Patents by Inventor Yuegang Zhang

Yuegang Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120165372
    Abstract: Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide are described herein, including crystalline forms thereof.
    Type: Application
    Filed: March 6, 2012
    Publication date: June 28, 2012
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: John DeMattei, Yushi Feng, Cristian Harrison, Adam Looker, Praveen Mudunuri, Stefanie Roeper, Yuegang Zhang
  • Publication number: 20120154983
    Abstract: A method for forming a novel composite of carbon nanofibers grown on a nickel foam is described wherein the composite, when used in a capacitor exhibits superior change retention and discharge capacities. Once the composite material has been obtained, it may be formed into electrodes which can be used to form supercapacitors of large per area capacitances in the order of 1.2 F/cm2.
    Type: Application
    Filed: October 6, 2011
    Publication date: June 21, 2012
    Applicant: The Regents of the University of California
    Inventors: Yuegang Zhang, Yi Cui, James McDonough, Jang Wook Choi
  • Patent number: 8178402
    Abstract: Carbon nanotubes may be selectively opened and their exposed ends functionalized. Opposite ends of carbon nanotubes may be functionalized in different fashions to facilitate self-assembly and other applications.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: May 15, 2012
    Assignee: Intel Corporation
    Inventor: Yuegang Zhang
  • Patent number: 8173436
    Abstract: Systems and methods for detecting the presence of biomolecules in a sample using biosensors that incorporate resonators which have functionalized surfaces for reacting with target biomolecules. In one embodiment, a device includes a piezoelectric resonator having a functionalized surface configured to react with target molecules, thereby changing the mass and/or charge of the resonator which consequently changes the frequency response of the resonator. The resonator's frequency response after exposure to a sample is compared to a reference, such as the frequency response before exposure to the sample, a stored baseline frequency response or a control resonator's frequency response.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: May 8, 2012
    Assignee: Intel Corporation
    Inventors: Yuegang Zhang, Andrew Berlin, Qing Ma, Li-Peng Wang, Valluri Rao, Mineo Yamakawa
  • Patent number: 8163772
    Abstract: Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide are described herein, including crystalline forms thereof.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: April 24, 2012
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: John DeMattei, Yushi Feng, Cristian Harrison, Adam Looker, Praveen Mudunuri, Stefanie Roeper, Yuegang Zhang
  • Publication number: 20110269299
    Abstract: A substrate is provided that has a metallic layer on a substrate surface of a substrate. A film made of a two dimensional (2-D) material, such as graphene, is deposited on a metallic surface of the metallic layer. The metallic layer is dewet and/or removed to provide the film on the substrate surface.
    Type: Application
    Filed: May 2, 2011
    Publication date: November 3, 2011
    Applicant: The Regents of the University of California
    Inventors: Yuegang Zhang, Ariel Ismach
  • Publication number: 20110251253
    Abstract: The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith.
    Type: Application
    Filed: March 25, 2011
    Publication date: October 13, 2011
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Ali Keshavarz-Shokri, Beili Zhang, Tim Edward Alcacio, Elaine Chungmin Lee, Yuegang Zhang, Mariusz Krawiec
  • Patent number: 7985627
    Abstract: Apparatus and system, as well as fabrication methods therefor, may include a thermal intermediate structure comprised of a plurality of carbon nanotubes some of which have organic moieties attached thereto to tether the nanotubes to at least one of a die and a heat sink. The organic moieties include thiol linkers and amide linkers.
    Type: Grant
    Filed: November 24, 2008
    Date of Patent: July 26, 2011
    Assignee: Intel Corporation
    Inventors: Bryan M. White, Paul A. Koning, Yuegang Zhang, C. M. Garner
  • Publication number: 20110086438
    Abstract: Systems and methods for detecting the presence of biomolecules in a sample using biosensors that incorporate resonators which have functionalized surfaces for reacting with target biomolecules. In one embodiment, a device includes a piezoelectric resonator having a functionalized surface configured to react with target molecules, thereby changing the mass and/or charge of the resonator which consequently changes the frequency response of the resonator. The resonator's frequency response after exposure to a sample is compared to a reference, such as the frequency response before exposure to the sample, a stored baseline frequency response or a control resonator's frequency response.
    Type: Application
    Filed: December 14, 2010
    Publication date: April 14, 2011
    Inventors: Yuegang ZHANG, Andrew BERLIN, Qing MA, Li-Peng WANG, Valluri RAO, Mineo YAMAKAWA
  • Patent number: 7914740
    Abstract: Systems and methods for detecting the presence of biomolecules in a sample using biosensors that incorporate resonators which have functionalized surfaces for reacting with target biomolecules. In one embodiment, a device includes a piezoelectric resonator having a functionalized surface configured to react with target molecules, thereby changing the mass and/or charge of the resonator which consequently changes the frequency response of the resonator. The resonator's frequency response after exposure to a sample is compared to a reference, such as the frequency response before exposure to the sample, a stored baseline frequency response or a control resonator's frequency response.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: March 29, 2011
    Assignee: Intel Corporation
    Inventors: Yuegang Zhang, Andrew A. Berlin, Qing Ma, Li-Peng Wang, Valluri Rao, Mineo Yamakawa
  • Publication number: 20110059987
    Abstract: The invention relates to compositions and co-crystals each comprising VX-950 and a co-crystal former selected from the group consisting of 4-hydroxybenzoic acid, 4-amino salicylic acid, phenylalanine, threonline, tartaric acid, adipic acid, succinic acetate, proline, methyl 4-hydroxybenzoate, anthranilic acid, and d-Biotin. Also within the scope of this invention are methods of making and using the same.
    Type: Application
    Filed: February 27, 2008
    Publication date: March 10, 2011
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Patrick R. Connelly, Irina Kadiyala, Kathy Stavropolus, Yuegang Zhang, Steve Johnston, Govinda Rao Bhisetti, Valdas Jurkauskas, Peter Rose
  • Patent number: 7871569
    Abstract: Systems and methods for detecting the presence of biomolecules in a sample using biosensors that incorporate resonators which have functionalized surfaces for reacting with target biomolecules. In one embodiment, a device includes a piezoelectric resonator having a functionalized surface configured to react with target molecules, thereby changing the mass and/or charge of the resonator which consequently changes the frequency response of the resonator. The resonator's frequency response after exposure to a sample is compared to a reference, such as the frequency response before exposure to the sample, a stored baseline frequency response or a control resonator's frequency response.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: January 18, 2011
    Assignee: Intel Corporation
    Inventors: Yuegang Zhang, Andrew A. Berlin, Qing Ma, Li-Peng Wang, Valluri Rao, Mineo Yamakawa
  • Publication number: 20110009424
    Abstract: The invention relates to co-crystals and compositions each comprising VX-950 and a co-crystal former selected from the group consisting of 3-methoxy-4-hydroxybenzoic acid, 2,4-dihydroxybenzoic acid, and 2,5-dihydroxybenzoic acid. Also within the scope of this invention are methods of making and using the same.
    Type: Application
    Filed: August 29, 2008
    Publication date: January 13, 2011
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Yuegang Zhang, Patrick R. Connelly, Steve Johnston
  • Patent number: 7795035
    Abstract: According to some embodiments, a method, a system, and an apparatus to determine a concentration of carbon nanotubes in a solution. In some embodiments, the method includes determining a photoluminescence intensity of a solution, mixing a sample of carbon nanotubes of an unknown concentration with the solution, determining a photoluminescence intensity of the mixture of the sample of carbon nanotubes and the solution, and determining a concentration of carbon nanotubes in the sample of carbon nanotubes based on the determined photoluminescence intensity of the mixture of the sample of carbon nanotubes and the solution.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: September 14, 2010
    Assignee: Intel Corporation
    Inventors: Yuegang Zhang, Shida Tan, Herman Lopez
  • Publication number: 20100151454
    Abstract: Disclosed herein are methods, apparatuses, and systems for performing nucleic acid sequencing reactions and molecular binding reactions in a microfluidic channel. The methods, apparatuses, and systems can include a restriction barrier to restrict movement of a particle to which a nucleic acid is attached. Furthermore, the methods, apparatuses, and systems can include hydrodynamic focusing of a delivery flow. In addition, the methods, apparatuses, and systems can reduce non-specific interaction with a surface of the microfluidic channel by providing a protective flow between the surface and a delivery flow.
    Type: Application
    Filed: October 22, 2008
    Publication date: June 17, 2010
    Inventors: Narayanan Sundararajan, Lei Sun, Yuegang Zhang, Xing Su, Selena Chan, Tae-Woong Koo, Andrew A. Berlin
  • Patent number: 7692249
    Abstract: Carbon nanotubes may be selectively opened and their exposed ends functionalized. Opposite ends of carbon nanotubes may be functionalized in different fashions to facilitate self-assembly and other applications.
    Type: Grant
    Filed: January 21, 2004
    Date of Patent: April 6, 2010
    Assignee: Intel Corporation
    Inventor: Yuegang Zhang
  • Publication number: 20100063284
    Abstract: Solid forms of crystalline1-ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1H-benzo[d]imidazol-2-yl)urea, compositions containing solid forms of crystalline1-ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1H-benzo[d]imidazol-2-yl)urea and methods of using the same are described.
    Type: Application
    Filed: December 5, 2008
    Publication date: March 11, 2010
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Rossitza Alargova, Irina Kadiyala, Arnaud Le Tiran, Dainius Macikenas, Yuegang Zhang
  • Patent number: 7629639
    Abstract: An embodiment is a transistor for non-volatile memory that combines nanocrystal and nanotube paradigm shifts. In particular an embodiment is a transistor-based non-volatile memory element that utilizes a carbon nanotube channel region and nanocrystal charge storage regions. Such a combination enables a combination of low power, low read and write voltages, high charge retention, and high bit density. An embodiment further exhibits a large memory window and a single-electron drain current.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: December 8, 2009
    Assignee: Intel Corporation
    Inventors: Yuegang Zhang, Udayan Ganguly, Edwin Kan
  • Publication number: 20090170725
    Abstract: The methods, apparatus and systems disclosed herein concern ordered arrays of carbon nanotubes. In particular embodiments of the invention, the nanotube arrays are formed by a method comprising attaching catalyst nanoparticles 140, 230 to polymer 120, 210 molecules, attaching the polymer 120, 210 molecules to a substrate, removing the polymer 120, 210 molecules and producing carbon nanotubes on the catalyst nanoparticles 140, 230. The polymer 120, 210 molecules can be attached to the substrate in ordered patterns, using self-assembly or molecular alignment techniques. The nanotube arrays can be attached to selected areas 110, 310 of the substrate. Within the selected areas 110, 310, the nanotubes are distributed non-randomly. Other embodiments disclosed herein concern apparatus that include ordered arrays of nanotubes attached to a substrate and systems that include ordered arrays of carbon nanotubes attached to a substrate, produced by the claimed methods.
    Type: Application
    Filed: January 31, 2006
    Publication date: July 2, 2009
    Inventors: Mineo Yamakawa, Yuegang Zhang, Xing Su, Lei Sun, Andrew A. Berlin, Narayanan Sundararajan
  • Publication number: 20090169466
    Abstract: The methods, apparatus and systems disclosed herein concern ordered arrays of carbon nanotubes. In particular embodiments of the invention, the nanotube arrays are formed by a method comprising attaching catalyst nanoparticles 140, 230 to polymer 120, 210 molecules, attaching the polymer 120, 210 molecules to a substrate, removing the polymer 120, 210 molecules and producing carbon nanotubes on the catalyst nanoparticles 140, 230. The polymer 120, 210 molecules can be attached to the substrate in ordered patterns, using self-assembly or molecular alignment techniques. The nanotube arrays can be attached to selected areas 110, 310 of the substrate. Within the selected areas 110, 310, the nanotubes are distributed non-randomly. Other embodiments disclosed herein concern apparatus that include ordered arrays of nanotubes attached to a substrate and systems that include ordered arrays of carbon nanotubes attached to a substrate, produced by the claimed methods.
    Type: Application
    Filed: January 31, 2006
    Publication date: July 2, 2009
    Inventors: Mineo Yamakawa, Yuegang Zhang, Xing Su, Lei Sun, Andrew A. Berlin, Narayanan Sundararajan