Patents by Inventor Yung-Hsiang Lin

Yung-Hsiang Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220168377
    Abstract: A peptide composition and methods for slimming and/or for promoting the growth of probiotics using early harvested rice prebiotics are provided. The peptide composition or the early harvested rice prebiotics includes at least one peptide as set forth in: SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 and SEQ, ID NO: 8.
    Type: Application
    Filed: November 5, 2021
    Publication date: June 2, 2022
    Inventors: YUNG-HSIANG LIN, PEI-YI WU
  • Patent number: 11344587
    Abstract: Provided is a method of improving urogenital health, including administering to a subject a composition including an effective amount of a Lactobacillus johnsonii strain deposited under the accession number of DSM 33288 or a metabolite thereof. The Lactobacillus johnsonii strain, which is a probiotic, and metabolites thereof inhibit the growth of common pathogenic bacteria and fungi causing genitourinary tract infections, thereby reducing the risk of genitourinary tract infections or alleviating symptoms thereof. Also provided is a composition for improving urogenital health which includes the Lactobacillus johnsonii strain.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: May 31, 2022
    Assignee: TCI CO., LTD.
    Inventors: Yung-Hsiang Lin, Chu-Han Huang, Cheng-Yu Ho
  • Patent number: 11324782
    Abstract: The present invention provides a use of herb ferment for preparing a composition for preventing and/or treating obesity; wherein, the herb is Abelmoschus esculentus. The fermentation process of the present invention can enhance the content of total polysaccharide in the herb ferment, and effectively increase the amylase inhibition rate and the glucosidase inhibition rate of the herb ferment to effectively inhibit the decomposition and absorption of starch and glucoside. The herb ferment of the present invention can also effectively reduce the blood glucose of subjects after meals, and can effectively reduce the body weight, BMI value, waist circumference, visceral fat, average whole body fat percentage, and average body fat percentage, and can be effectively used to regulate blood glucose and blood lipids for weight loss. The herb ferment is prepared by fermenting the herb extract to yeast and lactic acid bacteria.
    Type: Grant
    Filed: December 26, 2019
    Date of Patent: May 10, 2022
    Assignee: TCI CO., LTD.
    Inventors: Yung-Hsiang Lin, Wei-Hsiu Chuang
  • Publication number: 20220125708
    Abstract: Provided is a method for skin conditioning comprising administering to a subject in need thereof a composition comprising a Dan Feng peony extract, where the Dan Feng peony extract is extracted from flowers of Dan Feng peony. The Dan Feng peony extract is used to increase the production of hyaluronic acid, maintain the structure of skin keratinocytes, and regulate the moisture content of skin cells.
    Type: Application
    Filed: October 26, 2021
    Publication date: April 28, 2022
    Applicant: TCI CO., LTD.
    Inventors: YUNG-HSIANG LIN, WEI-CHUN LEE
  • Publication number: 20220125758
    Abstract: A preparation method for a liposome having the ability to stably encapsulate an active ingredient is provided. The preparation method includes providing a mixture and homogenizing the mixture at 300 bar-400 bar to form a liposome suspension. The mixture includes 0.1 wt % of lecithin, 2 wt %-5 wt % of Arabic gum and 63.9125 wt %-97.9 wt % of a solvent. The liposome suspension includes a plurality of liposomes.
    Type: Application
    Filed: December 24, 2020
    Publication date: April 28, 2022
    Inventors: YUNG-HSIANG LIN, HUI-HSUAN LIU
  • Patent number: 11304892
    Abstract: Alteromonas macleodii Dow02-2 is provided, wherein the Alteromonas macleodii Dow02-2 was deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen, DSMZ) under the accession number DSM33380, and its metabolites comprise 2-hydroxy-3-methylbutyric acid. A method for providing 2-hydroxy-3-methylbutyric acid is also provided, wherein the method comprises isolating the 2-hydroxy-3-methylbutyric acid from metabolites of Alteromonas macleodii Dow02-2 of biologically pure culture. A method for at least one of increasing expression of TGM1 gene, increasing expression of KRT1 gene, increasing expression of KRT10 gene, increasing expression of KRT14 gene, increasing expression of FLG gene, increasing expression of GBA gene, and increasing expression of HAS3 gene is also provided, wherein the method comprises administering to a subject in need thereof an effective amount of 2-hydroxy-3-methylbutyric acid.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: April 19, 2022
    Assignee: TCI Co., Ltd.
    Inventors: Chu-Han Huang, Huan-You Lin, Cheng-Yu Ho, Yung-Hsiang Lin
  • Publication number: 20220088095
    Abstract: The present disclosure provides a method for regulating expression of IL-1? gene, MMP1a gene and TIMP1 gene of chondrocytes using a Lactobacillus plantarum strain TCI227.
    Type: Application
    Filed: December 7, 2021
    Publication date: March 24, 2022
    Inventors: YUNG-HSIANG LIN, Chu-Han Huang, Cheng-Yu Ho
  • Patent number: 11278582
    Abstract: Provided is a composition for reducing the fat content of fat-producing cells and applications thereof. The composition includes plant extracts such as a blueberry extract and a black tea extract.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: March 22, 2022
    Assignee: TCI CO., LTD.
    Inventors: Yung-Hsiang Lin, I-Hui Chen, Kai-Wen Kan, Fu Chen Liu, Ciao-Ting Chen
  • Patent number: 11273189
    Abstract: Lactobacillus plantarum TCI378 is provided. The Lactobacillus plantarum TCI378 was deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen, DSMZ) under the accession number DSM 32451. A method for losing fat and/or improving gastrointestinal functions is also provided. The method comprises administering to a subject in need an effective amount of a composition, wherein the composition comprises Lactobacillus plantarum TCI378 and/or its metabolites.
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: March 15, 2022
    Assignee: TCI CO., LTD
    Inventors: Yung-Hsiang Lin, Chu-Han Huang, Cheng-Yu Ho
  • Publication number: 20220062158
    Abstract: The present invention discloses yeast powder rich in nicotinamide mononucleotide, a preparation method and uses thereof. The preparation method includes: preparing a first medium, a second medium, and a third medium; inoculating the first medium with yeast for fermentation to obtain a first fermentation broth; inoculating the second medium with the first fermentation broth for fermentation to obtain a second fermentation broth; inoculating the third medium with the second fermentation broth for fermentation to obtain a third fermentation broth; centrifuging the third fermentation broth to obtain a fermented product; and drying the fermented product to obtain the yeast powder. Components of the first medium, the second medium and the third medium include nicotinamide, tryptophan and niacin. The content of nicotinamide mononucleotide in the yeast powder is at least 5000 ppm.
    Type: Application
    Filed: August 25, 2021
    Publication date: March 3, 2022
    Inventors: YUNG-HSIANG LIN, PEI-YI WU
  • Publication number: 20220062160
    Abstract: A method for inhibiting skin acne formation, reducing Cutibacterium acnes secretions, and/or reducing advanced glycation end-products (AGEs) comprising administering to a subject in need thereof a composition comprising an effective amount of a Wasabia japonica leaf extract is provided. The composition is used for increasing skin water content, improving skin firmness, reducing skin wrinkles, inhibiting the production of skin wrinkles, inhibiting the production of skin spots, inhibiting the production of melanin, and inhibiting the production of acne.
    Type: Application
    Filed: October 29, 2021
    Publication date: March 3, 2022
    Inventors: YUNG-HSIANG LIN, TSAI-HAN YAO
  • Publication number: 20220054388
    Abstract: A method for preventing aging of a subject in need thereof includes administering to the subject a composition including a bioactive compound. The bioactive compound is a peptide, and includes at least one amino acid sequence as set forth in SEQ ID NO: 1 to SEQ ID NO: 6. Each of the amino acid sequence is a peptide of fish skin. The composition has anti-aging and cellular health maintaining capabilities. In addition, the composition can also be used for increasing collagen content, improving skin collagen density, improving skin moisture, minimizing skin pores, reducing wrinkles or achieving a combination of these effects.
    Type: Application
    Filed: November 17, 2020
    Publication date: February 24, 2022
    Inventors: YUNG-HSIANG LIN, YU-LING WANG
  • Publication number: 20220054398
    Abstract: The present disclosure provides a use of Rubus fruticosus extract for manufacturing a skincare composition, where the composition is used for reducing oxidative damage caused by reactive oxygen species in cells, reducing the amount of hemoglobin in skin, inhibiting melanin production, reducing skin redness spots, and enhance the skin's moisturizing ability.
    Type: Application
    Filed: August 20, 2021
    Publication date: February 24, 2022
    Inventors: YUNG-HSIANG LIN, WEI-CHUN LEE
  • Publication number: 20220040268
    Abstract: A method for improving a skin condition of a subject in need thereof includes administering to the subject a composition including a bioactive compound. The bioactive compound is a peptide, and includes at least one amino acid sequence as set forth in SEQ ID NO: 1 to SEQ ID NO: 11. Each of the amino acid sequence is a peptide of fish skin.
    Type: Application
    Filed: November 17, 2020
    Publication date: February 10, 2022
    Inventors: YUNG-HSIANG LIN, YU-LING WANG
  • Publication number: 20220001296
    Abstract: A system for increasing the extraction of an active ingredient includes a vacuum quick-dissolving tank, a mixer, a solid-liquid separator, and a homogenizer. The vacuum quick-dissolving tank receives a sample. The mixer is connected to the vacuum quick-dissolving tank, and provides an aqueous solvent to be mixed with the sample. Heating, cooling, stirring, and vacuuming in the vacuum quick-dissolving tank make the sample dissolve and emulsify repeatedly between the vacuum quick-dissolving tank and the mixer to produce a mixture, which is output by the vacuum quick-dissolving tank. The solid-liquid separator receives the mixture output from the vacuum quick-dissolving tank for solid-liquid separation, and outputs an isolated sample liquid. The homogenizer receives the sample liquid output from the solid-liquid separator, performs high-pressure homogenization to obtain an extract liquid containing an active ingredient, and outputs the extract liquid.
    Type: Application
    Filed: February 8, 2021
    Publication date: January 6, 2022
    Inventors: YUNG-HSIANG LIN, CHIEN-YU LU, JIN-JIA WANG
  • Patent number: 11207359
    Abstract: The present invention provides a cholesterol reducing probiotic strain, composition thereof and use thereof. The probiotic strain is Lactobacillus plantarum TCI507, which itself and its metabolites can effectively reduce the cholesterol content, enhance the gene expression level of SCARB1, APOA1, and LDLR to promote the effect of cholesterol metabolism, and can effectively reduce the total cholesterol and the low-density lipoprotein in human blood.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: December 28, 2021
    Assignee: TCI CO., LTD.
    Inventor: Yung-Hsiang Lin
  • Publication number: 20210395304
    Abstract: The present disclosure provides peptides comprising a motif having four amino acids, wherein each of the amino acids at N-terminus and C-terminus of the sequence independently has a same or different positively charged side chain, and each of the amino acids between the N-terminal and C-terminal of the motif independently has a same or different uncharged side chain. The present disclosure surprisingly found that these peptides have advantageous effects in inhibiting or decreasing collagen breakdown, increasing production of collagen, elastin and/or hyaluronic acid, retarding aging, improving skin and inhibiting inflammation.
    Type: Application
    Filed: September 14, 2021
    Publication date: December 23, 2021
    Inventors: Yung-Hsiang LIN, Yu-Ling WANG
  • Patent number: 11202812
    Abstract: The present invention provides a method of reducing body fat, comprising administering a composition comprising an effective amount of Lactobacillus paracasei or a metabolite thereof to a subject in need thereof. The Lactobacillus paracasei or the metabolite thereof can effectively convert the fatty acid into conjugated linoleic acid, inhibit the accumulation of fat and promote the decomposition of fat in fat cells, and can effectively reduce the percentage of body fat, waist circumference, and hip circumference, and simultaneously increase the muscle mass of the subject.
    Type: Grant
    Filed: December 31, 2019
    Date of Patent: December 21, 2021
    Assignee: TCI CO., LTD.
    Inventors: Yung-Hsiang Lin, Chu-Han Huang, Cheng-Yu Ho
  • Patent number: 11173188
    Abstract: Provided is a method of preparing an orange peel ferment, an orange peel ferment obtained therefrom, and a method for reducing fat accumulation, sleep disturbance, and cancer risk. The orange peel ferment assists obese individuals to slim down via multiple mechanisms including reducing the fat content of adipocytes, promoting lysis of triglycerides in adipocytes, and enhancing the expression of genes involved in fat metabolism, and also reduces sleep disturbance through normalizing circadian rhythm and lowers cancer risk through suppressing expression of cancer risk genes.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: November 16, 2021
    Assignee: TCI CO., LTD.
    Inventor: Yung-Hsiang Lin
  • Patent number: 11173107
    Abstract: A method for at least one of whitening skin, improving skin condition, protecting skin, and treating skin disease is provided, wherein the method comprises administering to a subject in need an effective amount of a Pyrenaria buisanensis extract. A method for at least one of preventing cardiovascular disease, treating cardiovascular disease, preventing diabetes, treating diabetes, preventing neurodegenerative disease, and treating neurodegenerative disease is also provided, wherein the method comprises administering to a subject in need an effective amount of a Pyrenaria buisanensis extract.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: November 16, 2021
    Assignee: TCI CO., LTD.
    Inventors: Yung-Hsiang Lin, Yu-Ting Lin