Abstract: A method for survival prediction in cancer patients is provided. In one embodiment, the survival prediction is determined by the presence or absence of KRAS gene region deletion and/or loss of Chromosome 12 (Ch. 12) in cancer tumor tissue. In another embodiment, the presence or absence of KRAS gene region deletion and/or loss of Ch. 12 in cancer tumor tissue is used to predict survival in non-small-cell lung cancer (NSCLC) patients.

Abstract: Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme. These inhibitors may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases.

Abstract: Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.

Abstract: A detection-alarm mechanism is provided. The detection-alarm mechanism for a tire includes a sensor, an electronic processing unit, a post-processing unit and a display unit. The sensor includes a substrate disposed in the tire and at least one photoelectronic element fixed to the substrate. If the tire is cracked, light passes through the cracks and reaches the photoelectronic elements to generate signals. The electronic processing unit receives signals from the photoelectronic elements to generate wear information. The post-processing unit is disposed in a vehicle on which the tire is installed and receives wear information from the electronic processing unit. The display unit is disposed in the vehicle for presenting the wear information.

Abstract: Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme. These inhibitors may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases.

Abstract: A detection-alarm mechanism is provided. The detection-alarm mechanism for a tire includes a sensor, an electronic processing unit, a post-processing unit and a display unit. The sensor includes a substrate disposed in the tire and at least one photoelectronic element fixed to the substrate. If the tire is cracked, light passes through the cracks and reaches the photoelectronic elements to generate signals. The electronic processing unit receives signals from the photoelectronic elements to generate wear information. The post-processing unit is disposed in a vehicle on which the tire is installed and receives wear information from the electronic processing unit. The display unit is disposed in the vehicle for presenting the wear information.

Abstract: Disclosed are methods of using blastomere-like stem cells to treat a number of immunodeficiency disorders.

Abstract: Disclosed are novel stem cells of non-embryonic origins and the uses thereof.

Abstract: The invention relates to an orthogonal frequency division multiplexing system with PN-sequence. In the synchronization of the invention, both timing offset and frequency offset are estimated and compensated by utilizing a time and frequency synchronization device. In addition, the PN-sequence with the cyclic prefix is added to the OFDM symbol before transmitting. The time and frequency synchronization device of the invention comprises two synchronization circuits from the cyclic prefix and PN-sequence when calculating the timing offset and frequency offset of receiving signal. As a result, the OFDM system of the invention not only has better performance in fading channel, but also has the better bandwidth utilization without extra bandwidth for transmitting the PN-sequence.

Abstract: The present invention provides a communication method of a community system, comprising the steps of: receiving a message from a member of a first environment by an apparatus; according to a community descriptive element of the message, examining whether the member of the first environment belongs to a first personal social network corresponding to the message; and if affirmative, providing a service according to the acquirement of the message.

Abstract: A wireless communication system using channel access based on a contention approach and method thereof is disclosed, which allocates plural sets of time slots in a predetermined contention interval, wherein each set of time slots further includes plural adjacent overlapped time slots. A channel requester transmits a contention message to a channel allocator at a time slot based on an interleaved method after the channel requester completes count down of a predetermined time, so that the positions of the headers of the contention messages in the adjacent time slots of each set of time slot are different. Thus, if the contention message transmitted by the channel requester collides with the contention message of the adjacent time slot, the channel allocator can parse the headers of the collided contention messages and respectively allocate plural special channel times for communicating with the channel requesters.

Abstract: Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme. These inhibitors may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases.

Abstract: The present invention relates to an extensible protocol processing system. The system of the invention is mounted between a host and a network, and is utilized to offload partial network protocol packets of the host. The protocol processing system comprises a microprocessor, a host interface device, a medium access controller, a message interface controller, a receiving device and a transmitting device. The system of the invention can provides better efficiency of the host for processing the offloaded partial network protocol packets. Besides, the function of the system of the invention can be extended by increasing the message and modifying the software or the firmware. Therefore, the system of the invention can be utilized to various applications, and has the easily extensible effects.

Abstract: A method for social relationship oriented service processing, which comprises steps of: providing relationship data, searching for at least one first level social member from a first level social network according to the relationship data, forwarding a list of the first level social members to a server, and searching by the server for at least one second level social member from a second level social network according to the list and the relationship data.

Abstract: A turning indication system for a two-wheeled vehicle includes a first unit connected to a two-wheeled vehicle and emits signals when the vehicle turns. The first unit includes a mode switch unit from which the rider can set different operation modes. A second unit is connected to a helmet and includes a first light unit, a second light unit and a power source which is electrically connected to the first and second light units. The second unit receives the signals from the first unit and activating the first light unit and/or the second light unit according to a command of the mode switch unit. The first light unit includes at least one light emitting diode and the second light unit displays in a form of a pattern or character. The system provides an obvious signal to the riders following.

Abstract: A protocol processing engine system, which is arranged between a host side and a media access control (MAC) layer to thus speed up data transmission. The system includes a host interface, a network media access control (MAC) interface, a receiving subsystem and a transmitting subsystem. The system uses the host interface to interface with the host side and the network MAC interface to interface with the network MAC layer. The receiving subsystem classifies a connection received from the network MAC layer into a priority connection, fast connection or slow connection based on a pre-stored information, and activates its respective hardware circuit based on the connection classified in order to speed up data transmission of the connection. The transmitting subsystem transmits a connection received from the host interface to the network MAC interface.

Abstract: Disclosed are sustained release compositions for vaginal or transdermal administration that contain a progesterone receptor modulator such as CDB-2914 (also referred to as VA-2914), and methods of using them for long term contraception or therapeutic purposes. Also disclosed are methods for making the compositions.

Abstract: A detection-alarm mechanism is provided. The detection-alarm mechanism for a tire includes a sensor, an electronic processing unit, a post-processing unit and a display unit. The sensor includes a substrate disposed in the tire and at least one photoelectronic element fixed to the substrate. If the tire is cracked, light passes through the cracks and reaches the photoelectronic elements to generate signals. The electronic processing unit receives signals from the photoelectronic elements to generate wear information. The post-processing unit is disposed in a vehicle on which the tire is installed and receives wear information from the electronic processing unit. The display unit is disposed in the vehicle for presenting the wear information.

Abstract: A short-range inter-vehicle communication and warning apparatus comprises a forward radar and a backward radar. The apparatus uses the radars to generate Frequency Modulation/Continuous Wave (FMCW) signals, uses amplitude shift keying for data modulation and arranges a special packet format, to realize such a low cost and fast response device of collision avoidance for vehicles. The invention has the dual capabilities of detecting and communicating simultaneously. It can also measure the relative speed of a preceding/rear vehicles and the relative inter-vehicle distance. The invention also exchanges the real-time traffic information with the preceding/rear vehicles at the same time. It is applicable to a one-to-one or one-to-many inter-vehicle channel model.

Abstract: The expression of HMGA2 is often associated with neoplastic transformation. The present disclosure establishes a correlation between increased HMGA2 expression and enhanced chemosensitivity towards DNA-damaging therapeutic agents such as doxorubicin, cisplatin, and X-ray irradiation.