Abstract: In an air-conditioning, first flow passage selection device and a second flow passage selection device each are a constant-energized-type three-way valve in which a position of a main valve can be fixed in a de-energized state. When the refrigerant circuit is switched to the cooling circuit by a flow switching device, when at least one of the first flow passage selection device and the second flow passage selection device is in a de-energized state, the first flow passage selection device or the second flow passage selection device in the de-energized state is configured to output refrigerant discharged from the compressor and input therein via the flow switching device and the bypass pipe to a corresponding one of an upper-side outdoor heat exchanger and a lower-side outdoor heat exchanger.

Abstract: A sound pickup device for picking up a target sound includes: a first input interface that inputs image data generated by a camera; a second input interface that inputs an audio signal output from a microphone array; a controller that determines a sound pickup direction in which the target sound is picked up, based on the image data and the audio signal; and an output interface that outputs information to be presented to the user. The controller determines whether an image indicated by the input image data and an audio sound indicated by the input audio signal are in a predetermined state. When determining that the image and the audio sound are in the predetermined state, the controller causes the output interface to output an instruction to the user, and inputs additional image data and an additional audio signal after the instruction is output, to determine the sound pickup direction.

Abstract: The present disclosure provides a sound collection device that collects a sound while suppressing noise. The sound collection device includes: a storage that stores first data indicating a feature amount of an image of an object indicating a noise source or a target sound source; and a control circuit that specifies a direction of the noise source by performing a first collation of collating image data generated by a camera with the first data, and performs signal processing on an acoustic signal outputted from a microphone array so as to suppress a sound arriving from the specified direction of the noise source.

Abstract: A sound pickup device is a device that picks up target sound that has been output from an object serving as a sound source. The sound pickup device includes a controller that generates object location information indicating a location of the object on the basis of image data of a camera, generates sound-source location information indicating a location of the sound source on the basis of an acoustic signal of a microphone array, sets a weight for the object location information in accordance with an image capturing state of the camera, and determines a direction in which the target sound is to be picked up on the basis of the object location information, the weight for the object location information, and the sound-source location information.

Abstract: A sound pickup device includes a sound pickup unit, a mounting part, and a communication unit. The sound pickup unit includes a microphone array including a plurality of microphones. The sound pickup unit generates an acoustic signal that corresponds to ambient sound that has been picked up by the microphone array. An electronic device is mounted on the mounting part and the electronic device includes a camera that generates image data by imaging surroundings. The communication unit transmits the acoustic signal to the electronic device.

Abstract: The signal processing device is a signal processing device that collects a target sound output from an object to be a sound source, and includes a communication circuit that inputs image data produced by a camera and an acoustic signal output from a microphone array, and a control circuit that controls a sound collection direction of the acoustic signal in at least any one of a horizontal direction and a vertical direction relative to the microphone array based on at least any one of the image data and the acoustic signal.

Abstract: Biomarkers are provided that predict whether a human subject having a renal cell carcinoma is responsive to a combination therapy comprising lenvatinib or a pharmaceutically acceptable salt thereof (e.g., lenvatinib mesylate) and everolimus. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for and treating a subject having, suspected of having, or at risk of developing a renal cell carcinoma.

Abstract: A heat exchanger includes a plurality of plate-shaped fins disposed at intervals, and a plurality of heat transfer tubes disposed to be inserted into through holes of the fins in a direction perpendicular to the fins. In each of the fins, a starting hole is formed between adjacent through holes, and the starting hole serves as a start point of bending of the fins and has a vertex portion at a bending portion of each fin which is close to an edge thereof. In each of the fins, a cut is made to connect the other edge of the fin and a side of the starting hole which is located opposite to the vertex portion of the starting hole. The above each fin is bent at the vertex portion of the starting hole, by opening the cut from the starting hole.

Abstract: A propeller fan includes a shaft disposed on a rotation axis and a blade disposed adjacent to an outer circumferential surface of the shaft. The blade has a leading edge and a trailing edge. At least one of the leading edge and the trailing edge has a notch. The notch includes a pair of side edge-parts forming an acute included angle and bottom edge-part located between the pair of side edge-parts. The bottom edge-part includes at least one protrusion having an obtuse included angle.

Abstract: A propeller fan includes a boss on a rotation axis, and a blade at an outer circumferential portion of the boss. The blade includes a leading edge and a trailing edge. The blade includes a first area, a first sub-area located inward of the first area, and a second sub-area located outward of the first area. The first area includes a notch formed in the trailing edge. Each of the first sub-area and the second sub-area include plural notches formed in the trailing edge. The notch in the first area is larger than each of the plural notches in each of the first sub-area and the second sub-area.

Abstract: An air conditioner (10) includes a refrigerant circuit (13) and refrigerant. The refrigerant circuit (13) has a compressor (1), a condenser (2), a pressure-regulating valve (3), and an evaporator (4). The refrigerant is R32. The pressure-regulating valve (3) includes a flow path (33) causing the refrigerant flowing from the condenser (2) to flow to the evaporator (4), a pressure reference chamber (S2) partitioned from the flow path (33) and filled with inert gas, and a valve portion (34) disposed in the flow path (33). The pressure-regulating valve (3) is configured to adjust a degree of opening of the valve portion (34) to adjust a flow rate of the refrigerant flowing through the flow path (33). The valve portion (34) is configured to increase the degree of opening when a pressure in the flow path (33) is higher than a pressure in the pressure reference chamber (S2), and reduce the degree of opening when the pressure in the flow path (33) is lower than the pressure in the pressure reference chamber (S2).

Abstract: An air conditioner (10) includes a refrigerant circuit (13) and refrigerant. The refrigerant circuit (13) has a compressor (1), a condenser (2), a pressure-regulating valve (3), and an evaporator (4). The refrigerant is R32. The pressure-regulating valve (3) includes a flow path (33) causing the refrigerant flowing from the condenser (2) to flow to the evaporator (4), a pressure reference chamber (S2) partitioned from the flow path (33) and filled with inert gas, and a valve portion (34) disposed in the flow path (33). The pressure-regulating valve (3) is configured to adjust a degree of opening of the valve portion (34) to adjust a flow rate of the refrigerant flowing through the flow path (33). The valve portion (34) is configured to increase the degree of opening when a pressure in the flow path (33) is higher than a pressure in the pressure reference chamber (S2), and reduce the degree of opening when the pressure in the flow path (33) is lower than the pressure in the pressure reference chamber (S2).

Abstract: The object of the present invention is to provide a nucleic acid agent that can be efficiently delivered to the nervous system, particularly the central nervous system to which the BBB mechanism prevents drug delivery, and can produce an antisense effect on a target transcriptional product at the delivered site, and a composition comprising the same. Provided is a double-stranded nucleic acid complex formed by annealing a first nucleic acid strand capable of hybridizing to part of a target transcriptional product, and has an antisense effect on the target transcriptional product, to a second nucleic acid strand comprising a base sequence complementary to the first nucleic acid strand, and is bound to tocopherol or an analog thereof, cholesterol or an analog thereof, or a substituted or unsubstituted C1-30 alkyl group, a substituted or unsubstituted C2-30 alkenyl group, or a substituted or unsubstituted C1-30 alkoxy group.

Abstract: The present disclosure provides a sound collection device that collects a sound while suppressing noise. The sound collection device includes: a storage that stores first data indicating a feature amount of an image of an object indicating a noise source or a target sound source; and a control circuit that specifies a direction of the noise source by performing a first collation of collating image data generated by a camera with the first data, and performs signal processing on an acoustic signal outputted from a microphone array so as to suppress a sound arriving from the specified direction of the noise source.

Abstract: The signal processing device is a signal processing device that collects a target sound output from an object to be a sound source, and includes a communication circuit that inputs image data produced by a camera and an acoustic signal output from a microphone array, and a control circuit that controls a sound collection direction of the acoustic signal in at least any one of a horizontal direction and a vertical direction relative to the microphone array based on at least any one of the image data and the acoustic signal.

Abstract: Disclosed is a binder composition for a secondary battery which comprises an adhesive polymer and a solvent, wherein a viscosity of the binder composition at a solid concentration of 5.0% by mass is 50 mPa·s or more, and a viscosity of a fraction which is obtained by centrifuging the binder composition at a solid concentration of 5.0% by mass and has a light transmittance of 65% or less is 30 mPa·s or more.

Abstract: A translation device includes a first receiver, a second receiver, a first output unit, and a second output unit. The first receiver receives a first voice and converts the first voice into a first voice signal. The second receiver receives a second voice and converts the second voice into a second voice signal. The first output unit outputs a voice corresponding to second translation data generated based on the second voice signal. The second output unit outputs a voice corresponding to first translation data generated based on the first voice signal. The first receiver is disposed near a mouth of a first user. The first output unit is disposed at a position at which the first output unit is in contact with an ear of the first user. The second receiver and the second output unit are disposed on a head of the first user.

Abstract: Compositions containing one or more amino acids selected from the group consisting of 25 mol % to 45 mol % of leucine, and 20 mol % to 40 mol % of phenylalanine relative to the total content of leucine, lysine, valine, isoleucine, phenylalanine, histidine, and tryptophan, are useful for improving cognitive function, for improving anxiety-like symptoms, and for suppressing cerebral atrophy and are highly safe and can be ingested or administered continuously.

Abstract: An indoor unit of an air-conditioning apparatus eliminates a possibility of condensation on a front panel without deteriorating a quality of design. In an off state, an auxiliary air-directing plate is positioned above an up-down air-directing plate inside an air outlet such that a free end of the auxiliary air-directing plate opposite from one end of the auxiliary air-directing plate fixed to a rotating shaft is positioned closer to a rear surface of a casing than is the rotating shaft. In an on state, the auxiliary air-directing plate is rotated in a direction from the rear surface to a front surface of the casing, and the free end is protruded from the air outlet to an outside of the casing.

Abstract: Provided is a binder composition for a secondary battery with which a slurry composition for a secondary battery having low foaming can be produced, and that can improve handleability of a functional layer or electrode layer formed using the produced slurry composition for a secondary battery. The binder composition for a secondary battery contains a polymer A and a solvent. The polymer A includes an amide group-containing monomer unit and a carboxylic acid ester-containing monomer unit including an alkyl chain having a carbon number of not less than 2 and not more than 9. Content of the carboxylic acid ester-containing monomer unit in the polymer A is not less than 12 mass % and not more than 28 mass %.