Patents by Inventor Yunbing Wang

Yunbing Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Improving fracture toughness of medical devices with a stereocomplex nucleating agent
    Patent number: 8337739
    Abstract: Methods of fabricating a polymeric implantable device from a PLLA/PDLA blend such as a stent with improved fracture toughness are disclosed. The blend is melt processed to allow formation of stereocomplex crystallites, which are nucleation sites for crystal growth. A polymer construct is formed from the melt processed blend and device is formed from the polymer construct. The stereocomplex crystallites result in an in increase in nucleation density and reduced crystal size, which increases fracture toughness of the formed device.
    Type: Grant
    Filed: August 12, 2008
    Date of Patent: December 25, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, James Oberhauser
  • Implantable medical devices comprising poly[l-lactide-co-(3,6-dialkyl-1,4-dioxane-2,5-dione)]
    Patent number: 8323678
    Abstract: This invention is directed to implantable medical device comprising a polymeric composition comprising poly[L-lactide-co-(3,6-dialkyl-1,4-dioxane-2,5-dione)], alone or as a blend with one or more polymers selected from the group consisting of poly(L-lactide) and poly(3,6-dialkyl-1,4-dioxane-2,5-dione).
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: December 4, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Xiao Ma, Lothar Kleiner, Thierry Glauser
  • Method and System for Manufacturing a Polymer Endoprosthesis by Injection Molding and Blow Molding
    Publication number: 20120299226
    Abstract: A polymer endoprosthesis is fabricated by a combination of injection molding and blow molding which form a tubular substrate of polymer material, followed by laser cutting, crimping and sterilization. After the injection and blow molding processes, a subtractive process is performed on the tubular substrate to transform it into a stent having a network of stent struts. The tubular substrate can be made in an injection mold and blow mold which are attached to each other. The transition from injection molding and blow molding can be performed while the injection molded substrate remains at a temperature at or above Tg of the polymer material.
    Type: Application
    Filed: May 24, 2011
    Publication date: November 29, 2012
    Applicant: Abbott Cardiovascular Systems Inc,
    Inventors: Yunbing Wang, James Oberhauser
  • Implantable Medical Devices Fabricated From Polymers With Radiopaque Groups
    Publication number: 20120303114
    Abstract: Implantable medical devices comprising radiopaque star-block copolymers.
    Type: Application
    Filed: July 30, 2012
    Publication date: November 29, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, David C. Gale, Vincent J. Gueriguian
  • Methods of Stabilizing Molecular Weight of Polymer Stents After Sterilization
    Publication number: 20120285123
    Abstract: Methods of stabilizing the molecular weight of polymer stents scaffolds after E-beam sterilization are disclosed. The molecular weight of the polymer of the irradiated scaffolds is stabilized through exposure to gas containing oxygen.
    Type: Application
    Filed: May 9, 2011
    Publication date: November 15, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Derek Mortisen, Xiao Ma, Fuh-Wei Tang, Byron Lambert
  • Method of Increasing Stent Retention of Bioabsorbable Scaffolding with a Sheath
    Publication number: 20120290063
    Abstract: A medical device includes a polymer stent crimped to a catheter having an expansion balloon. The stent is crimped to the balloon by a process that includes heating the stent to a temperature below the polymer's glass transition temperature to improve stent retention without adversely affecting the mechanical characteristics of the stent when later deployed to support a body lumen. A variable diameter sheath with a central portion that prevents expansion of the stent when the balloon is pressurized and larger diameter ends is disposed over the crimped stent-balloon assembly. The balloon is pressurized and the larger diameter ends of the sheath allow the balloon beyond the ends of the stent to expand. The balloon is then depressurized.
    Type: Application
    Filed: May 9, 2011
    Publication date: November 15, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Xiao Ma, Rommel C. Lumauig
  • Bioabsorbable Scaffold With Particles Providing Delayed Acceleration of Degradation
    Publication number: 20120290071
    Abstract: Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. A bioabsorbable scaffold having a plurality of particles incorporated into the scaffolding that accelerate the absorption of the scaffolding after an induction time during degradation is disclosed.
    Type: Application
    Filed: May 10, 2011
    Publication date: November 15, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, James Oberhauser
  • Methods for Crimping a Polymeric Scaffold to a Delivery Balloon and Achieving Stable Mechanical Properties in the Scaffold After Crimping
    Publication number: 20120285609
    Abstract: A medical device-includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes inflating the delivery balloon during a diameter reduction to improve scaffold retention. A crimping temperature is maintained at about the onset of glass transition of the polymer material to facilitate more rapid stabilization of mechanical properties in the scaffold following crimping.
    Type: Application
    Filed: May 13, 2011
    Publication date: November 15, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • Control Of Degradation Profile Of Bioabsorbable Poly(L-Lactide) Scaffold
    Publication number: 20120290070
    Abstract: Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. Disclosed methods include controlling features of the degradation profile including the time to loss of radial strength and the degradation time of the stent.
    Type: Application
    Filed: May 10, 2011
    Publication date: November 15, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Xiao Ma
  • BIOABSORBABLE SCAFFOLDS MADE FROM COMPOSITES
    Publication number: 20120290073
    Abstract: Bioabsorbable scaffolds made at least in part of a poly(L-lactide)-based composite are disclosed. The composite includes poly(4-hydroxybutyrate) or poly(L-lactide)-b-polycaprolactone block copolymer, which increases the fracture toughness or fracture resistance of the scaffold. The composite can further include bioceramic particles, L-lactide monomer, or both dispersed throughout the composite. The bioceramic particles improve the radial strength and stiffness of the scaffold. The L-lactide monomer is used to control the absorption rate of the scaffold.
    Type: Application
    Filed: May 13, 2011
    Publication date: November 15, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • Method of making Polymer-bioceramic composite implantable medical devices
    Patent number: 8309114
    Abstract: Methods and devices relating to polymer-bioceramic composite implantable medical devices are disclosed.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: November 13, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: David C. Gale, Yunbing Wang, Syed Faiyaz Ahmed Hossainy, Bin Huang, Garth L. Wilkes, Vincent J. Gueriguian
  • Polymer tube expansion apparatus to maximize fracture toughness
    Patent number: 8303296
    Abstract: Methods of and systems for fabricating a polymeric stent with improved fracture toughness including radial expansion of a polymer tube along its entire length at the same time and fabricating a stent from the expanded tube are disclosed herein.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: November 6, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Lothar W. Kleiner, James P. Oberhauser, Thierry Glauser, David K. Wrolstad, Yunbing Wang
  • STENT WITH NUCLEATING AGENT
    Publication number: 20120277358
    Abstract: The use of nucleating agents to manufacture polymeric stents is disclosed. The resulting stents may have increased crystallinity, decreased crystal size, increased mechanical properties, and faster degradation times.
    Type: Application
    Filed: July 12, 2012
    Publication date: November 1, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices
    Patent number: 8293260
    Abstract: Implantable medical devices with elastomeric copolymer coatings are disclosed.
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: October 23, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • STENTS INCLUDING POLY(L-LACTIDE) FORMULATIONS THAT MINIMIZE MOLECULAR WEIGHT DROP DURING PROCESSING
    Publication number: 20120239135
    Abstract: A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
    Type: Application
    Filed: May 25, 2012
    Publication date: September 20, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Byron Lambert, Yunbing Wang, James Oberhauser
  • Methods for crimping a polymeric stent onto a delivery balloon
    Patent number: 8261423
    Abstract: A medical device-includes a polymer stent crimped to a catheter having an expansion balloon. The stent is crimped to the balloon by a process that includes heating the stent to a temperature below the polymer's glass transition temperature to improve stent retention without adversely affecting the mechanical characteristics of the stent when later deployed to support a body lumen.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: September 11, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Kevin F. Jow, Arlene Sucy Yang, Yunbing Wang, Kathleen W. Yan
  • Implantable medical devices fabricated from polymer blends with star-block copolymers
    Patent number: 8262723
    Abstract: Implantable medical devices are fabricated from polymer blends with star-block copolymers. The polymer blends include a biodegradable matrix polymer blended with a biodegradable star-block copolymer. The copolymer has at least three arms and the arms include inner segments and outer segments. The inner segments form a discrete phase within a continuous phase, the continuous phase including the matrix polymer and the outer segments. The segments can include units having acidic degradation products that enhance the degradation rate of the blend.
    Type: Grant
    Filed: April 9, 2007
    Date of Patent: September 11, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, David C. Gale, Bin Huang
  • Method for fabricating a stent with nucleating agent
    Patent number: 8252215
    Abstract: The use of nucleating agents to manufacture polymeric stents is disclosed. The resulting stents may have increased crystallinity, decreased crystal size, increased mechanical properties, and faster degradation times.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: August 28, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • Method to minimize molecular weight drop of poly(L-lactide) stent during processing
    Patent number: 8207240
    Abstract: A method to reduce or minimize the reduction in molecular weight of a stent during processing is disclosed. The stent has a scaffolding including a polymer formulation comprising PLLA and polymandelide. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
    Type: Grant
    Filed: September 14, 2009
    Date of Patent: June 26, 2012
    Assignee: Abbott Cardiovascular Systems Inc
    Inventors: Byron Lambert, Yunbing Wang, James Oberhauser
  • Implantable medical devices with elastomeric block copolymer coatings
    Patent number: 8202528
    Abstract: Implantable medical devices with elastomeric block copolymer coatings are disclosed.
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: June 19, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Daniel Castro