Abstract: In a fixing device, a heating section is disposed opposite to an inner circumferential surface of a fixing belt, and includes a heater, a heater holding member, a reinforcing member extending in a rotation axis of the pressure member, a heat sensitive body disposed on the heater holding member, and an urging member disposed between the reinforcing member and the heat sensitive body. The heater holding member includes an engaging portion engaging with a first end of the reinforcing member. In a state in which the reinforcing member is located opposite to the heater holding member through the reinforcing member turning about the engaging portion as a pivot, the urging member urges the heat sensitive body against the heater and a distance between the heat sensitive body and a second end of the reinforcing member is shorter than a distance between the heat sensitive body and the first end.

Abstract: In a fixing device, a heating section is disposed opposite to an inner circumferential surface of a fixing belt. The heating section includes a heater, a heater holding member, a heat sensitive body disposed opposite to the heater on the heater holding member, a covering member disposed opposite to the heater holding member with the heat sensitive body therebetween, and an urging member disposed between the covering member and the heat sensitive body and urging the heat sensitive body in an urging direction. First and second restricting portions of the heater holding member restrict movement of the covering member in a direction opposite to the urging direction. In a state in which first and second engaging portions of the covering member respectively engage with the first and second restricting portions in a slidable manner in the urging direction, the urging member urges the heat sensitive body in the urging direction.

Abstract: A fixing device includes a fixing belt and a heating section. The heating section is disposed opposite to an inner circumferential surface of the fixing belt. The heating section includes a heater, a heater holding member, and a pinching member. The heater heats the fixing belt. The heater holding member holds the heater. The pinching member pinches the heater and the heater holding member to restrict movement of the heater relative to the heater holding member.

Abstract: A fixing device includes a cylindrical rotatable fixing belt, a flat heater, a heater holding part, a pressuring member, and a connector. In the flat heater, an electrode part, a feeder and a heat generating part are formed in the same face state. The heater holding part holds the flat heater so that the heat generating part faces to an inner circumference face of the fixing belt. The pressuring member sandwiches the fixing belt with the flat heater. The connector has a contacting portion coming into contact with the electrode part. The feeder has a portion arranged at a near side from the electrode part in an attaching direction of the connector. The heater holding part includes a protecting portion covering the portion of the feeder arranged at the near side from the electrode part.

Abstract: A fixing device includes a cylindrical rotatable fixing belt, a flat heater, a safety device, a heater holding part and a pressuring member. The flat heater has a plurality of heat generating parts. The safety device is arranged across two adjacent heat generating parts to interrupt power supply to the heat generating parts in a case where temperature reaches a threshold value. The heater holding part holds the flat heater so that the flat heater comes into contact with an inner circumference face of the fixing belt. The pressuring member sandwiches the fixing belt with the flat heater to form a pressuring area for sandwiching and conveying a sheet between the fixing belt and the pressuring roller.

Abstract: A fixing device includes a cylindrical rotatable fixing belt, a flat heater, a heater holding part, a pressuring member, and a connector. In the flat heater, an electrode part, a feeder and a heat generating part are formed in the same face state. The heater holding part holds the flat heater so that the heat generating part faces to an inner circumference face of the fixing belt. The pressuring member sandwiches the fixing belt with the flat heater. The connector has a contacting portion coming into contact with the electrode part. The feeder has a portion arranged at a near side from the electrode part in an attaching direction of the connector. The heater holding part includes a protecting portion covering the portion of the feeder arranged at the near side from the electrode part.

Abstract: A heating unit includes a circuit board, a plurality of heating parts, and a plurality of wiring parts. The heating parts are arranged in a first direction on a surface of the circuit board. The wiring parts are provided on the surface of the circuit board and electrically connect the heating parts and a power source to feed the heating parts. The wiring parts respectively include electrode terminal parts electrically connected to the power source outside the heating parts in the first direction. Sizes in a second direction orthogonal to the first direction of the heating parts are set to decrease gradually or stepwisely with separating in the first direction from the electrode terminal parts.

Abstract: A heating unit includes a circuit board, heating parts, and electrode parts. The heating parts are arranged in a first direction on a surface of the circuit board. The electrode parts are disposed on the surface of the circuit board, and electrically connected to both sides of the heating parts in a second direction that is orthogonal to the first direction. Each of the heating parts includes a plurality of heating resistors that is arranged in the first direction. Each of the heating resistors has a size ratio of a first length in the second direction to a second length in the first direction is 1 or more and 100 or less.

Abstract: A heating unit includes a circuit board, a plurality of heating parts, and a plurality of wiring parts. The heating parts are arranged in a first direction on a surface of the circuit board. The wiring parts are provided on the surface of the circuit board and electrically connect the heating parts and a power source to feed the heating parts. The wiring parts respectively include electrode terminal parts electrically connected to the power source outside the heating parts in the first direction. Sizes in a second direction orthogonal to the first direction of the heating parts are set to decrease gradually or stepwisely with separating in the first direction from the electrode terminal parts.

Abstract: Provided is a tissue regeneration construct having a good engraftment property and capable of promoting a stable and favorable regeneration to a target site, the tissue regeneration construct being a member to be applied to a target site for transplantation and regeneration to regenerate tissue, including a transplant body, and an engraftment layer arranged overlapping at least a part of an outer surface of the transplant body, wherein: the transplant body includes a support, cells for regenerating the tissue that are arranged at least either one of a space between the supports and a space formed by a pore inside the support, and a base material for retaining the cells; the base material of the engraftment layer is gelatinous; and the engraftment layer is a layer in which the support does not exist.

Abstract: The fixing device includes a fixing member, a pressing member, and a heat source. The fixing member heats toner on a medium. The pressing member forms a pressing area with the fixing member and presses the toner. The heat source is provided corresponding to the pressing area across the fixing member and heats the fixing member. The heat source includes a heat insulation layer and a heating and contacting part. The heat insulation layer is laminated on a base material and has a convex part that protrudes toward the fixing member. The heating and contacting part is laminated on the heat insulation layer that has the convex part and contacts to an inner surface of the fixing member so as to heat the fixing member. The convex part protrudes the heating and contacting part laminated thereon toward the fixing member so as to maximize pressure in the pressing area.

Abstract: A heating unit includes a circuit board, heating parts, and electrode parts. The heating parts are arranged in a first direction on a surface of the circuit board. The electrode parts are disposed on the surface of the circuit board, and electrically connected to both sides of the heating parts in a second direction that is orthogonal to the first direction. Each of the heating parts includes a plurality of heating resistors that is arranged in the first direction. Each of the heating resistors has a size ratio of a first length in the second direction to a second length in the first direction is 1 or more and 100 or less.

Abstract: A fixing device includes a pressuring member, a fixing frame, a pressuring frame, a pressure changing part, a rotation detecting part and a rotation transmitting part. The pressuring member forms a fixing nip with a fixing member. The fixing frame supports the fixing member. The pressuring frame supports the pressuring member. The pressure changing part changes fixing nip pressure. The rotation transmitting part transmits rotation of the pressuring member to the rotation detecting part. The fixing frame is turnably supported around a fulcrum part provided on the pressuring frame. The pressure changing part turns the fixing frame around the fulcrum part. The rotation transmitting part has a first rotating body and a second rotating body. The first rotating body is provided on a rotation shaft of the pressuring member. The second rotating body is engaged with the first rotating body and rotatably supported around the fulcrum part.

Abstract: A fixing device includes a pressuring member, a fixing frame, a pressuring frame, a pressure changing part, a rotation detecting part and a rotation transmitting part. The pressuring member forms a fixing nip with a fixing member. The fixing frame supports the fixing member. The pressuring frame supports the pressuring member. The pressure changing part changes fixing nip pressure. The rotation transmitting part transmits rotation of the pressuring member to the rotation detecting part. The fixing frame is turnably supported around a fulcrum part provided on the pressuring frame. The pressure changing part turns the fixing frame around the fulcrum part. The rotation transmitting part has a first rotating body and a second rotating body. The first rotating body is provided on a rotation shaft of the pressuring member. The second rotating body is engaged with the first rotating body and rotatably supported around the fulcrum part.

Abstract: To provide a bone tissue regeneration sheet having a cortical bone tissue layer of 200 ?m or more in thickness, the bone tissue regeneration sheet is produced by seeding chondroblast or stem cells for differentiating to chondrocyte on one side of a porous bioabsorbable polymer sheet, taking the seeded porous body into a culture medium, applying centrifugal force of 100 to 1000 G to the culture medium for a predetermined time so as to aggregate the chondroblast or the stem cells for differentiating to chondrocyte, culturing the aggregated cells in a culture medium not containing serum but containing one or two or more kinds selected from ascorbic acid, an ascorbic acid derivative, and dexamethasone without applying centrifugal force to form a chondrocyte layer having a thickness of 200 ?m or more.

Abstract: Provided is a tissue regeneration construct having a good engraftment property and capable of promoting a stable and favorable regeneration to a target site, the tissue regeneration construct being a member to be applied to a target site for transplantation and regeneration to regenerate tissue, including a transplant body, and an engraftment layer arranged overlapping at least a part of an outer surface of the transplant body, wherein: the transplant body includes a support, cells for regenerating the tissue that are arranged at least either one of a space between the supports and a space formed by a pore inside the support, and a base material for retaining the cells; the base material of the engraftment layer is gelatinous; and the engraftment layer is a layer in which the support does not exist.

Abstract: For easily seeding cells in its scaffold, a porous cell scaffold is produced by steps of filling a guiding solution with kinematic viscosity being 50 to 450% of that of a culture medium, in a whole continuous small hole structure having hole diameters of 5 to 3200 ?m and an average hole diameter of 50 to 1500 ?m, of a sheet-shaped or block-shaped scaffold having a thickness of 2 mm or more, supplying thereafter a culture medium with cells being suspended to an upper side of the scaffold, sucking the guiding solution from a lower side of the scaffold by low suction force, and entering thereby the culture medium with cells being suspended into the whole small hole structure, where a water absorber such as a filter paper is preferably used for sucking the guiding solution by low suction force.

Abstract: To efficiently select and proliferate the mesenchymal stem cells without necessity of an exclusive separating device and a complicated separating operation, mesenchymal stem cells are cultured by seeding at least one of a bone marrow solution, an umbilical cord blood, a peripheral blood, a synovial membrane and an amniotic membrane in a liquid culture medium which is filled in a vessel, includes water as its main components and having a specific gravity between 1.06 and 1.10 at 37° C., and making a culture at a temperature 37±2° C. on a ceiling side surface of the vessel, preferably the specific gravity being regulated by use of at least one selected from silica fine powder coated by polyvinyl pyrrolidone, a water soluble copolymer of sucrose and epichlorohydrin, and a water soluble compound including a triiodo aromatic ring.

Abstract: To efficiently select and proliferate the mesenchymal stem cells without necessity of an exclusive separating device and a complicated separating operation, mesenchymal stem cells are cultured by seeding at least one of a bone marrow solution, an umbilical cord blood, a peripheral blood, a synovial membrane and an amniotic membrane in a liquid culture medium which is filled in a vessel, includes water as its main components and having a specific gravity between 1.06 and 1.10 g/ml at 37° C., and making a culture at a temperature 37±2° C. on a ceiling side surface of the vessel, preferably the specific gravity being regulated by use of at least one selected from silica fine powder coated by polyvinyl pyrrolidone, a water soluble copolymer of sucrose and epichlorohydrin, and a water soluble compound including a triiodo aromatic ring.

Abstract: To provide a bone graft substitute having an appropriate absorption period in a living body and high osteoconductivity, the bone graft substitute contains a carbonate apatite and an osteoinductive factor, the osteoinductive factor is preferably at least one kind selected from a group including BMP (a bone morphogenetic protein), GDF (a growth differentiation factor), TGF-? (a transformation growth factor), FGF (a fibroblast growth factor), IGF (an insulin-like growth factor), PDGF (a platelet-derived growth factor), BDNF (a brain-derived nerve growth factor), and NGF (a nerve growth factor), and the bone graft substitute has open pores, preferably having a diameter of 50 to 1000 ?m and/or a diameter of 0.001 to 5 ?m, with porosity of 20 to 80%.