Abstract: The present invention provides a cell cultivation method that includes: (1) a step in which a first culture medium including suspended cells is applied to a cell cultivation module; (2) a step in which a temperature at which cell cultivation is possible is maintained, and the cells are made to adsorb to the cell cultivation module; and (3) a step in which the cell cultivation module to which the cells are adsorbed is cultivated within a culture vessel with a second culture medium, wherein a polymer porous film is a polymer porous film with a three-layer structure, having a surface layer A and a surface layer B that have a plurality of holes, and a macrovoid layer that is sandwiched between the surface layer A and the surface layer B, the average hole diameter of the holes present in the surface layer A is smaller than the average hole diameter of the holes present in the surface layer B, the macrovoid layer has dividing walls that are connected to the surface layers A and B, and a plurality of macrovoids that

Abstract: The present invention provides a cell cultivation device comprising: a polymer porous film; a cell cultivation part that accommodates the polymer porous film; a culture medium supply means that is positioned at an upper section of the cell cultivation part; and a culture medium recovery means that is positioned at a lower section of the cell cultivation part, wherein the polymer porous film is a polymer porous film with a three-layer structure, having a surface layer A and a surface layer B that have a plurality of holes, and a macrovoid layer that is sandwiched between the surface layer A and the surface layer B, the average hole diameter of the holes present in the surface layer A is smaller than the average hole diameter of the holes present in the surface layer B, the macrovoid layer has dividing walls that are connected to the surface layers A and B, and a plurality of macrovoids that are surrounded by the dividing walls and the surface layers A and B, the holes in the surface layers A and B are in commu

Abstract: Provided is an oral cleaning device capable of ensuring a sufficient ejection pressure for a cleaning liquid while employing a small and low-cost electric air pump with a low output. An oral cleaning device is provided with an air-tightly closable cleaning liquid tank 2 which stores a cleaning liquid, a cleaning liquid supply passage 24 which has an ejection port 4a for ejecting the cleaning liquid into the oral cavity on one end and an introduction port 23a open inside the bottom part of the cleaning liquid tank 2 on the other end, and an electric air pump 44 which supplies air into the cleaning liquid tank 2 to pressurize the inside of the cleaning liquid tank 2. The cleaning liquid inside the cleaning liquid tank 2 is supplied to the ejection port 4a through the cleaning liquid supply passage 24 by air pressure inside the cleaning liquid tank 2.

Abstract: The invention relates to a long term cell culturing method and a cell culturing apparatus and kit that employ a porous polyimide film. The invention further relates to a cell cryopreservation method and kit employing the porous polyimide film.

Abstract: The present invention pertains to a method for the mass cultivation of cells, and a cell cultivation device and kit. The present invention further pertains to a continuous cell cultivation method and a continuous cell cultivation device in which a carrier is used.

Abstract: The present invention relates to a cell culturing method and kit. More specifically, it relates to a cell culturing method and kit using a support that is exposed to the air. It further relates to a method of culturing cells by allowing them to migrate onto a porous polyimide film.

Abstract: The purpose of the present invention is to provide a method for isolating, removing and analyzing cells. Provided is a method for isolating, removing and analyzing cells by filtering a liquid specimen containing cells through a porous polyimide film, and subjecting the cells captured by the film which did not pass through the porous polyimide film, or the cells in the liquid specimen which did pass through the porous polyimide film, to an examination of one or more cell properties selected from a group consisting of cell number or type, internal or external cell structure, type or amount of cell surface antigen, type or amount of material secreted from cells, cell adhesion, and cell survival rate.

Abstract: The present invention pertains to a method for the mass cultivation of cells, and a cell cultivation device and kit. The present invention further pertains to a continuous cell cultivation method and a continuous cell cultivation device in which a carrier is used.

Abstract: The present invention relates to a method of using cells to produce a substance, and involves applying the cells to a polyimide porous film, culturing the cells and producing the substance by means of the cells.

Abstract: The present invention relates to a cell culturing method and kit. More specifically, it relates to a cell culturing method and kit using a support that is exposed to the air. It further relates to a method of culturing cells by allowing them to migrate onto a porous polyimide film.

Abstract: The invention relates to a long term cell culturing method and a cell culturing apparatus and kit that employ a porous polyimide film. The invention further relates to a cell cryopreservation method and kit employing the porous polyimide film.

Abstract: The present invention provides: a method for producing a mixed sulfonic acid anhydride of the general formula (1) by reacting a sulfonic acid compound of the general formula (2) with a perfluoroalkyl sulfonic acid anhydride or a perfluoroalkyl sulfonic acid halide; and a method for producing a sulfonamide compound of the general formula (4) obtained by reacting an amine compound of the general formula (3) with a mixed sulfonic acid anhydride of the general formula (1).

Abstract: The present invention relates to a method for producing N-substituted sulfonamide compounds including a step of reacting a sulfonamide compound of general formula (1) with a halogenated organic compound of general formula (2) in the presence of cesium carbonate or potassium carbonate in an organic solvent to produce an N-substituted sulfonamide compound of general formula (3).

Abstract: A vibrational frequency adjustment device comprises, as a vibrational frequency adjustment means (22): a first conversion means (40) which is provided with an input-side rotating member (41), an output-side rotating member (42), and a one-way clutch (44) for transmitting only the rotational motion in one direction of the input-side rotating member (41) to the output-side rotating member (42) and which, by causing the input-side rotating member (41) to pivot in a reciprocating manner by a set angle by means of the reciprocating linear motion of an output shaft (10), transmits only the forward motion or the reverse motion of the input-side rotating member (41) to the output-side rotating member (42) through the one-way clutch (44) to thereby rotate the output-side rotating member (42) by a given angle; and a second conversion means (50) which converts the rotational motion of the output-side rotating member (42) into the reciprocating linear motion of a second shaft member (43).

Abstract: Provided is an oral cleaning device capable of ensuring a sufficient ejection pressure for a cleaning liquid while employing a small and low-cost electric air pump with a low output. An oral cleaning device is provided with an air-tightly closable cleaning liquid tank 2 which stores a cleaning liquid, a cleaning liquid supply passage 24 which has an ejection port 4a for ejecting the cleaning liquid into the oral cavity on one end and an introduction port 23a open inside the bottom part of the cleaning liquid tank 2 on the other end, and an electric air pump 44 which supplies air into the cleaning liquid tank 2 to pressurize the inside of the cleaning liquid tank 2. The cleaning liquid inside the cleaning liquid tank 2 is supplied to the ejection port 4a through the cleaning liquid supply passage 24 by air pressure inside the cleaning liquid tank 2.

Abstract: A method for producing prasugrel hydrochloride with a reduced content of 2-acetoxy-5-[5-chloro-1-(2-fluorophenyl)-2-oxopentyl]-4,5,6,7-tetrahydrothieno[3,2-6]pyridine by carrying out the following steps: wherein R represents a protecting group for a hydroxyl group.

Abstract: The present invention relates to a benzazepinone compound represented by the following formula (I): wherein R1 represents a C1-C6 alkyl group or halogeno C1-C6 alkyl group, R2 represents a carboxyl group which may be protected, and Y represents a group represented by the formula (II): wherein Z represents CH or a nitrogen atom, or a pharmaceutically acceptable salt thereof.

Abstract: A door opening and closing device for a vehicle that can remove an object attached to operation surface of a door handle with a simpler structure is provided. The device includes a door handle. The door handle includes a grip and a deflective portion. The grip protrudes outward and defines a space between the outer surface of the door outer panel and the grip to allow gripping by a user. The deflective portion is located at an end of the grip and extends from the outer surface of the grip along the outer surface of the door outer panel in a direction crossing front and rear directions of the vehicle to direct air flow flowing along the outer surface of the door outer panel to flow through at least the space of the grip to the operation surface.

Abstract: A vibrational frequency adjustment device comprises, as a vibrational frequency adjustment means (22): a first conversion means (40) which is provided with an input-side rotating member (41), an output-side rotating member (42), and a one-way clutch (44) for transmitting only the rotational motion in one direction of the input-side rotating member (41) to the output-side rotating member (42) and which, by causing the input-side rotating member (41) to pivot in a reciprocating manner by a set angle by means of the reciprocating linear motion of an output shaft (10), transmits only the forward motion or the reverse motion of the input-side rotating member (41) to the output-side rotating member (42) through the one-way clutch (44) to thereby rotate the output-side rotating member (42) by a given angle; and a second conversion means (50) which converts the rotational motion of the output-side rotating member (42) into the reciprocating linear motion of a second shaft member (43).