semiconductor layer. The substrate has a first conductive layer and a second conductive layer thereon. The first electrode is disposed between the second semiconductor layer and the first conductive layer. The second electrode is disposed on the first surface. The third electrode is disposed between the second region and the second conductive layer, and electrically connected to the second electrode.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: July 12, 2016
    Assignee: Industrial Technology Research Institute
    Inventors: Yao-Jun Tsai, Chen-Peng Hsu, Shih-Yi Wen, Chi-Chin Yang, Yu-Hsiang Chang, Re-Ching Lin, Hung-Lieh Hu
  • Publication number: 20160000828
    Abstract: The invention provides a chimeric receptor comprising NKG2D, DAP10 and CD3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of NK cells. The invention also encompasses methods for the use of NKG2D-DAP10-CD3 zeta polypeptides, vectors and cells in methods for treating cancer and other proliferative disorders, as well as infectious diseases.
    Type: Application
    Filed: January 28, 2014
    Publication date: January 7, 2016
    Applicants: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Dario CAMPANA, Yu-Hsiang CHANG
  • Patent number: 9191128
    Abstract: A spread spectrum clock generator for generating a spread spectrum clock signal is provided. The spread spectrum clock generator includes a phase-locked loop system and a random walk modulator. The random walk modulator generates a modulating signal according to a random walk model. Then, the phase-locked loop system generates a clock signal with spread spectrum in response to the modulating signal. A method for generating the spread spectrum clock signal using the spread spectrum clock generator is also provided.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: November 17, 2015
    Assignee: NATIONAL APPLIED RESEARCH LABORATORIES
    Inventors: Yu-Shao Shiao, Yu-Hsiang Chang, Guo-Wei Huang
  • Publication number: 20150179880
    Abstract: A nitride light emitting diode structure including a first type doped semiconductor layer, a second type doped semiconductor layer, a light emitting layer, a first metal pad, a second metal pad and a magnetic film is disclosed. The magnetic film disposed between the first metal pad and the first type doped semiconductor layer includes a zinc oxide (ZnO) layer doped with cobalt (Co). The content of Co in the ZnO layer ranges from 5% to 25% by molar ratio.
    Type: Application
    Filed: December 24, 2013
    Publication date: June 25, 2015
    Applicant: Industrial Technology Research Institute
    Inventors: Yen-Hsiang Fang, Rong Xuan, Chia-Lung Tsai, Yu-Hsiang Chang
  • Publication number: 20150171274
    Abstract: The present disclosure provides a LED structure which comprises an epitaxial layer, a current dispatching layer, a first electrode layer, and a second electrode layer. The epitaxial layer comprises sequentially disposed a high resistance buffer layer, a first GaN layer, an active layer, and a second GaN layer. A plurality of recesses are formed on a first surface of the epitaxial layer, each of the recesses has an opening on the first surface, penetrates the high resistance buffer layer, and contacts the first GaN layer. The current dispatching layer is disposed on the first surface of the epitaxial layer, and is disposed into the recesses for contacting the first GaN layer. The first electrode layer is disposed on the current dispatching layer, and the second electrode layer is disposed on a second surface of the epitaxial layer.
    Type: Application
    Filed: December 17, 2013
    Publication date: June 18, 2015
    Applicant: Industrial Technology Research Institute
    Inventors: Yih-Der GUO, Yu-Hsiang CHANG, Kun-Fong LIN
  • Publication number: 20150171918
    Abstract: A spread spectrum clock generator for generating a spread spectrum clock signal is provided. The spread spectrum clock generator includes a phase-locked loop system and a random walk modulator. The random walk modulator generates a modulating signal according to a random walk model. Then, the phase-locked loop system generates a clock signal with spread spectrum in response to the modulating signal. A method for generating the spread spectrum clock signal using the spread spectrum clock generator is also provided.
    Type: Application
    Filed: December 17, 2013
    Publication date: June 18, 2015
    Applicant: NATIONAL APPLIED RESEARCH LABORATORIES
    Inventors: Yu-Shao Shiao, Yu-Hsiang Chang, Guo-Wei Huang
  • Publication number: 20140354504
    Abstract: An antenna structure comprising a substrate and an antenna is provided. The substrate comprises an upper surface and an under surface. The antenna comprises a first metal pattern and a second metal pattern. The first metal pattern is disposed on the upper surface. The first metal pattern comprises a feeding portion and a transmission line connected to the feeding portion. The second metal pattern is disposed on the under surface, and comprises a first parasitic grounding arm, a second parasitic grounding arm, a connecting arm, a grounding plane and a grounding strip. The connecting arm has a parasitic slot, and connects the first parasitic grounding arm and the second parasitic grounding arm. The grounding strip connects the connecting arm and the grounding plane.
    Type: Application
    Filed: December 24, 2013
    Publication date: December 4, 2014
    Applicant: ARCADYAN TECHNOLOGY CORPORATION
    Inventors: Shin-Lung KUO, Yi-Cheng LIN, Keng-Chih LIN, Yu-Hsiang CHANG, Shih-Chieh CHENG
  • Publication number: 20140231851
    Abstract: A light emitting diode includes a semiconductor stacked structure, a substrate, a first electrode, a second electrode and a third electrode. The semiconductor stacked structure includes a first semiconductor layer, a second semiconductor layer and a light emitting layer. The first semiconductor layer has a first surface and a second surface opposite to each other and has a first region and a second region. The second semiconductor layer is disposed on the second surface. The light emitting layer is disposed between the first semiconductor layer and the second semiconductor layer. The substrate has a first conductive layer and a second conductive layer thereon. The first electrode is disposed between the second semiconductor layer and the first conductive layer. The second electrode is disposed on the first surface. The third electrode is disposed between the second region and the second conductive layer, and electrically connected to the second electrode.
    Type: Application
    Filed: January 29, 2014
    Publication date: August 21, 2014
    Applicant: Industrial Technology Research Institute
    Inventors: Yao-Jun Tsai, Chen-Peng Hsu, Shih-Yi Wen, Chi-Chin Yang, Yu-Hsiang Chang, Re-Ching Lin, Hung-Lieh Hu
  • Publication number: 20140225375
    Abstract: A power supply device for a door handle is provided. A rotation shaft of the door handle is provided with a drive gear, a first speed-change gear, a second speed-change gear, and a generator. Two end of a rotation shaft of the generator are respectively provided with a gravity wheel and a freewheel. The freewheel has one-way teeth, a link plate with link teeth and a third speed-change gear. The third speed-change gear meshes with the second speed-change gear. When the door handle is turned to an angle, the drive gear, the first and second speed-change gears, the third speed-change gear and the freewheel are driven to turn so that the rotation shaft of the generator is turned to generate power for an electric lock (such as a fingerprint lock, a coded lock, a chip induction lock).
    Type: Application
    Filed: February 14, 2013
    Publication date: August 14, 2014
    Inventor: Yu Hsiang Chang