Patents by Inventor Yunfang Wang

Yunfang Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMATRIX SCAFFOLDS
    Publication number: 20150110753
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: August 8, 2014
    Publication date: April 23, 2015
    Applicant: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Yunfang WANG, Lola Cynthia McAdams REID, Mitsuo YAMAUCHI, Cai-Bin CUI, Andrew Zhuang WANG, Michael Edward WERNER
  • METHOD OF TREATING PANCREATIC AND LIVER CONDITIONS BY ENDOSCOPIC-MEDIATED (OR LAPAROSCOPIC-MEDIATED) TRANSPLANTATION OF STEM CELLS INTO/ONTO BILE DUCT WALLS OF PARTICULAR REGIONS OF THE BILIARY TREE
    Publication number: 20140301985
    Abstract: A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem cells, hepatic stem cells, pancreatic stem cells or their descendants, committed progenitor cells, from healthy tissue of the patient or of the biliary tree of a non-autologous donor and engrafting the cells into the wall of bile ducts near to the organ to be treated. The graft consists of stem cells or progenitors that are admixed with biomaterials and, optionally, with cytokines and/or native epithelial-mesenchymal cells appropriate for the maturational lineage stage of the cells to be engrafted.
    Type: Application
    Filed: March 12, 2014
    Publication date: October 9, 2014
    Applicants: University of North Carolina at Chapel Hill, Sapienza Università di Roma, Diabetes Research Institute
    Inventors: Lola M. REID, Yunfang WANG, David A. GERBER, Giacomo LANZONI, Luca INVERARDI, Juan DOMINGUEZ-BENDALA, Domenico ALVARO, Vincenzo CARDINALE, Eugenio GAUDIO, Guido CARPINO
  • Biomatrix scaffolds
    Patent number: 8802081
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: August 12, 2014
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Reid, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • Biomatrix Scaffolds
    Publication number: 20130195811
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: July 1, 2011
    Publication date: August 1, 2013
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Ried, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • Biomatrix Scaffolds for Industrial Scale Dispersal
    Publication number: 20130137176
    Abstract: The present invention provides biomatrix scaffolds for industrial scale dispersal.
    Type: Application
    Filed: July 1, 2011
    Publication date: May 30, 2013
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Marsha Lynn Roach, Richard Harold Malavarca, Yunfang Wang, Lola Cynthia McAdams Reid
  • Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same
    Publication number: 20110135610
    Abstract: The present invention relates to a multipotent stem cell, multipotent cell populations, and an enriched multipotent cell population, each found in fetal, neonatal, pediatric, and adult biliary tree tissue and up to 72 hours post mortem (although preferentially, within 10 hours post mortem) and capable of maturing into multiple endodermal tissues that include liver, biliary and pancreatic tissues. The multipotent stem/progenitor cell and cell populations are found in peribiliary glands, and progenitors descending from them are present throughout the biliary tree including in the gallbladder. High numbers of the peribiliary glands are found in the branching locations of the biliary tree such as hilum, common hepatic duct, cystic duct, common duct, common hepato-pancreatic duct and gallbladder. Related multipotent cells, multipotent cell populations and their descendent progenitors are found throughout the biliary tree including in the gall bladder, which does not have peribiliary glands.
    Type: Application
    Filed: October 28, 2010
    Publication date: June 9, 2011
    Inventors: Lola M. Reid, Yunfang Wang, Vincenzo Cardinale, Eugenio Gaudio, Guido Carpino, Domenico Alvaro, Cai-Bin Cui