Abstract: To provide a gene transfer carrier that specifically accumulates only at a disease site even with systemic administration, has a high protein expression rate, and disappears from the disease site accompanying a cure, and a method for the treatment of an ischemic disease using same. The above-mentioned object has been accomplished by providing a gene transfer carrier formed from an anaerobic bacterium that can grow specifically at the site of an ischemic disease and can express at least one type of protein that is useful for the diagnosis or treatment of an ischemic disease, a pharmaceutical composition containing the gene transfer carrier, and a treatment method for an ischemic disease utilizing same.

Abstract: A chemical conversion agent which is capable of providing, for example, an aluminum-based metal material with excellent corrosion resistance and moisture resistance, while also providing the aluminum-based metal material with excellent adhesion with a laminate film, excellent hydrofluoric acid resistance, and excellent alkali resistance. The chemical conversion agent has (1) a mass concentration of zirconium of 5-5,000 ppm by mass; (2) a mass concentration of titanium is 5-5,000 ppm by mass; (3) a mass concentration of vanadium is 10-1,000 ppm by mass; (4) a mass concentration of a metal stabilizer is 5-5,000 ppm by mass; and (5) the pH is 2-6.

Abstract: A surface treatment method for aluminum heat exchangers including (a) a step wherein a chemical conversion coating film is formed on the surface of an aluminum heat exchanger by subjecting the aluminum heat exchanger to chemical conversion using a chemical conversion agent; (b) a step wherein the aluminum heat exchanger, the surface of which has been provided with a chemical conversion coating film in step (a), is brought into contact with a hydrophilizing agent that contains a hydrophilic resin; and (c) a step wherein a hydrophilized coating film is formed on the surface of the aluminum heat exchanger by baking the aluminum heat exchanger, which has been subjected to a contact treatment in step (b). The chemical conversion agent used in step (a) contains zirconium and/or titanium in an amount of 5-5,000 ppm by mass in total, vanadium in an amount of 10-1,000 ppm by mass and a metal stabilizer in an amount of 5-5,000 ppm by mass. In addition, the chemical conversion agent used in step (a) has a pH of 2-6.

Abstract: A surface treatment method capable of imparting exceptional corrosion resistance and moisture resistance to an NB heat exchanger. The method includes subjecting an NB heat exchanger to a chemical conversion treatment to form a chemical conversion film on the surface thereof using a chemical conversion treatment agent that contains zirconium and/or titanium in a total amount of 5-5,000 ppm by weight, vanadium in an amount of 10-1,000 ppm by weight, and has a pH of 2-6; bringing the NB heat exchanger on whose surface the chemical conversion film is formed into contact with a hydrophilization agent containing a hydrophilic resin and a guanidine compound and/or a salt thereof; and baking the NB heat exchanger subjected to the contacting process, whereby a hydrophilic film is formed on the surface thereof.

Abstract: The invention relates to a jig for microneedle array placement that is provided with a main jig body with through holes through which the microneedles of the microneedle array will pass and a guiding part that guides the microneedle array to be incorporated into the main jig body and leads the microneedles into the through holes, and a microneedle array device using the jig for microneedle array placement. The invention prevents the deformation of the skin surface during puncture and allows penetration of the microneedles to the prescribed depth under the skin.

Abstract: [Object] To provide a gene transfer carrier that specifically accumulates only at a disease site even with systemic administration, has a high protein expression rate, and disappears from the disease site accompanying a cure, and a method for the treatment of an ischemic disease using same. [Solution means] The above-mentioned object has been accomplished by providing a gene transfer carrier formed from an anaerobic bacterium that can grow specifically at the site of an ischemic disease and can express at least one type of protein that is useful for the diagnosis or treatment of an ischemic disease, a pharmaceutical composition containing the gene transfer carrier, and a treatment method for an ischemic disease utilizing same.