Abstract: An embodiment provides a state estimation device including: an acquisition unit configured to acquire a state variable including an observation value obtained by observing a steersman who steers an moving object; and an estimation unit including a state model having a correlation between the state variable and a cognitive load during steering of the steersman and configured to estimate a state of the steersman from the state variable acquired by the acquisition unit.

Abstract: Provided is a binder composition for a non-aqueous secondary battery negative electrode capable of producing a slurry composition having suppressed foaming and forming a negative electrode mixed material layer having excellent resistance to peeling. The binder composition for a non-aqueous secondary battery negative electrode contains a particulate binder and water. The particulate binder includes a polymer including an ethylenically unsaturated carboxylic acid monomer unit, an aromatic vinyl monomer unit, and an aliphatic conjugated diene monomer unit. When a film of the particulate binder is formed, the film has a degree of swelling of insoluble content in tetrahydrofuran of 300 mass % to 1500 mass % and an amount of insoluble content in tetrahydrofuran of 85 mass % to 99 mass %. A ratio of viscosity at pH 8.0 relative to viscosity at pH 3.0 of the binder composition when set to a solid content concentration of 30 mass % is 1.5 to 200.

Abstract: The present disclosure provides bicyclic pyridine derivatives. A compound represented by formula I: or a pharmaceutically acceptable salt thereof, wherein X is a oxygen atom, sulfur atom, NR, or CR?R?, n is 0 or 1, R1, R2a, R2b, R2c, R2d, R, R? and R? are each independently a hydrogen atom, a halogen atom, optionally substituted C1-6 alkyl, or an optionally substituted C6-10 aryl, or two of R2a, R2b, R2c, R2d, R, R?, and R?, together with a carbon atom or a nitrogen atom to which they are attached, form a 3- to 6-membered saturated carbocyclic ring or saturated heterocyclic ring, and R3a, R3b, R3c and R5a and R5b, are as defined in the description.

Abstract: A 6-aminopyrazolopyrimidine compound, or a pharmaceutically acceptable salt thereof, having NLRP3 inflammasome inhibitory activity, a pharmaceutical composition comprising the same, and their medical use, etc., are provided. A compound of Formula [IA]: or a pharmaceutically acceptable salt thereof, wherein a partial structure: is a structure of the following formula: etc. wherein R4 is hydrogen or C1-4 alkyl, in which the alkyl may be optionally substituted with hydroxy or cyano, Ring group CyA is a group of the following formula: etc. wherein R6 and R7 are, each independently, hydrogen, hydroxy, cyano, C1-6 alkyl, etc., R8 and R9 are, each independently, hydrogen, C1-4 alkyl, or C1-4 haloalkyl, R10 is hydrogen, cyano, C1-6 alkyl, etc.), R1 is hydrogen or C1-4 alkyl, R2A and R3A are, each independently, hydrogen, C1-6 alkyl etc.

Abstract: An imaging system located on a moving body, includes an imaging device, a blur correction device, and an image processor. Based on a subject distance from the imaging device to the object to be imaged, the blur correction device sets a blur correction amount of blur in a movement direction caused when the imaging device captures images during movement of the moving body. The blur correction device corrects blur during image capturing by use of the set blur correction amount. The image processor calculates a pixel movement amount of a feature portion common to a first image and a second image. Based on the pixel movement amount and the movement amount of the moving body, the blur correction device calculates a third distance as the subject distance.

Abstract: The manufacturing method of the 1,4-dioxane derivative represented by Formula (2) and/or Formula (10) includes reacting water, an inorganic base, and a fluoroalkene oxide represented by Formula (1). The manufacturing method of the (1,3-dioxolane)-2-carboxylic acid derivative includes manufacturing the 1,4-dioxane derivative represented by Formula (2) and/or Formula (10) by the above manufacturing method and a manufacturing method of the (1,3-dioxolane)-2-carboxylic acid derivative includes manufacturing the 1,4-dioxane derivative represented by Formula (2) and/or Formula (10) comprising ring reduction under heating. In Formula (1), R represents a fluorine atom or a fluoroalkyl group. In Formula (2) and in Formula (10), R represents a fluorine atom or a fluoroalkyl group, two R's present are the same as or different from each other, and M?+ represents a counter cation.

Abstract: An injection molding device includes an injection device including a cylinder, a screw, and a nozzle provided at a front end of the cylinder, for discharging molten resin as the screw advances, a mold including a molded product cavity, and a resin channel between the molded product cavity and a portion abutting the nozzle, a channel pressure measuring device for acquiring channel pressure data in the resin channel, and a determination unit that determines presence/absence of clogging of a gate of the resin channel, based on features of the channel pressure data.

Abstract: There are provided a molding conditions determination assist device and a resin state estimation device including: a quality estimation unit which estimates quality of the mold products by a machine learning on the basis of a detection data; a quality transition storage unit which accumulates the estimated quality of the mold products and stores a quality transition with respect to the accumulated quality of the mold products; a tendency evaluation unit which evaluates a quality change tendency with respect to a prescribed standard quality on the basis of the quality transition; a relationship storage unit which stores a relationship between the quality change tendency and a modification amount of the molding conditions for returning the quality to the standard quality; and a modification conditions determination unit which determines the modification amount of the molding conditions on the basis of the quality change tendency and the relationship.

Abstract: A sound pickup device for picking up a target sound includes: a first input interface that inputs image data generated by a camera; a second input interface that inputs an audio signal output from a microphone array; a controller that determines a sound pickup direction in which the target sound is picked up, based on the image data and the audio signal; and an output interface that outputs information to be presented to the user. The controller determines whether an image indicated by the input image data and an audio sound indicated by the input audio signal are in a predetermined state. When determining that the image and the audio sound are in the predetermined state, the controller causes the output interface to output an instruction to the user, and inputs additional image data and an additional audio signal after the instruction is output, to determine the sound pickup direction.

Abstract: An air-conditioner is provided with a refrigerant circuit and an indoor fan. The refrigerant circuit has a compressor, a first four-way valve, an outdoor heat exchanger, a first expansion valve, a second four-way valve, a third four-way valve, an indoor heat exchanger, and a second expansion valve. The indoor heat exchanger has a first heat exchange portion and a second heat exchange portion. During a cooling operation, in the first heat exchange portion and the second heat exchange portion, a flow of refrigerant with respect to a flow of air sent by the indoor fan is a parallel flow. In a reheating dehumidification operation, in the first heat exchange portion, the flow of refrigerant with respect to the flow of air is the parallel flow, and in the second heat exchange portion, the flow of refrigerant with respect to the flow of air is a counterflow.

Abstract: An imaging system located on a moving body includes an imaging device, a blur correction assembly, and a controller. The blur correction assembly that corrects blur in movement direction of the moving body when the imaging device captures images during movement of the moving body. The controller controls exposure time of the imaging device, based on a movement velocity of the moving body and a correctable blur amount by the blur correction assembly.

Abstract: Provided is a binder composition for a secondary battery with which a slurry composition for a secondary battery having low foaming can be produced, and that can improve handleability of a functional layer or electrode layer formed using the produced slurry composition for a secondary battery. The binder composition for a secondary battery contains a polymer A and a solvent. The polymer A includes an amide group-containing monomer unit and a carboxylic acid ester-containing monomer unit including an alkyl chain having a carbon number of not less than 2 and not more than 9. Content of the carboxylic acid ester-containing monomer unit in the polymer A is not less than 12 mass % and not more than 28 mass %.

Abstract: Provided is a conductive material paste for an electrochemical device electrode with which it is possible to produce a slurry composition that has excellent viscosity stability and can cause an electrochemical device to display excellent cycle characteristics. The conductive material paste contains a fibrous conductive carbon, a triazine skeleton-containing compound, a water-soluble polymer, and water. The amount of the triazine skeleton-containing compound is not less than 1 part by mass and not more than 50 parts by mass per 100 parts by mass of the fibrous conductive carbon, and the amount of the water-soluble polymer is not less than 1 part by mass and not more than 50 parts by mass per 100 parts by mass of the fibrous conductive carbon.

Abstract: In an air-conditioning apparatus, a first flow passage selection device and a second flow passage selection device each are a constant-energized-type three-way valve in which a position of a main valve can be fixed in a de-energized state. When the refrigerant circuit is switched to the cooling circuit by a flow switching device, when at least one of the first flow passage selection device and the second flow passage selection device is in a de-energized state, the first flow passage selection device or the second flow passage selection device in the de-energized state is configured to output refrigerant discharged from the compressor and input therein via the flow switching device and the bypass pipe to a corresponding one of an upper-side outdoor heat exchanger and a lower-side outdoor heat exchanger.

Abstract: Compositions containing one or more amino acids selected from the group consisting of 25 mol % to 45 mol % of leucine, and 20 mol % to 40 mol % of phenylalanine relative to the total content of leucine, lysine, valine, isoleucine, phenylalanine, histidine, and tryptophan, are useful for improving cognitive function, for improving anxiety-like symptoms, and for suppressing cerebral atrophy and are highly safe and can be ingested or administered continuously.

Abstract: The purpose of the present invention is to provide a method for predicting the effectiveness of an angiogenesis inhibitor in a subject suffering from a tumor. Provided is a method comprising a step of testing for the presence or absence of an a mutation or loss of expression of B-Raf and PTEN in a sample of tumor tissue from the subject. By using the presence or absence of or a mutation or loss of expression of B-Raf and PTEN as an indicator, this method enables the antitumor effectiveness of the angiogenesis inhibitor to be predicted without administering the angiogenesis inhibitor to the subject.

Abstract: Provided is a binder composition that can result in high peel strength in an electrode and excellent cycle characteristics in a secondary battery. A binder composition for a non-aqueous secondary battery contains a water-soluble polymer (A) and a water-soluble polymer (B). The water-soluble polymer (A) is formed of one or more types of units selected from the group consisting of unsaturated carboxylic acid monomer units, unsaturated carboxylic acid amide monomer units, unsaturated carboxylic acid ester monomer units, hydroxyl group-containing vinyl monomer units, and vinyl alcohol structural units, and includes a predetermined amount of unsaturated carboxylic acid monomer units. The water-soluble polymer (B) is formed of one or more types of ethylenically unsaturated monomer units, and includes a predetermined amount of sulfo group-containing aromatic vinyl monomer units.

Abstract: A propeller fan includes: a rotation-axis part that serves as a center of rotation; and a plurality of blades provided on an outer circumferential side of the rotation-axis part, the plurality of blades being joined to adjoining blades at leading edges and trailing edges thereof. A first rib projecting towards the center of rotation of the rotation-axis part to surround the rotation-axis part, and second ribs projecting towards the center of rotation to extend from the rotation-axis part toward the first rib are provided on pressure surfaces of the plurality of blades. Among ends of the second ribs in the direction of the center of rotation, the ends distant from the pressure surfaces project away from the pressure surfaces farther than an end of the first rib distant from the pressure surfaces, among the ends of the first rib in the direction of the center of rotation.

Abstract: Provided is a binder composition for a secondary battery with which excellent close adherence is obtained between a substrate and a layer obtained using the binder composition and that can result in a secondary battery having good cycle characteristics. The binder composition contains a polymer and a solvent, wherein the polymer is core-shell particles including a core portion formed of a polymer (a1) and a shell portion formed of a polymer (a2). The polymer (a2) includes specific monomer units with specific amounts, wherein at least one type of monomer unit selected from a monofunctional unsaturated carboxylic acid monomer unit and a monofunctional unsaturated sulfonic acid monomer unit is not less than 0.1 mol and not more than 15,000 mol relative to 1 mol of a monomer unit of a monomer including at least two vinyl functional groups.

Abstract: Provided is a binder composition for lithium ion secondary battery electrode-use that reduces internal resistance of a lithium ion secondary battery while also providing the lithium ion secondary battery with excellent life characteristics. The binder composition contains a copolymer X and a solvent. The copolymer X is obtained from a monomer composition X that contains at least 20.0 mass % and no greater than 75.0 mass % of an ethylenically unsaturated carboxylic acid compound (A) composed of either or both of an ethylenically unsaturated carboxylic acid and an ethylenically unsaturated carboxylic acid salt, and at least 20.0 mass % and no greater than 75.0 mass % of a copolymerizable compound (B) that has an ethylenically unsaturated bond and a solubility of at least 7 g in 100 g of water at 20° C. The copolymer X has a degree of swelling in electrolysis solution of less than 120 mass %.