Abstract: Disclosed are a cocaine esterase mutant and use thereof. The cocaine esterase mutant is obtained by mutating a wildtype cocaine esterase, an amino acid sequence of the wildtype cocaine esterase is shown as SEQ ID No.1, the cocaine esterase mutant is T172R/G173Q/L196C/I301C, or additionally added with V116K point mutation, or additionally added with A51 site mutation, and the A51 site mutation is L, Y, V, F or W. Catalytic efficiency of the cocaine esterase mutant screened on a cocaine toxic metabolite benzoylecgonine is greatly improved compared with that of a wildtype enzyme.

Abstract: The present invention relates to the field of pharmaceutical and chemical engineering, and specifically relates to a weakly acidic microenvironment-sensitive aptamer for tumors, a triptolide conjugate. The conjugate is formed by conjugation between the 14-position hydroxyl group of triptolide and the aptamer via an acetal ester linking bond, which is an acid-sensitive linking bond with a cleavage condition of (pH=3.5-6.5), which is much less pH-sensitive and is more likely to cleave under the tumor microenvironment. Based on the characteristics of the aptamer targeting the highly expressed proteins on the membrane surface of tumor cells, the conjugate delivered triptolide targeted to tumor cells and mediated endocytosis to reach the lysosome; based on the characteristics of the acidic environment of lysosomes, the acetal ester linking bond released intact triptolide in the lysosomal acidic environment, targeting and killing of tumor cells.

Abstract: A handover processing method, a terminal, and a storage medium are provided. The method includes the following. The terminal acquires at least one handover command, the at least one handover command including at least one of a first handover command, a second handover command, and a conditional handover command, where the first handover command is indicated through layer 1 or layer 2 signaling and the second handover command being indicated through layer 3 signaling. The terminal determines, according to the at least one handover command, a handover command to be preferentially executed. The terminal performs cell handover according to the handover command to be preferentially executed.

Abstract: Disclosed in the present application is a display device. The display device includes a display panel, a backplate, and a composite support layer; the backplate is disposed on one side of the display panel; the composite support layer is disposed on one side of the backplate away from the display panel, the composite support layer includes a rigid support sub-layer and a flexible support sub-layer which are sequentially laminated; wherein a material of the rigid support sub-layer comprises polymethyl methacrylate, and a material of the flexible support sub-layer comprises polycarbonate.

Abstract: A method for wireless communication, a terminal, and a storage medium are provided in implementations of the disclosure. The method includes: determining, by a terminal, at least one of an available relay or a suitable cell, when a radio link failure or a handover failure is detected by the terminal; and performing, by the terminal, a radio resource control (RRC) reestablishment or a handover procedure through the at least one of the available relay or the suitable cell to access a first cell, where the first cell includes a cell accessed by the available relay or the suitable cell.

Abstract: A method for uplink data transmission, a user equipment (UE), and a storage medium are provided. The method is performed by a UE. The method includes: indicating in small data transmission (SDT) associated information of data to-be-transmitted when the UE is in an inactive state and has the data to-be-transmitted.

Abstract: A configuration method and apparatus for Conditional Primary Secondary Cell Group Cell (PSCell) Change (CPC) in dual connectivity, a storage medium, a base station, and a terminal are provided. The method includes: for configuring the CPC for a User Equipment (UE), determining whether a configuration threshold has been received from a master base station, wherein the configuration threshold is a number threshold of CPCs configurable by a secondary base station; and determining a number of the CPCs configurable by the secondary base station based on the number threshold, in response to the configuration threshold having been received from the master base station, wherein the number of the CPCs configurable by the secondary base station is less than or equal to the configuration threshold.

Abstract: A method for receiving multicast service data is provided. The method includes the following. A terminal device transmits first indication information to a network device, where the first indication information indicates a target multicast service. The terminal device receives at least one downlink control information (DCI) transmitted by the network device, where the at least one DCI is used for scheduling the target multicast service. The terminal device restarts a bandwidth part (BWP) inactivity timer when the terminal device receives on a first BWP, according to the at least one DCI, data of the target multicast service transmitted by the network device.

Abstract: A method for data transmission of a multi-card UE is provided. The multi-card UE has at least a first subscriber identity module (SIM) card and a second SIM card, the first SIM card is in a connected status with a network. The method includes: determining a wireless operation demand of the second SIM card, and requesting a transmission time gap from the network according to the wireless operation demand, for enabling the second SIM card to execute a wireless operation in the transmission time gap. The method further includes generating a gap adjustment request according to the wireless operation executed by the second SIM card, and sending the gap adjustment request to the network, for enabling the network to adjust allocated transmission time gap according to the gap adjustment request.

Abstract: A data transmission method is provided by embodiments of the present disclosure. When a UE is in an idle state or an inactive state, if data which needs to be transmitted has been generated in the UE, the quantity of bits of the data to be transmitted in the UE is determined; then a target transmission mode corresponding to the quantity of bits is determined based on transmission configuration information; and the data to be transmitted is transmitted based on the target transmission mode; where the target transmission mode includes any one of the following modes: performing data transmission by the UE based on a random access procedure, performing data transmission by the UE based on a transmission resource pre-configured by a network device, or performing data transmission by the UE after transitioning to a connected state.

Abstract: A method including: determining whether the receiving terminal has received a second data packet when a first data packet in a plurality of data packets continuously sent by a sending terminal at an interval in a preset sending sequence is received, the second data packet comprises the data packet preceding the first data packet in the preset sending sequence; determining whether the second data packet is expired when the second data packet is not received; acquiring a consumption importance level of the second data packet when the second data packet is expired; and consuming the first data packet when the consumption importance level of the second data packet is a preset consumption importance level. Through the present disclosure, an application corresponding to the plurality of data packets is responded timely to avoid a delayed response to the applications. For example, the smoothness of the application is improved.

Abstract: The invention provides a method of and apparatus for controlling a ProSe service in a communication system. An eNB sends a first PLMN identifier, and carrier frequency information of another PLMN to indicate at least one carrier frequency at which a UE of the other PLMN can carry out the ProSe service, to a UE in a shared cell, and if the UE is in an idle state, then the UE reselects a cell or selects a PLMN; or if the UE is in a connected state, then the UE performs a handover procedure. If the handover procedure fails, then the UE releases an RRC connection to enter the idle states, or is DRX-configured and carries out the ProSe service in a DRX sleep time. With the solution of the invention, the UE can reselect or be handed over to the cell to carry out the ProSe service at the carrier frequency indicated by the carrier frequency information to thereby avoid the problem of an overload arising from too many ProSe services being carried out concurrently in the shared cell.

Abstract: A cell conditional change method, a user equipment and a computer-readable storage medium are provided. The method includes: based on determining that a candidate PSCell meets a PSCell change trigger condition, transmitting an RRC signaling to an MN, wherein a candidate PSCell or a target PSCell that meets the PSCell change trigger condition is indicated in the RRC signaling.

Abstract: Cell handover method and apparatus are provided. The method applied to a first base station includes: transmitting a handover request message, wherein the handover request message includes a capacity indication message of a pre-configuration parameter; receiving a handover request acknowledgement message, wherein the handover request acknowledgement message includes the pre-configuration parameter, and a capacity of the pre-configuration parameter is determined based on the capacity indication message; and transmitting a handover command based on the handover request acknowledgement message.

Abstract: A transmission control method and apparatus for downlink control information, and a storage medium, a base station and a terminal. The transmission control method comprises: receiving user equipment capability information sent by a user equipment, wherein the user equipment capability information comprises indication information regarding whether an enhanced CCE is supported; and according to the user equipment capability information, determining whether the enhanced CCE is to be used to schedule the user equipment, and when the enhanced CCE is used to schedule the user equipment, selecting the number of REGs contained in a single CCE from a first set, and when the enhanced CCE is not used to schedule the user equipment, selecting the number of REGs contained in a single CCE from a second set, wherein the first set is different from the second set. By means of the technical solution provided in the present invention, the utilization rate of resources can be improved.

Abstract: A method and apparatus for determining a groupcast feedback resource, a storage medium and a User Equipment (UE) are provided. The method is applied at a first Receiver (Rx) UE and includes: receiving sidelink control information and transmission data from a Transmitter (Tx) UE, wherein the Tx UE transmits the sidelink control information and the transmission data using a groupcast mode; determining a position of a first available feedback resource based on a position of the transmission data scheduled by the sidelink control information and a second preset mapping relationship; and determining the feedback resource for the first Rx UE based on an intra-group identifier of the first Rx UE and the position of the first available feedback resource.

Abstract: A channel quality reporting method and apparatus for direct links, a storage medium, and a user equipment are provided. The channel quality reporting method includes: receiving report indication information, wherein the report indication information indicates at least one direct link that needs to be reported or a report condition; determining at least one reported direct link at least based on the report indication information; and reporting channel quality of the at least one reported direct link or information of the at least one reported direct link.

Abstract: Provided are a method and a device for multi-carrier data transmission. The method includes: performing, by a first UE, data transmission between UEs via a first carrier; determining, based on a status of a second UE, a second carrier for performing multi-carrier data transmission; and performing data transmission between UEs via the first carrier and the second carrier. The device includes: a second carrier determination module, configured to determine, based on a status of a second UE, a second carrier for performing multi-carrier data transmission in response to data transmission being performed with the second UE via a first carrier; and a transmission module configured to perform data transmission between UEs via the first carrier and the second carrier.

Abstract: Provided are a transmitting method and a transmitting device for uplink control information, a storage medium, and a user equipment. The transmitting method includes: receiving PUCCH resource assignment information sent from a network to determine a PUCCH format and assigned resource blocks; and resource mapping the uplink control information at least based on all frequency domain resources of the assigned resource blocks, if the determined PUCCH format is one that requires more than one physical resource block for resource transmission and a number of the assigned resource blocks is larger than that required for transmitting the uplink control information. With the technical solution provided in the present disclosure, when the uplink control information is transmitted in unlicensed spectrums in a PUCCH format requiring more than one physical resource block for resource transmission, the occupation ratio of the uplink power in unlicensed spectrums can be significantly improved.

Abstract: Method and apparatus for reporting an RLC layer status, storage medium and user equipment are provided. The method includes: determining whether an RLC status report needs to be transmitted in an acknowledgment mode; based on that the RLC status report needs to be transmitted, determining at least one unacknowledged sequence number length, wherein the unacknowledged sequence number length is selected from a set of unacknowledged sequence number length including elements pre-defined by a transmitter and a receiver; generating the RLC status report based on the at least one unacknowledged sequence number length and a sequence number of a start RLC data packet of RLC data packets consecutively unreceived, wherein the RLC status report is in a preset format of RLC status report, and records the total number of the RLC data packets consecutively unreceived and the sequence number of the start RLC data packet; and transmitting the RLC status report.