Abstract: It was found that the compound having a binding activity to the cannabinoid type 2 receptor represented by the formula (I): wherein R1 is a group represented by the formula: —Y1—Y2—Y3—Ra wherein Y1 is single bond or the like; Y2 is —C(?O)—NH— or the like; Y3 is optionally substituted aryl or the like; R2 is hydrogen or the like; R3 is alkyl or the like; R4 is alkyl or the like; R5 is optionally substituted alkyl or the like; or R3 and R4 taken together with the adjacent atom form cyclic group or the like.

Abstract: [Problems to be Solved] To provide a novel compound having antiviral activity, especially inhibitory activity against HIV integrase, a pharmaceutical composition, especially anti-HIV drug, containing the same.

Abstract: As the protocol used to transmit the MIDI message, TCP and UDP used widely as the transmission protocol are employed. A player terminal on the transmitter side classifies the transmitted MIDI message into the system exclusive message that should never be lost absolutely and other MIDI message. The player terminal on the transmitter side transmits the system exclusive message by using TCP with high reliability and transmits other MIDI message by using UDP with low reliability.

Abstract: Operational states of one or more operators employed in a vehicle are detected to generate operational information corresponding to the detected operational states. Also, one or more traveling states of the vehicle are detected to generate traveling information corresponding to the detected traveling states. There is provided a table storing correspondency between various operational and traveling information and various sound control information, and sound control information corresponding to generated operational or traveling information is obtained with reference to the table. Sound signal is generated on the basis of the obtained sound control information to auditorily inform a user of the vehicle of the operational or traveling state of the vehicle. Contents of the table may be changed as desired by the user. There may be provided a plurality of tables so that the user can select any one of the tables.

Abstract: A music session support method which enables each of players in a music session which is performed via a network to immediately recognize whether or not the other players are in the state of being able to participate in the session. A session support apparatus 10 transmits sets of status information indicative of whether or not each of players is in a state of being able to participate in a session, and player identification information which identifies the players, to each of session terminals 20. Each of the session terminals 20 which have received the sets of status information and player identification information causes a touch display 24 thereof to display the status information for each of the players.

Abstract: There are provided a download system and a download control method for portable players, which enable a user to download music data to the portable player by a simple operation, and a storage medium that stores a program for executing the download control method. The portable player includes a storage medium that stores music data having type data. A download device downloads previously stored music data to the storage medium of the portable player. A center station transmits music data having type data to the download device. In the download device, the type data of the music data stored in the storage medium is read in as known type data when the portable player is placed on a table. Type data input by a user is read in as desired type data. The type data of the music data transmitted from the center station is read in as new type data.

Abstract: In response to a readout instruction, tone reproducing digital data are read out which include information indicative of tone generating events and time lengths. Then, degrading processing is performed to change the information indicative of tone generating events and time lengths, included in the read-out tone reproducing digital data, in accordance with payment of a necessary charge for the digital data, and then the changed tone reproducing digital data are output. By thus performing the degrading processing on the read-out tone reproducing digital data in accordance with the payment of the necessary charge when the digital data are to be transferred or reproduced, there can be achieved an advantageous effect of reliably preventing unauthorized use of the digital data.

Abstract: It was found that the compound having a binding activity to the cannabinoid type 2 receptor represented by the formula (I): wherein R1 is a group represented by the formula: —Y1—Y2—Y3—Ra wherein Y1 is single bond or the like; Y2 is —C(?O)—NH— or the like; Y3 is optionally substituted aryl or the like; R2 is hydrogen or the like; R3 is alkyl or the like; R4 is alkyl or the like; R5 is optionally substituted alkyl or the like; or R3 and R4 taken together with the adjacent atom form cyclic group or the like.

Abstract: It was found that the compound having a binding activity to the cannabinoid type 2 receptor represented by the formula (I): ? wherein R1 is a group represented by the formula: —Y1—Y2—Y3—Ra wherein Y1 is single bond or the like; Y2 is —C(?O)—NH— or the like; Y3 is optionally substituted aryl or the like; R2 is hydrogen or the like; R3 is alkyl or the like; R4 is alkyl or the like; R5 is optionally substituted alkyl or the like; or R3 and R4 taken together with the adjacent atom form cyclic group or the like.

Abstract: A sensing encoder fitted to a jog dial senses a rotation direction and a rotation amount of a dial and supplies the sensed result to a controller as operation information. A pointer moving unit, when receives the operation information, decides a position of the pointer based on the operation information and sends a moving instruction to a display device. At the same time, the pointer moving unit reads a value of the data pointed by the moved pointer from a hard disk, and then supplies this value to a vibration controlling unit. The vibration controlling unit controls a vibration generated by a vibration generating actuator in response to the value of the data that are received from the pointer moving unit.

Abstract: As the protocol used to transmit the MIDI message, TCP and UDP used widely as the transmission protocol are employed. A player terminal on the transmitter side classifies the transmitted MIDI message into the system exclusive message that should never be lost absolutely and other MIDI message. The player terminal on the transmitter side transmits the system exclusive message by using TCP with high reliability and transmits other MIDI message by using UDP with low reliability.

Abstract: A music session support method which enables each of players in a music session which is performed via a network to immediately recognize whether or not the other players are in the state of being able to participate in the session. A session support apparatus 10 transmits sets of status information indicative of whether or not each of players is in a state of being able to participate in a session, and player identification information which identifies the players, to each of session terminals 20. Each of the session terminals 20 which have received the sets of status information and player identification information causes a touch display 24 thereof to display the status information for each of the players.

Abstract: In response to a readout instruction, tone reproducing digital data are read out which include information indicative of tone generating events and time lengths. Then, degrading processing is performed to change the information indicative of tone generating events and time lengths, included in the read-out tone reproducing digital data, in accordance with payment of a necessary charge for the digital data, and then the changed tone reproducing digital data are output. By thus performing the degrading processing on the read-out tone reproducing digital data in accordance with the payment of the necessary charge when the digital data are to be transferred or reproduced, there can be achieved an advantageous effect of reliably preventing unauthorized use of the digital data.

Abstract: The present invention provides an integrase inhibitor. The inventors have have found the following compound of formula (I) possessing an integrase inhibitory activity.

Abstract: It was found that the compound having a binding activity to the cannabinoid type 2 receptor represented by the formula (I): 1

Abstract: Operational states of one or more operators employed in a vehicle are detected to generate operational information corresponding to the detected operational states. Also, one or more traveling states of the vehicle are detected to generate traveling information corresponding to the detected traveling states. There is provided a table storing correspondency between various operational and traveling information and various sound control information, and sound control information corresponding to generated operational or traveling information is obtained with reference to the table. Sound signal is generated on the basis of the obtained sound control information to auditorily inform a user of the vehicle of the operational or traveling state of the vehicle. Contents of the table may be changed as desired by the user. There may be provided a plurality of tables so that the user can select any one of the tables.

Abstract: A peptide derivation of the formula (I) or its pharmaceutically acceptable salt or hydrate thereof is disclosed. These compounds have superior ability over thyroid stimulating hormone (TRH) and its derivatives to activate the central nervous system, such as, for example, sustained acetylcholine releasing action, anti-reserpine action and locomotor increment.

Abstract: The invention relates to novel uracil derivatives having excellent inhibiting effects on human derived thymidine phosphorylates and anti-tumor activity. The pharmaceutical compositions, anti-tumor potentiators and antitumor agents containing such novel compounds, and a process for their preparation and use are described.

Abstract: The invention relates to novel uracil derivatives having excellent inhibiting effects of human derived thymidine phosphorylase and anti-tumor activity. The pharmaceutical compositions, anti-tumor potentiators, antitumor agents containing such novel compounds, and a process for their preparation and use is described.

Abstract: The invention relates an epoxysuccinamide derivative represented by a formula (I): ##STR1## wherein R.sup.1 represents a hydrogen atom, an alkyl or aminoalkyl group, R.sup.2 represents an aminoalkyl group which May be substituted, an aryl group which may be substituted, a heterocyclic group which may be substituted, an aralkyl group which may be substituted, or an alkyl group substituted by a heterocyclic ring which may be substituted, or R.sup.1 and R.sup.2 may form a nitrogen-containing heterocyclic ring, which may be substituted, together with the adjacent nitrogen atoms, and R.sup.3 and R.sup.4 are the same or different from each other and independently represent a hydrogen atom, or an alkyl or aralkyl group, or a salt thereof, a preparation process thereof, and a medicine comprising such a derivative or salt as an active ingredient.