Abstract: This disclosure relates generally to cannabinoid derivatives having the structural formula (I), pharmaceutical compositions comprising them, and methods of using the cannabinoid derivatives. In some embodiments, R1 is —CH2CH?C(CH3)2, R2 is methyl, R3 is CsHn, R4 is —C(O)N(R4a)(R4b), R5 is H, R6 is OH, and R7 is H. Compounds of the present disclosure were tested in agonist and antagonist mode for both the CB1 and CB2 receptors. The tested compounds were generally found to exhibit activity in antagonist mode at the CB1 and CB2 receptor.

Abstract: A liquid formulation of a long-acting conjugate of GLP-2 and a method for preparing the liquid formulation are disclosed. The liquid formulation contains 18 nmol/mL to 18,630 nmol/mL of a long-acting conjugate, a stabilizer, and a buffering agent in an amount for maintaining the pH of the liquid formulation in the range of 4.5 to 6.5.

Abstract: The present disclosure relates to a method for preparing a restructured hydrogel, including forming a hydrogel containing a first polymer, unidirectionally shrinking and dehydrating the hydrogel, and additionally cross-linking and rehydrating the dehydrated hydrogel.

Abstract: Disclosed are a positron emission tomography system and an image reconstructing method using the same and the positron emission tomography system includes: a collection unit collecting a positron emission tomography sinogram (PET sinogram); an image generation unit applying the positron emission tomography sinogram to an MLAA with TOF and generating a first emission image and a first attenuation image and a NAC image reconstructed without attenuation correction; and a control unit selecting at least one of the first emission image, the first attenuation image and the NAC image generated by the image generation unit as an input image and generating and providing a final attenuation image by applying the input image to the learned deep learning algorithm.

Abstract: According to an embodiment, a method of simulating a three-dimensional (3D) padded garment includes generating a second pattern corresponding to a first pattern that is a two-dimensional (2D) pattern, generating an intermediate pattern positioned between the first pattern and the second pattern to which a pressure value is applied, wherein the intermediate pattern comprises a collision value, and generating the 3D padded garment based on at least one of the first pattern, the second pattern, and the intermediate pattern.

Abstract: In one example, a semiconductor structure comprises a redistribution structure comprising a conductive structure, a cavity substrate on a top side of the redistribution structure and having a cavity and a pillar contacting the redistribution structure, an electronic component on the top surface of the redistribution structure and in the cavity, wherein the electronic component is electrically coupled with the conductive structure, and an encapsulant in the cavity and on the top side of the redistribution structure, contacting a lateral side of the electronic component, a lateral side of the cavity, and a lateral side of the pillar. Other examples and related methods are also disclosed herein.

Abstract: The present invention relates to changes in interleukin-2 alpha receptors and interleukin-2 analogs with increased binding affinity for interleukin-2 beta receptors.

Abstract: The hollow shaft motor according to the present invention comprises: a housing 11 having a cylindrical shape; an upper cover 12 coupled to an upper portion of the housing 11; a lower cover 15 coupled to a lower portion of the housing 11; a stator assembly 20 located in the housing 11; and a rotor assembly 30 located in the stator assembly 20 to rotate, comprising a hollow shaft 31, a rotor core 32 coupled to the hollow shaft 31, and a plurality of magnets 33 arranged on an outer circumferential surface of the rotor core 32 at a certain interval, wherein the hollow shaft 31 is manufactured with a plastic resin by an insert injection molding in the state where the rotor core 32 and the magnet 33 are located in an insert injection mold.

Abstract: The method for decellularization of kidney tissue according to the present invention, the decellularized material produced through the method, and a bioink comprising the decellularized material have the effect of maximizing the effect of kidney treatment by maximizing the content of components specialized for kidney treatment such as the collecting duct and renal tubule of the kidney.

Abstract: This invention relates to a method for preparing superabsorbent polymer. More specifically, this invention relates to a method for preparing superabsorbent polymer that realizes excellent drying efficiency, and thus, effectively inhibits warping of resin.

Abstract: An attachable/detachable toecap coupled to the front of the work shoes is disclosed. The attachable/detachable toecap coupled to the front of the work shoe comprises a top plate formed to cover toes and a portion of top of a foot; a side plate formed to extend downwards from the side of the top plate and to surround the top plate; a bottom plate formed to be under the side plate and to cover the bottom of the front of the work shoe; and an anti-separation means for preventing separation of the toecap from the work shoes, wherein the anti-separation means further comprises coupling blocks protruding from the bottom of the work shoe and coupling grooves formed to have vertical perforations at the position corresponding to the coupling blocks, so that the coupling blocks are snap-fitted to prevent the separation of the toecap from the work shoe.

Abstract: A semiconductor device includes a chip body; a circuit layer over the chip body; an upper insulating layer over the circuit layer; a chip metal layer over the upper insulating layer, the chip metal layer including a pad portion; a passivation layer over the chip metal layer; a lower redistribution insulating layer over the passivation layer, the pad portion of the chip metal layer left exposed by the passivation layer and the lower redistribution insulating layer; a redistribution bonding interconnection over the lower redistribution insulating layer; and an upper redistribution insulating layer over the lower redistribution insulating layer.

Abstract: An apparatus that detects a rotor input is provided. The apparatus includes a rotor comprising at least a portion which is configured to rotate around an axis of rotation; a reactance element disposed in the rotor, a sensing medium member disposed in the rotor, and a motion conversion member configured to move in the rotor based on a rotation of the portion of the rotor, and configured to move together with the sensing medium member to change a reactance of the reactance element according to the rotation of the portion of the rotor.

Abstract: An electronic device includes a narrowband internet of things (NB-IoT) circuit; a shared central processor to control the narrowband internet of things circuit; a shared memory to store data or code from the shared central processor; and a communicator controlled by the shared central processor. The communicator stores the data or the code in the shared memory.

Abstract: A polishing pad for chemical mechanical polishing includes a polymer matrix and a temperature sensitive agent dispersed in the polymer matrix and constituting 1 to 40% by volume of the polishing pad, wherein the temperature sensitive agent includes a two-dimensional (2D) sheet material having a thermal conductivity of 1 W/(m·K) or more.

Abstract: Discussed is a light-emitting device including a first light-emitting layer so that a dopant having a hole trapping property is adjacent to a hole transport layer, and a second light-emitting layer that comes into contact with the first light-emitting layer to induce main light emission, thereby widening an emission zone and improving the efficiency and lifespan of the light-emitting layer. Also discussed is a light-emitting display including the light-emitting device. The first and second blue light-emitting layers can include a same host BH and different first and second blue dopants, respectively, and the first blue dopant can have a higher highest occupied molecular orbital (HOMO) energy level than a HOMO energy level of the hole transport layer.

Abstract: A method and apparatus for generating a fixed point neural network are provided. The method includes selecting at least one layer of a neural network as an object layer, wherein the neural network includes a plurality of layers, each of the plurality of layers corresponding to a respective one of plurality of quantization parameters; forming a candidate parameter set including candidate parameter values with respect to a quantization parameter of the plurality of quantization parameters corresponding to the object layer; determining an update parameter value from among the candidate parameter values based on levels of network performance of the neural network, wherein each of the levels of network performance correspond to a respective one of the candidate parameter values; and updating the quantization parameter with respect to the object layer based on the update parameter value.

Abstract: A coil electronic component includes an insulating substrate, a coil portion disposed on at least one surface of the insulating substrate, a body in which the insulating substrate and the coil portion are embedded, a lead-out portion connected to the coil portion and exposed from a surface of the body, and a connection portion including a plurality of connecting conductors each having a bent portion to increase lengths of the plurality of connecting conductors embedded in the body, the plurality of connecting conductors being spaced apart from each other, the connection portion connecting an end of the coil portion to the lead-out portion to each other.

Abstract: An organic light emitting diode can include a reflective electrode, a transparent electrode facing the reflective electrode, and a first emitting part including a first blue emitting material layer and positioned between the reflective electrode and the transparent electrode, a second emitting part including a second blue emitting material layer and positioned between the first emitting part and the transparent electrode, and a charge generation layer positioned between the first and second emitting parts. The first blue emitting material layer includes a fluorescent compound, and the second blue emitting material layer includes a fluorescent compound and a phosphorescent compound. A difference between a second emission peak intensity of the fluorescent compound in the second blue emitting material layer and a second emission peak intensity of the fluorescent compound in the first blue emitting material layer is 0.1 or less.

Abstract: The present disclosure is directed to compounds of formula (I): wherein R1, R2, R3, R3a, R4, Y, and X are as described herein, as stereoisomers, enantiomers, or tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates, or prodrugs thereof, and pharmaceutical compositions comprising the compounds of formula (I), as described herein, which are useful as voltage-gated sodium channel modulators and are therefore are useful in treating seizure disorders such as epilepsy.