Abstract: The patent discloses self-emulsifying formulations of bisphosphonates or bisphosphonic acids in the prevention and treatment of conditions involving calcium or phosphate metabolism. The dosage forms are either capsules, or tablets, or other controlled release drug delivery systems, or devices that contain self-emulsifying formulation of such bisphosphonates or bisphosphonic acids.

Abstract: A resonator including a piezoelectric plate and an interdigital electrode is provided. A ratio between a thickness of the plate and a pitch of the interdigital electrode may be from about 0.5 to about 1.5. A radiation detector including a resonator and an absorber layer capable of absorbing at least one of infrared and terahertz radiation is provided. A resonator including a piezoelectric plate and a two-dimensional electrically conductive material is provided.

Abstract: This invention discloses a bioadhesive boric acid formulation and its preparation method. Specifically, preferred vaginal bioadhesive boric acid formulation mainly comprises chitosan, carbopol 974 , polycarbophil, boric acid, and purified water as a gel. The main performance characteristic of this vaginal boric acid preparation is the ability of the formulation to retain and release boric acid in the vagina by using a combination of carbopol 974 and polycarbophil as preferred bioadhesive polymers. It was proved experimentally that boric acid as the antibacterial component of this gel can be maintained at a relatively high concentration (>10 mg/mL) in vagina for an extended period of time (>2 hours) with the use of a combination of polyacrylic acid polymers, i.e. carbopol 974 and polycarbophil.

Abstract: A resonator includes a piezoelectric plate and interdigitated electrode(s). The interdigitated electrode includes a plurality of conductive strips disposed over a top surface of the piezoelectric plate. A two-dimensional mode of mechanical vibration is excited in a cross sectional plane of the piezoelectric plate in response to an alternating voltage applied through the interdigitated electrode. The two-dimensional mode of mechanical vibration is a cross-sectional Lamé mode resonance (CLMR) or a degenerate cross-sectional Lamé mode resonance (dCLMR).

Abstract: A resonator includes a piezoelectric plate and interdigitated electrode(s). The interdigitated electrode includes a plurality of conductive strips disposed over a top surface of the piezoelectric plate. A two-dimensional mode of mechanical vibration is excited in a cross sectional plane of the piezoelectric plate in response to an alternating voltage applied through the interdigitated electrode. The two-dimensional mode of mechanical vibration is a cross-sectional Lamé mode resonance (CLMR) or a degenerate cross-sectional Lamé mode resonance (dCLMR).

Abstract: Microfluidic oscillator circuits and pumps for microfluidic devices are provided. The microfluidic pump may include a plurality of fluid valves and a microfluidic oscillator circuit having an oscillation frequency. The fluid valves may be configured to move fluids. Each fluid valve may be connected to a node of the microfluidic oscillator circuit. The pumps may be driven by the oscillator circuits such that fluid movement is accomplished entirely by circuits on a microfluidic chip, without the need for off-chip controls.

Abstract: An electrical connector includes an insulative housing, a plurality of contacts retained in the insulative housing, a fastener and a first sealing ring. The insulative housing has a rear section extending backwardly. The rear section has a rear space and a first peripheral wall around the rear space. Each contact has a connecting leg extending into the rear space. The fastener has a mating section to engage with the rear section and a board receiving chamber extending therethrough along a front to back direction. The fastener has a fixed position on the insulative housing, and as moving the fastener to the fixed position, the connecting legs are pressed into the board receiving chamber for electrically connecting with the flexible printed circuit board, and the first sealing ring is sealed around the junction of the contacts and the flexible printed circuit board.

Abstract: The present invention provides processes for the preparation of ataluren. Intermediates for preparing ataluren are also provided.

Abstract: A resonator including a piezoelectric plate and an interdigital electrode is provided. A ratio between a thickness of the plate and a pitch of the interdigital electrode may be from about 0.5 to about 1.5. A radiation detector including a resonator and an absorber layer capable of absorbing at least one of infrared and terahertz radiation is provided. A resonator including a piezoelectric plate and a two-dimensional electrically conductive material is provided.

Abstract: An electrical connector includes an insulative housing, a plurality of contacts retained in the insulative housing, a fastener and a first sealing ring. The insulative housing has a rear section extending backwardly. The rear section has a rear space and a first peripheral wall around the rear space. Each contact has a connecting leg extending into the rear space. The fastener has a mating section to engage with the rear section and a board receiving chamber extending therethrough along a front to back direction. The fastener has a fixed position on the insulative housing, and as moving the fastener to the fixed position, the connecting legs are pressed into the board receiving chamber for electrically connecting with the flexible printed circuit board, and the first sealing ring is sealed around the junction of the contacts and the flexible printed circuit board.

Abstract: Pneumatic devices for implementing finite state machines are provided. In some implementations, the pneumatic device comprises a state register component configured to hold one of a set of possible states. The pneumatic device also comprises a next-state logic block component configured to determine a next state for the state register component based at least in part on a current state of the state register component. A pneumatic programmable logic array (PLA) implementing a next state logic block of a finite state machine is also provided. The pneumatic PLA comprises an elastomeric membrane containing a pattern of holes and disposed between two channel layers of a pneumatic device. The PLA receives one or more input values representing a current state of a state register and one or more input values representing a user input and calculates one or more output values representing a next state for the state register.

Abstract: A mechanism is provided for searching a virtual resource in a large scale computing system environment. The virtual resource is deployed on at least one server. Each server is coupled to a sensor and communicates with the sensor. The sensors communicate with each other and consist of a communication network. Each sensor stores an identifier of a virtual resource deployed in a server connected with the sensor and the location information of the sensor itself. The mechanism receives a searching request for a virtual resource by the at least one sensor, the searching request containing an identifier of the virtual resource being searched; forwards the searching request in the communication network of the sensors; and returns a location information of a sensor storing the identifier of the virtual resource by the sensor itself.

Abstract: The present invention discloses a machining technology of a low-temperature high-strength-ductility high manganese steel, high manganese steel plate, and high manganese steel tube, and a high manganese steel comprises the following components in percentage by weight: Mn 30%-36%, C 0.02%-0.06%, S?0.01%, P?0.008% and the balance being Fe. Smelted steel ingots are subject to solution treatment and are rolled and homogenized to obtain a high manganese steel plate or are drawn to form a high manganese steel tube. The hot-rolled or cold-rolled steel plate after being hot-rolled has tremendous application value in the fields of low-temperature applications, such as the steel plate used for a low temperature pressure container.

Abstract: Aspects of the technology relate to a cover (e.g., for a handheld electronic device). The cover may include a cover body configured for securement to a handheld electronic device and comprising an accessory attachment area, wherein the accessory attachment area includes a plurality of receivers, and wherein the accessory attachment area is configured for coupling with an accessory in at least one of a plurality of orientations. In some aspects, each receiver further includes a space recessed into the cover body that is bounded, at least partially, by a recess wall, wherein each receiver includes an engagement surface configured for abutting engagement with a projection associated with an accessory when the projection is disposed in a secured configuration within a respective space. An electrical device cover and various attachment devices are also provided.

Abstract: An electrical connector includes an insulative housing, a plurality of contacts retained in the insulative housing and a fastener. The insulative housing has a rear surface. Each contact has a connecting leg extending beyond the rear surface. The connecting legs are arranged in at least a row, and each connecting leg has a connecting portion and a resisting portion. The fastener has at least a contact receiving chamber, a flexible circuit board receiving chamber communicating with the contact receiving chamber and a press section. The contact receiving chamber is arranged between from the flexible circuit board receiving chamber and the press section. Wherein the fastener has a fixed position on the insulative housing, and as moving the fastener to the fixed position, the press section presses the resisting portion to drive the connecting portion projecting into the flexible circuit board receiving chamber.

Abstract: A resonator includes a piezoelectric plate and interdigitated electrode(s). The interdigitated electrode includes a plurality of conductive strips disposed over a top surface of the piezoelectric plate. A two-dimensional mode of mechanical vibration is excited in a cross sectional plane of the piezoelectric plate in response to an alternating voltage applied through the interdigitated electrode. The two-dimensional mode of mechanical vibration is a cross-sectional Lamé mode resonance (CLMR) or a degenerate cross-sectional Lamé mode resonance (dCLMR).

Abstract: A resonator including a piezoelectric plate and an interdigital electrode is provided. A ratio between a thickness of the plate and a pitch of the interdigital electrode may be from about 0.5 to about 1.5. A radiation detector including a resonator and an absorber layer capable of absorbing at least one of infrared and terahertz radiation is provided. A resonator including a piezoelectric plate and a two-dimensional electrically conductive material is provided.

Abstract: A sol-gel composition for acrylic polymers-based substrate including at least a silane hydrolysate and at least an adhesion promoter including a dendritic polymer having hydroxyl and alkoxysilane groups at terminal ends thereof. An optical article coated with said sol-gel composition.

Abstract: Aspects of the technology relate to a cover (e.g., for a handheld electronic device). The cover may include a cover body configured for securement to a handheld electronic device and comprising an accessory attachment area, wherein the accessory attachment area includes a plurality of receivers, and wherein the accessory attachment area is configured for coupling with an accessory in at least one of a plurality of orientations. In some aspects, each receiver further includes a space recessed into the cover body that is bounded, at least partially, by a recess wall, wherein each receiver includes an engagement surface configured for abutting engagement with a projection associated with an accessory when the projection is disposed in a secured configuration within a respective space. An electrical device cover and various attachment devices are also provided.