Patents by Inventor Yuji Shishido

Yuji Shishido has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200230123
    Abstract: The present invention relates to biaryloxy derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage gated sodium channel is involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which voltage gated sodium channels are involved.
    Type: Application
    Filed: August 31, 2018
    Publication date: July 23, 2020
    Applicants: RaQualia Pharma Inc., XuanZhu Pharma Co., Ltd.
    Inventors: Kiyoshi KAWAMURA, Tatsuya YAMAGISHI, Yuji SHISHIDO, Mikio MORITA, Ryuichi YAMAGUCHI, Masashi OHMI
  • Publication number: 20200025443
    Abstract: The present invention aims to provide a method and an apparatus for producing a lyophilized body, each of which can achieve energy saving, low cost, and a reduction in processing time and can provide a lyophilized body less damaged by a freezing process and a drying process. The present invention relates to a method for lyophilizing a substance using an electromagnetic wave, and the lyophilization method includes freezing the substance under irradiation of at least an electromagnetic wave and reduced-pressure drying the frozen substance under irradiation of at least an electromagnetic wave.
    Type: Application
    Filed: April 2, 2018
    Publication date: January 23, 2020
    Applicant: NITTO DENKO CORPORATION
    Inventors: Chie MATSUMOTO, Takao YOSHIKAWA, Takuya SHISHIDO, Yuji TOYOTA, Sachiko SAKAMOTO, Yoshimitsu SHIMOMURA, Mitsuhiko HORI
  • Publication number: 20200016135
    Abstract: The present invention relates to amide derivatives which have blocking activities of voltage gated sodium channels as the Nav1.7 and Nav1.8 channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage gated sodium channels are involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which voltage gated sodium channels are involved.
    Type: Application
    Filed: June 20, 2018
    Publication date: January 16, 2020
    Applicant: RaQualia Pharma Inc.
    Inventors: Tatsuya YAMAGISHI, Mikio MORITA, Yuji SHISHIDO, Ryuichi YAMAGUCHI, Norikazu GAJA
  • Publication number: 20180339993
    Abstract: The present invention relates to azaspiro derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor,
    Type: Application
    Filed: July 31, 2018
    Publication date: November 29, 2018
    Applicant: RaQualia Pharma Inc.
    Inventors: Yuji SHISHIDO, Masashi OHMI, Kazuo ANDO
  • Publication number: 20180305341
    Abstract: The present invention relates to imidazolinone derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor.
    Type: Application
    Filed: September 12, 2016
    Publication date: October 25, 2018
    Applicant: RaQualia Pharma Inc.
    Inventors: Yuji SHISHIDO, Masashi OHMI
  • Patent number: 10093678
    Abstract: The present invention relates to azaspiro derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: October 9, 2018
    Assignee: RaQualia Pharma Inc.
    Inventors: Yuji Shishido, Masashi Ohmi, Kazuo Ando
  • Publication number: 20170002016
    Abstract: The present invention relates to azaspiro derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor.
    Type: Application
    Filed: March 16, 2015
    Publication date: January 5, 2017
    Applicant: RaQualia Pharma Inc.
    Inventors: Yuji SHISHIDO, Masashi OHMI, Kazuo ANDO
  • Patent number: 8829026
    Abstract: The present invention relates to sulfamoyl benzoic acid heterobicyclic derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPMb8 receptor.
    Type: Grant
    Filed: October 3, 2011
    Date of Patent: September 9, 2014
    Assignee: RaQualia Pharma Inc.
    Inventors: Kiyoshi Kawamura, Yuji Shishido, Masashi Ohmi
  • Publication number: 20130210858
    Abstract: The present invention relates to sulfamoyl benzoic acid heterobicyclic derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor.
    Type: Application
    Filed: October 3, 2011
    Publication date: August 15, 2013
    Applicant: Raqualia Pharma Inc.
    Inventors: Kiyoshi Kawamura, Yuji Shishido, Masashi Ohmi
  • Patent number: 8252790
    Abstract: Disclosed is a compound represented by general formula (I) or a pharmaceutically acceptable salt thereof, which is useful as a selective antagonist of a 5-HT2B receptor. The compound and salt are useful for treatment or prevention of various diseases and conditions associated with a 5-HT2B receptor.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: August 28, 2012
    Assignee: Raqualia Pharma Inc.
    Inventors: Tatsuya Yamagishi, Kiyoshi Kawamura, Tadashi Inoue, Yuji Shishido, Hiroaki Ito
  • Patent number: 8178558
    Abstract: This invention relates to novel substituted pyridylmethyl bicyclocarboxamide compounds and to their use in therapy. These compounds are particularly useful as modulators of the VR1 (Type I Vanilloid) receptor, and are thus useful for the treatment of pain, neuralgia, neuropathies, nerve injury, burns, migraine, carpal tunnel syndrome, fibromyalgia, neuritis, sciatica, pelvic hypersensitivity, bladder disease, inflammation, or the like in mammals, especially humans.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: May 15, 2012
    Assignee: Pfizer Inc.
    Inventors: Satoshi Nagayama, Yuji Shishido, Hirotaka Tanaka
  • Publication number: 20120094964
    Abstract: The present invention relates to sulfamoyl benzoic acid derivatives of formula (I) or a pharmaceutically acceptable salt thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor.
    Type: Application
    Filed: May 6, 2010
    Publication date: April 19, 2012
    Inventors: Tadashi Inoue, Masashi Ohmi, Kiyoshi Kawamura, Kazuo Ando, Yuji Shishido
  • Publication number: 20120088746
    Abstract: Compounds are disclosed that have a formula represented by the following: Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: May 10, 2007
    Publication date: April 12, 2012
    Applicants: PFIZER INC., RENOVIS, INC.
    Inventors: Yuji Shishido, Kazunari Nakao, Satoshi Nagayama, Hirotaka Tanaka, Matthew Alexander James Duncton, Matthew Cox, John Kincaid, Kiran Sahasrabudhe, Maria de Los Angeles Estiarte-Martinez
  • Patent number: 8153651
    Abstract: Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: April 10, 2012
    Assignee: Evotec AG
    Inventors: Matthew Cox, Donogh John Roger O'Mahony, Maria De Los Angeles Estiarte-Martinez, Tadashi Kawashima, Satoshi Nagayama, Yuji Shishido, Hirotaka Tanaka, Matthew Alexander James Duncton, Andrew Antony Calabrese
  • Publication number: 20110275628
    Abstract: Disclosed is a compound represented by general formula (I) or a pharmaceutically acceptable salt thereof, which is useful as a selective antagonist of a 5-HT2B receptor. The compound and salt are useful for treatment or prevention of various diseases and conditions associated with a 5-HT2B receptor.
    Type: Application
    Filed: November 24, 2009
    Publication date: November 10, 2011
    Inventors: Tatsuya Yamagishi, Kiyoshi Kawamura, Tadashi Inoue, Yuji Shishido, Hiroaki Ito
  • Publication number: 20110115324
    Abstract: A bearing unit is provided which includes a shaft (51) to support rotatably, radial bearing (55) to support the shaft (51) circumferentially, a thrust bearing (66) to support the shaft (51) in the direction of thrusting, and a housing (56) having the radial bearing (55) and thrust bearing (66) disposed therein and in which a viscous fluid (57) is filled. The housing (56) has a sealed structure except for a shaft insertion hole (65) formed therein and through which the shaft 51 is introduced. Between the outer surface of the shaft (51) and the inner surface of the shaft insertion hole (65), there is defined a gap (69) having a sufficient width to prevent the viscous fluid (57) filled in the housing (56) from leaking out of the latter.
    Type: Application
    Filed: December 9, 2010
    Publication date: May 19, 2011
    Applicant: SONY CORPORATION
    Inventors: Yuji Shishido, Kenichiro Yazawa, Shinichiro Kato, Shuichi Kikuchi, Toru Ujiie
  • Patent number: 7915448
    Abstract: This invention provides a compound of the formula (I): wherein A and B are independently CR12 or N; D and E are each independently CR9 or N; R1 represents (C1-C6)alkyl; R2 represents hydrogen, halogen, hydroxy, (C1-C6) alkyl, halo(C1-C6) alkyl, hydroxy(C1-C6) alkyl, (C1-C6)alkoxy or (C1-C6)alkoxy-(C1-C6)alkyl; R3, R4, R5, R6, R10 and R11 each independently represent hydrogen, halogen, (C1-C6)alkyl, halo(C1-C6)alkyl, (C1-C6)alkoxy, hydroxy(C1-C6)alkyl or (C1-C6)alkoxy-(C1-C6)alkyl; or R3 and R4 are taken together with the carbon atom to which they are attached to form a 3- to 7-membered carbocyclic ring or heterocyclic ring in which one or two non-adjacent carbon atoms are optionally replaced by an oxygen atom, a sulfur atom or NH; R7 and R9 each independently represent hydrogen, halogen, (C1-C6)alkyl, halo(C1-C6)alkyl, hydroxy(C1-C6)alkyl, (C1-C6)alkoxy, hydroxy(C1-C6)alkoxy, (C1-C6)alkoxy-(C1-C6)alkyl, (C1-C6)alkoxy-(C1-C6)alkoxy, (C1-C6)alkylthio, (C1-C6)alkylsulfinyl, (C1-C6)alkylsulfonyl, NH2, [(C1-C6
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: March 29, 2011
    Assignee: Pfizer Inc.
    Inventors: Takeshi Hanazawa, Misato Hirano, Tadashi Inoue, Satoshi Nagayama, Kazunari Nakao, Yuji Shishido, Hirotaka Tanaka
  • Patent number: 7885065
    Abstract: Provided is a fan motor apparatus. The fan motor apparatus includes a rotor and a stator. The rotor includes a blade. The stator includes a rotor supporting mechanism, a supporting member, and a vibration insulation member. The rotor supporting mechanism rotatably supports the rotor. The supporting member supports the rotor supporting mechanism. The vibration insulation member is provided between the rotor supporting mechanism and the supporting member. The stator is capable of regulating relative movement of the rotor supporting mechanism and the supporting member.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: February 8, 2011
    Assignee: Sony Corporation
    Inventors: Sachiko Kaneko, Yuji Shishido, Takashi Mochida, Hideo Niikura, Atsushi Kikuchi, Makoto Chiyoda
  • Patent number: 7882512
    Abstract: An automatic balancing apparatus is disclosed. The automatic balancing apparatus includes a housing, magnetic fluid, and a plurality of balancers. The housing is rotatable. The magnetic fluid is contained in the housing. Each of the plurality of balancers is movable in the housing and has a magnet and a yoke which is mounted thereto and which has a raised portion or a depressed portion formed on an inner circumferential side of a rotation of the housing.
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: February 1, 2011
    Assignee: Sony Corporation
    Inventors: Rikuhiro Hanai, Takashi Mochida, Yuji Shishido
  • Publication number: 20110021514
    Abstract: Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: November 13, 2008
    Publication date: January 27, 2011
    Applicants: RENOVIS, INC., PFIZER GLOBAL RESEARCH AND DEVELOPMENT
    Inventors: Matthew Cox, Donogh John Roger O'Mahony, Maria De Los Angeles Estiarte-Martinez, Tadashi Kawashima, Satoshi Nagayama, Yuji Shishido, Hirotaka Tanaka, Matthew Alexander James Duncton, Andrew Antony Calabrese