Abstract: Disclosed are an o-phenyl chalcone compounds and preparation methods and uses thereof. The o-phenyl chalcone compounds are capable of inhibiting the aggregation of microtubules in tumor cells and influencing the mitosis of the cells, and have a high antitumor activity. The compounds also have inhibitory activity against proliferation on various tumor cells, such as a human ovary cancer cell A2780, a human colon cancer cell HCT8, a human breast cancer cell MCF7, a human lung cancer cell A549, a human colon cancer cell SW480, a human nasopharyngeal carcinoma cell CNE2, a human liver cancer cell HepG2 and the like at nanomole concentrations.

Abstract: The present disclosure provides a method, a device and a terminal for restoring a firmware program, which pertains to the technical field of electronic devices. The method may be applied in a terminal having an activated first storage region storing a firmware program most recently executed by the terminal and an inactivated second storage region storing a back-up firmware program. The method may include: receiving a signal to restore a firmware program in the terminal; in response to the receiving of the signal to restore the firmware program, deactivating the first storage region and activating the second storage region; and loading in the terminal the back-up firmware program stored in the activated second storage region. The disclosure may solve a problem in the related art that a firmware program can be restored only by using a flash tool, and it may achieve an effect of restoring a firmware program with the use of a single key, and thus facilitate simpler operation of the terminal by the user.

Abstract: Certain aspects of the present disclosure relate to methods and apparatus for adjusting flow rate of transmissions received at a device. A user equipment (UE) determines, in response to detecting a trigger condition, a proposal to adjust feedback provided to a base station (BS) in order to adjust a flow rate of transmissions received at the UE from the BS. The UE adjusts the feedback based on the proposal and at least one additional condition and transmits the adjusted feedback to the BS.

Abstract: A train driving assistance method includes: pre-setting a train traveling line database (S0); acquiring the position of a train (S1); acquiring the position information about the next early-warning point (S2); calculating an early-warning distance between the train and the next early-warning point according to the position of the train and the position information about the next early-warning point (S3); when the early-warning distance is calculated to be smaller than a pre-set value, displaying the early-warning information corresponding to the position information about the next early-warning point (S4); screening an optimal solution according to the train arrival time information and the number brake times of the train (S5); and determining the driving information according to the optimal solution and displaying the determined driving information (S6). Through the method, more driving reference information can be provided for the driver. Also provided is a train driving assistance system.

Abstract: Disclosed are a method, apparatus and system for instant message routing. The method includes: receiving a communication request from a source client to a destination client; acquiring the context associated with the source client and the destination client; and selecting a sub-user of the destination client for communication using a policy according to the context. When a source client requests communication with a virtual user, the method can route the communication request using a policy according to the context, to a sub-user of the virtual user which once communicated with the source client.

Abstract: Synthetic surfaces suitable for culturing stem cell derived oligodendrocyte progenitor cells contain acrylate polymers formed from one or more acrylate monomers. The acrylate surfaces, in many cases, are suitable for culturing stem cell derived oligodendrocyte progenitor cells in chemically defined media.

Abstract: Techniques are disclosed for generating codes for representation of data in memory devices that may avoid the block erasure operation in changing data values. Data values comprising binary digits (bits) can be encoded and decoded using the generated codes, referred to as codewords, such that the codewords may comprise a block erasure-avoiding code, in which the binary digits of a data message m can be encoded such that the encoded data message can be stored into multiple memory cells of a data device and, once a memory cell value is changed from a first logic value to a second logic value, the value of the memory cell may remain at the second logic value, regardless of subsequently received messages, until a block erasure operation on the memory cell.

Abstract: A carpooling server includes a processor; a server communication transceiver that receives pick-up time and location, drop-off location, and window time from a mobile device communication platform, and delay threshold from a participating vehicle (PV) communication platform; and a real-time carpooling program. First filter includes computer readable instructions (CRI) to identify a qualified trip upon determining pick-up time is within a PV trip travel period. Second filter receives a then-current location of the PV associated with the qualified trip, and includes CRI to: estimate an arrival time (ETA) of PV at pick-up location; and identify a potential carpool candidate (PCC) upon determining ETA is within the window time. Third filter includes CRI to: estimate a new end time (ENET) for the PCC by combining the PV then-current location with pick-up/drop-off locations and an original PV destination; and identify a carpool candidate upon determining ENET is within the delay threshold.

Abstract: A hand motion identification method includes: obtaining a to-be-identified video; performing area-locating and tracking of a hand for the to-be-identified video, and extracting a red-green-blue (RGB) video and a depth information video of the hand; detecting the RGB video and the depth information video of the hand, to obtain a feature point; representing the feature point by using a 3D Mesh motion scale-invariant feature transform (MoSIFT) feature descriptor; and comparing the 3D Mesh MoSIFT feature descriptor of the feature point with a 3D Mesh MoSIFT feature descriptor in a positive sample obtained through beforehand training, to obtain a hand motion category in the to-be-identified video.

Abstract: The present disclosure provides systems and methods useful in early detection and assessment of osteoarthritis and other bone-related conditions.

Abstract: A blood component cooling container includes a body portion having a proximal end and a distal end. The body portion defines an interior volume, and includes a plurality of cooling vanes that extend radially outward from the body portion. The cooling vanes increase the external surface area of the blood component cooling container. The blood component cooling container also has an opening within the body portion and configured to receive collected plasma.

Abstract: The present disclosure provides a shift register, a display device, and a method for driving the display device. A pull-down module and a stop module are added in the shift register. When a full screen picture is displayed, the signal output port outputs a high-level signal to the gate line connected with the signal output port, such that the gate line scans the display panel of the display device normally. The pull-down module may maintain the pull-up node and the signal output port at a low-level during the non-working time of the shift register, so as to prevent the shift register from outputting noise. When a local picture is displayed, under the control of the stop signal input port Stop, the stop module outputs the low-level signal to the gate line connected with the signal output port, such that the gate line stops scanning the display panel.

Abstract: The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions. In some embodiments, the FGF21 mutant polypeptide comprises a substitution at position 98, 171 and/or 180.

Abstract: A method for cleaning an internal surface of a narrow diameter channel includes steps of: flowing a liquid cleaning medium and a gas through the narrow diameter channel under a flow regime that creates surface flow entities in contact with and sliding along the internal surface of the narrow diameter channel, the surface flow entities having three-phase contact lines and associated menisci, the surface flow entities detaching contaminants with which they come in contact from the internal surface of the narrow diameter internal surface of the narrow diameter channel; and rinsing the internal surface of the narrow diameter channel to remove residual liquid cleaning medium and detached contaminants from the channel.

Abstract: The present invention relates to an interface and method for enabling interconnection of a host device and a small-formfactor pluggable module. The interface comprises a host device connector operative to receive a mating small-formfactor pluggable module connector and a switching device connected to the host device connector and operative to selectively switch at least one signal carried over the host device connector between at least two separate signal paths of the host device depending on a selected switching mode of the switching device.

Abstract: Methods and kits for selectively enriching non-random polynucleotide sequences are provided. Methods and kits for generating libraries of sequences are provided. Methods of using selectively enriched non-random polynucleotide sequences for detection of fetal aneuploidy are provided.

Abstract: Query requests for RDF triples are obtained, wherein the query request(s) contain(s) at least one triple pattern; for each triple pattern, the corresponding elementary pattern is determined, and each triple pattern is converted to a weighted elementary pattern. The occurrence frequency of each elementary pattern is computed based on the weighted elementary patterns; at least one elementary pattern is chosen at least according to the occurrence frequency; and the RDF triples corresponding to the chosen at least elementary pattern are prefetched into the buffer. The corresponding apparatus is also provided. With the above method and apparatus, the frequently accessed RDF triples can be determined and prefetched into the buffer, which improves the query efficiency.

Abstract: Provided are certain methods useful in the treatment of pain comprising administering a compound of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB2 receptor;

Abstract: The invention provides compositions and methods for determining the fraction of fetal nucleic acids in a maternal sample comprising a mixture of fetal and maternal nucleic acids. The fraction of fetal nucleic acids can be used in determining the presence or absence of fetal aneuploidy.

Abstract: A method for cleaning semiconductor substrate using ultra/mega sonic device comprising holding a semiconductor substrate by using a chuck, positioning a ultra/mega sonic device adjacent to the semiconductor substrate, injecting chemical liquid on the semiconductor substrate and gap between the semiconductor substrate and the ultra/mega sonic device, changing gap between the semiconductor substrate and the ultra/mega sonic device for each rotation of the chuck during the cleaning process by turn the semiconductor substrate or the ultra/mega sonic device clockwise or counter clockwise.