Abstract: A method is provided that includes: obtaining a first state information of the remote driving system, where the remote driving system is configured to perform remote control on a vehicle communicatively connected with the remote driving system; determining whether an abnormality occurs in the remote driving system based on the first state information; determining abnormality information of the remote driving system in response to the occurrence of the abnormality in the remote driving system; and adjusting a state of the remote control based on the abnormality information.

Abstract: An object processing method includes: displaying a first operation interface in response to triggering a first operation control of a first stage of a target object, the first operation interface including at least one first operation item; displaying a content input interface in response to completing an operation for the at least one first operation item, the content input interface including at least one input item; in response to completion of content input for the at least one input item, determining a second target value and generating a second operation control corresponding to a second stage of the target object; displaying a second operation interface in response to triggering the second operation control, the second operation interface including at least one second operation item; and updating the state of the target object to a completed state in response to completing an operation for the second operation item.

Abstract: Provided are an auxiliary alloy casting piece, a high-remanence and high-coercive force NdFeB permanent magnet, and preparation methods thereof. The method for preparing the auxiliary alloy casting piece includes the following steps: providing an auxiliary alloy material including, by mass percentage, 40% to 45% of Pr, 1% to 2% of Co, 0.5% to 1% of Ga, 0.6% to 0.8% of B, 0.1% to 0.2% of V, 0.3% to 0.7% of Ti, and a balance of Fe; smelting the auxiliary alloy material to obtain a smelted material; and subjecting the smelted material to a quick-setting casting to obtain the auxiliary alloy casting piece; where the quick-setting casting includes a refining and a casting in sequence.

Abstract: The present invention belongs to the field of tumor treatment and molecular immunology, and specifically relates to a therapeutic combination and use thereof. Specifically, the therapeutic combination comprises an anti-CTLA4-anti-PD-1 bispecific antibody and an anti-PD-1-anti-VEGFA bispecific antibody. The therapeutic combination of the present invention can effectively treat or prevent a tumor and has good application prospects.

Abstract: In one embodiment, a method includes determining, by a first network component, a sender shaper drop value based on the following: a maximum sequence number; a minimum sequence number; and a sender sequence counter number associated with the first network component. The method also includes determining, by the first network component, a wide area network (WAN) link drop value based on the sender sequence counter number associated with the first network component and a receiver sequence counter number associated with a second network component. The method further includes determining, by the first network component, whether to adjust a sender shaper rate based on the sender shaper drop value and the WAN link drop value.

Abstract: A device and a method for experimental exploitation of natural gas hydrates in full-sized production wells are provided. The device includes a full-diameter well, and the full-diameter well includes a heating circulation tube, a temperature sensor tube, an upper sealing unit and a lower sealing unit. Perforations are provided along a body of the full-diameter well. A reactor includes an upper cover, a lower cover, and a reactor body. The method is conducted by using the device and the reactor. The device and method allow simulation of sand-control wellbores in actual exploitation of natural gas hydrates, and realize horizontal and vertical sand-control experiments.

Abstract: A reshaping method for metal product includes acquiring position data information of a workpiece; converting the position data information into coordinate information, and fitting the coordinate information to obtain a surface contour curve of the workpiece; comparing the surface contour curve with a standard contour curve to generate a comparison result; obtaining reshaping information of the workpiece based on the comparison result; and controlling the reshaping system to reshape the workpiece. The disclosure acquires position data information of the workpiece by measuring, converts the position data information into coordinate information, fits the coordinate information to obtain the surface contour curve of the workpiece, compares the surface contour curve with the standard contour curve to obtain deformation situation, and reshapes the workpiece according to the reshaping information based on the deformation situation, which improves efficiency of workpiece reshaping and reducing labor costs.

Abstract: A high-performance multilayer films for packaging and the structure of the multilayer film is as follows: PO2/POY/PO1/POX/PO3 and PO2/POY/PO1/TIE2/PO3. The multilayer film is obtained by multilayer coextrusion and biaxial stretching. The total thickness of the multilayer film is 8 to 100 micrometers; the absolute values of the differences of the solubility parameters between the PO1 layer and the PO2 layer and between the PO2 layer and PO3 layer is greater than 0.5 (J·cm?3)1/2, and the absolute value of the difference of the cohesive energy density is greater than 5 J/cm3.

Abstract: A refrigerator includes a receiving chamber and a drawer movably received in the receiving chamber. The drawer is at a first location when it is closed. The refrigerator further includes a first sensor that is fixed to the drawer or a wall of the receiving chamber. The first sensor is configured to detect when the drawer reaches a second location. The first and second locations are spaced apart by a spacing distance.

Abstract: The invention relates to the field of medicinal chemistry, and discloses a class of biphenyl derivatives with PD-1/PD-L1 inhibitory activity, and a preparation method and use thereof. The invention further discloses a composition containing the biphenyl derivatives with PD-1/PD-L1 inhibitory activity or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier, and applications of the composition in preparation of PD-1/PD-L1 inhibitors. The compounds of the invention are useful in the therapy used to treat tumors.

Abstract: An anti-CD47 monoclonal antibody and the use thereof in combination with a monoclonal antibody, a bispecific antibody and/or a tumor therapeutic agent, wherein the anti-CD47 monoclonal antibody is secreted by a hybridoma cell line with a deposit number of CCTCC NO: C2018135.

Abstract: The present invention discloses a monoclonal antibody against nerve growth factor, and an encoding gene and use thereof. The monoclonal antibody comprises heavy chains comprising a heavy chain constant region and a heavy chain variable region, and light chains comprising a light chain constant region and a light chain variable region. The heavy chain variable region comprises three complementarity determining regions HCDR1, HCDR2 and HCDR3, and the light chain variable region comprises three complementarity determining regions LCDR1, LCDR2 and LCDR3. The monoclonal antibody can specifically bind to nerve growth factor, and can be used to detect the presence and/or level of nerve growth factor, as well as to prepare a drug for inhibiting the nerve growth factor-dependent proliferation of TF-1 cells, and for treating or preventing at least one of neuropathic pain, chronic pain, and inflammatory pain, thus having good application prospects and marketing value.

Abstract: This invention relates to a thin-film transistor including, a dielectric layer having a first side and an opposed second side; a source electrode, a drain electrode separated from the source electrode, and a semiconductor component disposed between and in contact with the source electrode and the drain electrode, the source electrode, the drain electrode and the semiconductor component being disposed adjacent the first side of the dielectric layer; and a gate electrode disposed adjacent the second side of the dielectric layer opposite the semiconductor component; wherein the semiconductor component comprises one or more n-type organic semiconductor materials based on arene-bis(dicarboximide)s, and wherein the thin-film transistor has a channel length, measured as the shortest path from the source electrode to the drain electrode, of no more than 20 ?m.

Abstract: An anti-CD73 antibody and the use thereof. The heavy chain variable region of the antibody comprises HCDR1-HCDR3 having amino acid sequences as shown in SEQ ID NOs: 15-17; and the light chain variable region of the antibody comprises LCDR1-LCDR3 having amino acid sequences as shown in SEQ ID NOs: 18-20.

Abstract: An anti-CTLA4 (cytotoxic T lymphocyte associated antigen 4) and anti-PD-1 (programmed cell death 1) bifunctional antibody. a pharmaceutical composition thereof and use thereof. Particularly, the anti-CLTA4 and anti-PD-1 bifunctional antibody comprises a first protein functional domain that targets PD-1 and a second protein functional domain that targets CTLA-4. The bifunctional antibody can bind to CTLA-4 and PD-1 specifically, relieve immunosuppression of CTLA4 and PD-1 on an organism specifically, activate T lymphocytes, and thus has good application prospects.

Abstract: An ant-TIGIT antibody, and a pharmaceutical composition and the use thereof. The present invention relates to an anti-TIGIT antibody or an antigen-binding fragment thereof, wherein a heavy chain variable region of the antibody comprises HCDR1-HCDR3 having amino acid sequences as shown in SEQ ID NOs: 3-5, respectively; and a light chain variable region of the antibody comprises LCDR1-LCDR3 having amino acid sequences as shown in SEQ ID NOs: 8-10, respectively. The antibody can effectively bind to TIGIT and has the potential for use in tumor prevention and treatment.

Abstract: A corona-resistant enameled round wire and preparation method of making such which is suitable for electric vehicle motors and has a copper conductor and an insulating layer. The insulating layer clads the copper conductor and has in sequence from inside to outside, a corona- resistant polyamideimide coating, a corona-resistant special resin coating, a corona-resistant polyimide coating, a corona-resistant modified silicone resin coating, and a corona-resistant polyamideimide coating.

Abstract: A fusion gene, a recombinant novel coronavirus high-efficiency immune DNA vaccine, a construction method and use thereof are provided. The immune DNA vaccine ZD-nCor19 provided herein uses RBD protein, residues 301-538 in the S2 subunit and residues 138-369 in the N protein of the novel coronavirus as target antigens, and has specific immune synergism molecules introduced at suitable positions, and thus can simultaneously efficiently induce humoral immunity and cellular immunity, and can avoid safety problems associated with ADE that may be generated by the full-length S protein and the full-length N protein, thereby achieving dual effects of prevention and treatment. The vaccine can be used as a safe, efficient and stable vaccine variety against novel coronavirus infection.

Abstract: Technology described herein provides for adapting statistics resolution for 3A algorithms. The technology is to analyze a scene from a plurality of input images to determine a stability score, determine a target imaging statistics resolution based on the stability score, and calculate, using imaging statistics corresponding to the target imaging statistics resolution, an auto exposure parameter and/or an auto white balance parameter. In one aspect, the technology is to generate a multi-scale statistics set including a plurality of sets of imaging statistics, select the target imaging statistics resolution from a predetermined set of resolutions, and select, from the plurality of sets of imaging statistics, a set of imaging statistics corresponding to the target imaging statistics resolution. In another aspect, the technology is to compute the target imaging statistics resolution based on the stability score and a maximum imaging statistics resolution for the computing device.

Abstract: The present application relates to the fields of tumor treatment and molecular immunology, and specifically, to an anti-VEGFA/PD-1 bifunctional antibody, a pharmaceutical composition thereof and use thereof. Specifically, the anti-VEGFA/PD-1 bifunctional antibody comprises a first protein functional region targeting VEGFA and a second protein functional region targeting PD-1. The bifunctional antibody can specifically bind to VEGFA and PD-1, specifically relieve immunosuppression of VEGFA and PD-1 in an organism, and inhibit tumor-induced angiogenesis, thus having good application prospect.