Abstract: The present application belongs to the field of biotechnology, and particularly relates to preparation and use of soluble Tim-3 recombinant protein and a mutant protein thereof. The soluble Tim-3 recombinant protein is used to prepare a drug with the function of regulating monocytes or a drug with the function of enhancing tumor immune response, and the amino acid sequence of the soluble Tim-3 recombinant protein is as shown in SEQ ID NO: 1. In addition, the present application further provides the mutant proteins of the sTim-3 recombinant protein and preparation and use of the mutant protein. The mutant recombinant protein is obtained by screening through a directed evolutionary technology, with the function of regulating monocytes or the function of enhancing tumor immune response, and combines with a host codon optimization method to improve the expression efficiency.

Abstract: An example intent-recognition system comprises a processor and memory storing instructions. The instructions cause the processor to receive speech input comprising spoken words. The instructions cause the processor to generate text results based on the speech input and generate acoustic feature annotations based on the speech input. The instructions also cause the processor to apply an intent model to the text result and the acoustic feature annotations to recognize an intent based on the speech input. An example system for adapting an emotional text-to-speech model comprises a processor and memory. The memory stores instructions that cause the processor to receive training examples comprising speech input and receive labelling data comprising emotion information associated with the speech input. The instructions also cause the processor to extract audio signal vectors from the training examples and generate an emotion-adapted voice font model based on the audio signal vectors and the labelling data.

Abstract: An optical assembly is configured to receive visible scene light at a backside of the optical assembly and to direct the visible scene light on an optical path toward the eyeward side. The optical assembly also includes a dimming layer disposed on the optical path, where the dimming layer includes a photochromic material that is configured to darken in response to exposure to a range of light wavelengths. An activation layer, included in the optical assembly, is also disposed on the optical path and includes an in-field dimmer. The in-field dimmer is configured to selectively emit an activation light within the range of light wavelengths to activate a darkening of a region of the dimming layer to dim the visible scene light within the region.

Abstract: This disclosure provides new methods to characterize and relate residual stress and orientation imparted to the injection molded polymeric preform with orientation and residual stress in the resulting blow molded bottle. The method developed allows one to define and map the coupled thermal stress histories of both processes to define applicable preferred mutual processing windows for both preform and bottle molding processes. Stretch blow-molding parameters are developed using the disclosed method.

Abstract: A transcription of audio speech included in electronic content associated with a meeting is created by an ASR model trained on speech-to-text data. The transcription is post-processed by modifying text included in the transcription, for example, by modifying punctuation, grammar, or formatting introduced by the ASR model and by changing or omitting one or more words that were included in both the audio speech and the transcription. After the transcription is post-processed, output based on the post-processed transcription is generated in the form of a meeting summary and/or template.

Abstract: A method for extracting significant texture features of a B-ultrasonic image and application thereof discloses a channel attention mechanism network, i.e. a context activation residual network, which is designed to effectively model the B-ultrasonic liver fibrosis texture information, and which uses the global context information to strengthen important texture features and suppress useless texture features, such that the deep residual network can capture more significant texture information in the B-ultrasonic images. The process can be mainly divided into two phases: training and testing. During the training phase, the context activation residual network may he trained by using the B-ultrasonic image blocks as input and the pathological results of liver biopsy as labels. During the testing phase, the B-ultrasonic image blocks may be input into the trained non-invasive liver fibrosis diagnosis model to obtain the liver fibrosis staging result for each ultrasonic image.

Abstract: A flexible micro light emitting diode display panel and a micro light emitting diode display device are provided. The flexible micro light emitting diode display panel includes: a supporting board comprising a top surface, a bottom surface, at least one side surface, and at least one top circular chamfer. The at least one side surface is connected to the top surface and the bottom surface, and the at least one circular chamfer is connected to the top surface and the side surface. A flexible micro light emitting diode substrate includes a display region and at least one frame portion, the display region is formed on the top surface, and the display region comprises micro light emitting diodes. The at least one frame portion is in contact with the at least one top circular chamfer and the side surface, and a printed circuit board electrically connected to the frame portion.

Abstract: A pupil replication waveguide for a projector display includes a slab of transparent material for propagating display light in the slab via total internal reflection. A diffraction grating is supported by the slab. The diffraction grating includes a plurality of tapered slanted fringes in a substrate for out-coupling the display light from the slab by diffraction into a blazed diffraction order. A greater portion of the display light is out-coupled into the blazed diffraction order, and a smaller portion of the display light is out-coupled into a non-blazed diffraction order. The tapered fringes result in the duty cycle of the diffraction grating varying along the thickness direction of the diffraction grating, to facilitate suppressing the portion of the display light out-coupled into the non-blazed diffraction order.

Abstract: An optical assembly is configured to receive visible scene light at a backside of the optical assembly and to direct the visible scene light on an optical path toward the eyeward side. The optical assembly also includes a dimming layer disposed on the optical path, where the dimming layer includes a photochromic material that is configured to darken in response to exposure to a range of light wavelengths. An activation layer, included in the optical assembly, is also disposed on the optical path and includes an in-field dimmer. The in-field dimmer is configured to selectively emit an activation light within the range of light wavelengths to activate a darkening of a region of the dimming layer to dim the visible scene light within the region.

Abstract: A device includes an optical assembly and a digital projector. The optical assembly is configured to receive visible scene light at a backside of the optical assembly and to direct the visible scene light on an optical path toward an eyeward side. The optical assembly includes a dimming layer disposed on the optical path. The dimming layer includes a photochromic material that is configured to darken in response to exposure to a range of light wavelengths. The digital projector is disposed on the eyeward side of the optical assembly and is configured to selectively emit an activation light within the range of light wavelengths to activate a darkening of a region of the dimming layer to dim the visible scene light within the region.

Abstract: This disclosure provides economical and effective methods and apparatus for repairing scratches and scuffs on refillable bottle surfaces that minimally contaminates the bottle during the refurbishing process. In one aspect, the method comprises the steps of: a) adding at least one fluid into the polymeric packaging material such as a bottle to form at least a partially filled packaging material; and b) applying at least one heat source to an exterior surface of the at least partially filled packaging material to form a repaired polymeric packaging material. Apparatus and recycling systems that incorporate this method are also disclosed.

Abstract: Embodiments of the present disclosure relate generally to determining node embedding using multi-view graphs for analyzing electronic content.

Abstract: Preforms and methods of processing 2,5-furandicarboxylic acid (FDCA) polymers, such as poly(ethylene-2,5-furandicaboxylate (PEF), to produce preforms and articles, such as containers. The present invention also includes preforms with superior processing characteristics and containers, such as PEF beverage bottles, with superior performance properties.

Abstract: An isotropic imaging filter is provided that includes a photonic crystal slab, where the photonic crystal slab includes a square lattice of air through holes, a dielectric constant, a thickness (d), a through hole radius (r), and a lattice constant (a), where the square lattice of air holes are separated according to a value of the lattice constant, where the thickness is configured according to d=M(a), where the through hole radii is configured according to r=N(a), where the thickness and the hole radii are configured to generate isotropic bands of guided resonances of an incident image.

Abstract: Provided is a method for preparing a diol. In the method, a saccharide and hydrogen as raw materials are contacted with a catalyst in water to prepare the diol. The employed catalyst is a composite catalyst comprised of a main catalyst and a cocatalyst, wherein the main catalyst is a water-insoluble acid-resistant alloy; and the cocatalyst is a soluble tungstate and/or soluble tungsten compound. The method uses an acid-resistant, inexpensive and stable alloy needless of a support as a main catalyst, and can guarantee a high yield of the diol in the case where the production cost is relatively low.

Abstract: A pupil replication waveguide for a projector display includes a slab of transparent material for propagating display light in the slab via total internal reflection. A diffraction grating is supported by the slab. The diffraction grating includes a plurality of tapered slanted fringes in a substrate for out-coupling the display light from the slab by diffraction into a blazed diffraction order. A greater portion of the display light is out-coupled into the blazed diffraction order, and a smaller portion of the display light is out-coupled into a non-blazed diffraction order. The tapered fringes result in the duty cycle of the diffraction grating varying along the thickness direction of the diffraction grating, to facilitate suppressing the portion of the display light out-coupled into the non-blazed diffraction order.

Abstract: Steviol glycoside blends comprising rebaudioside A, rebaudioside M, rebaudioside D and rebaudioside B that have aqueous solubility at relevant beverage concentrate concentrations are provided herein. Blends comprising steviol glycoside blends of the present invention and compositions comprising glucosylated steviol glycosides are also provided. Beverage syrups and beverages made from these blends are also provided.

Abstract: Provided are an apparatus and method for a hybrid multiple access wireless communication system. The apparatus comprises: a parameter acquisition unit configured to acquire a relevant parameter of a hybrid multiple access wireless communication system; and a sub-carrier allocation unit configured to use the relevant parameter to allocate sub-carriers to each user equipment with the purpose of optimizing overall communication quality of the hybrid multiple access wireless communication system.

Abstract: An example intent-recognition system comprises a processor and memory storing instructions. The instructions cause the processor to receive speech input comprising spoken words. The instructions cause the processor to generate text results based on the speech input and generate acoustic feature annotations based on the speech input. The instructions also cause the processor to apply an intent model to the text result and the acoustic feature annotations to recognize an intent based on the speech input. An example system for adapting an emotional text-to-speech model comprises a processor and memory. The memory stores instructions that cause the processor to receive training examples comprising speech input and receive labelling data comprising emotion information associated with the speech input. The instructions also cause the processor to extract audio signal vectors from the training examples and generate an emotion-adapted voice font model based on the audio signal vectors and the labelling data.