Abstract: This invention relates to an antimicrobial skin sanitizing composition for disinfecting skin, and particularly, hands. The composition contains at least 60 percent of an aliphatic alcohol having from 1 to 4 carbon atoms, from about 0.1 to about 5 weight percent of a thickening agent, and an effective amount of a GRAS or amino acid neutralizer to neutralize the thickening agent.

Abstract: This invention relates to an antimicrobial skin sanitizing composition for disinfecting skin, and particularly, hands. The composition contains at least 60 percent of an aliphatic alcohol having from 1 to 4 carbon atoms, from about 0.1 to about 5 weight percent of a thickening agent, and an effective amount of a GRAS or amino acid neutralizer to neutralize the thickening agent.

Abstract: A method is provided for mulching an agricultural soil bed using a biodegradable protein mulch material. The method includes the preparation of a film forming solution of a film forming protein material. The film forming protein solution is then sprayed directly onto a surface of an agricultural soil bed. The solution dries to form a thin film of protein material on the surface of the agricultural soil bed. The protein material may comprise a plant protein, a milk protein, an animal protein, a whey protein, casein, an egg protein or gelatin. Following a harvest, the mulch material, which is biodegradable, may simply be plowed under.

Abstract: Methods for cleaning soiled contact lenses are disclosed. The methods involve contacting the soiled lens with a cleaning composition comprising carbon dioxide and carbonic acid as cleansing agents. The cleaning compositions do not require abrasive agents such as polymeric beads, nor ocularly irritating agents such as enzymes or surfactants in order to effectively clean proteinaceous and nonproteinaceous deposits from the surface of contact lenses.

Abstract: Simple, efficacious, easily manufacturable, convenient to use and cost-effective contact lens care cleaning compositions comprising carbon dioxide and carbonic acid as cleansing agents are disclosed. The compositions do not require abrasive agents such as polymeric beads, nor ocularly irritating agents such as enzymes or surfactants in order to effectively clean proteinaceous and nonproteinaceous deposits from the surface of contact lenses. Also disclosed is a one-step cleaning and disinfecting regimen, whereby an effervescent tablet composition capable of generating carbon dioxide and carbonic acid is dissolved in a disinfecting solution or rinsing/disinfecting/storage solution.

Abstract: Ophthalmic suspensions containing brinzolamide or brinzolamide and a beta-blocker and processes for manufacturing the suspensions are disclosed.

Abstract: Simple, efficacious, easily manufacturable, convenient to use and cost-effective contact lens care cleaning compositions comprising carbon dioxide and carbonic acid as cleansing agents are disclosed. The compositions do not require abrasive agents such as polymeric beads, nor ocularly irritating agents such as enzymes or surfactants in order to effectively clean proteinaceous and nonproteinaceous deposits from the surface of contact lenses. Also disclosed is a one-step cleaning and disinfecting regimen, whereby an effervescent tablet composition capable of generating carbon dioxide and carbonic acid is dissolved in a disinfecting solution or rinsing/disinfecting/storage solution.

Abstract: Aqueous pharmaceutical compositions containing a synergistic combination of a quinolone and a polystyrene sulfonic acid polymer are described, wherein the compositions are clear solutions which are comfortable and have sustained release. Methods for use of the compositions are also disclosed. This type of formulation is particularly useful with ciprofloxacin-type quinolones by greatly increasing the solubility of these quinolones, making it feasible to have aqueous solutions containing such quinolones at or near physiological pH.

Abstract: Stable formulations of positively charged, hydrolytically unstable drug compounds are obtained by adding a sulfated polyvinyl alcohol copolymer to the formulations.

Abstract: The present invention is directed to topical ophthalmic formulations of carbonic anhydrase inhibitors and polyethoxylated derivatives of castor oil. Methods for using the formulations for treating and controlling glaucoma and ocular hypertension are also disclosed.

Abstract: Compositions for controlling glaucoma and ocular hypertension are disclosed.

Abstract: Certain anionic surfactants are used to enhance antimicrobial effectiveness in comfortable, sustained release ophthalmic compositions containing polyelectrolytes, such as carboxyvinyl polymers, polystyrene sulfonic acid polymers and cationic exchange resins, as well as at least one active ingredient.

Abstract: Certain anionic surfactants are used to enhance antimicrobial effectiveness in comfortable, sustained release ophthalmic compositions containing polyelectrolytes, such as carboxyvinyl polymers, polystyrene sulfonic acid polymers and cationic exchange resins, as well as at least one active ingredient.

Abstract: Ophthalmic pharmaceutical vehicles which become viscous on contacting the eye are disclosed. Ophthalmic compositions of the vehicle and a pharmaceutically active drug are also disclosed.

Abstract: Universal ophthalmic pharmaceutical vehicles which increase in viscosity upon instillation in the eye are disclosed. Ophthalmic compositions of the universal vehicle and a pharmaceutically active drug are also disclosed. In one embodiment, the vehicle gels upon instillation in the eye. In another embodiment, suspension vehicles having superior physical stability are provided.

Abstract: Disclosed are nonstinging, sustained release ophthalmic formulations. The formulations comprise a cationic drug, an acidic mucomimetic polymer and a polystyrene sulfonic acid polymer. In particular, formulations for the control of intraocular pressure and glaucoma are disclosed. Methods for use of the formulations are also disclosed.

Abstract: A method of preparing aqueous pharmaceutical compositions containing a synergistic combination of trimethoprim and sodium sulfacetamide is described. The method results in a significant improvement in the aqueous solubility of trimethoprim due to a favorable interaction between the trimethoprim and sodium sulfacetamide which is dependent on a mildly acidic pH.