Patents by Inventor Yunfang Wang

Yunfang Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11149253
    Abstract: Provided are a small molecule compound combination for reprogramming digestive tract derived epithelial cells to endodermal stem/progenitor cells, a reprogramming method and an application. Human gastric epithelial cells (hGECs) are used as initiating cells, human gastric subepithelial myofibroblasts (aGSEMFs) are used as a trophoblast, a compound combination having all or a plurality of FBP, Bay K 8644, Bix01294, SB431542 or A813-01, VPA, RG108, PD0325901 and PS48 including SB or A83 is used to reprogram digestive tract derived epithelial cells to endodermal stem/progenitor cells, and the endodermal stem/progenitor cells can be used for inducing differentiation towards liver cells, pancreatic beta cells and intestinal cells.
    Type: Grant
    Filed: May 27, 2017
    Date of Patent: October 19, 2021
    Assignee: INSTITUTE OF TRANSFUSION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PEOPLE'S LIBRATION ARMY OF CHINA
    Inventors: Yunfang Wang, Shuyong Wang, Wencheng Zhang, Jinhua Qin, Xuan Wang, Mingyang Chang, Fang Yan, Xuetao Pei
  • Publication number: 20200385682
    Abstract: Provided are a small molecule compound combination for reprogramming digestive tract derived epithelial cells to endodermal stem/progenitor cells, a reprogramming method and an application. Human gastric epithelial cells (hGECs) are used as initiating cells, human gastric subepithelial myofibroblasts (aGSEMFs) are used as a trophoblast, a compound combination having all or a plurality of FBP, Bay K 8644, Bix01294, SB431542 or A813-01, VPA, RG108, PD0325901 and PS48 including SB or A83 is used to reprogram digestive tract derived epithelial cells to endodermal stem/progenitor cells, and the endodermal stem/progenitor cells can be used for inducing differentiation towards liver cells, pancreatic beta cells and intestinal cells.
    Type: Application
    Filed: May 27, 2017
    Publication date: December 10, 2020
    Inventors: Yunfang WANG, Shuyong WANG, Wencheng ZHANG, Jinhua QIN, Xuan WANG, Mingyang CHANG, Fang YAN, Xuetao PEI
  • Patent number: 10640747
    Abstract: The present invention provides biomatrix scaffolds for industrial scale dispersal.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: May 5, 2020
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Marsha Lynn Roach, Richard Harold Malavarca, Yunfang Wang, Lola M. Reid
  • Publication number: 20200002667
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: February 12, 2019
    Publication date: January 2, 2020
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Reid, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • Publication number: 20190188430
    Abstract: A container locating system and method, and an electronic tag are disclosed. The system includes: an electronic tag, a reader/writer and a detection module. The electronic tag is disposed on the container and stores product identification information of the container; the detection module transmits a first level signal to the electronic tag when the detection module detects that the stored electrical capacity of the electronic tag is greater than a preset electrical capacity threshold; the electronic tag transmits, upon receiving the first level signal, an information acquisition signal to other electronic tags within a designated area to cause said other electronic tags to transmit their respective stored product identification information to the electronic tag; the reader/writer reads product identification information stored in the electronic tag to determine a location of a container.
    Type: Application
    Filed: August 31, 2018
    Publication date: June 20, 2019
    Inventors: Zhifeng CAO, Yunfang WANG, Fengyu DAI, Yanyin HUO
  • Patent number: 10246678
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: April 2, 2019
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Reid, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • Publication number: 20190044472
    Abstract: A groove type mounting bracket, a photovoltaic power generation unit and a method for mounting a photovoltaic power generation assembly are provided. The groove type mounting bracket includes a support plate and grooves arranged on the sides of the support plate. The groove is suitable for snap-fitting with a vertical member which extends on a building surface and has a projection on the side thereof. The photovoltaic power generation unit includes a photovoltaic power generation assembly and a groove type mounting bracket of the application. By using the groove type mounting bracket of the application, the flexible photovoltaic assembly can be directly snap-fitted and mounted on the standing seam roof.
    Type: Application
    Filed: August 2, 2018
    Publication date: February 7, 2019
    Inventors: Fengyu Dai, Yunfang Wang, Yanyin Huo, Zhifeng Cao
  • Publication number: 20190024043
    Abstract: The present invention provides biomatrix scaffolds for industrial scale dispersal.
    Type: Application
    Filed: April 12, 2018
    Publication date: January 24, 2019
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Marsha Lynn ROACH, Richard Harold MALAVARCA, Yunfang WANG, Lola M. REID
  • Publication number: 20190013770
    Abstract: A road surface power generation assembly is provided, which includes a substrate, a solar cell chip and a glass layer. The glass layer includes an upper glass layer and a lower glass layer which are secured through a sheet adhesive layer. The solar cell chip is arranged between the lower glass layer and the substrate.
    Type: Application
    Filed: July 5, 2018
    Publication date: January 10, 2019
    Applicant: BEIJING APOLLO DING RONG SOLAR TECHNOLOGY CO., LTD..
    Inventors: Yunfang WANG, Fengyu DAI, Yanyin HUO, Zhifeng CAO
  • Publication number: 20190013769
    Abstract: A road surface power generation system is provided, which includes a glass layer, a solar cell chip, a substrate and a heating device. The solar cell chip is arranged between the glass layer and the substrate. The heating device is arranged on the glass layer or the substrate. In the road surface power generation system, the heating device is arranged on the glass layer or the substrate, for heating the glass layer, such that frost, snow and ice accumulated on the glass layer can be melted, thereby enhancing the light absorption rate of the solar cell chip, and improving the power generation efficiency.
    Type: Application
    Filed: July 5, 2018
    Publication date: January 10, 2019
    Applicant: BEIJING APOLLO DING RONG SOLAR TECHNOLOGY CO., LTD.
    Inventors: Yunfang WANG, Fengyu DAI, Yanyin HUO, Zhifeng CAO
  • Publication number: 20180367091
    Abstract: A reel-type packaged flexible assembly module is provided. The reel-type packaged flexible assembly module includes a packaging cloth, cables and two or more flexible photovoltaic assemblies. The two or more flexible photovoltaic assemblies are bonded to one packaging cloth. The two or more flexible photovoltaic assemblies are connected in series through cables.
    Type: Application
    Filed: June 20, 2018
    Publication date: December 20, 2018
    Inventors: Yunfang Wang, Fengyu Dai, Yanyin Huo, Zhifeng Cao
  • Publication number: 20180367083
    Abstract: A trailer-type energy vehicle includes a trailer-type compartment, a reel-type packaged flexible photovoltaic power generation device and an electrical system. The reel-type packaged flexible photovoltaic power generation device is arranged in the trailer-type compartment and includes a winding mechanical device and a reel-type flexible photovoltaic power generation strip. The reel-type flexible photovoltaic power generation strip is wound on the winding mechanical device. The electrical system is connected with the reel-type flexible photovoltaic power generation strip.
    Type: Application
    Filed: June 20, 2018
    Publication date: December 20, 2018
    Inventors: Yunfang Wang, Fengyu Dai, Yanyin Huo, Zhifeng Cao
  • Publication number: 20180367084
    Abstract: A portable reel-type solar power generation device and a reel-type solar power generation device are provided. The portable reel-type solar power generation device includes a roller, a moving apparatus and a solar cell packaged assembly. The solar cell packaged assembly is configured to be wound on the roller which is arranged on the moving apparatus.
    Type: Application
    Filed: June 20, 2018
    Publication date: December 20, 2018
    Inventors: Yunfang Wang, Fengyu Dai, Yanyin Huo, Zhifeng Cao
  • Patent number: 9944896
    Abstract: The present invention provides biomatrix scaffolds for industrial scale dispersal.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: April 17, 2018
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Marsha Lynn Roach, Richard Harold Malavarca, Yunfang Wang, Lola Cynthia McAdams Reid
  • Patent number: 9750770
    Abstract: A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem cells, hepatic stem cells, pancreatic stem cells or their descendants, committed progenitor cells, from healthy tissue of the patient or of the biliary tree of a non-autologous donor and engrafting the cells into the wall of bile ducts near to the organ to be treated. The graft consists of stem cells or progenitors that are admixed with biomaterials and, optionally, with cytokines and/or native epithelial-mesenchymal cells appropriate for the maturational lineage stage of the cells to be engrafted.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: September 5, 2017
    Assignees: The University of North Carolina at Chapel Hill, University of Miami-Diabetes Research Institute, Sapienza Università Di Roma
    Inventors: Lola M. Reid, Yunfang Wang, David A. Gerber, Giacomo Lanzoni, Luca Inverardi, Juan Dominguez-Bendala, Domenico Alvaro, Vincenzo Cardinale, Eugenio Gaudio, Guido Carpino
  • Publication number: 20170015974
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: July 27, 2016
    Publication date: January 19, 2017
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Yunfang WANG, Lola Cynthia McAdams REID, Mitsuo YAMAUCHI, Cai-Bin CUI, Andrew Zhuang WANG, Michael Edward WERNER
  • Patent number: 9533013
    Abstract: A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem cells, hepatic stem cells, pancreatic stem cells or their descendants, committed progenitor cells, from healthy tissue of the patient or of the biliary tree of a non-autologous donor and engrafting the cells into the wall of bile ducts near to the organ to be treated. The graft consists of stem cells or progenitors that are admixed with biomaterials and, optionally, with cytokines and/or native epithelial-mesenchymal cells appropriate for the maturational lineage stage of the cells to be engrafted.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: January 3, 2017
    Assignees: University of North Carolina at Chapel Hill, Sapienza Università Di Roma, University of Miami—Diabetes Research Institute
    Inventors: Lola M. Reid, Yunfang Wang, David A. Gerber, Giacomo Lanzoni, Luca Inverardi, Juan Dominguez-Bendala, Domenico Alvaro, Vincenzo Cardinale, Eugenio Gaudio, Guido Carpino
  • Publication number: 20160058798
    Abstract: A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem cells, hepatic stem cells, pancreatic stem cells or their descendants, committed progenitor cells, from healthy tissue of the patient or of the biliary tree of a non-autologous donor and engrafting the cells into the wall of bile ducts near to the organ to be treated. The graft consists of stem cells or progenitors that are admixed with biomaterials and, optionally, with cytokines and/or native epithelial-mesenchymal cells appropriate for the maturational lineage stage of the cells to be engrafted.
    Type: Application
    Filed: November 9, 2015
    Publication date: March 3, 2016
    Applicants: University of North Carolina at Chapel Hill, Sapienza Università di Roma, University of Miami
    Inventors: Lola M. REID, Yunfang WANG, David A. GERBER, Giacomo LANZONI, Luca INVERARDI, Juan DOMINGUEZ-BENDALA, Domenico ALVARO, Vincenzo CARDINALE, Eugenio GAUDIO, Guido CARPINO
  • Publication number: 20160024463
    Abstract: The present invention provides biomatrix scaffolds for industrial scale dispersal.
    Type: Application
    Filed: October 13, 2015
    Publication date: January 28, 2016
    Applicants: PHOENIXSONGS BIOLOGICALS, THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Marsha Lynn ROACH, Richard Harold MALAVARCA, Yunfang WANG, Lola Cynthia McAdams REID
  • Patent number: 9102913
    Abstract: The present invention provides biomatrix scaffolds for industrial scale dispersal.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: August 11, 2015
    Assignees: The University of North Carolina at Chapel Hill, PhoenixSongs Biologicals
    Inventors: Marsha Lynn Roach, Richard Harold Malavarca, Yunfang Wang, Lola Cynthia McAdams Reid